|
US3773319A
(en)
|
1971-12-16 |
1973-11-20 |
Fabcor Ind Inc |
Corrugated sheet inverting machine
|
|
US4444887A
(en)
|
1979-12-10 |
1984-04-24 |
Sloan-Kettering Institute |
Process for making human antibody producing B-lymphocytes
|
|
US5179017A
(en)
|
1980-02-25 |
1993-01-12 |
The Trustees Of Columbia University In The City Of New York |
Processes for inserting DNA into eucaryotic cells and for producing proteinaceous materials
|
|
US4634665A
(en)
|
1980-02-25 |
1987-01-06 |
The Trustees Of Columbia University In The City Of New York |
Processes for inserting DNA into eucaryotic cells and for producing proteinaceous materials
|
|
US4399216A
(en)
*
|
1980-02-25 |
1983-08-16 |
The Trustees Of Columbia University |
Processes for inserting DNA into eucaryotic cells and for producing proteinaceous materials
|
|
IE52535B1
(en)
|
1981-02-16 |
1987-12-09 |
Ici Plc |
Continuous release pharmaceutical compositions
|
|
US4716111A
(en)
|
1982-08-11 |
1987-12-29 |
Trustees Of Boston University |
Process for producing human antibodies
|
|
US4510245A
(en)
|
1982-11-18 |
1985-04-09 |
Chiron Corporation |
Adenovirus promoter system
|
|
GB8308235D0
(en)
*
|
1983-03-25 |
1983-05-05 |
Celltech Ltd |
Polypeptides
|
|
US4816567A
(en)
*
|
1983-04-08 |
1989-03-28 |
Genentech, Inc. |
Recombinant immunoglobin preparations
|
|
HUT35524A
(en)
|
1983-08-02 |
1985-07-29 |
Hoechst Ag |
Process for preparing pharmaceutical compositions containing regulatory /regulative/ peptides providing for the retarded release of the active substance
|
|
US6054561A
(en)
|
1984-02-08 |
2000-04-25 |
Chiron Corporation |
Antigen-binding sites of antibody molecules specific for cancer antigens
|
|
EP0154316B1
(en)
|
1984-03-06 |
1989-09-13 |
Takeda Chemical Industries, Ltd. |
Chemically modified lymphokine and production thereof
|
|
US4694778A
(en)
|
1984-05-04 |
1987-09-22 |
Anicon, Inc. |
Chemical vapor deposition wafer boat
|
|
US5807715A
(en)
*
|
1984-08-27 |
1998-09-15 |
The Board Of Trustees Of The Leland Stanford Junior University |
Methods and transformed mammalian lymphocyte cells for producing functional antigen-binding protein including chimeric immunoglobulin
|
|
US5168062A
(en)
*
|
1985-01-30 |
1992-12-01 |
University Of Iowa Research Foundation |
Transfer vectors and microorganisms containing human cytomegalovirus immediate-early promoter-regulatory DNA sequence
|
|
WO1986005807A1
(en)
|
1985-04-01 |
1986-10-09 |
Celltech Limited |
Transformed myeloma cell-line and a process for the expression of a gene coding for a eukaryotic polypeptide employing same
|
|
US4968615A
(en)
*
|
1985-12-18 |
1990-11-06 |
Ciba-Geigy Corporation |
Deoxyribonucleic acid segment from a virus
|
|
GB8601597D0
(en)
*
|
1986-01-23 |
1986-02-26 |
Wilson R H |
Nucleotide sequences
|
|
GB8607679D0
(en)
|
1986-03-27 |
1986-04-30 |
Winter G P |
Recombinant dna product
|
|
US5225539A
(en)
|
1986-03-27 |
1993-07-06 |
Medical Research Council |
Recombinant altered antibodies and methods of making altered antibodies
|
|
US4902505A
(en)
|
1986-07-30 |
1990-02-20 |
Alkermes |
Chimeric peptides for neuropeptide delivery through the blood-brain barrier
|
|
US4946778A
(en)
|
1987-09-21 |
1990-08-07 |
Genex Corporation |
Single polypeptide chain binding molecules
|
|
US5116742A
(en)
|
1986-12-03 |
1992-05-26 |
University Patents, Inc. |
RNA ribozyme restriction endoribonucleases and methods
|
|
US5258498A
(en)
|
1987-05-21 |
1993-11-02 |
Creative Biomolecules, Inc. |
Polypeptide linkers for production of biosynthetic proteins
|
|
US4904582A
(en)
|
1987-06-11 |
1990-02-27 |
Synthetic Genetics |
Novel amphiphilic nucleic acid conjugates
|
|
US5892019A
(en)
|
1987-07-15 |
1999-04-06 |
The United States Of America, As Represented By The Department Of Health And Human Services |
Production of a single-gene-encoded immunoglobulin
|
|
GB8717430D0
(en)
|
1987-07-23 |
1987-08-26 |
Celltech Ltd |
Recombinant dna product
|
|
US5336603A
(en)
*
|
1987-10-02 |
1994-08-09 |
Genentech, Inc. |
CD4 adheson variants
|
|
JP3040121B2
(ja)
|
1988-01-12 |
2000-05-08 |
ジェネンテク，インコーポレイテッド |
増殖因子レセプターの機能を阻害することにより腫瘍細胞を処置する方法
|
|
GB8809129D0
(en)
|
1988-04-18 |
1988-05-18 |
Celltech Ltd |
Recombinant dna methods vectors and host cells
|
|
WO1989012624A2
(en)
|
1988-06-14 |
1989-12-28 |
Cetus Corporation |
Coupling agents and sterically hindered disulfide linked conjugates prepared therefrom
|
|
CA1340288C
(en)
|
1988-09-02 |
1998-12-29 |
Robert Charles Ladner |
Generation and selection of novel binding proteins
|
|
US5223409A
(en)
|
1988-09-02 |
1993-06-29 |
Protein Engineering Corp. |
Directed evolution of novel binding proteins
|
|
EP0368684B2
(en)
|
1988-11-11 |
2004-09-29 |
Medical Research Council |
Cloning immunoglobulin variable domain sequences.
