|
US3845770A
(en)
|
1972-06-05 |
1974-11-05 |
Alza Corp |
Osmatic dispensing device for releasing beneficial agent
|
|
US4326525A
(en)
|
1980-10-14 |
1982-04-27 |
Alza Corporation |
Osmotic device that improves delivery properties of agent in situ
|
|
US4675189A
(en)
|
1980-11-18 |
1987-06-23 |
Syntex (U.S.A.) Inc. |
Microencapsulation of water soluble active polypeptides
|
|
US4723027A
(en)
|
1982-11-22 |
1988-02-02 |
E. I. Du Pont De Nemours And Company |
Preparation of optically active alpha-hydroxynitriles
|
|
ZA837994B
(en)
|
1982-11-22 |
1984-06-27 |
Shell Oil Co |
Process for the preparation of optically-active cyanomethyl esters
|
|
JPS60100516A
(ja)
|
1983-11-04 |
1985-06-04 |
Takeda Chem Ind Ltd |
徐放型マイクロカプセルの製造法
|
|
US5364620A
(en)
|
1983-12-22 |
1994-11-15 |
Elan Corporation, Plc |
Controlled absorption diltiazem formulation for once daily administration
|
|
CA1256638A
(en)
|
1984-07-06 |
1989-06-27 |
Motoaki Tanaka |
Polymer and its production
|
|
JP2551756B2
(ja)
|
1985-05-07 |
1996-11-06 |
武田薬品工業株式会社 |
ポリオキシカルボン酸エステルおよびその製造法
|
|
US5023252A
(en)
|
1985-12-04 |
1991-06-11 |
Conrex Pharmaceutical Corporation |
Transdermal and trans-membrane delivery of drugs
|
|
US4741897A
(en)
|
1986-07-08 |
1988-05-03 |
Baxter Travenol |
Thyroxine analogs and reagents for thyroid hormone assays
|
|
US5001139A
(en)
|
1987-06-12 |
1991-03-19 |
American Cyanamid Company |
Enchancers for the transdermal flux of nivadipine
|
|
US4992445A
(en)
|
1987-06-12 |
1991-02-12 |
American Cyanamid Co. |
Transdermal delivery of pharmaceuticals
|
|
DE69333894D1
(de)
|
1992-04-22 |
2005-12-01 |
Ligand Pharm Inc |
Verbindungen mit Retinoid x rezeptorselektivität
|
|
DE4320444A1
(de)
|
1993-06-21 |
1994-12-22 |
Agfa Gevaert Ag |
Farbfotografisches Aufzeichnungsmaterial
|
|
JP2000502086A
(ja)
|
1995-12-13 |
2000-02-22 |
ザ リージェンツ オブ ザ ユニバーシティ オブ カリフォルニア |
核レセプターのリガンドおよびリガンド結合ドメイン
|
|
JPH09301917A
(ja)
|
1996-05-08 |
1997-11-25 |
Koichi Shudo |
甲状腺ホルモン作用性化合物
|
|
CA2260992C
(en)
|
1996-08-20 |
2004-03-09 |
The Regents Of The University Of California |
Eye treatments using synthetic thyroid hormone compositions
|
|
US5883294A
(en)
*
|
1997-06-18 |
1999-03-16 |
The Regeants Of The University Of California |
Selective thyroid hormone analogs
|
|
GB9713739D0
(en)
|
1997-06-27 |
1997-09-03 |
Karobio Ab |
Thyroid receptor ligands
|
|
JP2002519340A
(ja)
|
1998-06-30 |
2002-07-02 |
ザ リージェンツ オブ ザ ユニバーシティ オブ カリフォルニア |
甲状腺ホルモン類似体およびそれらの調製方法
|
|
GB9828442D0
(en)
|
1998-12-24 |
1999-02-17 |
Karobio Ab |
Novel thyroid receptor ligands and method II
|
|
EP1194422A1
(en)
|
1999-06-01 |
2002-04-10 |
University Of Texas Southwestern Medical Center |
