DK3400225T3 - Pentansyrederivater substitueret med pyrrolo-[2,3-b]pyrimidinpyridiner til behandling af influenzavirusinfektioner - Google Patents
Pentansyrederivater substitueret med pyrrolo-[2,3-b]pyrimidinpyridiner til behandling af influenzavirusinfektioner Download PDFInfo
- Publication number
- DK3400225T3 DK3400225T3 DK17700614.5T DK17700614T DK3400225T3 DK 3400225 T3 DK3400225 T3 DK 3400225T3 DK 17700614 T DK17700614 T DK 17700614T DK 3400225 T3 DK3400225 T3 DK 3400225T3
- Authority
- DK
- Denmark
- Prior art keywords
- influenzavirus
- pyridines
- pyrrolo
- pyrimidine
- infections
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
- C07D487/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
- C07D487/04—Ortho-condensed systems
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/4353—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom ortho- or peri-condensed with heterocyclic ring systems
- A61K31/437—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom ortho- or peri-condensed with heterocyclic ring systems the heterocyclic ring system containing a five-membered ring having nitrogen as a ring hetero atom, e.g. indolizine, beta-carboline
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
- A61K31/4427—Non condensed pyridines; Hydrogenated derivatives thereof containing further heterocyclic ring systems
- A61K31/444—Non condensed pyridines; Hydrogenated derivatives thereof containing further heterocyclic ring systems containing a six-membered ring with nitrogen as a ring heteroatom, e.g. amrinone
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
- A61K31/505—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
- A61K31/506—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim not condensed and containing further heterocyclic rings
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
- A61K31/505—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
- A61K31/519—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim ortho- or peri-condensed with heterocyclic rings
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
- A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
- A61P31/14—Antivirals for RNA viruses
- A61P31/16—Antivirals for RNA viruses for influenza or rhinoviruses
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
- C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
- C07D471/04—Ortho-condensed systems
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
EP16150457 | 2016-01-07 | ||
PCT/EP2017/050175 WO2017118680A1 (en) | 2016-01-07 | 2017-01-05 | Functionalized pentanoic acids for use in influenza viral infections |
Publications (1)
Publication Number | Publication Date |
---|---|
DK3400225T3 true DK3400225T3 (da) | 2022-01-03 |
Family
ID=55070906
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
DK17700614.5T DK3400225T3 (da) | 2016-01-07 | 2017-01-05 | Pentansyrederivater substitueret med pyrrolo-[2,3-b]pyrimidinpyridiner til behandling af influenzavirusinfektioner |
Country Status (16)
Country | Link |
---|---|
US (1) | US10526338B2 (da) |
EP (1) | EP3400225B1 (da) |
JP (1) | JP7001601B2 (da) |
KR (1) | KR20180099839A (da) |
CN (1) | CN108473493B (da) |
AU (1) | AU2017205261B2 (da) |
CA (1) | CA3007758A1 (da) |
DK (1) | DK3400225T3 (da) |
EA (1) | EA201891576A1 (da) |
ES (1) | ES2902403T3 (da) |
HR (1) | HRP20211749T1 (da) |
HU (1) | HUE056457T2 (da) |
LT (1) | LT3400225T (da) |
