JP3411036B2 - リグナン系化合物の製造方法 - Google Patents

リグナン系化合物の製造方法

Info

Publication number
JP3411036B2
JP3411036B2 JP52298294A JP52298294A JP3411036B2 JP 3411036 B2 JP3411036 B2 JP 3411036B2 JP 52298294 A JP52298294 A JP 52298294A JP 52298294 A JP52298294 A JP 52298294A JP 3411036 B2 JP3411036 B2 JP 3411036B2
Authority
JP
Japan
Prior art keywords
compound
reaction
synthesis
group
reference example
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Fee Related
Application number
JP52298294A
Other languages
English (en)
Japanese (ja)
Other versions
JPWO1994024087A1 (ja
Inventor
森　　幸雄
正三 武智
士郎 木田
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Shionogi and Co Ltd
Original Assignee
Shionogi and Co Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Shionogi and Co Ltd filed Critical Shionogi and Co Ltd
Publication of JPWO1994024087A1 publication Critical patent/JPWO1994024087A1/ja
Application granted granted Critical
Publication of JP3411036B2 publication Critical patent/JP3411036B2/ja
Anticipated expiration legal-status Critical
Expired - Fee Related legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C69/00—Esters of carboxylic acids; Esters of carbonic or haloformic acids
    • C07C69/76—Esters of carboxylic acids having a carboxyl group bound to a carbon atom of a six-membered aromatic ring
    • C07C69/94—Esters of carboxylic acids having a carboxyl group bound to a carbon atom of a six-membered aromatic ring of polycyclic hydroxy carboxylic acids, the hydroxy groups and the carboxyl groups of which are bound to carbon atoms of six-membered aromatic rings

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Steroid Compounds (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
  • Furan Compounds (AREA)
JP52298294A 1993-04-16 1994-04-12 リグナン系化合物の製造方法 Expired - Fee Related JP3411036B2 (ja)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
JP8994493 1993-04-16
JP5-89944 1993-04-16
PCT/JP1994/000612 WO1994024087A1 (fr) 1993-04-16 1994-04-12 Procede pour produire un compose de lignane

Publications (2)

Publication Number Publication Date
JPWO1994024087A1 JPWO1994024087A1 (ja) 1995-05-11
JP3411036B2 true JP3411036B2 (ja) 2003-05-26

Family

ID=13984820

Family Applications (1)

Application Number Title Priority Date Filing Date
JP52298294A Expired - Fee Related JP3411036B2 (ja) 1993-04-16 1994-04-12 リグナン系化合物の製造方法

Country Status (13)

Country Link
US (1) US5488134A (OSRAM)
EP (1) EP0646570B1 (OSRAM)
JP (1) JP3411036B2 (OSRAM)
KR (1) KR100277242B1 (OSRAM)
CN (1) CN1046937C (OSRAM)
AT (1) ATE167662T1 (OSRAM)
AU (1) AU666819B2 (OSRAM)
CA (1) CA2138264C (OSRAM)
DE (1) DE69411243T2 (OSRAM)
DK (1) DK0646570T3 (OSRAM)
ES (1) ES2119190T3 (OSRAM)
TW (1) TW255886B (OSRAM)
WO (1) WO1994024087A1 (OSRAM)