|
|
US5175384A
(en)
|
1988-12-05 |
1992-12-29 |
Genpharm International |
Transgenic mice depleted in mature t-cells and methods for making transgenic mice
|
|
DE68925966T2
(de)
|
1988-12-22 |
1996-08-29 |
Kirin Amgen Inc |
Chemisch modifizierte granulocytenkolonie erregender faktor
|
|
US5530101A
(en)
|
1988-12-28 |
1996-06-25 |
Protein Design Labs, Inc. |
Humanized immunoglobulins
|
|
US5225538A
(en)
|
1989-02-23 |
1993-07-06 |
Genentech, Inc. |
Lymphocyte homing receptor/immunoglobulin fusion proteins
|
|
IE63847B1
(en)
|
1989-05-05 |
1995-06-14 |
Res Dev Foundation |
A novel antibody delivery system for biological response modifiers
|
|
DE69031120T2
(de)
|
1989-05-19 |
1998-01-15 |
Genentech, Inc., South San Francisco, Calif. |
Her2 extrazellulare domäne
|
|
US5413923A
(en)
|
1989-07-25 |
1995-05-09 |
Cell Genesys, Inc. |
Homologous recombination for universal donor cells and chimeric mammalian hosts
|
|
US5180820A
(en)
|
1989-08-30 |
1993-01-19 |
Barde Yves Alain |
Brain-derived neurotrophic factor
|
|
US5605690A
(en)
|
1989-09-05 |
1997-02-25 |
Immunex Corporation |
Methods of lowering active TNF-α levels in mammals using tumor necrosis factor receptor
|
|
GB8928874D0
(en)
|
1989-12-21 |
1990-02-28 |
Celltech Ltd |
Humanised antibodies
|
|
WO1991010737A1
(en)
|
1990-01-11 |
1991-07-25 |
Molecular Affinities Corporation |
Production of antibodies using gene libraries
|
|
US5780225A
(en)
*
|
1990-01-12 |
1998-07-14 |
Stratagene |
Method for generating libaries of antibody genes comprising amplification of diverse antibody DNAs and methods for using these libraries for the production of diverse antigen combining molecules
|
|
US6075181A
(en)
|
1990-01-12 |
2000-06-13 |
Abgenix, Inc. |
Human antibodies derived from immunized xenomice
|
|
ATE139258T1
(de)
|
1990-01-12 |
1996-06-15 |
Cell Genesys Inc |
Erzeugung xenogener antikörper
|
|
WO1996033735A1
(en)
|
1995-04-27 |
1996-10-31 |
Abgenix, Inc. |
Human antibodies derived from immunized xenomice
|
|
US6150584A
(en)
*
|
1990-01-12 |
2000-11-21 |
Abgenix, Inc. |
Human antibodies derived from immunized xenomice
|
|
US5314995A
(en)
*
|
1990-01-22 |
1994-05-24 |
Oncogen |
Therapeutic interleukin-2-antibody based fusion proteins
|
|
CA2078689C
(en)
|
1990-03-20 |
2003-02-11 |
Sherie L. Morrison |
Chimeric antibodies with receptor binding ligands in place of their constant region
|
|
US5427908A
(en)
|
1990-05-01 |
1995-06-27 |
Affymax Technologies N.V. |
Recombinant library screening methods
|
|
US5219837A
(en)
*
|
1990-06-21 |
1993-06-15 |
Trustees Of The University Of Pennsylvania |
Method of stimulating myelination of cells
|
|
GB9015198D0
(en)
|
1990-07-10 |
1990-08-29 |
Brien Caroline J O |
Binding substance
|
|
US5532351A
(en)
|
1990-07-12 |
1996-07-02 |
Arch Development Corporation |
Nucleic acid sequences encoding OMGP
|
|
US5545806A
(en)
*
|
1990-08-29 |
1996-08-13 |
Genpharm International, Inc. |
Ransgenic non-human animals for producing heterologous antibodies
|
|
DK0814159T3
(da)
|
1990-08-29 |
2005-10-24 |
Genpharm Int |
Transgene, ikke-humane dyr, der er i stand til at danne heterologe antistoffer
|
|
US5633425A
(en)
|
1990-08-29 |
1997-05-27 |
Genpharm International, Inc. |
Transgenic non-human animals capable of producing heterologous antibodies
|
|
US5625126A
(en)
*
|
1990-08-29 |
1997-04-29 |
Genpharm International, Inc. |
Transgenic non-human animals for producing heterologous antibodies
|
|
US5814318A
(en)
|
1990-08-29 |
1998-09-29 |
Genpharm International Inc. |
Transgenic non-human animals for producing heterologous antibodies
|
|
US5661016A
(en)
|
1990-08-29 |
1997-08-26 |
Genpharm International Inc. |
Transgenic non-human animals capable of producing heterologous antibodies of various isotypes
|
|
US5698426A
(en)
*
|
1990-09-28 |
1997-12-16 |
Ixsys, Incorporated |
Surface expression libraries of heteromeric receptors
|
|
EP1149913A1
(en)
|
1990-11-09 |
2001-10-31 |
GILLIES, Stephen D. |
Cytokine immunoconjugates
|
|
US5252714A
(en)
|
1990-11-28 |
1993-10-12 |
The University Of Alabama In Huntsville |
Preparation and use of polyethylene glycol propionaldehyde
|
|
ES2113940T3
(es)
*
|
1990-12-03 |
1998-05-16 |
Genentech Inc |
Metodo de enriquecimiento para variantes de proteinas con propiedades de union alteradas.
