DK3481805T3 - Fremgangsmåde til fremstilling af halogenerede pyridinderivater - Google Patents

Fremgangsmåde til fremstilling af halogenerede pyridinderivater Download PDF

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Publication number
DK3481805T3
DK3481805T3 DK17736603.6T DK17736603T DK3481805T3 DK 3481805 T3 DK3481805 T3 DK 3481805T3 DK 17736603 T DK17736603 T DK 17736603T DK 3481805 T3 DK3481805 T3 DK 3481805T3
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DK
Denmark
Prior art keywords
production
pyridine derivatives
halogenated pyridine
halogenated
derivatives
Prior art date
Application number
DK17736603.6T
Other languages
English (en)
Inventor
Marc Mosrin
Laura Hoffmeister
Nina Kausch-Busies
Rüdiger Fischer
Dominik Hager
David Wilcke
Matthieu Willot
Original Assignee
Bayer Cropscience Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
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Application filed by Bayer Cropscience Ag filed Critical Bayer Cropscience Ag
Application granted granted Critical
Publication of DK3481805T3 publication Critical patent/DK3481805T3/da

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    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D213/00Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
    • C07D213/02Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
    • C07D213/04Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D213/60Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D213/61Halogen atoms or nitro radicals
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D213/00Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
    • C07D213/02Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
    • C07D213/04Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D213/60Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D213/78Carbon atoms having three bonds to hetero atoms, with at the most one bond to halogen, e.g. ester or nitrile radicals
    • C07D213/79Acids; Esters
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D213/00Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
    • C07D213/02Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
    • C07D213/04Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D213/60Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D213/78Carbon atoms having three bonds to hetero atoms, with at the most one bond to halogen, e.g. ester or nitrile radicals
    • C07D213/79Acids; Esters
    • C07D213/803Processes of preparation
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07FACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
    • C07F3/00Compounds containing elements of Groups 2 or 12 of the Periodic Table
    • C07F3/06Zinc compounds

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  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Pyridine Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
DK17736603.6T 2016-07-05 2017-06-28 Fremgangsmåde til fremstilling af halogenerede pyridinderivater DK3481805T3 (da)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
EP16178022 2016-07-05
PCT/EP2017/065989 WO2018007224A1 (de) 2016-07-05 2017-06-28 Verfahren zur herstellung halogenierter pyridinderivate

Publications (1)

Publication Number Publication Date
DK3481805T3 true DK3481805T3 (da) 2023-04-11

Family

ID=56363777

Family Applications (1)

Application Number Title Priority Date Filing Date
DK17736603.6T DK3481805T3 (da) 2016-07-05 2017-06-28 Fremgangsmåde til fremstilling af halogenerede pyridinderivater

Country Status (15)

Country Link
US (1) US10766909B2 (da)
EP (1) EP3481805B1 (da)
JP (1) JP7034953B2 (da)
KR (1) KR102408111B1 (da)
CN (1) CN109476601B (da)
AR (1) AR108943A1 (da)
BR (1) BR112019000213B1 (da)
DK (1) DK3481805T3 (da)
ES (1) ES2941903T3 (da)
FI (1) FI3481805T3 (da)
IL (1) IL263970B (da)
MX (1) MX2019000254A (da)
TW (1) TWI766872B (da)
UY (1) UY37315A (da)
WO (1) WO2018007224A1 (da)

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
TWI820231B (zh) 2018-10-11 2023-11-01 德商拜耳廠股份有限公司 用於製備經取代咪唑衍生物之方法

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3947457A (en) 1974-12-27 1976-03-30 The Dow Chemical Company Method for preparing 2,5-dihalo- and 2,5,6-trihalopyridines
US8569337B2 (en) * 2008-07-23 2013-10-29 Vertex Pharmaceuticals Incorporated Tri-cyclic pyrazolopyridine kinase inhibitors
JP5802756B2 (ja) 2010-10-20 2015-11-04 ファイザー・インク スムーズンド受容体モジュレーターとしてのピリジン−2−誘導体
WO2016010897A1 (en) 2014-07-14 2016-01-21 Incyte Corporation Bicyclic heteroaromatic carboxamide compounds useful as pim kinase inhibitors

Also Published As

Publication number Publication date
CN109476601A (zh) 2019-03-15
JP7034953B2 (ja) 2022-03-14
IL263970A (en) 2019-01-31
BR112019000213B1 (pt) 2022-10-25
MX2019000254A (es) 2019-05-27
JP2019521123A (ja) 2019-07-25
TWI766872B (zh) 2022-06-11
BR112019000213A2 (pt) 2019-04-16
CN109476601B (zh) 2022-10-28
AR108943A1 (es) 2018-10-10
US20190330241A1 (en) 2019-10-31
IL263970B (en) 2021-06-30
US10766909B2 (en) 2020-09-08
FI3481805T3 (fi) 2023-04-25
ES2941903T3 (es) 2023-05-26
EP3481805A1 (de) 2019-05-15
KR102408111B1 (ko) 2022-06-10
UY37315A (es) 2018-01-31
TW201811747A (zh) 2018-04-01
KR20190025626A (ko) 2019-03-11
EP3481805B1 (de) 2023-01-18
WO2018007224A1 (de) 2018-01-11

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