JP2024009799A5 - - Google Patents
Info
- Publication number
- JP2024009799A5 JP2024009799A5 JP2023147032A JP2023147032A JP2024009799A5 JP 2024009799 A5 JP2024009799 A5 JP 2024009799A5 JP 2023147032 A JP2023147032 A JP 2023147032A JP 2023147032 A JP2023147032 A JP 2023147032A JP 2024009799 A5 JP2024009799 A5 JP 2024009799A5
- Authority
- JP
- Japan
- Prior art keywords
- mpges
- chr
- inhibitor
- nhc
- absent
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
Applications Claiming Priority (4)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| EP17203033.0 | 2017-11-22 | ||
| EP17203033 | 2017-11-22 | ||
| PCT/EP2018/082146 WO2019101826A1 (en) | 2017-11-22 | 2018-11-22 | Compounds as mpges-1 inhibitors |
| JP2020526121A JP7754623B2 (ja) | 2017-11-22 | 2018-11-22 | ｍＰＧＥＳ－１阻害剤としての化合物 |
Related Parent Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2020526121A Division JP7754623B2 (ja) | 2017-11-22 | 2018-11-22 | ｍＰＧＥＳ－１阻害剤としての化合物 |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JP2024009799A JP2024009799A (ja) | 2024-01-23 |
| JP2024009799A5 true JP2024009799A5 (https=) | 2025-12-18 |
Family
ID=60450482
Family Applications (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2020526121A Active JP7754623B2 (ja) | 2017-11-22 | 2018-11-22 | ｍＰＧＥＳ－１阻害剤としての化合物 |
| JP2023147032A Pending JP2024009799A (ja) | 2017-11-22 | 2023-09-11 | ｍＰＧＥＳ－１阻害剤としての化合物 |
Family Applications Before (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2020526121A Active JP7754623B2 (ja) | 2017-11-22 | 2018-11-22 | ｍＰＧＥＳ－１阻害剤としての化合物 |
Country Status (16)
| Country | Link |
|---|---|
| US (1) | US11672787B2 (https=) |
| EP (1) | EP3713564B1 (https=) |
| JP (2) | JP7754623B2 (https=) |
| KR (2) | KR20200090818A (https=) |
| CN (1) | CN111417393A (https=) |
| AU (1) | AU2018371153B2 (https=) |
| BR (1) | BR112020010089A2 (https=) |
| CA (1) | CA3079483A1 (https=) |
| ES (1) | ES2963906T3 (https=) |
| IL (1) | IL274821A (https=) |
| MX (1) | MX2020005238A (https=) |
| MY (1) | MY207603A (https=) |
| PL (1) | PL3713564T3 (https=) |
| SG (1) | SG11202003743SA (https=) |
| WO (1) | WO2019101826A1 (https=) |
| ZA (1) | ZA202002103B (https=) |
Families Citing this family (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| ES2959243T3 (es) * | 2017-04-05 | 2024-02-22 | Khondrion Ip B V | Nuevo tratamiento de enfermedades mitocondriales |
| NL2024431B1 (en) | 2019-12-11 | 2021-09-07 | Sulfateq Bv | Compounds for treatment of alzheimer’s disease |
| NL2025730B1 (en) * | 2020-06-02 | 2022-01-20 | Sulfateq Bv | Compounds for treatment of sepsis |
| WO2025242849A1 (en) * | 2024-05-24 | 2025-11-27 | Khondrion Ip B.V. | Chromanyl derivatives for use in the treatment of bone disorders |
Family Cites Families (28)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JPH02250831A (ja) | 1989-03-23 | 1990-10-08 | Kuraray Co Ltd | ３，４―ジヒドロ―２ｈ―ベンゾピラン誘導体及びそれを有効成分とする抗消化性潰瘍剤 |
| JP5086809B2 (ja) | 2004-12-17 | 2012-11-28 | メルク カナダ インコーポレイテッド | ｍＰＧＥＳ−１阻害剤としての２−（フェニルまたはヘテロ環式）−１Ｈ−フェナントロ［９，１０−ｄ］イミダゾール |
| US7442716B2 (en) | 2004-12-17 | 2008-10-28 | Merck Frosst Canada Ltd. | 2-(phenyl or heterocyclic)-1H-phenantrho[9,10-d]imidazoles as mPGES-1 inhibitors |
| DE102006053475A1 (de) | 2006-11-14 | 2008-06-19 | Eberhard-Karls-Universität Tübingen | Zubereitungen zur Hemmung der Prostaglandin E2 Synthese |
| DE102006058450A1 (de) | 2006-12-12 | 2008-06-19 | Eberhard-Karls-Universität Tübingen | Zubereitungen zur Hemmung der Prostaglandin E2 Synthese |
| EA038941B1 (ru) * | 2007-11-06 | 2021-11-12 | ПиТиСи ТЕРАПЬЮТИКС, ИНК. | ПРОИЗВОДНЫЕ 4-(п-ХИНОНИЛ)-2-ГИДРОКСИБУТАНАМИДА ДЛЯ ЛЕЧЕНИЯ МИТОХОНДРИАЛЬНЫХ ЗАБОЛЕВАНИЙ |
| WO2009130242A1 (en) | 2008-04-23 | 2009-10-29 | Novasaid Ab | Low molecular weight derivatives and use thereof in treatment of prostaglandin e synthase related diseases |
| DE102008027331A1 (de) | 2008-06-07 | 2009-12-10 | Friedrich-Alexander-Universität Erlangen-Nürnberg | Verwendung von Indol-3-carbonsäureestern zur Hemmung der mikrosomalen Prostaglandin E2 Synthase |
