JP4141384B2 - 試料処理装置及び試料処理方法 - Google Patents

試料処理装置及び試料処理方法 Download PDF

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Publication number
JP4141384B2
JP4141384B2 JP2003529944A JP2003529944A JP4141384B2 JP 4141384 B2 JP4141384 B2 JP 4141384B2 JP 2003529944 A JP2003529944 A JP 2003529944A JP 2003529944 A JP2003529944 A JP 2003529944A JP 4141384 B2 JP4141384 B2 JP 4141384B2
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Prior art keywords
liquid supply
separation column
nozzle
nucleic acid
supply channel
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Expired - Fee Related
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JP2003529944A
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Japanese (ja)
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JPWO2003025170A1 (ja
Inventor
義之 庄司
敏昭 横林
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Hitachi Ltd
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Hitachi Ltd
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    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N35/00Automatic analysis not limited to methods or materials provided for in any single one of groups G01N1/00 - G01N33/00; Handling materials therefor
    • G01N35/10Devices for transferring samples or any liquids to, in, or from, the analysis apparatus, e.g. suction devices, injection devices
    • G01N35/1004Cleaning sample transfer devices
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12MAPPARATUS FOR ENZYMOLOGY OR MICROBIOLOGY; APPARATUS FOR CULTURING MICROORGANISMS FOR PRODUCING BIOMASS, FOR GROWING CELLS OR FOR OBTAINING FERMENTATION OR METABOLIC PRODUCTS, i.e. BIOREACTORS OR FERMENTERS
    • C12M1/00Apparatus for enzymology or microbiology
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B01PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01LCHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L3/00Containers or dishes for laboratory use, e.g. laboratory glassware; Droppers
    • B01L3/02Burettes; Pipettes
    • B01L3/0275Interchangeable or disposable dispensing tips
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09Recombinant DNA-technology
    • C12N15/10Processes for the isolation, preparation or purification of DNA or RNA
    • C12N15/1003Extracting or separating nucleic acids from biological samples, e.g. pure separation or isolation methods; Conditions, buffers or apparatuses therefor
    • C12N15/1006Extracting or separating nucleic acids from biological samples, e.g. pure separation or isolation methods; Conditions, buffers or apparatuses therefor by means of a solid support carrier, e.g. particles, polymers
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N30/00Investigating or analysing materials by separation into components using adsorption, absorption or similar phenomena or using ion-exchange, e.g. chromatography or field flow fractionation
    • G01N30/02Column chromatography
    • G01N30/88Integrated analysis systems specially adapted therefor, not covered by a single one of the groups G01N30/04 - G01N30/86
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N30/00Investigating or analysing materials by separation into components using adsorption, absorption or similar phenomena or using ion-exchange, e.g. chromatography or field flow fractionation
    • G01N30/02Column chromatography
    • G01N30/88Integrated analysis systems specially adapted therefor, not covered by a single one of the groups G01N30/04 - G01N30/86
    • G01N2030/8809Integrated analysis systems specially adapted therefor, not covered by a single one of the groups G01N30/04 - G01N30/86 analysis specially adapted for the sample
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N30/00Investigating or analysing materials by separation into components using adsorption, absorption or similar phenomena or using ion-exchange, e.g. chromatography or field flow fractionation
    • G01N30/02Column chromatography
    • G01N30/88Integrated analysis systems specially adapted therefor, not covered by a single one of the groups G01N30/04 - G01N30/86
    • G01N2030/8809Integrated analysis systems specially adapted therefor, not covered by a single one of the groups G01N30/04 - G01N30/86 analysis specially adapted for the sample
    • G01N2030/8813Integrated analysis systems specially adapted therefor, not covered by a single one of the groups G01N30/04 - G01N30/86 analysis specially adapted for the sample biological materials
    • G01N2030/8827Integrated analysis systems specially adapted therefor, not covered by a single one of the groups G01N30/04 - G01N30/86 analysis specially adapted for the sample biological materials involving nucleic acids
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N30/00Investigating or analysing materials by separation into components using adsorption, absorption or similar phenomena or using ion-exchange, e.g. chromatography or field flow fractionation
    • G01N30/02Column chromatography
    • G01N30/88Integrated analysis systems specially adapted therefor, not covered by a single one of the groups G01N30/04 - G01N30/86
    • G01N2030/8809Integrated analysis systems specially adapted therefor, not covered by a single one of the groups G01N30/04 - G01N30/86 analysis specially adapted for the sample
    • G01N2030/8872Integrated analysis systems specially adapted therefor, not covered by a single one of the groups G01N30/04 - G01N30/86 analysis specially adapted for the sample impurities
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N30/00Investigating or analysing materials by separation into components using adsorption, absorption or similar phenomena or using ion-exchange, e.g. chromatography or field flow fractionation
    • G01N30/02Column chromatography
    • G01N30/26Conditioning of the fluid carrier; Flow patterns
    • G01N30/38Flow patterns
    • G01N30/46Flow patterns using more than one column
    • G01N30/466Flow patterns using more than one column with separation columns in parallel

