|
ES2232871T3
(es)
|
1996-07-03 |
2005-06-01 |
Sumitomo Pharmaceuticals Company, Limited |
Nuevos derivados de purina.
|
|
TW572758B
(en)
|
1997-12-22 |
2004-01-21 |
Sumitomo Pharma |
Type 2 helper T cell-selective immune response inhibitors comprising purine derivatives
|
|
US7157465B2
(en)
|
2001-04-17 |
2007-01-02 |
Dainippon Simitomo Pharma Co., Ltd. |
Adenine derivatives
|
|
WO2003037860A2
(en)
|
2001-10-30 |
2003-05-08 |
Conforma Therapeutics Corporation |
Purine analogs having hsp90-inhibiting activity
|
|
MXPA05003193A
(es)
|
2002-09-27 |
2005-06-08 |
Sumitomo Pharma |
Compuesto de adenina novedoso y uso del mismo.
|
|
JP2004137157A
(ja)
|
2002-10-16 |
2004-05-13 |
Sumitomo Pharmaceut Co Ltd |
新規アデニン誘導体を有効成分として含有する医薬
|
|
WO2005092892A1
(ja)
|
2004-03-26 |
2005-10-06 |
Dainippon Sumitomo Pharma Co., Ltd. |
８−オキソアデニン化合物
|
|
AU2006242920A1
(en)
|
2005-05-04 |
2006-11-09 |
Pfizer Limited |
2-amido-6-amino-8-oxopurine derivatives as Toll-Like receptor modulators for the treatment of cancer and viral infections, such as hepatitis C
|
|
JP4584335B2
(ja)
|
2005-09-02 |
2010-11-17 |
ファイザー・インク |
ヒドロキシ置換１ｈ−イミダゾピリジンおよび方法
|
|
JPWO2007034817A1
(ja)
|
2005-09-22 |
2009-03-26 |
大日本住友製薬株式会社 |
新規アデニン化合物
|
|
US20090105212A1
(en)
|
2005-09-22 |
2009-04-23 |
Dainippon Sumitomo Pharma Co., Ltd. a corporation of Japan |
Novel adenine compound
|
|
JP2009528989A
(ja)
|
2006-02-17 |
2009-08-13 |
ファイザー・リミテッド |
Ｔｌｒ７変調剤としての３−デアザプリン誘導体
|
|
CN101790380B
(zh)
|
2007-02-07 |
2013-07-10 |
加利福尼亚大学董事会 |
合成tlr激动剂的缀合物及其应用
|
|
AR065784A1
(es)
|
2007-03-20 |
2009-07-01 |
Dainippon Sumitomo Pharma Co |
Derivados de 8-oxo adenina,medicamentos que los contienen y usos como agentes terapeuticos para enfermedades alergicas, antivirales o antibacterianas.
|
|
EP2132207A2
(en)
|
2007-03-23 |
2009-12-16 |
Amgen Inc. |
Heterocyclic compounds and their uses
|
|
CA2691444C
(en)
|
2007-06-29 |
2016-06-14 |
Gilead Sciences, Inc. |
Purine derivatives and their use as modulators of toll-like receptor 7
|
|
ES2359123T3
(es)
|
2007-08-03 |
2011-05-18 |
Pfizer Limited |
Imidazopiridinonas.
