|
BR112014015197A8
(pt)
|
2011-12-21 |
2017-06-13 |
Novira Therapeutics Inc |
agentes antivirais de hepatite b
|
|
KR102271574B1
(ko)
|
2012-08-28 |
2021-07-01 |
얀센 사이언시즈 아일랜드 언리미티드 컴퍼니 |
설파모일-아릴아미드 및 b형 간염 치료제로서의 그 용도
|
|
BR112015015584A2
(pt)
*
|
2012-12-27 |
2017-12-12 |
Baruch S Blumberg Inst |
novos agentes antivirais contra infecção por hbv
|
|
WO2014131847A1
(en)
|
2013-02-28 |
2014-09-04 |
Janssen R&D Ireland |
Sulfamoyl-arylamides and the use thereof as medicaments for the treatment of hepatitis b
|
|
MX353412B
(es)
|
2013-04-03 |
2018-01-10 |
Janssen Sciences Ireland Uc |
Derivados de n-fenil-carboxamida y su uso como medicamentos para el tratamiento de la hepatitis b.
|
|
TWI733288B
(zh)
|
2013-05-17 |
2021-07-11 |
愛爾蘭商健生科學愛爾蘭無限公司 |
胺磺醯基吡咯醯胺衍生物及其作為用於治療b型肝炎藥物的用途
|
|
HRP20180791T1
(hr)
|
2013-07-25 |
2018-09-07 |
Janssen Sciences Ireland Uc |
Glioksamid supstituirani derivati pirolamida i njihova uporaba kao lijekova za liječenje hepatitisa b
|
|
CA2923712C
(en)
|
2013-10-23 |
2021-11-02 |
Janssen Sciences Ireland Uc |
Carboxamide derivatives and the use thereof as medicaments for the treatment of hepatitis b
|
|
US10392349B2
(en)
|
2014-01-16 |
2019-08-27 |
Novira Therapeutics, Inc. |
Azepane derivatives and methods of treating hepatitis B infections
|
|
US9169212B2
(en)
|
2014-01-16 |
2015-10-27 |
Novira Therapeutics, Inc. |
Azepane derivatives and methods of treating hepatitis B infections
|
|
CA2936947A1
(en)
*
|
2014-02-05 |
2015-08-13 |
Novira Therapeutics, Inc. |
Combination therapy for treatment of hbv infections
|
|
TW201620893A
(zh)
|
2014-02-06 |
2016-06-16 |
健生科學愛爾蘭無限公司 |
磺醯胺基吡咯醯胺衍生物及其用作治療b型肝炎之醫藥品的用途
|
|
ES2748029T3
(es)
|
2014-03-13 |
2020-03-12 |
Univ Indiana Res & Tech Corp |
Moduladores alostéricos de proteína núcleo de hepatitis B
|
|
US9400280B2
(en)
|
2014-03-27 |
2016-07-26 |
Novira Therapeutics, Inc. |
Piperidine derivatives and methods of treating hepatitis B infections
|
|
CA2948580A1
(en)
*
|
2014-05-09 |
2015-11-12 |
Adam Zlotnick |
Methods and compositions for treating hepatitis b virus infections
|
|
CN107406378A
(zh)
*
|
2014-12-02 |
2017-11-28 |
诺维拉治疗公司 |
用于hbv治疗的硫化烷基化合物和吡啶类反式磺酰胺化合物
|
|
US9597332B2
(en)
|
2014-12-02 |
2017-03-21 |
Novira Therapeutics, Inc. |
Sulfide alkyl compounds for HBV treatment
|
|
MA41140A
(fr)
*
|
2014-12-12 |
2017-10-17 |
Cancer Research Tech Ltd |
Dérivés de 2,4-dioxo-quinazoline-6-sulfonamide en tant qu'inhibiteurs de la parg
|
|
MA41179A
(fr)
|
2014-12-19 |
2017-10-24 |
Cancer Research Tech Ltd |
Composés inhibiteurs de parg
|
|
US9765050B2
(en)
|
2014-12-30 |
2017-09-19 |
Novira Therapeutics, Inc. |
Pyridyl reverse sulfonamides for HBV treatment
|
|
CN107108610B
(zh)
|
2014-12-30 |
2019-06-04 |
豪夫迈·罗氏有限公司 |
用于治疗和预防肝炎b病毒感染的新的四氢吡啶并嘧啶和四氢吡啶并吡啶化合物
|
|
JP2018510159A
(ja)
*
|
2015-03-19 |
2018-04-12 |
ノヴィラ・セラピューティクス・インコーポレイテッド |
アゾカン及びアゾナン誘導体及びb型肝炎感染症の治療法
|
|
US10442788B2
(en)
|
2015-04-01 |
2019-10-15 |
Enanta Pharmaceuticals, Inc. |