|
|
ATE269401T1
(de)
|
1991-04-10 |
2004-07-15 |
Scripps Research Inst |
Bibliotheken heterodimerer rezeptoren mittels phagemiden
|
|
DE69233482T2
(de)
|
1991-05-17 |
2006-01-12 |
Merck & Co., Inc. |
Verfahren zur Verminderung der Immunogenität der variablen Antikörperdomänen
|
|
CA2110799A1
(en)
|
1991-06-14 |
1992-12-23 |
Arnold H. Horwitz |
Microbially-produced antibody fragments and their conjugates
|
|
IE922437A1
(en)
|
1991-07-25 |
1993-01-27 |
Idec Pharma Corp |
Recombinant antibodies for human therapy
|
|
US5756096A
(en)
*
|
1991-07-25 |
1998-05-26 |
Idec Pharmaceuticals Corporation |
Recombinant antibodies for human therapy
|
|
US5565332A
(en)
*
|
1991-09-23 |
1996-10-15 |
Medical Research Council |
Production of chimeric antibodies - a combinatorial approach
|
|
US5885793A
(en)
|
1991-12-02 |
1999-03-23 |
Medical Research Council |
Production of anti-self antibodies from antibody segment repertoires and displayed on phage
|
|
DE69333082T2
(de)
*
|
1992-02-11 |
2004-05-06 |
Cell Genesys, Inc., Foster City |
Erzielen von homozygotem durch zielgerichtete genetische ereignisse
|
|
US5733743A
(en)
|
1992-03-24 |
1998-03-31 |
Cambridge Antibody Technology Limited |
Methods for producing members of specific binding pairs
|
|
US5639641A
(en)
|
1992-09-09 |
1997-06-17 |
Immunogen Inc. |
Resurfacing of rodent antibodies
|
|
US5837821A
(en)
|
1992-11-04 |
1998-11-17 |
City Of Hope |
Antibody construct
|
|
ES2088838T3
(es)
|
1992-11-13 |
2004-01-01 |
Idec Pharmaceuticals Corporation |
Secuencias kozak de consenso totalmente alteradas destinadas a la expresion en los mamiferos.
|
|
US5468872A
(en)
|
1993-09-16 |
1995-11-21 |
Cephalon, Inc. |
K-252a functional derivatives potentiate neurotrophin-3 for the treatment of neurological disorders
|
|
WO1995014930A1
(en)
|
1993-11-23 |
1995-06-01 |
Genentech, Inc. |
Kinase receptor activation assay
|
|
US5753225A
(en)
|
1993-12-03 |
1998-05-19 |
The Regents Of The University Of California |
Antibodies that mimic actions of neurotrophins
|
|
JPH09506262A
(ja)
|
1993-12-08 |
1997-06-24 |
ジェンザイム・コーポレイション |
特異的抗体の製造方法
|
|
ATE243745T1
(de)
|
1994-01-31 |
2003-07-15 |
Univ Boston |
Bibliotheken aus polyklonalen antikörpern
|
|
GB9402331D0
(en)
|
1994-02-07 |
1994-03-30 |
Univ Mcgill |
Nerve growth factor structural analogs and their uses
|
|
US5877016A
(en)
|
1994-03-18 |
1999-03-02 |
Genentech, Inc. |
Human trk receptors and neurotrophic factor inhibitors
|
|
DE4447588C2
(de)
|
1994-05-03 |
1997-11-20 |
Omer Osama Dr Dr Med |
Pflanzliches Arzneimittel zur Behandlung von chronischen und allergischen Rhino-Sino-Bronchitiden
|
|
US5516637A
(en)
*
|
1994-06-10 |
1996-05-14 |
Dade International Inc. |
Method involving display of protein binding pairs on the surface of bacterial pili and bacteriophage
|
|
WO1996012717A1
(en)
|
1994-10-25 |
1996-05-02 |
Toyama Chemical Co., Ltd. |
Potentiator for nerve growth factor activity containing 1,2-ethanediol derivative or salt thereof
|
|
US5770577A
(en)
|
1994-11-14 |
1998-06-23 |
Amgen Inc. |
BDNF and NT-3 polypeptides selectively linked to polyethylene glycol
|
|
US6130364A
(en)
|
1995-03-29 |
2000-10-10 |
Abgenix, Inc. |
Production of antibodies using Cre-mediated site-specific recombination
|
|
US6280964B1
(en)
|
1995-04-14 |
2001-08-28 |
The Regents Of The University Of California |
Binding sites for phosphotyrosine binding domains
|
|
WO1996034096A1
(en)
|
1995-04-28 |
1996-10-31 |
Abgenix, Inc. |
Human antibodies derived from immunized xenomice
|
|
US5811524A
(en)
*
|
1995-06-07 |
1998-09-22 |
Idec Pharmaceuticals Corporation |
Neutralizing high affinity human monoclonal antibodies specific to RSV F-protein and methods for their manufacture and therapeutic use thereof
|
|
DE69638269D1
(de)
|
1995-06-14 |
2010-11-18 |
Univ California |
Hochaffine humane antikörper gegen tumorantigene
|
|
US5707829A
(en)
|
1995-08-11 |
1998-01-13 |
Genetics Institute, Inc. |
DNA sequences and secreted proteins encoded thereby
|
|
IT235676Y1
(it)
|
1995-07-27 |
2000-07-12 |
Felice Gaudioso |
Allestimenti per lo svolgimento del gioco wormhole action match.
