CN118510759A - 用于治疗冠状病毒感染的sars-cov-2抑制剂 - Google Patents

用于治疗冠状病毒感染的sars-cov-2抑制剂 Download PDF

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CN118510759A
CN118510759A CN202280087395.6A CN202280087395A CN118510759A CN 118510759 A CN118510759 A CN 118510759A CN 202280087395 A CN202280087395 A CN 202280087395A CN 118510759 A CN118510759 A CN 118510759A
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compound
alkyl
heterocycloalkyl
cycloalkyl
pharmaceutically acceptable
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丁晓
彭晶晶
任峰
丁小雨
波格丹·扎格里贝尔尼
严·A·伊万年科夫
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Yingsi Intelligent Technology Intellectual Property Co ltd
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    • C07D233/96—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having three double bonds between ring members or between ring members and non-ring members
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    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
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    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
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    • A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
    • A61K31/4427—Non condensed pyridines; Hydrogenated derivatives thereof containing further heterocyclic ring systems
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    • A61K31/505—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
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    • A61K31/505—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
    • A61K31/506—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim not condensed and containing further heterocyclic rings
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CN202280087395.6A 2021-11-02 2022-11-01 用于治疗冠状病毒感染的sars-cov-2抑制剂 Pending CN118510759A (zh)

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CN2021128243 2021-11-02
CNPCT/CN2021/128243 2021-11-02
CNPCT/CN2022/117034 2022-09-05
CN2022117034 2022-09-05
PCT/CN2022/128916 WO2023078231A1 (en) 2021-11-02 2022-11-01 Sars-cov-2 inhibitors for treating coronavirus infections

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US (3) US20260049062A1 (https=)
EP (1) EP4426682A4 (https=)
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AR (1) AR127533A1 (https=)
PY (1) PY2295067A (https=)
TW (1) TW202322793A (https=)
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TW202322793A (zh) * 2021-11-02 2023-06-16 香港商英科智能有限公司 用於治療冠狀病毒感染之sars-cov-2抑制劑
WO2024174966A1 (en) * 2023-02-20 2024-08-29 Insilico Medicine Ip Limited Mpro inhibitors for treating coronavirus infections
WO2024222796A1 (en) * 2023-04-26 2024-10-31 Insilico Medicine Ip Limited Crystalline sars-cov-2 inhibitor and uses thereof
WO2025067202A1 (en) * 2023-09-25 2025-04-03 Insilico Medicine Ip Limited 3cl-protease inhibitors for treating or preventing veterinary coronavirus infections

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