Hepatitis B antiviral agents
|
|
WO2016177655A1
(en)
*
|
2015-05-04 |
2016-11-10 |
F. Hoffmann-La Roche Ag |
Tetrahydropyridopyrimidines and tetrahydropyridopyridines as inhibitors of hbsag (hbv surface antigen) and hbv dna production for the treatment of hepatitis b virus infections
|
|
WO2016183266A1
(en)
|
2015-05-13 |
2016-11-17 |
Enanta Pharmaceuticals, Inc. |
Ehpatitis b antiviral agents
|
|
US10875876B2
(en)
|
2015-07-02 |
2020-12-29 |
Janssen Sciences Ireland Uc |
Cyclized sulfamoylarylamide derivatives and the use thereof as medicaments for the treatment of hepatitis B
|
|
US10179131B2
(en)
|
2015-07-13 |
2019-01-15 |
Enanta Pharmaceuticals, Inc. |
Hepatitis B antiviral agents
|
|
TWI721016B
(zh)
|
2015-09-15 |
2021-03-11 |
美商艾森伯利生物科學公司 |
B型肝炎核心蛋白質調節劑
|
|
TW201718496A
(zh)
*
|
2015-09-29 |
2017-06-01 |
諾維拉治療公司 |
B型肝炎抗病毒劑之晶型
|
|
KR102398439B1
(ko)
|
2016-03-07 |
2022-05-16 |
이난타 파마슈티칼스, 인코포레이티드 |
B형 간염 항바이러스제
|
|
AU2017248828A1
(en)
|
2016-04-15 |
2018-11-01 |
Janssen Sciences Ireland Uc |
Combinations and methods comprising a capsid assembly inhibitor
|
|
US11124490B2
(en)
*
|
2016-06-03 |
2021-09-21 |
University Of Tennessee Research Foundation |
Autotaxin inhibitors
|
|
CA3028228A1
(en)
|
2016-06-10 |
2017-12-14 |
Enanta Pharmaceuticals, Inc. |
Hepatitis b antiviral agents
|
|
EP3500294A4
(en)
|
2016-08-22 |
2020-07-29 |
Arbutus Biopharma Corporation |
ANTI-PD-1 ANTIBODIES, OR THEIR FRAGMENTS, FOR THE TREATMENT OF HEPATITIS B
|
|
JOP20190024A1
(ar)
|
2016-08-26 |
2019-02-19 |
Gilead Sciences Inc |
مركبات بيروليزين بها استبدال واستخداماتها
|
|
WO2018052967A1
(en)
*
|
2016-09-13 |
2018-03-22 |
Arbutus Biopharma, Inc. |
Substituted chromane-8-carboxamide compounds and analogues thereof, and methods using same
|
|
AU2017326356A1
(en)
|
2016-09-15 |
2019-04-11 |
Assembly Biosciences, Inc. |
Hepatitis B core protein modulators
|
|
SG11201902944TA
(en)
|
2016-11-07 |
2019-05-30 |
Arbutus Biopharma Corp |
Substituted pyridinone-containing tricyclic compounds, and methods using same
|
|
EA202190306A1
(ru)
*
|
2016-11-11 |
2021-08-17 |
Новира Терапьютикс, Инк. |
Комбинации и способы, включающие ингибитор сборки капсида
|
|
US10654837B2
(en)
|
2017-02-07 |
2020-05-19 |
Janssen Pharmaceutica Nv |
Sulphamoylaryl derivatives and use thereof as medicaments for the treatment of liver fibrosis
|
|
RU2650610C1
(ru)
|
2017-02-28 |
2018-04-16 |
Васильевич Иващенко Александр |
Противовирусная композиция и способ ее применения
|
|
CA3055194A1
(en)
|
2017-03-02 |
2018-09-07 |
Assembly Biosciences, Inc. |
Cyclic sulfamide compounds and methods of using same
|
|
MA49014A
(fr)
|
2017-03-21 |
2020-02-05 |
Arbutus Biopharma Corp |
Dihydroindène-4-carboxamides substitués, leurs analogues et procédés d'utilisation correspondant
|
|
AU2018266911C1
(en)
|
2017-05-12 |
2022-10-20 |
Enanta Pharmaceuticals, Inc. |
Apoptosis signal-regulating kinase 1 inhibitors and methods of use thereof
|
|
AU2018291688B2
(en)
|
2017-06-27 |
2022-02-03 |
