JP2020530487A5 - - Google Patents
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- JP2020530487A5 JP2020530487A5 JP2020529113A JP2020529113A JP2020530487A5 JP 2020530487 A5 JP2020530487 A5 JP 2020530487A5 JP 2020529113 A JP2020529113 A JP 2020529113A JP 2020529113 A JP2020529113 A JP 2020529113A JP 2020530487 A5 JP2020530487 A5 JP 2020530487A5
- Authority
- JP
- Japan
- Prior art keywords
- pharmaceutically acceptable
- solvate
- substituted
- acceptable salt
- unsubstituted
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
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- 150000001875 compounds Chemical class 0.000 claims 21
- 150000003839 salts Chemical class 0.000 claims 18
- 239000012453 solvate Substances 0.000 claims 18
- 125000004093 cyano group Chemical group *C#N 0.000 claims 3
- 125000000753 cycloalkyl group Chemical group 0.000 claims 3
- 229910052736 halogen Inorganic materials 0.000 claims 3
- 229910052739 hydrogen Inorganic materials 0.000 claims 3
- 125000005913 (C3-C6) cycloalkyl group Chemical group 0.000 claims 2
- 125000000217 alkyl group Chemical group 0.000 claims 2
- 125000001559 cyclopropyl group Chemical group [H]C1([H])C([H])([H])C1([H])* 0.000 claims 2
- 150000002367 halogens Chemical group 0.000 claims 2
- 125000000592 heterocycloalkyl group Chemical group 0.000 claims 2
- 125000002887 hydroxy group Chemical group [H]O* 0.000 claims 2
- 125000003545 alkoxy group Chemical group 0.000 claims 1
- 229910052799 carbon Inorganic materials 0.000 claims 1
- 125000001995 cyclobutyl group Chemical group [H]C1([H])C([H])([H])C([H])(*)C1([H])[H] 0.000 claims 1
- 125000000113 cyclohexyl group Chemical group [H]C1([H])C([H])([H])C([H])([H])C([H])(*)C([H])([H])C1([H])[H] 0.000 claims 1
- 125000001511 cyclopentyl group Chemical group [H]C1([H])C([H])([H])C([H])([H])C([H])(*)C1([H])[H] 0.000 claims 1
- 201000010099 disease Diseases 0.000 claims 1
- 208000037265 diseases, disorders, signs and symptoms Diseases 0.000 claims 1
- 239000003814 drug Substances 0.000 claims 1
- 239000003937 drug carrier Substances 0.000 claims 1
- 125000005843 halogen group Chemical group 0.000 claims 1
- 125000004404 heteroalkyl group Chemical group 0.000 claims 1
- 125000005842 heteroatom Chemical group 0.000 claims 1
- -1 hydroxy, amino, methoxy Chemical group 0.000 claims 1
- 229910052760 oxygen Inorganic materials 0.000 claims 1
- 239000008194 pharmaceutical composition Substances 0.000 claims 1
- 239000000546 pharmaceutical excipient Substances 0.000 claims 1
- 125000006413 ring segment Chemical group 0.000 claims 1
- 125000001424 substituent group Chemical group 0.000 claims 1
- 229910052717 sulfur Inorganic materials 0.000 claims 1
Applications Claiming Priority (7)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201762541202P | 2017-08-04 | 2017-08-04 | |
| US62/541,202 | 2017-08-04 | ||
| US201762562927P | 2017-09-25 | 2017-09-25 | |
| US201762562948P | 2017-09-25 | 2017-09-25 | |
| US62/562,948 | 2017-09-25 | ||
| US62/562,927 | 2017-09-25 | ||
| PCT/US2018/045282 WO2019028440A1 (en) | 2017-08-04 | 2018-08-03 | METHODS AND COMPOSITIONS FOR MODULATING SPLICING |
Related Child Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2020078335A Division JP7135026B2 (ja) | 2017-08-04 | 2020-04-27 | スプライシングをモジュレートする方法および組成物 |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2020530487A JP2020530487A (ja) | 2020-10-22 |
| JP2020530487A5 true JP2020530487A5 (https=) | 2021-09-16 |
| JP7312749B2 JP7312749B2 (ja) | 2023-07-21 |
Family
ID=65233135
Family Applications (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2020529113A Active JP7312749B2 (ja) | 2017-08-04 | 2018-08-03 | スプライシングをモジュレートする方法および組成物 |
| JP2020078335A Active JP7135026B2 (ja) | 2017-08-04 | 2020-04-27 | スプライシングをモジュレートする方法および組成物 |
Family Applications After (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2020078335A Active JP7135026B2 (ja) | 2017-08-04 | 2020-04-27 | スプライシングをモジュレートする方法および組成物 |
Country Status (15)
| Country | Link |
|---|---|
| US (8) | US11162101B2 (https=) |
| EP (2) | EP3661509A4 (https=) |
| JP (2) | JP7312749B2 (https=) |
| KR (2) | KR102636383B1 (https=) |
| CN (2) | CN111194215B (https=) |
| AU (2) | AU2018309187C1 (https=) |
| CA (1) | CA3072205A1 (https=) |
| GB (2) | GB2587457B (https=) |
| IL (2) | IL273741B (https=) |
| MX (2) | MX2020001425A (https=) |
| MY (1) | MY201938A (https=) |
| RU (1) | RU2020105929A (https=) |
| SG (2) | SG11202000980QA (https=) |
| WO (1) | WO2019028440A1 (https=) |
| ZA (2) | ZA202000695B (https=) |
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