JP4295357B2 - ネガティブホルモン活性および／または拮抗薬活性を有するレチノイド化合物の合成と使用 - Google Patents

ネガティブホルモン活性および／または拮抗薬活性を有するレチノイド化合物の合成と使用 Download PDF

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JP4295357B2
JP4295357B2 JP51125897A JP51125897A JP4295357B2 JP 4295357 B2 JP4295357 B2 JP 4295357B2 JP 51125897 A JP51125897 A JP 51125897A JP 51125897 A JP51125897 A JP 51125897A JP 4295357 B2 JP4295357 B2 JP 4295357B2
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JP2002504887A (ja
JP2002504887A5 (enExample
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クライン，エリオット・エス
ジョンソン，アラン・ティ
スタンデヴェン，アンドリュー・エム
ビアード，リチャード・エル
ジレット，サミュエル・ジェイ
デュオン，ティエン・ティ
ナグパル，スニル
ヴリゴンダ，ヴィディアサガー
テン，ミン
チャンドララトナ，ロシャンタ・エイ
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Allergan Inc
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    • C07C69/84—Esters of carboxylic acids having a carboxyl group bound to a carbon atom of a six-membered aromatic ring of monocyclic hydroxy carboxylic acids, the hydroxy groups and the carboxyl groups of which are bound to carbon atoms of a six-membered aromatic ring
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  • Epidemiology (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Pyrane Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Pyridine Compounds (AREA)
  • Heterocyclic Compounds Containing Sulfur Atoms (AREA)
  • Thiazole And Isothizaole Compounds (AREA)
  • Quinoline Compounds (AREA)
  • Furan Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
JP51125897A 1995-09-01 1996-08-23 ネガティブホルモン活性および／または拮抗薬活性を有するレチノイド化合物の合成と使用 Expired - Fee Related JP4295357B2 (ja)

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Application Number Priority Date Filing Date Title
US52277895A 1995-09-01 1995-09-01
US52277995A 1995-09-01 1995-09-01
US08/522,779 1995-09-01
US08/522,778 1995-09-01
US54264895A 1995-10-13 1995-10-13
US08/542,648 1995-10-13
US08/613,863 US5776699A (en) 1995-09-01 1996-03-11 Method of identifying negative hormone and/or antagonist activities
US08/613,863 1996-03-11
PCT/US1996/013779 WO1997009297A2 (en) 1995-09-01 1996-08-23 Synthesis and use of retinoid compounds having negative hormone and/or antagonist activities

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JP2008106449A Division JP2008280346A (ja) 1995-09-01 2008-04-16 ネガティブホルモン活性および／または拮抗薬活性を有するレチノイド化合物の合成と使用

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JP2002504887A5 JP2002504887A5 (enExample) 2004-09-24
JP4295357B2 true JP4295357B2 (ja) 2009-07-15

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KR (3) KR100447046B1 (enExample)
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Publication number Priority date Publication date Assignee Title
US7655699B1 (en) 1992-04-22 2010-02-02 Eisai Inc. Compounds having selective activity for retinoid X receptors, and means for modulation of processes mediated by retinoid X receptors
GB9222253D0 (en) * 1992-10-23 1992-12-09 Celltech Ltd Chemical compounds
GB9304920D0 (en) * 1993-03-10 1993-04-28 Celltech Ltd Chemical compounds
GB9304919D0 (en) * 1993-03-10 1993-04-28 Celltech Ltd Chemical compounds
EP0738268B1 (en) * 1993-12-22 2004-03-03 Celltech R&D Limited Trisubstituted phenyl derivatives, processes for their preparation and their use as phosphodiesterase (type iv) inhibitors
US6245774B1 (en) 1994-06-21 2001-06-12 Celltech Therapeutics Limited Tri-substituted phenyl or pyridine derivatives
US5958954A (en) * 1995-09-01 1999-09-28 Allergan Sales, Inc. Synthesis and use of retinoid compounds having negative hormone and/or antagonist activities
US6942980B1 (en) * 1995-09-01 2005-09-13 Allergan, Inc. Methods of identifying compounds having nuclear receptor negative hormone and/or antagonist activities
GB9523675D0 (en) * 1995-11-20 1996-01-24 Celltech Therapeutics Ltd Chemical compounds
GB9526243D0 (en) * 1995-12-21 1996-02-21 Celltech Therapeutics Ltd Chemical compounds
GB9526245D0 (en) * 1995-12-21 1996-02-21 Celltech Therapeutics Ltd Chemical compounds
US5877207A (en) * 1996-03-11 1999-03-02 Allergan Sales, Inc. Synthesis and use of retinoid compounds having negative hormone and/or antagonist activities
KR100485642B1 (ko) 1996-03-18 2005-09-30 에자이 가부시키가이샤 축합고리함유카르복실산유도체
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