JP2024523459A5 - - Google Patents
Info
- Publication number
- JP2024523459A5 JP2024523459A5 JP2023578832A JP2023578832A JP2024523459A5 JP 2024523459 A5 JP2024523459 A5 JP 2024523459A5 JP 2023578832 A JP2023578832 A JP 2023578832A JP 2023578832 A JP2023578832 A JP 2023578832A JP 2024523459 A5 JP2024523459 A5 JP 2024523459A5
- Authority
- JP
- Japan
- Prior art keywords
- nitrophenyl
- pyrrole
- alilidene
- aminoguanidinium
- crystal morphology
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
Applications Claiming Priority (7)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| EP21180708 | 2021-06-21 | ||
| EP21180708.6 | 2021-06-21 | ||
| EP21180702.9 | 2021-06-21 | ||
| EP21180702 | 2021-06-21 | ||
| EP21209855 | 2021-11-23 | ||
| EP21209855.2 | 2021-11-23 | ||
| PCT/EP2022/066884 WO2022268814A1 (en) | 2021-06-21 | 2022-06-21 | Salts of phenyl pyrrole aminoguanidine and polymorphs of phenyl pyrrole aminoguanidinium salts |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JP2024523459A JP2024523459A (ja) | 2024-06-28 |
| JP2024523459A5 true JP2024523459A5 (https=) | 2025-06-27 |
Family
ID=84544160
Family Applications (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2023578832A Pending JP2024523459A (ja) | 2021-06-21 | 2022-06-21 | フェニルピロールアミノグアニジンの塩及びフェニルピロールアミノグアニジウム塩の多形体 |
| JP2023578136A Pending JP2024522817A (ja) | 2021-06-21 | 2022-06-21 | フェニルピロールアミノグアニジン塩及び製剤 |
Family Applications After (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2023578136A Pending JP2024522817A (ja) | 2021-06-21 | 2022-06-21 | フェニルピロールアミノグアニジン塩及び製剤 |
Country Status (11)
| Country | Link |
|---|---|
| US (3) | US20230271922A9 (https=) |
| EP (3) | EP4359076B1 (https=) |
| JP (2) | JP2024523459A (https=) |
| KR (2) | KR20240024818A (https=) |
| AU (2) | AU2022296767A1 (https=) |
| BR (1) | BR112023026909A2 (https=) |
| CA (2) | CA3220753A1 (https=) |
| ES (1) | ES3045575T3 (https=) |
| IL (2) | IL309102A (https=) |
| MX (2) | MX2023014174A (https=) |
| WO (2) | WO2022268814A1 (https=) |
Families Citing this family (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN120617247A (zh) * | 2020-03-31 | 2025-09-12 | 西奈克制药有限公司 | 症状性病毒性疾病的治疗 |
| EP4359076B1 (en) * | 2021-06-21 | 2025-08-06 | SynAct Pharma ApS | Phenyl pyrrole aminoguanidine salts and formulations |
| WO2023218048A1 (en) * | 2022-05-12 | 2023-11-16 | Synact Pharma Aps | Resomelagon and its derivatives for the treatment of cardiovascular disease, hypertension and atherosclerosis |
| CN120584099A (zh) * | 2022-12-21 | 2025-09-02 | 西奈克制药有限公司 | 苯基吡咯肼甲脒化合物的多晶型物 |
| WO2025124760A1 (en) | 2023-12-11 | 2025-06-19 | Synact Pharma Aps | Treatment of subpopulation of patients with rheumatoid arthritis |
Family Cites Families (40)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| SE9604348D0 (sv) | 1996-11-26 | 1996-11-26 | Wapharm Ab | Användning av hydroxyguanidiner |
| WO1999021571A1 (en) | 1997-10-27 | 1999-05-06 | Trega Biosciences, Inc. | Melanocortin receptor ligands and methods of using same |