Janssen Pharmaceutica Nv |
Heteroaryldihydropyrimidine derivatives and methods of treating hepatitis B infections
|
|
US10513515B2
(en)
|
2017-08-25 |
2019-12-24 |
Biotheryx, Inc. |
Ether compounds and uses thereof
|
|
US10597382B2
(en)
|
2017-08-28 |
2020-03-24 |
Enanta Pharmaceuticals, Inc. |
Tetrazole containing apoptosis signal-regulating kinase 1 inhibitors and methods of use thereof
|
|
SG11202001685TA
(en)
|
2017-08-28 |
2020-03-30 |
Enanta Pharm Inc |
Hepatitis b antiviral agents
|
|
TW201912153A
(zh)
*
|
2017-08-30 |
2019-04-01 |
加拿大商愛彼特生物製藥公司 |
用於治療b型肝炎的化合物、醫藥組合物及方法
|
|
WO2019113175A1
(en)
|
2017-12-06 |
2019-06-13 |
Enanta Pharmaceuticals, Inc. |
Hepatitis b antiviral agents
|
|
WO2019113173A1
(en)
|
2017-12-06 |
2019-06-13 |
Enanta Pharmaceuticals, Inc. |
Hepatitis b antiviral agents
|
|
US11058678B2
(en)
|
2018-01-22 |
2021-07-13 |
Enanta Pharmaceuticals, Inc. |
Substituted heterocycles as antiviral agents
|
|
JP7050165B2
(ja)
|
2018-02-26 |
2022-04-07 |
ギリアード サイエンシーズ, インコーポレイテッド |
Hbv複製阻害剤としての置換ピロリジン化合物
|
|
MX2020009531A
(es)
|
2018-03-14 |
2020-10-05 |
Janssen Sciences Ireland Unlimited Co |
Regimen posologico del modulador del ensamblaje de la capside.
|
|
WO2019191166A1
(en)
|
2018-03-29 |
2019-10-03 |
Enanta Pharmaceuticals, Inc. |
Hepatitis b antiviral agents
|
|
WO2019206072A1
(zh)
*
|
2018-04-24 |
2019-10-31 |
浙江海正药业股份有限公司 |
磺酰胺芳基甲酰胺衍生物及其制备方法和用途
|
|
WO2019213239A1
(en)
*
|
2018-05-02 |
2019-11-07 |
Enanta Pharmaceuticals Inc. |
Apoptosis signal-regulating kinase 1 inhibitors and methods of use thereof
|
|
ES3004523T3
(en)
|
2018-05-02 |
2025-03-12 |
Enanta Pharm Inc |
Tetrazole containing apoptosis signal-regulating kinase 1 inhibitors and methods of use thereof
|
|
EP3597637A1
(en)
*
|
2018-07-19 |
2020-01-22 |
Irbm S.P.A. |
Inhibitors of hepatitis b virus
|
|
EP3597653A1
(en)
|
2018-07-19 |
2020-01-22 |
Irbm S.P.A. |
Cyclic inhibitors of hepatitis b virus
|
|
CA3106239A1
(en)
|
2018-07-27 |
2020-01-30 |
Biotheryx, Inc. |
Bifunctional compounds as cdk modulators
|
|
TWI826492B
(zh)
|
2018-07-27 |
2023-12-21 |
加拿大商愛彼特生物製藥公司 |
經取代四氫環戊[c]吡咯、經取代二氫吡咯,其類似物及使用其之方法
|
|
US11053235B2
(en)
|
2018-08-09 |
2021-07-06 |
Janssen Sciences Ireland Unlimited Company |
Substituted 1,4-dihydropyrimidines for the treatment of HBV infection or HBV-induced diseases
|
|
EP3608326A1
(en)
|
2018-08-10 |
2020-02-12 |
Irbm S.P.A. |
Tricyclic inhibitors of hepatitis b virus
|
|
WO2020041417A1
(en)
|
2018-08-22 |
2020-02-27 |
Enanta Pharmaceuticals, Inc. |
Cycloalkyl-containing apoptosis signal-regulating kinase 1 inhibitors and methods of use thereof
|
|
JP2022500466A
(ja)
|
2018-09-21 |
2022-01-04 |
エナンタ ファーマシューティカルズ インコーポレイテッド |
抗ウイルス剤としての官能化複素環
|
|
US20230056135A1
(en)
*
|
2018-10-05 |
2023-02-23 |
Emory University |
Monomer and multimeric anti-hbv agents
|
|
CA3117449A1
(en)
|
2018-10-22 |
2020-04-30 |
Assembly Biosciences, Inc. |
5-membered heteroaryl carboxamide compounds for treatment of hbv
|
|
US20210395751A1
