JP2017523225A5 - - Google Patents

Download PDF

Info

Publication number
JP2017523225A5
JP2017523225A5 JP2017506964A JP2017506964A JP2017523225A5 JP 2017523225 A5 JP2017523225 A5 JP 2017523225A5 JP 2017506964 A JP2017506964 A JP 2017506964A JP 2017506964 A JP2017506964 A JP 2017506964A JP 2017523225 A5 JP2017523225 A5 JP 2017523225A5
Authority
JP
Japan
Prior art keywords
alkyl
substituted
carboxylic acid
formula
heterocycle
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
JP2017506964A
Other languages
English (en)
Japanese (ja)
Other versions
JP2017523225A (ja
JP6577570B2 (ja
Filing date
Publication date
Application filed filed Critical
Priority claimed from PCT/EP2015/068257 external-priority patent/WO2016020526A1/en
Publication of JP2017523225A publication Critical patent/JP2017523225A/ja
Publication of JP2017523225A5 publication Critical patent/JP2017523225A5/ja
Application granted granted Critical
Publication of JP6577570B2 publication Critical patent/JP6577570B2/ja
Expired - Fee Related legal-status Critical Current
Anticipated expiration legal-status Critical

Links

JP2017506964A 2014-08-08 2015-08-07 インフルエンザウイルス感染に使用するためのインドール類 Expired - Fee Related JP6577570B2 (ja)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
EP14180331 2014-08-08
EP14180331.2 2014-08-08
PCT/EP2015/068257 WO2016020526A1 (en) 2014-08-08 2015-08-07 Indoles for use in influenza virus infection

Publications (3)

Publication Number Publication Date
JP2017523225A JP2017523225A (ja) 2017-08-17
JP2017523225A5 true JP2017523225A5 (https=) 2019-08-22
JP6577570B2 JP6577570B2 (ja) 2019-09-18

Family

ID=51298610

Family Applications (1)

Application Number Title Priority Date Filing Date
JP2017506964A Expired - Fee Related JP6577570B2 (ja) 2014-08-08 2015-08-07 インフルエンザウイルス感染に使用するためのインドール類

Country Status (18)

Country Link
US (1) US10597390B2 (https=)
EP (1) EP3177609A1 (https=)
JP (1) JP6577570B2 (https=)
KR (1) KR102488479B1 (https=)
CN (1) CN106573920B (https=)
AU (1) AU2015298876B2 (https=)
BR (1) BR112017002370B1 (https=)
CA (1) CA2954751C (https=)
CL (1) CL2017000309A1 (https=)
EA (1) EA201790266A1 (https=)
IL (1) IL250408B (https=)
MA (1) MA40547A (https=)
MX (1) MX381488B (https=)
PH (1) PH12017500207A1 (https=)
SG (1) SG11201700956VA (https=)
UA (1) UA124609C2 (https=)
WO (1) WO2016020526A1 (https=)
ZA (1) ZA201700952B (https=)

Families Citing this family (22)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
LT3141252T (lt) 2009-06-17 2018-11-12 Vertex Pharmaceuticals Inc. Gripo virusų replikacijos inhibitoriai
UA118010C2 (uk) 2011-08-01 2018-11-12 Вертекс Фармасьютікалз Інкорпорейтед Інгібітори реплікації вірусів грипу
CN106573920B (zh) 2014-08-08 2020-11-10 爱尔兰詹森科学公司 用于在流感病毒感染中使用的吲哚
EP3294717B1 (en) 2015-05-13 2020-07-29 Vertex Pharmaceuticals Inc. Methods of preparing inhibitors of influenza viruses replication
EP3294735B8 (en) 2015-05-13 2022-01-05 Vertex Pharmaceuticals Incorporated Inhibitors of influenza viruses replication
SG11201804225PA (en) 2015-12-09 2018-06-28 Sunshine Lake Pharma Co Ltd Inhibitors of influenza virus replication, application methods and uses thereof
DK3400225T3 (da) * 2016-01-07 2022-01-03 Janssen Sciences Ireland Unlimited Co Pentansyrederivater substitueret med pyrrolo-[2,3-b]pyrimidinpyridiner til behandling af influenzavirusinfektioner
WO2017133670A1 (en) * 2016-02-05 2017-08-10 Savira Pharmaceuticals Gmbh Pyridine and pyrimidine derivatives and their use in treatment, amelioration or prevention of influenza
WO2018033082A1 (en) * 2016-08-16 2018-02-22 Sunshine Lake Pharma Co., Ltd. Inhibitors of influenza virus replication, application methods and uses thereof
WO2018041091A1 (en) * 2016-08-30 2018-03-08 Sunshine Lake Pharma Co., Ltd. Inhibitors of influenza virus replication, application methods and uses thereof
RU2727772C1 (ru) 2016-09-05 2020-07-23 Гуандун Рэйновент Байотек Ко., Лтд. Производные пиримидина против вируса гриппа
JP7034162B2 (ja) 2016-12-15 2022-03-11 サンシャイン・レイク・ファーマ・カンパニー・リミテッド インフルエンザウイルス複製の阻害剤及びその使用
CA3047404A1 (en) * 2016-12-23 2018-06-28 Aquinnah Pharmaceuticals, Inc. Compounds, compositions and methods of use
CN108276401B (zh) 2017-01-05 2020-12-22 广东东阳光药业有限公司 流感病毒复制抑制剂及其用途
WO2018157830A1 (en) 2017-03-02 2018-09-07 Sunshine Lake Pharma Co., Ltd. Inhibitors of influenza virus replication and uses thereof
CN108727369B (zh) * 2017-04-25 2023-06-09 广东东阳光药业有限公司 流感病毒复制抑制剂及其用途
JP7031002B2 (ja) 2018-03-05 2022-03-07 広東衆生睿創生物科技有限公司 ピリジノイミダゾール系化合物の結晶型、塩型及びその製造方法
WO2021012864A1 (zh) * 2019-07-22 2021-01-28 广东众生睿创生物科技有限公司 嘧啶衍生物的优势盐型及其晶型
CN113045475A (zh) * 2019-12-27 2021-06-29 上海泓博智源医药股份有限公司 一种5-溴-7-甲基吲哚的制备方法
AU2021313150A1 (en) * 2020-07-20 2023-03-16 Nido Biosciences, Inc. Indole compounds as androgen receptor modulators
EP4214201A4 (en) * 2020-09-18 2024-10-09 Sunshine Lake Pharma Co., Ltd. PROCESS FOR THE PREPARATION OF SUBSTITUTED PYRIMIDINE PIPERAZINE COMPOUNDS
CR20250176A (es) * 2022-10-12 2025-06-25 Maze Therapeutics Inc Inhibidores del miembro 19 de la familia de portadores de solutos 6a (slc6a19) y métodos de uso de los mismos

