JP2024542969A5 - - Google Patents
Info
- Publication number
- JP2024542969A5 JP2024542969A5 JP2024524569A JP2024524569A JP2024542969A5 JP 2024542969 A5 JP2024542969 A5 JP 2024542969A5 JP 2024524569 A JP2024524569 A JP 2024524569A JP 2024524569 A JP2024524569 A JP 2024524569A JP 2024542969 A5 JP2024542969 A5 JP 2024542969A5
- Authority
- JP
- Japan
- Prior art keywords
- alkyl
- cycloalkyl
- heterocycloalkyl
- heteroaryl
- aryl
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
Applications Claiming Priority (5)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CNPCT/CN2021/128243 | 2021-11-02 | ||
| CN2021128243 | 2021-11-02 | ||
| CNPCT/CN2022/117034 | 2022-09-05 | ||
| CN2022117034 | 2022-09-05 | ||
| PCT/CN2022/128916 WO2023078231A1 (en) | 2021-11-02 | 2022-11-01 | Sars-cov-2 inhibitors for treating coronavirus infections |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JP2024542969A JP2024542969A (ja) | 2024-11-19 |
| JP2024542969A5 true JP2024542969A5 (https=) | 2025-10-22 |
Family
ID=86240657
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2024524569A Pending JP2024542969A (ja) | 2021-11-02 | 2022-11-01 | コロナウイルス感染を処置するためのｓａｒｓ－ｃｏｖ－２阻害剤 |
Country Status (9)
| Country | Link |
|---|---|
| US (3) | US20260049062A1 (https=) |
| EP (1) | EP4426682A4 (https=) |
| JP (1) | JP2024542969A (https=) |
| CN (1) | CN118510759A (https=) |
| AR (1) | AR127533A1 (https=) |
| PY (1) | PY2295067A (https=) |
| TW (1) | TW202322793A (https=) |
| UY (1) | UY40000A (https=) |
| WO (1) | WO2023078231A1 (https=) |
Families Citing this family (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| UY40000A (es) | 2021-11-02 | 2023-05-31 | Insilico Medicine Ip Ltd | Inhibidores del sars-cov-2 para tratar infecciones por coronavirus |
| WO2024174966A1 (en) * | 2023-02-20 | 2024-08-29 | Insilico Medicine Ip Limited | Mpro inhibitors for treating coronavirus infections |
| WO2024222796A1 (en) * | 2023-04-26 | 2024-10-31 | Insilico Medicine Ip Limited | Crystalline sars-cov-2 inhibitor and uses thereof |
| WO2025067202A1 (en) * | 2023-09-25 | 2025-04-03 | Insilico Medicine Ip Limited | 3cl-protease inhibitors for treating or preventing veterinary coronavirus infections |
Family Cites Families (22)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US7888376B2 (en) | 2005-11-23 | 2011-02-15 | Bristol-Myers Squibb Company | Heterocyclic CETP inhibitors |
| FR2932483A1 (fr) | 2008-06-13 | 2009-12-18 | Cytomics Systems | Composes utiles pour le traitement des cancers. |
| US20110269834A1 (en) | 2008-08-21 | 2011-11-03 | The Board Of Trustees Of The University Of Illinois | Compounds and methods for treating respiratory diseases |
| US20110077250A1 (en) * | 2009-06-26 | 2011-03-31 | Ryder Sean | Compounds for modulating rna binding proteins and uses therefor |
| CN103097340B (zh) | 2010-07-16 | 2018-03-16 | 安吉奥斯医药品有限公司 | 治疗活性组合物及其使用方法 |
| US9975885B2 (en) * | 2016-04-28 | 2018-05-22 | Purdue Research Foundation | Broad-spectrum non-covalent coronavirus protease inhibitors |