Biaryl compounds
|
|
US6787652B1
(en)
|
1999-09-30 |
2004-09-07 |
Pfizer, Inc. |
6-Azauracil derivatives as thyroid receptor ligands
|
|
DE60020786T2
(de)
|
1999-09-30 |
2006-03-23 |
Pfizer Products Inc., Groton |
6-Azauracilderivate als Liganden der Thyroidrezeptoren
|
|
US6436990B1
(en)
|
1999-10-27 |
2002-08-20 |
Nobex Corporation |
6-methoxy-2-naphthylacetic acid prodrugs
|
|
EP1127882A1
(en)
|
2000-01-25 |
2001-08-29 |
Pfizer Products Inc. |
Tetrazole compounds as thyroid receptor ligands
|
|
PL201790B1
(pl)
|
2000-02-17 |
2009-05-29 |
Bristol Myers Squibb Co |
Anilinopochodny ligand dla receptora tarczycy, jego zastosowanie i kompozycja farmaceutyczna
|
|
DE60115132T2
(de)
|
2000-04-21 |
2006-07-06 |
Pfizer Products Inc., Groton |
Thyroid-Rezeptorliganden
|
|
DE10024939A1
(de)
|
2000-05-19 |
2001-11-29 |
Bayer Ag |
Neue Diphenylmethanderivate für Arzneimittel
|
|
US6429223B1
(en)
|
2000-06-23 |
2002-08-06 |
Medinox, Inc. |
Modified forms of pharmacologically active agents and uses therefor
|
|
US7067532B2
(en)
|
2000-11-02 |
2006-06-27 |
Astrazeneca |
Substituted quinolines as antitumor agents
|
|
US6777442B2
(en)
|
2001-03-12 |
2004-08-17 |
Bayer Aktiengesellschaft |
Diphenyl derivatives
|
|
US20040267015A1
(en)
|
2001-04-05 |
2004-12-30 |
Ajita Bhat |
Peptide deformylase inhibitors
|
|
US7560433B2
(en)
|
2001-12-21 |
2009-07-14 |
Biotempt B.V. |
Treatment of multiple sclerosis (MS)
|
|
EP1497270A4
(en)
|
2002-03-27 |
2006-01-04 |
Smithkline Beecham Corp |
AMID COMPOUNDS AND METHOD FOR THEIR USE
|
|
US7302347B2
(en)
|
2002-12-10 |
2007-11-27 |
The Regents Of The University Of California |
Method for creating specific, high affinity nuclear receptor pharmaceuticals
|
|
US7321065B2
(en)
|
2003-04-18 |
2008-01-22 |
The Regents Of The University Of California |
Thyronamine derivatives and analogs and methods of use thereof
|
|
US20050203184A1
(en)
*
|
2003-09-10 |
2005-09-15 |
Petasis Nicos A. |
Benzo lipoxin analogues
|
|
US8071134B2
(en)
|
2003-09-15 |
2011-12-06 |
Ordway Research Institute, Inc. |
Thyroid hormone analogs and methods of use
|
|
EP2428516A1
(en)
|
2003-11-19 |
2012-03-14 |
Metabasis Therapeutics, Inc. |
Novel phosphorus-containing thyromimetics
|
|
WO2006012015A2
(en)
|
2004-06-29 |
2006-02-02 |
Oregon Health And Science University |
Methods and compositions for nerve regeneration
|
|
CA2583410A1
(en)
|
2004-09-15 |
2006-03-23 |
Albany College Of Pharmacy |
Thyroid hormone analogs for promoting angiogenesis
|
|
MX2007010076A
(es)
|
2005-02-17 |
2007-10-16 |
Astellas Pharma Inc |
Derivado de heterociclico-1-carboxilato que contiene nitrogeno no aromatico de piridilo.
