|
US2798053A
(en)
|
1952-09-03 |
1957-07-02 |
Goodrich Co B F |
Carboxylic polymers
|
|
US4183931A
(en)
|
1977-09-08 |
1980-01-15 |
Research Corporation |
2-Ketoalkyl-4(3H)-quinazolinones
|
|
EP0005501B1
(de)
|
1978-05-20 |
1981-11-25 |
Bayer Ag |
Heteroaryl-oxyessigsäureamide, Verfahren zu ihrer Herstellung und ihre Verwendung als Herbizide
|
|
US4461896A
(en)
|
1979-02-07 |
1984-07-24 |
Norwich Eaton Pharmaceuticals, Inc. |
1-[Acylthio) and (mercapto)-1-oxoalkyl]-1,2,3,4-tetrahydroquinoline-2-carboxylic acids
|
|
DE3018075A1
(de)
|
1980-05-10 |
1981-11-12 |
Bayer Ag, 5090 Leverkusen |
Mittel zur regulierung des pflanzenwachstums, deren herstellung und deren verwendung
|
|
JPS56158702A
(en)
|
1980-05-12 |
1981-12-07 |
Nippon Tokushu Noyaku Seizo Kk |
Herbicide
|
|
US4273927A
(en)
|
1980-08-14 |
1981-06-16 |
Morton-Norwich Products, Inc. |
Converting enzyme inhibitor
|
|
DE3038599A1
(de)
|
1980-10-13 |
1982-05-19 |
Bayer Ag, 5090 Leverkusen |
Substituierte benzazol-2-yl-oxyessigsaeureamide, verfahren zu ihrer herstellung und ihre verwendung als herbizide
|
|
DE3038652A1
(de)
|
1980-10-13 |
1982-05-19 |
Bayer Ag, 5090 Leverkusen |
5-chlor-benzoxazol-2-yl-oxyessigsaeureamide, verfahren zu ihrer herstellung und ihre verwendung als herbizide
|
|
US4509949A
(en)
|
1983-06-13 |
1985-04-09 |
The B. F. Goodrich Company |
Water thickening agents consisting of copolymers of crosslinked acrylic acids and esters
|
|
DE3418168A1
(de)
|
1984-05-16 |
1985-11-21 |
Bayer Ag, 5090 Leverkusen |
6-chlorbenzazolyloxyacetamide
|
|
DE3422861A1
(de)
|
1984-06-20 |
1986-01-02 |
Bayer Ag, 5090 Leverkusen |
Verfahren zur herstellung von heteroaryloxyacetamiden
|
|
US5087445A
(en)
|
1989-09-08 |
1992-02-11 |
Richardson-Vicks, Inc. |
Photoprotection compositions having reduced dermal irritation
|
|
US5075313A
(en)
|
1990-09-13 |
1991-12-24 |
Eli Lilly And Company |
3-aryl-4(3H)quinazolinone CCK antagonists and pharmaceutical formulations thereof
|
|
US5196427A
(en)
|
1990-09-13 |
1993-03-23 |
Eli Lilly And Company |
3-aryl-4(3H) quinazolinone CCK antagonists and pharmaceutical formulations thereof
|
|
DE4218433A1
(de)
|
1992-06-04 |
1993-12-09 |
Bayer Ag |
Fluorbenzoxazolyloxyacetamide
|
|
DE4219246A1
(de)
|
1992-06-12 |
1993-12-16 |
Bayer Ag |
Neue 2-(7-Chlor-2-benzoxazolyloxy)-acetamide
|
|
DE4230903A1
(de)
|
1992-09-16 |
1994-03-17 |
Bayer Ag |
Fluorbenzthiazolyloxyacetamide
|
|
FR2707639B1
(fr)
|
1993-06-30 |
1995-10-13 |
Pf Medicament |
Nouveaux composés indoliques dérivés d'arylamines comme ligands sélectifs des récepteurs 5HT1D et 5HT1B.