|
|
GB9525180D0
(en)
|
1995-12-08 |
1996-02-07 |
Univ Mcgill |
Design of hormone-like antibodies with agonistic and antagonistic fuctions
|
|
JP2978435B2
(ja)
|
1996-01-24 |
1999-11-15 |
チッソ株式会社 |
アクリロキシプロピルシランの製造方法
|
|
US6455277B1
(en)
|
1996-04-22 |
2002-09-24 |
Amgen Inc. |
Polynucleotides encoding human glial cell line-derived neurotrophic factor receptor polypeptides
|
|
JP2000501416A
(ja)
|
1996-04-26 |
2000-02-08 |
ユニバーシティー オブ オタワ |
ニューロン病を治療し予防するための、治療法および薬物のスクリーニング法
|
|
WO1997049406A1
(en)
|
1996-06-25 |
1997-12-31 |
Cephalon, Inc. |
Use of k-252a derivative for the treatment of peripheral or central nerve disorders, and cytokine overproduction
|
|
EP0938556B1
(en)
*
|
1996-07-12 |
2005-03-09 |
Genentech, Inc. |
Gamma-heregulin
|
|
ZA976326B
(en)
|
1996-07-19 |
1998-02-03 |
Amgen Inc |
Analogs of cationic proteins.
|
|
BR9712978A
(pt)
*
|
1996-09-11 |
2000-04-18 |
Gen Hospital Corp |
Vìrus de dna de não-mamìferos possuindo uma proteìna de revestimento alterada
|
|
CN1233963A
(zh)
|
1996-09-13 |
1999-11-03 |
有限会社最先端医学研究所 |
神经营养因子的眼科用组合物、视神经机能障碍治疗药和视神经机能障碍治疗方法
|
|
US6420140B1
(en)
|
1996-10-11 |
2002-07-16 |
Abgenix, Inc. |
Production of multimeric protein by cell fusion method
|
|
US5916771A
(en)
|
1996-10-11 |
1999-06-29 |
Abgenix, Inc. |
Production of a multimeric protein by cell fusion method
|
|
US20070213290A1
(en)
|
1996-10-17 |
2007-09-13 |
Kingsman Alan J |
Neurite regeneration
|
|
US6156728A
(en)
|
1996-11-01 |
2000-12-05 |
Genentech, Inc. |
Treatment of inner ear hair cells
|
|
US6593290B1
(en)
|
1996-11-01 |
2003-07-15 |
Genentech, Inc. |
Treatment of inner ear hair cells
|
|
JP4215172B2
(ja)
|
1996-12-03 |
2009-01-28 |
アムジェン フレモント インク． |
複数のＶ▲下Ｈ▼およびＶ▲下κ▼領域を含むヒトＩｇ遺伝子座を有するトランスジェニック哺乳動物、ならびにそれから産生される抗体
|
|
JP4128227B2
(ja)
|
1997-03-14 |
2008-07-30 |
バイオジェン・アイデック・インコーポレイテッド |
哺乳類細胞内の特定部位に相同組換えによって遺伝子を組み込む方法とそれを実施するためのベクター
|
|
US20020137890A1
(en)
|
1997-03-31 |
2002-09-26 |
Genentech, Inc. |
Secreted and transmembrane polypeptides and nucleic acids encoding the same
|
|
KR100663319B1
(ko)
|
1997-04-14 |
2007-01-02 |
마이크로메트 에이지 |
인간 17-1에이항원에 대해 특이성을 갖는 인간항체 및 그용도
|
|
US6235883B1
(en)
|
1997-05-05 |
2001-05-22 |
Abgenix, Inc. |
Human monoclonal antibodies to epidermal growth factor receptor
|
|
EP0983303B1
(en)
|
1997-05-21 |
2006-03-08 |
Biovation Limited |
Method for the production of non-immunogenic proteins
|
|
US6190370B1
(en)
|
1997-07-25 |
2001-02-20 |
Arrow International, Inc. |
Devices, systems and methods for determining proper placement of epidural catheters
|
|
JP2001512003A
(ja)
|
1997-08-04 |
2001-08-21 |
ミレニアム ファーマシューティカルズ インク． |
Ｔａｎｇｏ−７８、Ｔａｎｇｏ−７９およびＴａｎｇｏ−８１ポリペプチド、Ｔａｎｇｏ−７８、Ｔａｎｇｏ−７９およびＴａｎｇｏ−８１をコードする核酸分子ならびにそれらの使用
|
|
US20020112251A1
(en)
*
|
1997-08-04 |
2002-08-15 |
Mccarthy Sean A. |
Novel genes encoding proteins having prognostic, diagnostic, preventive, therapeutic and other uses
|
|
AU741060C
(en)
|
1997-09-17 |
2002-09-19 |
Genentech Inc. |
Secreted and transmembrane polypeptides and nucleic acids encoding the same
|
|
US6974689B1
(en)
*
|
1997-09-18 |
2005-12-13 |
Genentech, Inc. |
Nucleic acid encoding PRO211 polypeptides
|
|
DK1205546T3
(da)
*
|
1997-10-24 |
2006-04-03 |
Genentech Inc |
Polypeptider og nucleinsyrer kodende derfor
|
|
FR2776661B1
(fr)
|
1998-03-26 |
2002-04-05 |
Centre Nat Rech Scient |