|
|
CN101180097A
(zh)
|
2005-05-26 |
2008-05-14 |
症变治疗公司 |
新型含次膦酸的拟甲状腺素药
|
|
US20090232879A1
(en)
|
2005-05-26 |
2009-09-17 |
Metabasis Therapeutics, Inc. |
Thyromimetics for the Treatment of Fatty Liver Diseases
|
|
AU2006249347A1
(en)
|
2005-05-26 |
2006-11-30 |
Metabasis Therapeutics, Inc. |
Novel phosphorus-containing thyromimetics
|
|
RU2007148927A
(ru)
|
2005-05-26 |
2009-07-10 |
Метабэйзис Терапьютикс, Инк. (Us) |
Новые тиреомиметики, содержащие фосфиновую кислоту
|
|
GB0606212D0
(en)
*
|
2006-03-28 |
2006-05-10 |
Karobio Ab |
Pharmaceutical compositions
|
|
GB0608724D0
(en)
|
2006-05-03 |
2006-06-14 |
Karobio Ab |
Novel Pharmaceutical Compositions
|
|
WO2007132475A1
(en)
|
2006-05-15 |
2007-11-22 |
Cadila Healthcare Limited |
Selective tr-beta 1 agonist
|
|
NZ576424A
(en)
|
2006-10-20 |
2012-09-28 |
Biogen Idec Inc |
Treatment of demyelinating disorders with soluble lymphotoxin-beta-receptor
|
|
US8623861B2
(en)
|
2006-11-03 |
2014-01-07 |
Xin-Min Li |
Method of treating demyelination diseases
|
|
EP2656879B1
(en)
|
2006-12-10 |
2017-06-28 |
Chongxi Yu |
Transdermal delivery systems of beta-lactam antibiotics
|
|
AU2008226541B2
(en)
|
2007-03-09 |
2013-05-09 |
Chelsea Therapeutics, Inc. |
Droxidopa and pharmaceutical composition thereof for the treatment of fibromyalgia
|
|
FI20075245A0
(fi)
|
2007-04-11 |
2007-04-11 |
Markku Ahotupa |
Menetelmä oksidatiivisen metabolian arvioimiseksi
|
|
CA2693697C
(en)
|
2007-07-11 |
2017-07-25 |
Medicinova, Inc. |
Treatment of progressive neurodegenerative disease with ibudilast
|
|
WO2009097995A1
(de)
|
2008-02-07 |
2009-08-13 |
Sanofi-Aventis |
Neue phenyl-substituierte imidazolidine, verfahren zu deren herstellung, diese verbindungen enthaltende arzneimittel und deren verwendung
|
|
WO2009132050A2
(en)
|
2008-04-21 |
2009-10-29 |
Otonomy, Inc. |
Auris formulations for treating otic diseases and conditions
|
|
US8475804B2
(en)
|
2009-02-20 |
2013-07-02 |
U.S. Army Medical Research And Material Command |
Compositions and methods for treatment of filovirus-mediated diseases
|
|
WO2010148007A2
(en)
|
2009-06-17 |
2010-12-23 |
Ordway Research Institute, Inc. |
Nanoparticle and polymer formulations for thyroid hormone, analogs, antagonists, and formulations and uses thereof
|
|
WO2011041686A1
(en)
|
2009-10-01 |
2011-04-07 |
Mount Sinai School Of Medicine Of New York University |
Human type 1 taste receptor subunit 3 modulators and methods of using same
|
|
TW201221505A
(en)
|
2010-07-05 |
2012-06-01 |
Sanofi Sa |
Aryloxyalkylene-substituted hydroxyphenylhexynoic acids, process for preparation thereof and use thereof as a medicament
|
|
JP5847533B2
(ja)
|
2010-10-19 |
2016-01-27 |
田辺三菱製薬株式会社 |
新規甲状腺ホルモンβ受容体作動薬
|
|
US20140288077A1
(en)
|
2011-07-05 |
2014-09-25 |
St. Jude Children's Research Hospital |
Substituted 4-phenoxyphenol analogs as modulators of proliferating cell nuclear antigen activity
|
|
WO2013056232A2
(en)
|
2011-10-13 |
2013-04-18 |
Case Western Reserve University |
Rxr agonists compounds and methods
|
|
WO2014078892A1
(en)
|
2012-11-21 |
2014-05-30 |
Indyk Daniel |
A device and a test assembly for testing the integrity of a low voltage electrical network
|
|
MX376108B
(es)
*
|
2012-12-20 |
2025-03-07 |
Tempest Therapeutics Inc |
Compuestos de triazolona y usos de los mismos.
|
|
WO2014178892A1
(en)
|
2013-05-03 |
2014-11-06 |
Scanlan Thomas S |
Use of sobetirome in the treatment of x-linked adrenolenoleukodystrophy
|
|
MX2016000724A
(es)
|
2013-07-22 |
2016-04-13 |
Metabolic Solutions Dev Co Llc |
Compuestos de reserva de los receptores activados del proliferador de peroxisoma (ppar) para el tratamiento de enfermedades metabolicas.