|
|
US5756502A
(en)
|
1994-08-08 |
1998-05-26 |
Warner-Lambert Company |
Quinazolinone derivatives as cholyecystokinin (CCK) ligands
|
|
DE19615262A1
(de)
|
1996-04-18 |
1997-10-23 |
Bayer Ag |
Heteroverknüpfte Phenylglycinolamide
|
|
CN1103772C
(zh)
|
1996-05-15 |
2003-03-26 |
辉瑞大药厂 |
新的2,3-二取代-4(3h)-喹唑啉酮类化合物
|
|
EP0807633B1
(en)
|
1996-05-15 |
2002-11-06 |
Pfizer Inc. |
Novel 2,3-disubstituted-(5,6)- heteroarylfused-pyrimidine-4-ones
|
|
TR199902094T2
(xx)
|
1997-02-28 |
1999-12-21 |
Prizer Products Inc. |
3-Heteroareil-4(3H)-kinazolinonlar�n atropizomerleri.
|
|
SK113299A3
(en)
|
1997-02-28 |
2001-05-10 |
Pfizer Prod Inc |
Atropisomers of 3-aryl-4(3h)-quinazolinones and their use as ampa-receptor antagonists
|
|
DE69809827D1
(de)
|
1997-03-31 |
2003-01-16 |
Korea Res Inst Chem Tech |
Chinolinische Sulfid-Derivate als NMDA Rezeptor-Antagonisten und Verfahren zu ihrer Herstellung
|
|
US6627755B1
(en)
|
1997-06-09 |
2003-09-30 |
Pfizer Inc |
Quinazolin-4-one AMPA antagonists
|
|
US6060479A
(en)
|
1997-06-09 |
2000-05-09 |
Pfizer Inc |
Quinazoline-4-one AMPA antagonists
|
|
US6323208B1
(en)
|
1997-09-05 |
2001-11-27 |
Pfizer Inc |
Atropisomers of 2,3-disubstituted-(5.6)-heteroaryl fused-pyrimidin-4-ones
|
|
IL125950A0
(en)
|
1997-09-05 |
1999-04-11 |
Pfizer Prod Inc |
Methods of administering ampa receptor antagonists to treat dyskinesias associated with dopamine agonist therapy
|
|
JPH11279158A
(ja)
|
1998-02-09 |
1999-10-12 |
Pfizer Prod Inc |
キナゾリン―4―オン誘導体の製造方法
|
|
JP4327915B2
(ja)
|
1998-03-30 |
2009-09-09 |
株式会社デ・ウエスタン・セラピテクス研究所 |
スルフォンアミド誘導体
|
|
JP4994552B2
(ja)
|
1999-09-16 |
2012-08-08 |
キュリス,インコーポレイテッド |
ヘッジホッグシグナル伝達経路のメディエーター、組成物及びそれらと関連する利用
|
|
US20030219806A1
(en)
|
2000-02-22 |
2003-11-27 |
Millennium Pharmaceuticals, Inc. |
Novel 18607, 15603, 69318, 12303, 48000, 52920, 5433, 38554, 57301, 58324, 55063, 52991, 59914, 59921 and 33751 molecules and uses therefor
|
|
AU2001270240A1
(en)
|
2000-06-26 |
2002-01-08 |
Millennium Pharmaceuticals, Inc. |
Human calcium channels (48000; 52920) and uses thereof
|
|
GB2372993A
(en)
|
2000-11-03 |
2002-09-11 |
Smithkline Beecham Plc |
Vanilloid Receptor 6
|
|
US20030027164A1
(en)
|
2000-12-01 |
2003-02-06 |
Gaughan Glen T. |
Novel human nucleic acid molecules and polypeptides encoding a novel human ion channel expressed in spinal cord and brain
|
|
EP1399558A2
(en)
|
2001-06-13 |
2004-03-24 |
Novartis AG |
Vanilloid receptor-related nucleic acids and polypeptides
|
|
US7053216B2
(en)
|
2001-11-19 |
2006-05-30 |
Iconix Pharmaceuticals, Inc. |
Modulators of Rho C activity
|
|
US20040110777A1
(en)
|
2001-12-03 |
2004-06-10 |
Annis Gary David |
Quinazolinones and pyridinylpyrimidinones for controlling invertebrate pests
|
|
US20040009537A1
(en)
|
2002-01-11 |
2004-01-15 |
Jack Roos |
Methods of modulating and of identifying agents that modulate intracellular calcium
|
|
TW200401770A
(en)
|
2002-06-18 |
2004-02-01 |
Sankyo Co |
Fused-ring pyrimidin-4(3H)-one derivatives, processes for the preparation and uses thereof
|
|
US6649638B1
(en)
|
2002-08-14 |
2003-11-18 |
Ppd Discovery, Inc. |
Prenylation inhibitors and methods of their synthesis and use
|
|
MXPA05004328A
(es)
|
2002-11-04 |
2005-08-02 |
Nps Pharma Inc |
Compuestos de quinazolinona como calciliticos.