MA (1) | MA43583A (da) |
SI (1) | SI3400225T1 (da) |
WO (1) | WO2017118680A1 (da) |
Families Citing this family (8)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
RS55341B1 (sr) | 2009-06-17 | 2017-03-31 | Vertex Pharma | Inhibitori replikacije virusa gripa |
UA118010C2 (uk) | 2011-08-01 | 2018-11-12 | Вертекс Фармасьютікалз Інкорпорейтед | Інгібітори реплікації вірусів грипу |
EP3294735B8 (en) | 2015-05-13 | 2022-01-05 | Vertex Pharmaceuticals Incorporated | Inhibitors of influenza viruses replication |
CN107759571B (zh) | 2016-08-16 | 2021-03-02 | 广东东阳光药业有限公司 | 流感病毒复制抑制剂及其使用方法和用途 |
WO2018041091A1 (en) | 2016-08-30 | 2018-03-08 | Sunshine Lake Pharma Co., Ltd. | Inhibitors of influenza virus replication, application methods and uses thereof |
CN108218873B (zh) | 2016-12-15 | 2020-07-07 | 广东东阳光药业有限公司 | 流感病毒复制抑制剂及其用途 |
US11098042B2 (en) | 2017-01-05 | 2021-08-24 | Sunshine Lake Pharma Co., Ltd. | Inhibitors of influenza virus replication and uses thereof |
WO2018157830A1 (en) | 2017-03-02 | 2018-09-07 | Sunshine Lake Pharma Co., Ltd. | Inhibitors of influenza virus replication and uses thereof |
Family Cites Families (7)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
RS55341B1 (sr) * | 2009-06-17 | 2017-03-31 | Vertex Pharma | Inhibitori replikacije virusa gripa |
UA118010C2 (uk) * | 2011-08-01 | 2018-11-12 | Вертекс Фармасьютікалз Інкорпорейтед | Інгібітори реплікації вірусів грипу |
WO2013184985A1 (en) * | 2012-06-08 | 2013-12-12 | Vertex Pharmaceuticals Incorporated | Inhibitors of influenza viruses replication |
MX361585B (es) * | 2012-11-16 | 2018-12-11 | Janssen Sciences Ireland Uc | Derivados 2-aminoquinazolínicos sustituidos heterocíclicos para el tratamiento de infecciones víricas. |
AU2015298876B2 (en) | 2014-08-08 | 2020-02-13 | Janssen Sciences Ireland Uc | Indoles for use in influenza virus infection |
MX2017002972A (es) * | 2014-09-08 | 2017-05-30 | Janssen Sciences Ireland Uc | Pirrolopirimidinas para usarse en la infeccion por el virus de la gripe. |
EP3294735B8 (en) * | 2015-05-13 | 2022-01-05 | Vertex Pharmaceuticals Incorporated | Inhibitors of influenza viruses replication |
-
2017
- 2017-01-05 LT LTEPPCT/EP2017/050175T patent/LT3400225T/lt unknown
- 2017-01-05 ES ES17700614T patent/ES2902403T3/es active Active
- 2017-01-05 WO PCT/EP2017/050175 patent/WO2017118680A1/en active Application Filing
- 2017-01-05 HU HUE17700614A patent/HUE056457T2/hu unknown
- 2017-01-05 EA EA201891576A patent/EA201891576A1/ru unknown
- 2017-01-05 HR HRP20211749TT patent/HRP20211749T1/hr unknown
- 2017-01-05 MA MA043583A patent/MA43583A/fr unknown
- 2017-01-05 KR KR1020187022012A patent/KR20180099839A/ko not_active Application Discontinuation
- 2017-01-05 SI SI201730989T patent/SI3400225T1/sl unknown
- 2017-01-05 CN CN201780006031.XA patent/CN108473493B/zh not_active Expired - Fee Related
- 2017-01-05 DK DK17700614.5T patent/DK3400225T3/da active
- 2017-01-05 JP JP2018535337A patent/JP7001601B2/ja active Active
- 2017-01-05 AU AU2017205261A patent/AU2017205261B2/en not_active Ceased
- 2017-01-05 US US16/068,315 patent/US10526338B2/en not_active Expired - Fee Related
- 2017-01-05 CA CA3007758A patent/CA3007758A1/en active Pending
- 2017-01-05 EP EP17700614.5A patent/EP3400225B1/en active Active
Also Published As
Publication number | Publication date |
---|---|
CA3007758A1 (en) | 2017-07-13 |
CN108473493A (zh) | 2018-08-31 |