Polypeptide immunoreactif du recepteur trka du ngf et utilisations
|
|
US7282482B2
(en)
|
1998-04-08 |
2007-10-16 |
The Regents Of The University Of California |
NGF for the prevention of demyelination in the nervous system
|
|
IL141535A0
(en)
|
1998-09-16 |
2002-03-10 |
Genentech Inc |
Secreted and transmembrane polypeptides and nucleic acids encoding the same
|
|
CZ304224B6
(cs)
|
1998-11-06 |
2014-01-15 |
Schwab |
Monoklonální protilátka
|
|
CA2342967A1
(en)
|
1998-12-08 |
2000-06-15 |
Biovation Limited |
Modifying protein immunogenicity
|
|
CA2383592A1
(en)
|
1999-03-31 |
2000-10-05 |
Curagen Corporation |
2384891 acids including open reading frames encoding polypeptides; orfx
|
|
US7034132B2
(en)
|
2001-06-04 |
2006-04-25 |
Anderson David W |
Therapeutic polypeptides, nucleic acids encoding same, and methods of use
|
|
US20040067490A1
(en)
*
|
2001-09-07 |
2004-04-08 |
Mei Zhong |
Therapeutic polypeptides, nucleic acids encoding same, and methods of use
|
|
US6949245B1
(en)
|
1999-06-25 |
2005-09-27 |
Genentech, Inc. |
Humanized anti-ErbB2 antibodies and treatment with anti-ErbB2 antibodies
|
|
IL147271A0
(en)
|
1999-07-02 |
2002-08-14 |
Genentech Inc |
Compounds that bind her2
|
|
AU2883900A
(en)
|
1999-07-07 |
2001-01-30 |
Genentech Inc. |
Secreted and transmembrane polypeptides and nucleic acids encoding the same
|
|
AU6181200A
(en)
|
1999-07-29 |
2001-02-19 |
Helix Research Institute |
Stomach cancer-associated gene
|
|
EP1074617A3
(en)
|
1999-07-29 |
2004-04-21 |
Research Association for Biotechnology |
Primers for synthesising full-length cDNA and their use
|
|
EP1206543A2
(en)
*
|
1999-08-17 |
2002-05-22 |
Incyte Genomics, Inc. |
Membrane associated proteins
|
|
US6461414B1
(en)
|
1999-10-29 |
2002-10-08 |
Baker Hughes Incorporated |
Foam monitoring and control system
|
|
CA2496312A1
(en)
|
1999-12-01 |
2001-06-07 |
Kevin P. Baker |
Colon tumour marker pro4799 polypeptides and nucleic acids encoding the same
|
|
US6680209B1
(en)
|
1999-12-06 |
2004-01-20 |
Biosite, Incorporated |
Human antibodies as diagnostic reagents
|
|
US20040252299A9
(en)
*
|
2000-01-07 |
2004-12-16 |
Lemmo Anthony V. |
Apparatus and method for high-throughput preparation and spectroscopic classification and characterization of compositions
|
|
JP4763207B2
(ja)
|
2000-01-12 |
2011-08-31 |
イェール ユニバーシティー |
軸索成長のｎｏｇｏレセプター媒介妨害
|
|
US7119165B2
(en)
|
2000-01-12 |
2006-10-10 |
Yale University |
Nogo receptor-mediated blockade of axonal growth
|
|
WO2001052843A1
(en)
|
2000-01-18 |
2001-07-26 |
Mcgill University |
β-TURN PEPTIDOMIMETIC CYCLIC COMPOUNDS
|
|
CA2398396A1
(en)
|
2000-01-25 |
2001-08-02 |
Hyseq, Inc. |
Methods and materials relating to transforming growth factor alpha-like polypeptides and polynucleotides
|
|
CA2393616A1
(en)
|
2000-01-31 |
2001-08-02 |
Human Genome Sciences, Inc. |
Nucleic acids, proteins, and antibodies
|
|
CA2397839A1
(en)
|
2000-01-31 |
2001-08-02 |
Human Genome Sciences, Inc. |
Nucleic acids, proteins, and antibodies
|
|
WO2001059063A2
(en)
|
2000-01-31 |
2001-08-16 |
Human Genome Sciences, Inc. |
Nucleic acids, proteins, and antibodies
|
|
EP1254269A4
(en)
|
2000-02-03 |
2004-10-27 |
Nuvelo Inc |
METHODS AND MATERIALS IN CONNECTION WITH POLYPEPTIDES AND POLYNUCLEOTIDS, WHICH LIKE NEURONAL GUIDE MOLECULES
|
|
CN1426422A
(zh)
|
2000-02-29 |
2003-06-25 |
株式会社Ltt研究所 |