| EP1076649A4 (en) | 1998-04-28 | 2010-06-02 | Trega Biosciences Inc | ISOQUINOLINE-BASED COMPOUNDS IN PLACE OF MELANOCORTIN RECEPTOR LIGANDS AND METHODS OF USE |
| WO1999064002A1 (en) | 1998-06-11 | 1999-12-16 | Merck & Co., Inc. | Spiropiperidine derivatives as melanocortin receptor agonists |
| CA2368431C (en) | 1999-03-29 | 2006-01-24 | The Procter & Gamble Company | Melanocortin receptor ligands |
| CA2377369A1 (en) | 1999-06-04 | 2000-12-14 | Merck & Co., Inc. | Substituted piperidines as melanocortin-4 receptor agonists |
| WO2001005401A1 (en) | 1999-07-16 | 2001-01-25 | Trega Biosciences, Inc. | Melanocortin receptor-3 ligands to treat sexual dysfunction |
| US6720317B1 (en) | 1999-09-17 | 2004-04-13 | Millennium Pharmaceuticals, Inc. | Inhibitors of factor Xa |
| CZ2002959A3 (cs) | 1999-09-17 | 2002-07-17 | Millennium Pharmaceuticals, Inc. | Inhibitory faktoru Xa |
| US6844367B1 (en) | 1999-09-17 | 2005-01-18 | Millennium Pharmaceuticals, Inc. | Benzamides and related inhibitors of factor Xa |
| US6632815B2 (en) | 1999-09-17 | 2003-10-14 | Millennium Pharmaceuticals, Inc. | Inhibitors of factor Xa |
| ES2316383T3 (es) | 1999-09-17 | 2009-04-16 | Millennium Pharmaceuticals, Inc. | Benzamidas e inhibidores relacionados del factor xa. |
| GB0002059D0 (en) | 2000-01-28 | 2000-03-22 | Melacure Therapeutics Ab | Novel aromatic amines |
| WO2001055106A2 (en) | 2000-01-28 | 2001-08-02 | Melacure Therapeutics Ab | Novel melanocortin receptor agonists and antagonists |
| WO2001055107A2 (en) | 2000-01-28 | 2001-08-02 | Melacure Therapeutics Ab | Aromatic amines and amides acting on the melanocortin receptors |
| KR100440370B1 (ko) | 2000-04-01 | 2004-07-19 | (주)명문엘씨 | 2중 사출에 의한 밀폐용기 뚜껑 |
| GB0019357D0 (en) | 2000-08-07 | 2000-09-27 | Melacure Therapeutics Ab | Novel phenyl guanidines |
| US6768024B1 (en) | 2000-08-04 | 2004-07-27 | Lion Bioscience Ag | Triamine derivative melanocortin receptor ligands and methods of using same |
| GB0019359D0 (en) | 2000-08-07 | 2000-09-27 | Melacure Therapeutics Ab | Novel guanidines |
| DZ3415A1 (fr) | 2000-08-31 | 2002-03-07 | Chiron Corp | Guanidinobenzamides comme mc4-r agonistes. |
| EP1370211A4 (en) | 2001-03-02 | 2005-02-09 | Bristol Myers Squibb Co | SIMULTANEOUS ADMINISTRATION OF MELANOCORTIN RECEPTOR AGONISTS AND A PHOSPHODIESTERASE HEMMER FOR THE TREATMENT OF DISEASES RELATED TO CYCLIC AMP |
| GB0119172D0 (en) | 2001-08-06 | 2001-09-26 | Melacure Therapeutics Ab | Phenyl pyrrole derivatives |
| CA2363528A1 (en) | 2001-11-19 | 2003-05-19 | Merck Patent Gesellschaft Mit Beschraenkter Haftung | Immediate release tablet containing naproxen sodium |
| GB2398299A (en) | 2003-02-13 | 2004-08-18 | Melacure Therapeutics Ab | Pharmaceutically active phenyl-pyrrole derivatives |
| MY149159A (en) | 2005-11-15 | 2013-07-31 | Hoffmann La Roche | Method for treating joint damage |
| NZ573457A (en) * | 2006-06-09 | 2011-06-30 | Action Pharma As | Phenyl pyrrole aminoguanidine derivatives |