LT3400225T (lt) | 2021-12-10 |
EA201891576A1 (ru) | 2018-11-30 |
WO2017118680A1 (en) | 2017-07-13 |
US20190023713A1 (en) | 2019-01-24 |
US10526338B2 (en) | 2020-01-07 |
JP2019505518A (ja) | 2019-02-28 |
CN108473493B (zh) | 2022-05-27 |
JP7001601B2 (ja) | 2022-01-19 |
SI3400225T1 (sl) | 2022-01-31 |
MA43583A (fr) | 2021-05-19 |
AU2017205261A1 (en) | 2018-06-28 |
KR20180099839A (ko) | 2018-09-05 |
EP3400225B1 (en) | 2021-11-10 |
EP3400225A1 (en) | 2018-11-14 |
HUE056457T2 (hu) | 2022-02-28 |
ES2902403T3 (es) | 2022-03-28 |
HRP20211749T1 (hr) | 2022-02-18 |
AU2017205261B2 (en) | 2021-03-25 |
Similar Documents
Publication | Publication Date | Title |
---|---|---|
DK3400225T3 (da) | Pentansyrederivater substitueret med pyrrolo-[2,3-b]pyrimidinpyridiner til behandling af influenzavirusinfektioner | |
HK1257146A1 (zh) | 新型的吡唑並[3,4-d]嘧啶化合物或其鹽 | |
DK3404031T3 (da) | Thieno[3,2-d]pyrimidinderivater til behandling af virusinfektioner | |
DK3429591T3 (da) | Substituerede thieno[2,3-D]pyrimidin-derivater som inhibitorer af Menin-MLL og fremgangsmåder til anvendelse | |
DK3230298T3 (da) | 3-substituerede 5-amino-6H-thiazolo[4,5-d]pyrimidin-2,7-dion forbindelser til behandling og forebyggelse af virusinfektion | |
MA46054A (fr) | Procédé de préparation de pyrazolo[1,5-a]pyrimidines et de sels de celles-ci | |
IL259169A (en) | Novel pyrazolo pyrimidine derivatives | |
DK3030563T3 (da) | Pyrrolo-[3,2-d]-pyrimidin-derivater til behandling af virale infektioner og andre sygdomme | |
DK3359542T3 (da) | Spiro[3h-indol-3,2'-pyrrolidin]-2(1h)-on-forbindelser og derivater som mdm2-p53-inhibitorer | |
DK3712152T3 (da) | 4,5,6,7-tetrahydro-1h-imidazo[4,5-c]pyridin og 1,4,5,6,7,8-hexahydroimidazo[4,5-d]azepinderivater som janus kinase-inhibitorer | |
DK3371185T3 (da) | 4,5,6,7-tetrahydro-1h-imidazo[4,5-c]pyridin og 1,4,5,6,7,8-hexahydroimidazo[4,5-d]azepinderivater som janus-kinase-inhibitorer | |
DK3348557T3 (da) | Imidazo[1,2-a]pyridiner til behandling eller forebyggelse af hyperurekæmi eller gigt | |
MA52593A (fr) | 1h-pyrazolo[4,3-b]pyridines en tant qu'inhibiteurs pde1 | |
DK3412673T3 (da) | Fremgangsmåde til fremstilling af pyrrolo[3,2-D]pyrimidin-forbindelse og mellemprodukter deraf | |
DK3177627T3 (da) | Imidazo[1,2-a]-pyrazolo[4,3-e]-pyrimidin-4-on-derivater med pde1-hæmmende aktivitet | |
DK3535263T3 (da) | Substituerede pyrido[3,4-b]indoler til behandling af bruskforstyrrelser | |
DK3697784T3 (da) | Imidazo[4,5-b]pyridinforbindelser og farmaceutiske sammensætninger deraf til behandling af inflammatoriske forstyrrelser | |
DK3194389T3 (da) | Ssao inhibitorer afledt af imidazo[4,5-c]pyridin | |
DK3459953T3 (da) | Hidtil ukendt 5h-pyrrolo[2,3-d]pyrimidin-6(7h)-on-derivat | |
DK3452465T3 (da) | Substituerede 2,4-diaminoquinolinderivater til anvendelse til behandling af proliferative sygdomme | |
DK3362453T3 (da) | Cykliske etherderivater af pyrazolo[1,5-a]pyrimidin-3-carboxyamid | |
GB201802644D0 (en) | Monocyclic,thieno, pyrido and pyrrolo pyrimidine compounds and methods of use and manufacture of the same | |
DK3218382T3 (da) | 2,3-dihydro-thiazolo[3,2-a]pyridin-5-on derivativer som antibiotika til behandling af klamydiainfektioner | |
DK3356329T3 (da) | Fremgangsmåde til fremstilling af 1-(4-methansulfonyl-2-trifluormethylbenzyl)-2-methyl-1H-pyrrolo[2,3-B]pyridin-3-yleddikesyre | |
DK3481805T3 (da) | Fremgangsmåde til fremstilling af halogenerede pyridinderivater |