修饰的bdnf
|
|
EP2857516B1
(en)
|
2000-04-11 |
2017-06-14 |
Genentech, Inc. |
Multivalent antibodies and uses therefor
|
|
AU2001266787A1
(en)
|
2000-06-07 |
2002-01-08 |
Human Genome Sciences, Inc. |
Nucleic acids, proteins, and antibodies
|
|
US6430914B1
(en)
|
2000-06-29 |
2002-08-13 |
Foster Wheeler Energy Corporation |
Combined cycle power generation plant and method of operating such a plant
|
|
US20040010118A1
(en)
|
2000-08-16 |
2004-01-15 |
Zerhusen Bryan D. |
Novel proteins and nucleic acids encoding same
|
|
CN1474869A
(zh)
|
2000-09-13 |
2004-02-11 |
ʷ��˿�������ȳ�ķ����˾ |
新型化合物
|
|
WO2002029058A2
(en)
|
2000-10-05 |
2002-04-11 |
Curagen Corporation |
Human proteins, polynucleotides encoding them and methods of using the same
|
|
DE60141409D1
(de)
|
2000-10-06 |
2010-04-08 |
Biogen Idec Inc |
Homologe des nogo rezeptors
|
|
ATE352040T1
(de)
|
2000-11-17 |
2007-02-15 |
Univ Rochester |
In-vitro verfahren zur herstellung und identifizierung von immunglobulin moleküle in eukaryotischen zellen
|
|
CA2402459A1
(en)
|
2000-12-01 |
2002-06-06 |
Central Institute For Experimental Animals |
Method of producing a mouse suitable for engraftment, differentiation and proliferation of heterologous cells, mouse produced by this method and use of the mouse
|
|
US20030216558A1
(en)
|
2000-12-22 |
2003-11-20 |
Morris David W. |
Novel compositions and methods for cancer
|
|
WO2002068579A2
(en)
|
2001-01-10 |
2002-09-06 |
Pe Corporation (Ny) |
Kits, such as nucleic acid arrays, comprising a majority of human exons or transcripts, for detecting expression and other uses thereof
|
|
US7319139B2
(en)
|
2001-01-29 |
2008-01-15 |
Biogen Idec, Inc. |
TAG-72 specific CH2 domain deleted antibodies
|
|
CA2436092A1
(en)
|
2001-01-29 |
2002-08-08 |
Idec Pharmaceutical Corporation |
Modified antibodies and methods of use
|
|
WO2003008583A2
(en)
|
2001-03-02 |
2003-01-30 |
Sagres Discovery |
Novel compositions and methods for cancer
|
|
EP1401858A4
(en)
|
2001-06-04 |
2005-12-21 |
Curagen Corp |
THERAPEUTIC POLYPEPTIDES, NUCLEIC ACIDS COATING THEREOF AND METHOD OF USE
|
|
US20030162734A1
(en)
|
2001-06-28 |
2003-08-28 |
Miller Carol A. |
Modulation of DENN-MADD expression and interactions for treating neurological disorders
|
|
US7223558B2
(en)
*
|
2001-07-11 |
2007-05-29 |
Bristol-Myers Squibb Company |
Polynucleotides encoding three novel human cell surface proteins with leucine rich repeats and immunologobulin folds, BGS2, 3, and 4 and variants thereof
|
|
US20030226155A1
(en)
|
2001-08-30 |
2003-12-04 |
Biorexis Pharmaceutical Corporation |
Modified transferrin-antibody fusion proteins
|
|
US20040142325A1
(en)
|
2001-09-14 |
2004-07-22 |
Liat Mintz |
Methods and systems for annotating biomolecular sequences
|
|
US20050123990A1
(en)
*
|
2001-09-26 |
2005-06-09 |
Incyte Corporation |
Membrane associated proteins
|
|
AU2002365258A1
(en)
|
2001-10-12 |
2003-09-02 |
University Of Vermont And State Agricultural College |
Binding peptides specific for the extracellular domain of erbb2 and uses therefor
|
|
AU2002337916A1
(en)
|
2001-10-22 |
2003-05-06 |
Exelixis, Inc. |
Modifier of the p53 pathway and methods of use
|
|
US7309485B2
(en)
|
2001-12-03 |
2007-12-18 |
Children's Medical Center Corporation |
Reducing myelin-mediated inhibition of axon regeneration
|
|
EP1504099A4
(en)
|