Families Citing this family (24)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA2121060C (en) * 1993-04-16 2004-04-06 Sachio Mori Preparation of lignan analogues
US6642268B2 (en) 1994-09-13 2003-11-04 G.D. Searle & Co. Combination therapy employing ileal bile acid transport inhibiting benzothipines and HMG Co-A reductase inhibitors
US6262277B1 (en) 1994-09-13 2001-07-17 G.D. Searle And Company Intermediates and processes for the preparation of benzothiepines having activity as inhibitors of ileal bile acid transport and taurocholate uptake
US6268392B1 (en) 1994-09-13 2001-07-31 G. D. Searle & Co. Combination therapy employing ileal bile acid transport inhibiting benzothiepines and HMG Co-A reductase inhibitors
KR100376281B1 (ko) * 1995-12-26 2003-09-26 에스케이케미칼주식회사 리그난의 제조방법
TW510902B (en) 1997-09-29 2002-11-21 Meiji Seika Kaisha Tricyclic triazolobenzazepine derivatives, process for producing the same, and antiallergic agents
ATE241386T1 (de) 1998-12-23 2003-06-15 Searle Llc Kombinationen von ileumgallensäuretransports inhibitoren und cholesteryl ester transfer protein inhibitoren
EP1340510A1 (en) 1998-12-23 2003-09-03 G.D. Searle LLC. Combinations of cholesteryl ester transfer protein inhibitors and bile acid sequestering agents for cardiovascular indications
PT1140184E (pt) 1998-12-23 2003-10-31 Searle Llc Combinacoes de inibidores de proteina de transferencia de ester de colesterilo com derivados de acido nicotinico para indicacoes cardiovasculares
US6462091B1 (en) 1998-12-23 2002-10-08 G.D. Searle & Co. Combinations of cholesteryl ester transfer protein inhibitors and HMG coA reductase inhibitors for cardiovascular indications
EA004231B1 (ru) 1998-12-23 2004-02-26 Джи.Ди.Сирл Ллс Сочетание ингибиторов белка, переносящего эфир холестерила, и производных фибриновой кислоты для сердечно-сосудистых показаний
CA2356607A1 (en) 1998-12-23 2000-07-06 G.D. Searle Llc Combinations of ileal bile acid transport inhibitors and fibric acid derivatives for cardiovascular indications
CA2356156A1 (en) 1998-12-23 2000-07-06 G.D. Searle Llc Combinations of ileal bile acid transport inhibitors and bile acid sequestring agents for cardiovascular indications
HK1052183A1 (zh) 2000-03-10 2003-09-05 Pharmacia Corporation 制造tetrahydrobenzothiepines的方法
AU2001247331A1 (en) * 2000-03-10 2001-09-24 Pharmacia Corporation Combination therapy for the prophylaxis and treatment of hyperlipidemic conditions and disorders
BR0213501A (pt) 2001-11-02 2004-08-24 Searle Llc Compostos de benzotiepina mono- e di-fluorada como inibidores de transporte de ácido biliar co-dependente de sódio apical (asbt) e captação de taurocolato
AU2003207431A1 (en) 2002-01-17 2003-09-02 Pharmacia Corporation Novel alkyl/aryl hydroxy or keto thiepines.
GB0307918D0 (en) 2003-04-05 2003-05-14 Astrazeneca Ab Therapeutic use
EP2995317A1 (en) 2010-05-26 2016-03-16 Satiogen Pharmaceuticals, Inc. Bile acid recycling inhibitors and satiogens for treatment of diabetes, obesity, and inflammatory gastrointestinal conditions
KR102051031B1 (ko) 2011-10-28 2019-12-02 루메나 파마수티컬즈, 인코포레이티드 고담혈증 및 담즙 정체성 간 질환 치료용 담즙산 재순환 억제제
EP2771003B1 (en) 2011-10-28 2017-04-19 Lumena Pharmaceuticals LLC Bile acid recycling inhibitors for treatment of pediatric cholestatic liver diseases
MX2015013193A (es) 2013-03-15 2016-04-15 Lumena Pharmaceuticals Inc Inhibidores del reciclaje de acidos biliares para el tratamiento de colangitis esclerosante primaria y enfermedad inflamatoria intestinal.
CA2907214A1 (en) 2013-03-15 2014-09-18 Lumena Pharmaceuticals, Inc. Bile acid recycling inhibitors for treatment of barrett's esophagus and gastroesophageal reflux disease
WO2020167981A1 (en) 2019-02-12 2020-08-20 Mirum Pharmaceuticals, Inc. Methods for increasing growth in pediatric subjects having cholestatic liver disease

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPH0372422A (ja) * 1989-05-16 1991-03-27 Tanabe Seiyaku Co Ltd 抗脂血剤
JPH03157351A (ja) * 1989-11-13 1991-07-05 Tanabe Seiyaku Co Ltd ナフタレン誘導体及びその製法
ATE175954T1 (de) * 1991-10-17 1999-02-15 Shionogi & Co Verfahren zum herstellen von lignin-analoga und ausgangsprodukte dafür

Also Published As

Publication number Publication date
CN1109685A (zh) 1995-10-04
EP0646570A1 (en) 1995-04-05
CN1046937C (zh) 1999-12-01
ATE167662T1 (de) 1998-07-15
KR950701902A (ko) 1995-05-17
DK0646570T3 (da) 1998-10-26
TW255886B (OSRAM) 1995-09-01
US5488134A (en) 1996-01-30
ES2119190T3 (es) 1998-10-01
WO1994024087A1 (fr) 1994-10-27
DE69411243T2 (de) 1998-11-19
EP0646570A4 (en) 1995-08-09
CA2138264C (en) 2004-04-06
CA2138264A1 (en) 1994-10-27
EP0646570B1 (en) 1998-06-24
AU666819B2 (en) 1996-02-22
DE69411243D1 (de) 1998-07-30
KR100277242B1 (ko) 2001-02-01
AU6437994A (en) 1994-11-08

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