|
|
RS53347B
(sr)
*
|
2008-12-09 |
2014-10-31 |
Gilead Sciences, Inc. |
Modulatori toll-sličnih receptora
|
|
KR20110117705A
(ko)
|
2009-02-11 |
2011-10-27 |
더 리전트 오브 더 유니버시티 오브 캘리포니아 |
톨-유사 수용체 조정제 및 질병의 치료
|
|
JP5694345B2
(ja)
|
2009-10-22 |
2015-04-01 |
ギリアード サイエンシーズ， インコーポレイテッド |
Ｔｏｌｌ様受容体の調節因子
|
|
US20120003298A1
(en)
|
2010-04-30 |
2012-01-05 |
Alcide Barberis |
Methods for inducing an immune response
|
|
AU2011247358B2
(en)
|
2010-04-30 |
2014-10-30 |
Urogen Pharma Ltd. |
Phospholipid drug analogs
|
|
JP2013525431A
(ja)
|
2010-04-30 |
2013-06-20 |
ザ リージェンツ オブ ザ ユニバーシティ オブ カリフォルニア |
合成ｔｌｒ７アゴニストのリン脂質結合体の使用
|
|
WO2012038058A1
(en)
|
2010-09-21 |
2012-03-29 |
Telormedix Sa |
Treatment of conditions by toll-like receptor modulators
|
|
TW201247706A
(en)
|
2011-03-08 |
2012-12-01 |
Baylor Res Inst |
Novel vaccine adjuvants based on targeting adjuvants to antibodies directly to antigen-presenting cells
|
|
JP6349256B2
(ja)
|
2011-11-09 |
2018-06-27 |
ヤンセン・サイエンシズ・アイルランド・ユーシー |
ウイルス感染の治療のためのプリン誘導体
|
|
EA035790B1
(ru)
|
2012-07-13 |
2020-08-11 |
Янссен Сайенсиз Айрлэнд Юси |
Макроциклические пурины для лечения вирусных инфекций
|
|
EA026354B1
(ru)
|
2012-08-24 |
2017-03-31 |
ГЛАКСОСМИТКЛАЙН ЭлЭлСи |
Пиразолопиримидиновые соединения
|
|
DK2906563T3
(en)
*
|
2012-10-10 |
2018-06-06 |
Janssen Sciences Ireland Uc |
PYRROLO [3,2-D] PYRIMIDINE DERIVATIVES FOR TREATING VIRUS INFECTIONS AND OTHER DISEASES
|
|
EP2732825B1
(en)
|
2012-11-19 |
2015-07-01 |
Invivogen |
Conjugates of a TLR7 and/or TLR8 agonist and a TLR2 agonist
|
|
US9295732B2
(en)
|
2013-02-22 |
2016-03-29 |
Invivogen |
Conjugated TLR7 and/or TLR8 and TLR2 polycationic agonists
|
|
CN110590809B
(zh)
|
2013-03-29 |
2022-04-19 |
爱尔兰詹森科学公司 |
用于治疗病毒感染的大环脱氮-嘌呤酮
|
|
PT3030563T
(pt)
|
2013-06-27 |
2017-11-15 |
Janssen Sciences Ireland Uc |
Derivados de pirrolo[3,2-d]pirimidina para o tratamento de infeções virais e outras doenças
|
|
EP3033089A2
(en)
|
2013-08-16 |
2016-06-22 |
The Regents of The University of California |
Uses of phospholipid conjugates of synthetic tlr7 agonists
|
|
WO2015036044A1
(en)
|
2013-09-13 |
2015-03-19 |
Telormedix Sa |
Cationic lipid vehicles for delivery of tlr7 agonists for specific targeting of human cd14+ monocytes in whole blood
|
|
PL3137470T3
(pl)
|
2014-05-01 |
2021-10-11 |
Novartis Ag |
Związki i kompozycje jako agonisty receptora toll-like 7
|
|
ES2908150T3
(es)
|
2014-05-01 |
2022-04-27 |
Novartis Ag |
Compuestos y composiciones como agonistas del receptor de tipo Toll 7
|
|
HRP20210927T1
(hr)
|
2014-08-15 |
2021-09-03 |
Chia Tai Tianqing Pharmaceutical Group Co., Ltd. |
Spojevi pirolopirimidina koje se koriste kao agonist tlr7
|
|
CN105732635A
(zh)
|
2014-12-29 |
2016-07-06 |
南京明德新药研发股份有限公司 |
一类Toll样受体7激动剂
|
|
PL3294740T3
(pl)
*
|
2015-05-08 |