2001-12-10 |
2006-05-10 |
Nuvelo Inc |
NEW NUCLEIC ACIDS AND POLYPEPTIDES
|
|
AU2003224638A1
(en)
|
2002-03-01 |
2003-09-16 |
Exelixis, Inc. |
PDPK1s AS MODIFIERS OF THE p53 PATHWAY AND METHODS OF USE
|
|
CA2481074A1
(en)
|
2002-04-05 |
2003-10-23 |
Amgen Inc. |
Human anti-opgl neutralizing antibodies as selective opgl pathway inhibitors
|
|
US7077522B2
(en)
|
2002-05-03 |
2006-07-18 |
University Of Rochester |
Sharpness metric for vision quality
|
|
US6794785B2
(en)
|
2002-06-26 |
2004-09-21 |
Denso Corporation |
Alternator for vehicles
|
|
DK1534736T3
(da)
|
2002-08-10 |
2010-09-20 |
Biogen Idec Inc |
Nogo-receptorantagonister
|
|
PL377091A1
(pl)
|
2002-09-06 |
2006-01-23 |
Amgen, Inc. |
Ludzkie monoklonalne przeciwciało przeciw-IL-1R1, o właściwościach terapeutycznych
|
|
US6919426B2
(en)
|
2002-09-19 |
2005-07-19 |
Amgen Inc. |
Peptides and related molecules that modulate nerve growth factor activity
|
|
US7816497B2
(en)
|
2002-10-30 |
2010-10-19 |
University Of Kentucky |
Compositions and methods for inhibiting drusen complement components C3a and C5a for the treatment of age-related macular degeneration
|
|
US20040186044A1
(en)
|
2002-11-06 |
2004-09-23 |
Cosgaya Jose Miguel |
Modulation of myelination by interaction with P75 and TRK receptors
|
|
US7388079B2
(en)
|
2002-11-27 |
2008-06-17 |
The Regents Of The University Of California |
Delivery of pharmaceutical agents via the human insulin receptor
|
|
PL1606409T3
(pl)
*
|
2003-03-19 |
2011-02-28 |
Biogen Ma Inc |
Białko wiążące receptor Nogo
|
|
PL380274A1
(pl)
|
2003-08-07 |
2007-01-22 |
Biogen Idec Ma Inc. |
Antagoniści receptora Nogo
|
|
AU2004266159A1
(en)
|
2003-08-22 |
2005-03-03 |
Biogen Idec Ma Inc. |
Improved antibodies having altered effector function and methods for making the same
|
|
WO2005021579A2
(en)
|
2003-08-28 |
2005-03-10 |
Biorexis Pharmaceutical Corporation |
Epo mimetic peptides and fusion proteins
|
|
US7205387B2
(en)
|
2003-08-28 |
2007-04-17 |
Agency For Science, Technology And Research |
Recombinant polypeptide useful for neurotrophin receptor mediated gene delivery and as neurotrophin agonist
|
|
US7288638B2
(en)
|
2003-10-10 |
2007-10-30 |
Bristol-Myers Squibb Company |
Fully human antibodies against human 4-1BB
|
|
ATE536376T1
(de)
|
2003-12-23 |
2011-12-15 |
Crucell Holland Bv |
Humanes bindungsmolekül gegen cd1a
|
|
AU2005213965B2
(en)
|
2004-02-12 |
2009-11-19 |
Lexicon Pharmaceuticals, Inc. |
Gene disruptions, compositions and methods relating thereto
|
|
US20050214288A1
(en)
*
|
2004-03-26 |
2005-09-29 |
Human Genome Sciences, Inc. |
Antibodies against Nogo receptor
|
|
WO2005097184A2
(en)
*
|
2004-03-26 |
2005-10-20 |
Human Genome Sciences, Inc. |
Antibodies against nogo receptor
|
|
AU2005232657B2
(en)
|
2004-04-08 |
2010-12-16 |
David B. Agus |
ErbB antagonists for pain therapy
|
|
PL1776136T3
(pl)
|
2004-06-24 |
2013-03-29 |
Biogen Ma Inc |
Leczenie stanów związanych z demielinizacją
|
|
US20060009288A1
(en)
*
|
2004-07-07 |
2006-01-12 |
Devos John A |
Conveying information to an interrogator using resonant and parasitic radio frequency circuits
|
|
US7846438B2
(en)
|
2004-08-03 |
2010-12-07 |
Biogen Idec Ma Inc. |
Methods of promoting neurite outgrowth with soluble TAJ polypeptides
|
|
JO3000B1
(ar)
|
2004-10-20 |
2016-09-05 |
Genentech Inc |
مركبات أجسام مضادة .