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  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biochemistry (AREA)
  • Genetics & Genomics (AREA)
  • Biomedical Technology (AREA)
  • General Health & Medical Sciences (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • Biotechnology (AREA)
  • Organic Chemistry (AREA)
  • Physics & Mathematics (AREA)
  • Analytical Chemistry (AREA)
  • General Engineering & Computer Science (AREA)
  • Immunology (AREA)
  • General Physics & Mathematics (AREA)
  • Pathology (AREA)
  • Microbiology (AREA)
  • Clinical Laboratory Science (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Crystallography & Structural Chemistry (AREA)
  • Biophysics (AREA)
  • Molecular Biology (AREA)
  • Plant Pathology (AREA)
  • Sustainable Development (AREA)
  • Medicinal Chemistry (AREA)
  • Apparatus Associated With Microorganisms And Enzymes (AREA)
  • Automatic Analysis And Handling Materials Therefor (AREA)
  • Sampling And Sample Adjustment (AREA)
  • Physical Or Chemical Processes And Apparatus (AREA)
JP2003529944A 2001-09-17 2001-09-17 試料処理装置及び試料処理方法 Expired - Fee Related JP4141384B2 (ja)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
PCT/JP2001/008062 WO2003025170A1 (fr) 2001-09-17 2001-09-17 Dispositif et procede de traitement d'echantillons

Publications (2)

Publication Number Publication Date
JPWO2003025170A1 JPWO2003025170A1 (ja) 2004-12-24
JP4141384B2 true JP4141384B2 (ja) 2008-08-27

Family

ID=11737731

Family Applications (1)

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JP2003529944A Expired - Fee Related JP4141384B2 (ja) 2001-09-17 2001-09-17 試料処理装置及び試料処理方法

Country Status (6)

Country Link
US (1) US7025876B2 (fr)
EP (1) EP1431390A4 (fr)
JP (1) JP4141384B2 (fr)
KR (1) KR100632893B1 (fr)
CN (1) CN1541268A (fr)
WO (1) WO2003025170A1 (fr)

Families Citing this family (16)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP1693670A4 (fr) * 2003-12-04 2008-06-11 Olympus Corp Recipient de reaction et dispositif de reaction le contenant, dispositif de detection et procede pour produire ledit recipient de reaction
FR2867089B1 (fr) * 2004-03-03 2006-06-09 Bionisis Sa Installation de separation de composants dans plusieurs voies paralleles
JP2006006258A (ja) * 2004-06-29 2006-01-12 Fuji Photo Film Co Ltd 核酸の核酸抽出方法および核酸抽出装置
WO2005111210A1 (fr) * 2004-05-18 2005-11-24 Fujifilm Corporation Procede d'extraction d'acide nucleique et appareil d'extraction d'acide nucleique
JP4328788B2 (ja) * 2005-10-04 2009-09-09 キヤノン株式会社 核酸試料検査装置
JP4328787B2 (ja) 2005-10-04 2009-09-09 キヤノン株式会社 核酸試料検査装置
US7713232B2 (en) * 2005-11-04 2010-05-11 Medrad, Inc. System for washing and processing of cells for delivery thereof to tissue
JP5530609B2 (ja) * 2008-09-05 2014-06-25 株式会社日立ハイテクノロジーズ 前処理装置及びそれを備えた質量分析装置
JP4811797B2 (ja) * 2010-01-26 2011-11-09 株式会社日立プラントテクノロジー 発光測定装置の配管洗浄方法、発光測定装置の配管洗浄機構
CN101806810B (zh) * 2010-04-29 2013-06-05 山东博科生物产业有限公司 多试剂针生化分析仪
FR3009622B1 (fr) * 2013-08-09 2015-08-07 Novacyt Procede et dispositif de lavage d'un dispositif de pipetage-distribution
CN103698187B (zh) * 2013-12-27 2016-03-30 天津口岸检测分析开发服务有限公司 一种标准溶液自动配置仪及自动分配方法
WO2016009764A1 (fr) * 2014-07-18 2016-01-21 株式会社 日立ハイテクノロジーズ Procédé d'agitation de liquide
KR101971635B1 (ko) * 2017-07-24 2019-04-24 한국과학기술원 유전자 판별칩용 정량주입장치 및 이를 이용한 유전자 정량주입방법
JP7260960B2 (ja) * 2018-03-29 2023-04-19 シスメックス株式会社 検体前処理装置、ロボットアームおよび検体前処理方法
CN116672760B (zh) * 2023-08-03 2023-10-20 成都百泉生物医药科技有限公司 一种固相萃取仪

Family Cites Families (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS5830216Y2 (ja) * 1979-12-26 1983-07-02 日本電子株式会社 二重ノズルカラム栓
JPS5697744A (en) 1980-01-08 1981-08-06 Matsushita Electric Ind Co Ltd Control system for room air heater using kerosin
JPH07119747B2 (ja) 1987-05-14 1995-12-20 積水化学工業株式会社 カラム
JPH0560736A (ja) 1991-09-02 1993-03-12 Jasco Corp Hplc用オートサンプラーのニードルの洗浄方法
JPH0830701B2 (ja) 1992-12-30 1996-03-27 株式会社島津製作所 固相抽出前処理装置
GB9314249D0 (en) * 1993-07-09 1993-08-18 Proofname Ltd Purification method and apparatus
DE19806780C1 (de) * 1998-02-18 1999-07-01 November Ag Molekulare Medizin Vorrichtung zur Isolierung und Aufreinigung von Nukleinsäuren
JPH11248695A (ja) 1998-03-05 1999-09-17 Japan Nuclear Fuel Co Ltd(Jnf) イオン交換分離用カラム装置
JPH11266864A (ja) 1998-03-19 1999-10-05 Hitachi Ltd 核酸の精製方法および精製用装置

Also Published As

Publication number Publication date
JPWO2003025170A1 (ja) 2004-12-24
KR100632893B1 (ko) 2006-10-12
US20040181050A1 (en) 2004-09-16
CN1541268A (zh) 2004-10-27
KR20040035718A (ko) 2004-04-29
EP1431390A1 (fr) 2004-06-23
WO2003025170A1 (fr) 2003-03-27
EP1431390A4 (fr) 2006-06-21
US7025876B2 (en) 2006-04-11

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