|
|
DE10330157A1
(de)
|
2003-07-04 |
2005-02-03 |
Zf Friedrichshafen Ag |
Lastschaltgetriebe für Baumaschinen, insbesondere für Baggerlader und Telehandler
|
|
GB0317516D0
(en)
*
|
2003-07-25 |
2003-08-27 |
Pfizer Ltd |
Nicotinamide derivatives useful as PDE4 inhibitors
|
|
ATE532509T1
(de)
|
2003-09-11 |
2011-11-15 |
Tibotec Pharm Ltd |
Mittel zur hemmung des eintritts des hiv-virus
|
|
DE10351087A1
(de)
|
2003-10-31 |
2005-05-25 |
Bayer Technology Services Gmbh |
Feste Wirkstoff-Formulierung
|
|
CA2545725A1
(en)
|
2003-11-14 |
2005-06-02 |
Merck Sharp & Dohme Limited |
Bicyclic pyrimidin-4-(3h)-ones and analogues and derivatives thereof which modulate the function of the vanilloid-1 receptor (vr1)
|
|
EA010132B1
(ru)
*
|
2003-12-22 |
2008-06-30 |
Пфайзер Инк. |
Производные триазола в качестве антагонистов вазопрессина
|
|
EP1722783A4
(en)
|
2004-03-08 |
2009-08-12 |
Wyeth Corp |
MODULATORS OF THE ION CHANNEL FUNCTION
|
|
US20050202539A1
(en)
|
2004-03-11 |
2005-09-15 |
Hydra Biosciences |
System for screening eukaryotic membrane proteins
|
|
US20070265289A1
(en)
*
|
2004-04-15 |
2007-11-15 |
Yoshinori Okamoto |
2-Aminopyrimidine Derivative
|
|
EP1750715A1
(en)
|
2004-06-04 |
2007-02-14 |
Icos Corporation |
Methods for treating mast cell disorders
|
|
EP1790131B1
(en)
|
2004-09-09 |
2012-12-05 |
Avaya Inc. |
Methods of and systems for network traffic security
|
|
AR051596A1
(es)
|
2004-10-26 |
2007-01-24 |
Irm Llc |
Compuestos heterociclicos condensados nitrogenados como inhibidores de la actividad del receptor canabinoide 1; composiciones farmaceuticas que los contienen y su empleo en la preparacion de medicamentos para el tratamiento de trastornos alimentarios
|
|
GB0503646D0
(en)
*
|
2005-02-22 |
2005-03-30 |
Novartis Ag |
Organic compounds
|
|
EP2392328A1
(en)
|
2005-05-09 |
2011-12-07 |
Hydra Biosciences, Inc. |
Compounds for modulating TRPV3 Function
|
|
US8916550B2
(en)
|
2005-05-09 |
2014-12-23 |
Hydra Biosciences, Inc. |
Compounds for modulating TRPV3 function
|
|
GB0509573D0
(en)
|
2005-05-11 |
2005-06-15 |
Merck Sharp & Dohme |
Therapeutic compounds
|
|
US20090298856A1
(en)
|
2005-05-11 |
2009-12-03 |
Rebecca Elizabeth Brown |
2,3 Substituted fused bicyclic pyrimidin-4(3H)-ones modulating the function of the vanilliod-1receptor (VR1)
|
|
TW200726767A
(en)
*
|
2005-07-04 |
2007-07-16 |
Astrazeneca Ab |
Chemical compounds 2
|
|
JP5116687B2
(ja)
*
|
2005-11-02 |
2013-01-09 |
バイエル・ファルマ・アクチェンゲゼルシャフト |
がんおよび他の過剰増殖性疾患の処置のためのピロロ[2,1−f][1,2,4]トリアジン−4−イルアミンIGF−1Rキナーゼ阻害剤
|
|
US7893260B2
(en)
|
2005-11-04 |
2011-02-22 |
Hydra Biosciences, Inc. |