(en)
|
2018-10-31 |
2021-12-23 |
The University Of Sydney |
Compositions and methods for treating viral infections
|
|
WO2020106707A1
(en)
|
2018-11-19 |
2020-05-28 |
Enanta Pharmaceuticals, Inc. |
Apoptosis signal-regulating kinase 1 inhibitors and methods of use thereof
|
|
IL283190B2
(en)
|
2018-11-21 |
2025-08-01 |
Enanta Pharm Inc |
Functionalized heterocycles as antiviral agents
|
|
TW202415643A
(zh)
|
2018-12-12 |
2024-04-16 |
加拿大商愛彼特生物製藥公司 |
經取代之芳基甲基脲類及雜芳基甲基脲類、其類似物及其使用方法
|
|
US11952330B2
(en)
|
2019-02-05 |
2024-04-09 |
Board Of Regents, The University Of Texas System |
Antibiotic ammonium compounds and methods for the treatment of bacterial infections
|
|
WO2020169784A1
(en)
|
2019-02-22 |
2020-08-27 |
Janssen Sciences Ireland Unlimited Company |
Amide derivatives useful in the treatment of hbv infection or hbv-induced diseases
|
|
US11466033B2
(en)
|
2019-03-25 |
2022-10-11 |
Enanta Pharmaceuticals, Inc. |
Substituted pyridines as apoptosis signal-regulating kinase 1 inhibitors
|
|
AR119732A1
(es)
|
2019-05-06 |
2022-01-05 |
Janssen Sciences Ireland Unlimited Co |
Derivados de amida útiles en el tratamiento de la infección por vhb o de enfermedades inducidas por vhb
|
|
UY38705A
(es)
|
2019-05-23 |
2020-12-31 |
Irbm S P A |
Inhibidores tricíclicos sustituidos con oxalamido del virus de hepatitis b
|
|
EP3741762A1
(en)
|
2019-05-23 |
2020-11-25 |
Irbm S.P.A. |
Oxalamido-substituted tricyclic inhibitors of hepatitis b virus
|
|
EP3825318A1
(en)
|
2019-11-25 |
2021-05-26 |
Promidis S.r.l. |
Oxalamido-substituted tricyclic inhibitors of hepatitis b virus
|
|
BR112021023622A2
(pt)
|
2019-05-24 |
2022-04-19 |
Assembly Biosciences Inc |
Composições farmaceuticas para o tratamento de hbv
|
|
WO2020247444A1
(en)
|
2019-06-03 |
2020-12-10 |
Enanta Pharmaceuticals, Inc, |
Hepatitis b antiviral agents
|
|
WO2020247575A1
(en)
|
2019-06-04 |
2020-12-10 |
Enanta Pharmaceuticals, Inc. |
Hepatitis b antiviral agents
|
|
WO2020247561A1
(en)
|
2019-06-04 |
2020-12-10 |
Enanta Pharmaceuticals, Inc, |
Hepatitis b antiviral agents
|
|
WO2020255013A1
(en)
|
2019-06-18 |
2020-12-24 |
Janssen Sciences Ireland Unlimited Company |
Combination of hepatitis b virus (hbv) vaccines and capsid assembly modulators being amide derivatives
|
|
US11738019B2
(en)
|
2019-07-11 |
2023-08-29 |
Enanta Pharmaceuticals, Inc. |
Substituted heterocycles as antiviral agents
|
|
US11236108B2
(en)
|
2019-09-17 |
2022-02-01 |
Enanta Pharmaceuticals, Inc. |
Functionalized heterocycles as antiviral agents
|
|
CN114729376A
(zh)
|
2019-09-23 |
2022-07-08 |
欧米茄治疗公司 |
用于调节肝细胞核因子4α(HNF4α)基因表达的组合物和方法
|
|
EP4048807A1
(en)
|
2019-09-23 |
2022-08-31 |
Omega Therapeutics, Inc. |
Compositions and methods for modulating apolipoprotein b (apob) gene expression
|
|
CN114846051A
(zh)
|
2019-12-20 |
2022-08-02 |
阿布特斯生物制药公司 |
合成方法和中间体
|
|
CA3173528A1
(en)
|
2020-03-11 |
2021-09-16 |
Omega Therapeutics, Inc. |
Compositions and methods for modulating forkhead box p3 (foxp3) gene expression