| UY32138A (es) | 2008-09-25 | 2010-04-30 | Boehringer Ingelheim Int | Amidas sustituidas del ácido 2-(2,6-dicloro-fenilamino)-6-fluoro-1-metil-1h-bencimidazol-5-carboxílico y sus sales farmacéuticamente aceptables |
| UY32470A (es) | 2009-03-05 | 2010-10-29 | Boehringer Ingelheim Int | Derivados de 2-{2-cloro-5-[(sustituido) metil]fenilamino} -1-metil]fenilamino}-1-metilbencimidazol-5-carboxamidas-n-(sustituidas) y sus sales fisiológicamente aceptables, composiciones conteniéndolos y aplicaciones |
| WO2010127152A2 (en) | 2009-04-29 | 2010-11-04 | Irm Llc | Compounds and compositions as microsomal prostaglandin e synthase-1 inhibitors |
| WO2011023812A1 (en) | 2009-08-27 | 2011-03-03 | Novasaid Ab | Microsomal prostaglandin e synthase-1 (mpges1) inhibitors |
| TW201305178A (zh) | 2010-10-29 | 2013-02-01 | Glenmark Pharmaceuticals Sa | 作為ｍＰＧＥＳ－１抑制物的三環化合物 |
| US8466186B2 (en) | 2010-12-10 | 2013-06-18 | Boehringer Ingelheim International Gmbh | Compounds |
| WO2012110860A1 (en) | 2011-02-17 | 2012-08-23 | Glenmark Pharmaceuticals S.A. | TRICYCLIC COMPOUNDS AS mPGES-1 INHIBITORS |
| WO2013038308A1 (en) | 2011-09-15 | 2013-03-21 | Glenmark Pharmaceuticals S.A. | SUBSTITUTED BICYCLIC HETEROARYL COMPOUNDS AS mPGES-1 INHIBITORS |
| WO2013072825A1 (en) | 2011-11-16 | 2013-05-23 | Glenmark Pharmaceuticals S.A. | Phtalazinone derivatives as mpegs -1 inhibitors |
| AR089939A1 (es) | 2012-02-09 | 2014-10-01 | Glenmark Pharmaceuticals Sa | COMPUESTOS BICICLICOS COMO INHIBIDORES DE mPGES-1 |
| WO2013153535A1 (en) | 2012-04-13 | 2013-10-17 | Glenmark Pharmaceuticals S.A. | TRICYCLIC COMPOUNDS AS mPGES-1 INHIBITORS |
| KR102137450B1 (ko) | 2012-07-12 | 2020-07-27 | 콘드리온 아이피 비.브이. | 미토콘드리아 질환을 치료하기 위한 크로마닐 유도체 |
| HRP20170532T4 (hr) * | 2012-07-12 | 2019-12-27 | Khondrion Ip B.V. | Derivati kromanila za liječenje mitohondrijske bolesti |
| NL2010010C2 (en) | 2012-12-19 | 2014-06-23 | Sulfateq B V | Compounds for protection of cells. |
| US10081629B2 (en) | 2014-04-14 | 2018-09-25 | Jiangsu Hengrui Medicine Co., Ltd. | Amide derivatives and pharmaceutically acceptable salts thereof, preparation method thereof and medicinal application thereof |
| NL2013012B1 (en) * | 2014-06-17 | 2016-07-05 | Sulfateq Bv | Compounds for the treatment of chronic obstructive airway diseases. |
| MX388654B (es) | 2015-05-22 | 2025-03-20 | Sulfateq Bv | Derivados de cromano y uso de los mismos en el tratamiento de daño en un órgano diabético, tal como un riñón. |
| US10815211B2 (en) | 2015-10-08 | 2020-10-27 | Khondrion Ip B.V. | Compounds for treating mitochondrial disease |
| ES2959243T3 (es) * | 2017-04-05 | 2024-02-22 | Khondrion Ip B V | Nuevo tratamiento de enfermedades mitocondriales |
| KR102782169B1 (ko) * | 2017-11-22 | 2025-03-17 | 콘드리온 아이피 비.브이. | 우울증 및 편두통 치료용 신규 화합물 |
-
2018
- 2018-11-22 SG SG11202003743SA patent/SG11202003743SA/en unknown
- 2018-11-22 BR BR112020010089-7A patent/BR112020010089A2/pt unknown
- 2018-11-22 PL PL18808288.7T patent/PL3713564T3/pl unknown
- 2018-11-22 WO PCT/EP2018/082146 patent/WO2019101826A1/en not_active Ceased
- 2018-11-22 KR KR1020207017202A patent/KR20200090818A/ko not_active Ceased
- 2018-11-22 AU AU2018371153A patent/AU2018371153B2/en active Active
- 2018-11-22 MY MYPI2020002221A patent/MY207603A/en unknown
- 2018-11-22 ES ES18808288T patent/ES2963906T3/es active Active
- 2018-11-22 KR KR1020257022058A patent/KR20250109241A/ko active Pending
- 2018-11-22 JP JP2020526121A patent/JP7754623B2/ja active Active
- 2018-11-22 EP EP18808288.7A patent/EP3713564B1/en active Active
- 2018-11-22 CA CA3079483A patent/CA3079483A1/en active Pending
- 2018-11-22 MX MX2020005238A patent/MX2020005238A/es unknown
- 2018-11-22 US US16/765,169 patent/US11672787B2/en active Active
- 2018-11-22 CN CN201880075549.3A patent/CN111417393A/zh active Pending
-
2020
- 2020-05-04 ZA ZA2020/02103A patent/ZA202002103B/en unknown
- 2020-05-20 IL IL274821A patent/IL274821A/en unknown
-
2023
- 2023-09-11 JP JP2023147032A patent/JP2024009799A/ja active Pending