Substituted quinazolin-4-one compounds for antagonizing TRPV3 function
|
|
US7998980B2
(en)
|
2006-09-15 |
2011-08-16 |
Hydra Biosciences, Inc. |
Compounds for modulating TRPV3 function
|
|
WO2008140750A1
(en)
|
2007-05-10 |
2008-11-20 |
Hydra Biosciences Inc. |
Compounds for modulating trpv3 function
|
|
US20090306163A1
(en)
|
2008-06-10 |
2009-12-10 |
Pamela Renee Lipkin |
Topical compositions comprising imidazolidinedione analogs and their use to treat or prevent the appearance of skin wrinkling
|
|
KR101034300B1
(ko)
|
2008-12-02 |
2011-05-16 |
고려대학교 산학협력단 |
Trpv3 활성 억제 약물 및 이의 활용
|
|
US8318928B2
(en)
*
|
2008-12-15 |
2012-11-27 |
Glenmark Pharmaceuticals, S.A. |
Fused imidazole carboxamides as TRPV3 modulators
|
|
US8318759B2
(en)
*
|
2009-02-18 |
2012-11-27 |
Hoffmann-La Roche Inc. |
Pyrrolidine derivatives as NK3 receptor antagonists
|
|
US8614242B2
(en)
*
|
2010-10-21 |
2013-12-24 |
Bayer Intellectual Property Gmbh |
1-(heterocyclic carbonyl)-2-substituted pyrrolidines
|
|
EP2632551B1
(en)
*
|
2010-10-28 |
2016-07-06 |
Merck Sharp & Dohme Corp. |
Soluble guanylate cyclase activators
|
|
TW201336847A
(zh)
*
|
2012-02-07 |
2013-09-16 |
Taiho Pharmaceutical Co Ltd |
喹啉基吡咯并嘧啶化合物或其鹽
|
|
US20140018435A1
(en)
|
2012-06-06 |
2014-01-16 |
University Of Illinois Chicago |
Transdermal Delivery of Therapeutic Agents Using Poly (Amidoamine) Dendrimers
|
|
AR096151A1
(es)
*
|
2013-05-01 |
2015-12-09 |
Hoffmann La Roche |
Compuestos de biheteroarilo y usos de los mismos
|
|
WO2015070170A1
(en)
*
|
2013-11-08 |
2015-05-14 |
The Translational Genomics Research Institute |
Compounds for cognitive enhancement and methods of use thereof
|
|
US9562035B2
(en)
*
|
2013-12-03 |
2017-02-07 |
Janssen Pharmaceutica Nv |
Benzamide derivative useful as FASN inhibitors for the treatment of cancer
|
|
JP2017100948A
(ja)
*
|
2014-04-01 |
2017-06-08 |
大日本住友製薬株式会社 |
4−アリールイミダゾール誘導体
|
|
CN107912040B
(zh)
*
|
2014-10-10 |
2021-04-06 |
基因泰克公司 |
作为组蛋白脱甲基酶抑制剂的吡咯烷酰胺化合物
|
|
WO2016172631A2
(en)
*
|
2015-04-24 |
2016-10-27 |
President And Fellows Of Harvard College |
Substrate selective inhibitors of insulin-degrading enzyme (ide) and uses thereof
|
|
CN107417687A
(zh)
*
|
2016-05-24 |
2017-12-01 |
中国科学院上海药物研究所 |
五元杂环并[3,4‑d]哒嗪酮类化合物、其制备方法、药物组合物及其应用
|
|
CN108570038B
(zh)
|
2017-03-08 |
2021-09-28 |
中国科学院上海药物研究所 |
二氢喹喔啉类溴结构域识别蛋白抑制剂及制备方法和用途
|
|
WO2021154966A1
(en)
|
2020-01-29 |
2021-08-05 |
Kamari Pharma Ltd. |
Compounds and compositions for use in treating skin disorders
|
|
KR20250008740A
(ko)
*
|
2022-05-05 |
2025-01-15 |
카마리 파마 리미티드 |
피부 병태 및 이의 증상을 치료하는 방법
|