|
|
WO2021188414A1
(en)
|
2020-03-16 |
2021-09-23 |
Enanta Pharmaceuticals, Inc. |
Functionalized heterocyclic compounds as antiviral agents
|
|
KR20210126507A
(ko)
|
2020-04-10 |
2021-10-20 |
주식회사 스탠다임 |
벤즈아미드 화합물을 포함하는 암 예방 또는 치료용 조성물
|
|
CN111349056B
(zh)
*
|
2020-04-16 |
2022-08-02 |
南京安纳康生物科技有限公司 |
用于乙型肝炎病毒感染的抗病毒剂
|
|
CN111393391B
(zh)
*
|
2020-04-16 |
2022-07-26 |
南京安纳康生物科技有限公司 |
用于乙型肝炎病毒感染的抗病毒剂
|
|
CN121248511A
(zh)
|
2020-04-22 |
2026-01-02 |
组装生物科学股份有限公司 |
用于治疗hbv的5元杂芳基甲酰胺化合物
|
|
WO2021216661A1
(en)
|
2020-04-22 |
2021-10-28 |
Assembly Biosciences, Inc. |
Pyrazole carboxamide compounds for treatment of hbv
|
|
WO2021216642A1
(en)
|
2020-04-22 |
2021-10-28 |
Assembly Biosciences, Inc. |
Pyrazole carboxamide compounds for treatment of hbv
|
|
WO2021216660A1
(en)
|
2020-04-22 |
2021-10-28 |
Assembly Biosciences, Inc. |
5-membered heteroaryl carboxamide compounds for treatment of hbv
|
|
WO2021222150A2
(en)
|
2020-04-28 |
2021-11-04 |
Anwita Biosciences, Inc. |
Interleukin-2 polypeptides and fusion proteins thereof, and their pharmaceutical compositions and therapeutic applications
|
|
CA3198317A1
(en)
*
|
2020-11-10 |
2022-05-19 |
Kevin J. Wilson |
Compounds and uses thereof
|
|
EP4367242A2
(en)
|
2021-07-07 |
2024-05-15 |
Omega Therapeutics, Inc. |
Compositions and methods for modulating secreted frizzled receptor protein 1 (sfrp1) gene expression
|
|
WO2023069544A1
(en)
|
2021-10-20 |
2023-04-27 |
Assembly Biosciences, Inc. |
5-membered heteroaryl carboxamide compounds for treatment of hbv
|
|
WO2023069545A1
(en)
|
2021-10-20 |
2023-04-27 |
Assembly Biosciences, Inc. |
5-membered heteroaryl carboxamide compounds for treatment of hbv
|
|
WO2023069547A1
(en)
|
2021-10-20 |
2023-04-27 |
Assembly Biosciences, Inc. |
5-membered heteroaryl carboxamide compounds for treatment of hbv
|
|
KR102617049B1
(ko)
|
2021-12-30 |
2023-12-21 |
장고옥 |
헤어고데기
|
|
WO2023164181A1
(en)
|
2022-02-25 |
2023-08-31 |
Assembly Biosciences, Inc. |
Benzothia(dia)zepine compounds for treatment of hbv and hdv
|
|
WO2023164179A1
(en)
|
2022-02-25 |
2023-08-31 |
Assembly Biosciences, Inc. |
Benzothia(dia)zepine compounds for treatment of hbv and hdv
|
|
US20250163009A1
(en)
|
2022-02-25 |
2025-05-22 |
Assembly Biosciences, Inc. |
Benzothia(dia)zepine compounds for treatment of hbv and hdv
|
|
WO2023164186A1
(en)
|
2022-02-25 |
2023-08-31 |
Assembly Biosciences, Inc. |
Benzothia(dia)zepine compounds for treatment of hbv and hdv
|
|
MX2024011545A
(es)
|
2022-03-23 |
2024-09-26 |
Ideaya Biosciences Inc |
Compuestos de indazol sustituidos con piperazina como inhibidores de parg.
|
|
JPWO2024029481A1
(https=)
*
|
2022-08-01 |
2024-02-08 |
|
|
|
JP2025529185A
(ja)
*
|
2022-08-30 |
2025-09-04 |
パンネックス セラピューティクス インコーポレイテッド |
パネキシン-1調節剤及びパネキシン-1が関与する疾患の治療方法
|
|
CN115677545B
(zh)
*
|
2022-10-28 |
2024-03-15 |
潍坊医学院 |
一种抗hbv磺胺苯甲酰胺类衍生物及其制备方法和应用
|
|
CN116410106B
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