| GB0624987D0 (en) | 2006-12-14 | 2007-01-24 | Acure Pharma Ab | Novel aminoguanidines as melanocortin receptor ligands |
| EP2045250A1 (en) | 2007-09-26 | 2009-04-08 | Action Pharma A/S | Ring-substituted phenyl pyrrole aminoguanidine derivatives |
| WO2009071101A1 (en) | 2007-12-07 | 2009-06-11 | Action Pharma A/S | N-modified aminoguanidine derivatives |
| WO2009074157A1 (en) | 2007-12-13 | 2009-06-18 | Action Pharma A/S | Fully-modified phenyl pyrrole aminoguanidines |
| JP2011190199A (ja) | 2010-03-12 | 2011-09-29 | Hideto Nakamura | 関節リウマチ薬 |
| RU2668791C2 (ru) | 2012-10-19 | 2018-10-02 | ТиЭксПи ФАРМА ГМБХ | АНАЛОГИ АЛЬФА- и ГАММА-MSH |
| WO2015162486A1 (en) | 2014-04-22 | 2015-10-29 | Txp Pharma Gmbh | Linear gamma msh with c- and / or n-terminal extensions of lysine and / or glutamic acid residues |
| WO2015162483A1 (en) | 2014-04-22 | 2015-10-29 | Txp Pharma Gmbh | Alpha- and gamma-msh analogues |
| WO2017141343A1 (ja) | 2016-02-16 | 2017-08-24 | 三菱電機株式会社 | 圧縮機 |
| CN112292125B (zh) * | 2018-06-22 | 2023-10-31 | 西奈克制药有限公司 | 蛋白尿的治疗 |
| WO2020107221A1 (en) | 2018-11-27 | 2020-06-04 | Tsinghua University | Chemical activators of nicotinamide mononucleotide adenlyly transferase 2 (nmnat2) and uses thereof |
| LT3773558T (lt) | 2019-05-10 | 2022-09-12 | Synact Pharma Aps | Kompleksinis artrito gydymas |
| CN120617247A (zh) * | 2020-03-31 | 2025-09-12 | 西奈克制药有限公司 | 症状性病毒性疾病的治疗 |
| EP4359076B1 (en) * | 2021-06-21 | 2025-08-06 | SynAct Pharma ApS | Phenyl pyrrole aminoguanidine salts and formulations |
-
2022
- 2022-06-21 EP EP22737436.0A patent/EP4359076B1/en active Active
- 2022-06-21 IL IL309102A patent/IL309102A/en unknown
- 2022-06-21 ES ES22737436T patent/ES3045575T3/es active Active
- 2022-06-21 KR KR1020237043107A patent/KR20240024818A/ko active Pending
- 2022-06-21 AU AU2022296767A patent/AU2022296767A1/en active Pending
- 2022-06-21 JP JP2023578832A patent/JP2024523459A/ja active Pending
- 2022-06-21 CA CA3220753A patent/CA3220753A1/en active Pending
- 2022-06-21 MX MX2023014174A patent/MX2023014174A/es unknown
- 2022-06-21 JP JP2023578136A patent/JP2024522817A/ja active Pending
- 2022-06-21 EP EP22735858.7A patent/EP4359383A1/en active Pending
- 2022-06-21 EP EP25194012.8A patent/EP4684835A3/en active Pending
- 2022-06-21 WO PCT/EP2022/066884 patent/WO2022268814A1/en not_active Ceased
- 2022-06-21 KR KR1020247000873A patent/KR20240024177A/ko active Pending
- 2022-06-21 IL IL309104A patent/IL309104A/en unknown
- 2022-06-21 MX MX2023014177A patent/MX2023014177A/es unknown
- 2022-06-21 WO PCT/EP2022/066906 patent/WO2022268825A1/en not_active Ceased
- 2022-06-21 AU AU2022300305A patent/AU2022300305A1/en active Pending
- 2022-06-21 BR BR112023026909A patent/BR112023026909A2/pt unknown
- 2022-06-21 CA CA3220756A patent/CA3220756A1/en active Pending
- 2022-08-23 US US17/821,500 patent/US20230271922A9/en active Pending
- 2022-12-14 US US18/065,702 patent/US20230114865A1/en active Pending
-
2024
- 2024-05-29 US US18/676,679 patent/US12239631B2/en active Active
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