|
|
AR054260A1
(es)
|
2005-04-26 |
2007-06-13 |
Rinat Neuroscience Corp |
Metodos de tratamiento de enfermedades de la neurona motora inferior y composiciones utilizadas en los mismos
|
|
JP2008540339A
(ja)
|
2005-04-29 |
2008-11-20 |
ワイス |
Ｎｏｇｏレセプター機能モチーフおよびそれに関するペプチド模倣物、ならびにそれらを使用する方法
|
|
CA2609077A1
(en)
|
2005-05-16 |
2006-12-28 |
Mcgill University |
Lgi, lingo and p75ntr family members: novel modulators of neuronal growth
|
|
AR053401A1
(es)
|
2005-06-06 |
2007-05-02 |
Wyeth Corp |
Anticuerpos monoclonales anti- trkb y usos de los mismos
|
|
WO2006133353A2
(en)
|
2005-06-08 |
2006-12-14 |
The University Of North Carolina At Chapel Hill |
Methods of facilitating neural cell survival using non-peptide and peptide bdnf neurotrophin mimetics
|
|
WO2006133533A1
(en)
|
2005-06-16 |
2006-12-21 |
University Technologies International Inc. |
A treatment for short bowel syndrome
|
|
SG10201508322SA
(en)
|
2005-07-08 |
2015-11-27 |
Biogen Ma Inc |
Sp35 antibodies and uses thereof
|
|
US7612181B2
(en)
|
2005-08-19 |
2009-11-03 |
Abbott Laboratories |
Dual variable domain immunoglobulin and uses thereof
|
|
JP2009513666A
(ja)
|
2005-10-27 |
2009-04-02 |
バイオジェン・アイデック・エムエイ・インコーポレイテッド |
希乏突起神経膠細胞−ミエリン糖タンパク質組成物およびその使用方法
|
|
EP1959979A4
(en)
|
2005-11-04 |
2010-01-27 |
Biogen Idec Inc |
PROCESS FOR PROMOTING AXON GROWTH AND SURVIVAL OF DOPAMINERGIC NEURONS
|
|
NZ569428A
(en)
|
2005-12-02 |
2012-11-30 |
Biogen Idec Inc |
Treatment of conditions involving demyelination with a Sp35 antagonist
|
|
US20070186296A1
(en)
|
2006-02-02 |
2007-08-09 |
Wyeth |
Cloning, characterization, and application of tnfrsf19 in neurological disorders
|
|
CN101405297A
(zh)
|
2006-02-03 |
2009-04-08 |
惠氏公司 |
Lingo-1结构
|
|
WO2007098283A2
(en)
|
2006-02-27 |
2007-08-30 |
Biogen Idec Ma Inc. |
Use of antagonists of maif receptor complex molecules and neurotrophic factors for treatment of neurological diseases and disorders
|
|
EP2068866A4
(en)
*
|
2006-07-24 |
2010-04-07 |
Biogen Idec Inc |
METHODS FOR PROMOTING MYELINIZATION, NEURONAL SURVIVAL AND DIFFERENTIATION OF OLIGODENDROCYTES BY ADMINISTERING SP35 OR TRKA ANTAGONISTS
|
|
ATE502960T1
(de)
|
2006-11-17 |
2011-04-15 |
Novartis Ag |
Lingo bindende moleküle und pharmazeutische verwendung davon
|
|
US8128926B2
(en)
*
|
2007-01-09 |
2012-03-06 |
Biogen Idec Ma Inc. |
Sp35 antibodies and uses thereof
|
|
MX2009007375A
(es)
|
2007-01-09 |
2009-07-21 |
Biogen Idec Inc |
Anticuerpos sp35 y usos de los mismos.
|
|
US20100297121A1
(en)
*
|
2007-10-11 |
2010-11-25 |
Biogen Idec Ma Inc. |
Methods for Treating Pressure Induced Optic Neuropathy, Preventing Neuronal Degeneration and Promoting Neuronal Cell Survival Via Administration of LINGO-1 Antagonists and TrkB Agonists
|
|
EP2217697B1
(en)
|
2007-11-08 |
2015-06-10 |
Biogen MA Inc. |
Use of lingo-4 antagonists in the treatment of conditions involving demyelination
|
|
EP2732823B1
(en)
|
2008-06-25 |
2019-08-07 |
H. Lundbeck A/S |
Modulation of the TrpV : Vps10p-domain receptor system for the treatment of pain
|
|
EA201170028A1
(ru)
|
2008-07-02 |
2011-12-30 |
Эмерджент Продакт Дивелопмент Сиэтл, Ллс |
СВЯЗЫВАЮЩИЕ НЕСКОЛЬКО МИШЕНЕЙ БЕЛКИ, ОБЛАДАЮЩИЕ АНТАГОНИСТИЧЕСКИМ ДЕЙСТВИЕМ TNF-α
|
|
WO2010005570A2
(en)
*
|
2008-07-09 |
2010-01-14 |
Biogen Idec Ma Inc. |
Compositions comprising antibodies to lingo or fragments thereof
|
|
CA3153682A1
(en)
|
2008-11-17 |
2010-05-20 |
Veracyte, Inc. |
Methods and compositions of molecular profiling for disease diagnostics
|
|
FR2958293B1
(fr)
|
2010-04-01 |
2014-09-26 |
Centre Nat Rech Scient |
Outils pour l'identification de ligands de lingo-1,lingo-2, lingo-3 et lingo-4, et utilisations
|
|
MX381731B
(es)
|
2012-05-14 |
2025-03-13 |
Biogen Ma Inc |
Antagonistas de proteina que interactua con el receptor nogo 2 que contiene repeticion rica en leucina y dominio de inmunoglobulina (lingo-2) para el tratamiento de afecciones que involucran neuronas motoras.
|