Family Cites Families (14)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ES2364340T3 (es) 2004-03-30 2011-08-31 Vertex Pharmaceuticals Incorporated Azaindoles útiles como inhibidores de jak y otras proteína quinasas.
UA95940C2 (uk) 2006-01-17 2011-09-26 Вертекс Фармасьютикалс Інкорпорейтед Азаіндоли як інгібітори кіназ януса
LT3141252T (lt) * 2009-06-17 2018-11-12 Vertex Pharmaceuticals Inc. Gripo virusų replikacijos inhibitoriai
US9326987B2 (en) * 2010-09-08 2016-05-03 Glaxo Group Limited Indazole derivatives for use in the treatment of influenza virus infection
RU2013132681A (ru) * 2010-12-16 2015-01-27 Вертекс Фармасьютикалз Инкорпорейтед Ингибиторы репликации вирусов гриппа
CN103562205A (zh) * 2010-12-16 2014-02-05 沃泰克斯药物股份有限公司 流感病毒复制的抑制剂
UA118010C2 (uk) * 2011-08-01 2018-11-12 Вертекс Фармасьютікалз Інкорпорейтед Інгібітори реплікації вірусів грипу
JP6096778B2 (ja) 2011-09-01 2017-03-15 エフ・ホフマン−ラ・ロシュ・アクチェンゲゼルシャフト ピロロピラジンキナーゼ阻害剤
EP2858984A1 (en) 2012-06-08 2015-04-15 Vertex Pharmaceuticals Inc. Inhibitors of influenza viruses replication
LT3068776T (lt) 2013-11-13 2019-08-12 Vertex Pharmaceuticals Incorporated Gripo virusų replikacijos inhibitoriai
AR101448A1 (es) 2014-08-08 2016-12-21 Bayer Cropscience Ag Compuestos sustituidos por halógeno
CN106573920B (zh) 2014-08-08 2020-11-10 爱尔兰詹森科学公司 用于在流感病毒感染中使用的吲哚
AR101401A1 (es) 2014-08-08 2016-12-14 Bayer Cropscience Ag Derivados de bipirazol, sustituidos con halógeno
CN104592038A (zh) 2015-01-12 2015-05-06 烟台万润精细化工股份有限公司 一种5,5-二甲基-1,3-环己二胺的制备方法

Similar Documents

Publication Publication Date Title
JP2017523225A5 (https=)
JP2015024998A5 (https=)
JP2020507589A5 (https=)
JP2017531619A5 (https=)
ZA202006378B (en) N-heterocyclic five-membered ring-containing capsid protein assembly inhibitor, pharmaceutical composition thereof, and use thereof
JP2019501879A5 (https=)
JP2016518434A5 (https=)
JP2020531422A5 (https=)
HRP20211278T1 (hr) Supstituirani derivati indolina kao inhibitori replikacije denga virusa
JP2017531038A5 (https=)
EA201992082A1 (ru) Ингибитор поверхностного антигена вируса гепатита b
JP2020532547A5 (https=)
JP2019510034A5 (https=)
JP2017517565A5 (https=)
JP2017528503A5 (https=)
JP2015537020A5 (https=)
RU2013121788A (ru) Ингибиторы репликации вич
JP2019500387A5 (https=)
JP2014511891A5 (https=)
JP2013542247A5 (https=)
JP2013543896A5 (https=)
HRP20210038T1 (hr) Pirolopirimidini za uporabu u infekciji virusom gripe
JP2016540742A5 (https=)
JP2016534063A5 (https=)
JP2015051983A5 (https=)