|
|
US10258613B2
(en)
|
2014-02-05 |
2019-04-16 |
The Board Of Regents Of The University Of Oklahoma |
Compositions for treating retinal degeneration and methods of production and use thereof
|
|
EP3152190B1
(en)
|
2014-06-04 |
2024-07-31 |
Haro Pharmaceutical Inc. |
18-20 member bi-polycyclic compounds
|
|
WO2016057322A1
(en)
|
2014-10-08 |
2016-04-14 |
Salk Institute For Biological Studies |
Ppar agonists and methods of use thereof
|
|
JP6348229B2
(ja)
*
|
2014-10-21 |
2018-06-27 |
ユニバーシタット デ レス イレス バレアレス |
ヒドロキシ−トリグリセリドの合成方法、および疾患の予防および処置のためのその使用
|
|
MA41253A
(fr)
*
|
2014-12-23 |
2017-10-31 |
Proteostasis Therapeutics Inc |
Composés, compositions et procédés pour augmenter l'activité du cftr
|
|
PE20180021A1
(es)
|
2015-02-20 |
2018-01-09 |
Univ Oregon Health & Science |
Derivados de sobetiroma
|
|
JP6701225B2
(ja)
*
|
2015-03-09 |
2020-05-27 |
エフ．ホフマン−ラ ロシュ アーゲーＦ． Ｈｏｆｆｍａｎｎ−Ｌａ Ｒｏｃｈｅ Ａｋｔｉｅｎｇｅｓｅｌｌｓｃｈａｆｔ |
三環式ｄｌｋ阻害剤及びその使用
|
|
WO2017015360A1
(en)
|
2015-07-20 |
2017-01-26 |
Oregon Health & Science University |
Quinolone-3-diarylethers
|
|
US11872207B2
(en)
*
|
2015-12-24 |
2024-01-16 |
Mcmaster University |
Dronedarone and derivatives thereof for treating cancer
|
|
MX382313B
(es)
*
|
2016-05-18 |
2025-03-13 |
Univ Oregon Health & Science |
Derivados del sobetiroma.
|
|
US11325886B2
(en)
|
2016-08-12 |
2022-05-10 |
Oregon Health & Science University |
Amide compounds, pharmaceutical compositions thereof, and methods of using the same
|
|
WO2018208707A1
(en)
|
2017-05-08 |
2018-11-15 |
Neurovia, Inc. |
Methods and compositions for treating demyelinating diseases
|
|
MX2020008498A
(es)
|
2018-02-14 |
2020-09-25 |
Univ Oregon Health & Science |
Derivados de sobetirome.
|
|
CN111801013B
(zh)
|
2018-03-02 |
2021-12-24 |
俄勒冈健康科学大学 |
小分子核受体调节剂的酰胺前药
|
|
EP4775207A2
(en)
*
|
2018-12-05 |
2026-07-15 |
Viking Therapeutics, Inc. |
Compositions for the treatment of fibrosis
|
|
EP3894383A1
(en)
|
2018-12-12 |
2021-10-20 |
Autobahn Therapeutics, Inc. |
Novel thyromimetics
|
|
WO2020118564A1
(en)
|
2018-12-12 |
2020-06-18 |
Autobahn Therapeutics, Inc. |
Novel thyromimetics
|
|
CN119431265A
(zh)
|
2019-02-21 |
2025-02-14 |
南京瑞捷医药科技有限公司 |
一种作为甲状腺激素受体激动剂的化合物
|
|
CA3130371A1
(en)
|
2019-03-01 |
2020-09-10 |
Autobahn Therapeutics, Inc. |
Novel thyromimetics
|
|
WO2020227549A1
(en)
|
2019-05-08 |
2020-11-12 |
Aligos Therapeutics, Inc. |
MODULATORS OF THR-β AND METHODS OF USE THEREOF
|
|
CN115279359A
(zh)
|
2019-11-29 |
2022-11-01 |
速通医疗公司 |
新型拟甲状腺素药
|
|
MX2022008626A
(es)
|
2020-01-13 |
2022-08-22 |
Eccogene Shanghai Co Ltd |
Triazinonas sustituidas como agonistas del receptor de la hormona tiroidea.
|
|
WO2021247847A1
(en)
|
2020-06-03 |
2021-12-09 |
Autobahn Therapeutics, Inc. |
Isotopic thyromimetic compounds
|
|
EP4168384A4
(en)
|
2020-06-17 |
2024-07-10 |
Autobahn Therapeutics, Inc. |
THYROMIMETICS
|
|
WO2021257834A1
(en)
|
2020-06-17 |
2021-12-23 |
Autobahn Therapeutics, Inc. |
Thyromimetics
|
|
EP4167986A4
(en)
|
2020-06-17 |
2024-11-20 |
Autobahn Therapeutics, Inc. |
THYROMIMETICS
|