JP2025507915A5 - - Google Patents
Info
- Publication number
- JP2025507915A5 JP2025507915A5 JP2024552219A JP2024552219A JP2025507915A5 JP 2025507915 A5 JP2025507915 A5 JP 2025507915A5 JP 2024552219 A JP2024552219 A JP 2024552219A JP 2024552219 A JP2024552219 A JP 2024552219A JP 2025507915 A5 JP2025507915 A5 JP 2025507915A5
- Authority
- JP
- Japan
- Prior art keywords
- heterocycloalkyl
- cycloalkyl
- alkyl
- heteroaryl
- aryl
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
Applications Claiming Priority (9)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN2022078655 | 2022-03-01 | ||
| CNPCT/CN2022/078655 | 2022-03-01 | ||
| CNPCT/CN2022/091215 | 2022-05-06 | ||
| CN2022091215 | 2022-05-06 | ||
| CNPCT/CN2022/128282 | 2022-10-28 | ||
| CN2022128282 | 2022-10-28 | ||
| CN2023071962 | 2023-01-12 | ||
| CNPCT/CN2023/071962 | 2023-01-12 | ||
| PCT/CN2023/078973 WO2023165509A1 (en) | 2022-03-01 | 2023-03-01 | Diacylglycerol kinase (dgk) alpha inhibitors and uses thereof |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JP2025507915A JP2025507915A (ja) | 2025-03-21 |
| JP2025507915A5 true JP2025507915A5 (https=) | 2026-03-09 |
Family
ID=87883015
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2024552219A Pending JP2025507915A (ja) | 2022-03-01 | 2023-03-01 | ジアシルグリセロールキナーゼ（ＤＧＫ）α阻害剤及びその使用 |
Country Status (7)
| Country | Link |
|---|---|
| US (1) | US20250214990A1 (https=) |
| EP (1) | EP4486745A4 (https=) |
| JP (1) | JP2025507915A (https=) |
| CN (1) | CN118829642A (https=) |
| AR (1) | AR128668A1 (https=) |
| TW (1) | TW202342478A (https=) |
| WO (1) | WO2023165509A1 (https=) |
Families Citing this family (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP4486741A4 (en) | 2022-03-01 | 2026-04-08 | Insilico Medicine Ip Ltd | Diacylglycerol Kinase (DGK) Alpha Inhibitors and Their Uses |
| EP4661869A1 (en) | 2023-02-06 | 2025-12-17 | Bayer Aktiengesellschaft | Combinations of dgk (diacylglycerol kinase) inhibitors and immune checkpoint inhibitors and modulators |
| WO2025051110A1 (en) * | 2023-09-04 | 2025-03-13 | Insilico Medicine Ip Limited | Combinations treatments of diacylglycerol kinase (dgk) alpha inhibitors and other therapies |
Family Cites Families (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2011075747A1 (en) * | 2009-12-18 | 2011-06-23 | Glaxosmithkline Llc | Therapeutic compounds |
| KR102767739B1 (ko) * | 2018-06-27 | 2025-02-12 | 브리스톨-마이어스 스큅 컴퍼니 | T 세포 활성화제로서 유용한 치환된 나프티리디논 화합물 |
| US20230062100A1 (en) * | 2019-11-28 | 2023-03-02 | Bayer Aktiengesellschaft | Substituted aminoquinolones as dgkalpha inhibitors for immune activation |
| BR112022012179A2 (pt) * | 2019-12-23 | 2022-09-06 | Bristol Myers Squibb Co | Compostos de quinazolina substituída úteis como ativadores de célula t |
| IL294032A (en) * | 2019-12-24 | 2022-08-01 | Carna Biosciences Inc | Compounds that regulate diacylglycerol kinase |
| MX2023014762A (es) * | 2021-06-23 | 2024-01-15 | Gilead Sciences Inc | Compuestos moduladores de diacilglicerol quinasa. |
-
2023
- 2023-03-01 JP JP2024552219A patent/JP2025507915A/ja active Pending
- 2023-03-01 EP EP23762907.6A patent/EP4486745A4/en active Pending
- 2023-03-01 CN CN202380024556.1A patent/CN118829642A/zh active Pending
- 2023-03-01 WO PCT/CN2023/078973 patent/WO2023165509A1/en not_active Ceased
- 2023-03-01 AR ARP230100508A patent/AR128668A1/es unknown
- 2023-03-01 US US18/841,639 patent/US20250214990A1/en active Pending
- 2023-03-01 TW TW112107273A patent/TW202342478A/zh unknown