AU2022296767A1 - Phenyl pyrrole aminoguanidine salts and formulations - Google Patents

Phenyl pyrrole aminoguanidine salts and formulations Download PDF

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Publication number
AU2022296767A1
AU2022296767A1 AU2022296767A AU2022296767A AU2022296767A1 AU 2022296767 A1 AU2022296767 A1 AU 2022296767A1 AU 2022296767 A AU2022296767 A AU 2022296767A AU 2022296767 A AU2022296767 A AU 2022296767A AU 2022296767 A1 AU2022296767 A1 AU 2022296767A1
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AU
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Prior art keywords
formulations
phenyl pyrrole
aminoguanidine salts
pyrrole aminoguanidine
salts
Prior art date
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Pending
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AU2022296767A
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English (en)
Inventor
Thomas Boesen
Bent HØJGAARD
Thomas Engelbrecht Nordkild Jonassen
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Synact Pharma ApS
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Synact Pharma ApS
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    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/40—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil
    • A61K31/402—1-aryl substituted, e.g. piretanide
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    • A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A61K31/505—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
    • A61K31/519—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim ortho- or peri-condensed with heterocyclic rings
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    • C07C233/83—Carboxylic acid amides having carbon atoms of carboxamide groups bound to carbon atoms of six-membered aromatic rings having the nitrogen atom of at least one of the carboxamide groups bound to a carbon atom of a hydrocarbon radical substituted by carboxyl groups with the substituted hydrocarbon radical bound to the nitrogen atom of the carboxamide group by an acyclic carbon atom of an acyclic saturated carbon skeleton
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AU2022296767A 2021-06-21 2022-06-21 Phenyl pyrrole aminoguanidine salts and formulations Pending AU2022296767A1 (en)

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EP21180708 2021-06-21
EP21180708.6 2021-06-21
EP21180702.9 2021-06-21
EP21180702 2021-06-21
EP21209855 2021-11-23
EP21209855.2 2021-11-23
PCT/EP2022/066906 WO2022268825A1 (en) 2021-06-21 2022-06-21 Phenyl pyrrole aminoguanidine salts and formulations

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US (3) US20230271922A9 (https=)
EP (3) EP4359076B1 (https=)
JP (2) JP2024523459A (https=)
KR (2) KR20240024818A (https=)
AU (2) AU2022296767A1 (https=)
BR (1) BR112023026909A2 (https=)
CA (2) CA3220753A1 (https=)
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IL (2) IL309102A (https=)
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CN120617247A (zh) * 2020-03-31 2025-09-12 西奈克制药有限公司 症状性病毒性疾病的治疗
EP4359076B1 (en) * 2021-06-21 2025-08-06 SynAct Pharma ApS Phenyl pyrrole aminoguanidine salts and formulations
WO2023218048A1 (en) * 2022-05-12 2023-11-16 Synact Pharma Aps Resomelagon and its derivatives for the treatment of cardiovascular disease, hypertension and atherosclerosis
CN120584099A (zh) * 2022-12-21 2025-09-02 西奈克制药有限公司 苯基吡咯肼甲脒化合物的多晶型物
WO2025124760A1 (en) 2023-12-11 2025-06-19 Synact Pharma Aps Treatment of subpopulation of patients with rheumatoid arthritis

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