| US12516016B2 (en) | 2020-03-11 | 2026-01-06 | Sheldon Cao | GPX4 inhibitors, pharmaceutical compositions thereof, and their use for treating GPX4-mediated diseases |
| WO2021201201A1 (ja) | 2020-04-03 | 2021-10-07 | インタープロテイン株式会社 | 新型コロナウイルス感染症（ｃｏｖｉｄ－１９）の予防または治療剤および医薬組成物 |
| US20230340625A1 (en) | 2020-04-13 | 2023-10-26 | Sun Genomics, Inc. | Method and system for detecting and treating exposure to an infectious pathogen |
| US11124497B1 (en) | 2020-04-17 | 2021-09-21 | Pardes Biosciences, Inc. | Inhibitors of cysteine proteases and methods of use thereof |
| WO2021212039A1 (en) | 2020-04-17 | 2021-10-21 | Pardes Biosciences, Inc. | Inhibitors of cysteine proteases and methods of use thereof |
| JP2023524489A (ja) * | 2020-04-30 | 2023-06-12 | インシリコ メディシン アイピー リミテッド | コロナウイルス感染症を処置するための共有結合修飾を有するｓａｒｓ－ｃｏｖ－２阻害剤 |
| US11174231B1 (en) | 2020-06-09 | 2021-11-16 | Pardes Biosciences, Inc. | Inhibitors of cysteine proteases and methods of use thereof |
| BR112021023814A2 (pt) | 2020-06-09 | 2022-12-20 | Pardes Biosciences Inc | Inibidores de proteases de cisteína e métodos de uso das mesmas |
| WO2022023960A1 (en) | 2020-07-27 | 2022-02-03 | Fundación Universitaria San Antonio (Ucam) | Methods of treating and preventing coronavirus infection and disrupting coronavirus replication |
| WO2022119854A1 (en) | 2020-12-01 | 2022-06-09 | Purdue Research Foundation | Compounds for the treatment of sars |
| US20240083885A1 (en) * | 2020-12-04 | 2024-03-14 | Arizona Board Of Regents On Behalf Of The University Of Arizona | Compositions and methods for inhibiting m pro protease activity and for preventing and treating sars-cov-2 infection |
| WO2022221686A1 (en) | 2021-04-15 | 2022-10-20 | Pardes Biosciences, Inc. | Inhibitors of cysteine proteases and methods of use thereof |
| US11795159B2 (en) | 2021-05-26 | 2023-10-24 | Purdue Research Foundation | Compounds for the treatment of SARS |
| WO2023078238A1 (en) | 2021-11-02 | 2023-05-11 | Insilico Medicine Ip Limited | Sars-cov-2 inhibitors for treating coronavirus infections |
| UY40000A (es) * | 2021-11-02 | 2023-05-31 | Insilico Medicine Ip Ltd | Inhibidores del sars-cov-2 para tratar infecciones por coronavirus |
| CN113845440A (zh) | 2021-11-04 | 2021-12-28 | 沈阳药科大学 | 基于ugi反应合成的非天然肽类idh1抑制剂及其制法和应用 |
-
2022
- 2022-11-01 UY UY0001040000A patent/UY40000A/es unknown
- 2022-11-01 CN CN202280087395.6A patent/CN118510759A/zh active Pending
- 2022-11-01 AR ARP220102981A patent/AR127533A1/es unknown
- 2022-11-01 EP EP22889255.0A patent/EP4426682A4/en active Pending
- 2022-11-01 JP JP2024524569A patent/JP2024542969A/ja active Pending
- 2022-11-01 US US18/705,742 patent/US20260049062A1/en active Pending
- 2022-11-01 PY PY202202295067A patent/PY2295067A/es unknown
- 2022-11-01 WO PCT/CN2022/128916 patent/WO2023078231A1/en not_active Ceased
- 2022-11-01 TW TW111141596A patent/TW202322793A/zh unknown
-
2023
- 2023-02-08 US US18/107,127 patent/US11731944B2/en active Active
- 2023-06-22 US US18/339,366 patent/US20240025860A1/en not_active Abandoned