2020-03-31 |
F. Hoffmann-La Roche Ag |
Nowe sulfonoimidoilopurynony i pochodne do leczenia i profilaktyki infekcji wirusowych
|
|
EP3368092B9
(en)
|
2015-10-29 |
2020-07-29 |
Novartis AG |
Antibody conjugates comprising toll-like receptor agonist
|
|
UA121345C2
(uk)
|
2015-11-05 |
2020-05-12 |
Чіа Тай Тяньцин Фармасьютікал Груп Ко., Лтд. |
7-(тіазол-5-іл)піролопіримідин як агоніст рецептора tlr7
|
|
JP6964072B2
(ja)
*
|
2016-04-26 |
2021-11-10 |
大日本住友製薬株式会社 |
置換プリン誘導体
|
|
CA3025746A1
(en)
|
2016-06-16 |
2017-12-21 |
Janssen Pharmaceutica Nv |
Azabenzimidazole derivatives as pi3k beta inhibitors
|
|
CR20190119A
(es)
*
|
2016-09-09 |
2019-06-03 |
Novartis Ag |
Compuestos y composiciones como inhibidores de los receptores endosomales tipo peaje
|
|
WO2018095426A1
(zh)
*
|
2016-11-28 |
2018-05-31 |
江苏恒瑞医药股份有限公司 |
吡唑并杂芳基类衍生物、其制备方法及其在医药上的应用
|
|
EP3603619B1
(en)
*
|
2017-03-29 |
2025-08-13 |
Sumitomo Pharma Co., Ltd. |
Vaccine adjuvant formulation
|
|
JP2020520379A
(ja)
*
|
2017-05-18 |
2020-07-09 |
江▲蘇▼恒瑞医▲薬▼股▲フン▼有限公司Ｊｉａｎｇｓｕ Ｈｅｎｇｒｕｉ Ｍｅｄｉｃｉｎｅ Ｃｏ．， Ｌｔｄ． |
ヘテロアリール−ピラゾール誘導体ならびにその調製方法および医学的適用
|
|
US10472361B2
(en)
*
|
2017-08-16 |
2019-11-12 |
Bristol-Myers Squibb Company |
Toll-like receptor 7 (TLR7) agonists having a benzotriazole moiety, conjugates thereof, and methods and uses therefor
|
|
US10508115B2
(en)
*
|
2017-08-16 |
2019-12-17 |
Bristol-Myers Squibb Company |
Toll-like receptor 7 (TLR7) agonists having heteroatom-linked aromatic moieties, conjugates thereof, and methods and uses therefor
|
|
US10487084B2
(en)
|
2017-08-16 |
2019-11-26 |
Bristol-Myers Squibb Company |
Toll-like receptor 7 (TLR7) agonists having a heterobiaryl moiety, conjugates thereof, and methods and uses therefor
|
|
US10457681B2
(en)
|
2017-08-16 |
2019-10-29 |
Bristol_Myers Squibb Company |
Toll-like receptor 7 (TLR7) agonists having a tricyclic moiety, conjugates thereof, and methods and uses therefor
|
|
US10494370B2
(en)
|
2017-08-16 |
2019-12-03 |
Bristol-Myers Squibb Company |
Toll-like receptor 7 (TLR7) agonists having a pyridine or pyrazine moiety, conjugates thereof, and methods and uses therefor
|
|
CN111757755A
(zh)
*
|
2017-12-21 |
2020-10-09 |
大日本住友制药株式会社 |
包含tlr7激动剂的组合药物
|
|
WO2019209811A1
(en)
|
2018-04-24 |
2019-10-31 |
Bristol-Myers Squibb Company |
Macrocyclic toll-like receptor 7 (tlr7) agonists
|
|
US11554120B2
(en)
*
|
2018-08-03 |
2023-01-17 |
Bristol-Myers Squibb Company |
1H-pyrazolo[4,3-d]pyrimidine compounds as toll-like receptor 7 (TLR7) agonists and methods and uses therefor
|
|
WO2021154667A1
(en)
*
|
2020-01-27 |
2021-08-05 |
Bristol-Myers Squibb Company |
C3-SUBSTITUTED 1H-PYRAZOLO[4,3-d]PYRIMIDINE COMPOUNDS AS TOLL-LIKE RECEPTOR 7 (TLR7) AGONISTS
|
|
EP4097105A1
(en)
*
|
2020-01-27 |
2022-12-07 |
Bristol-Myers Squibb Company |
1h-pyrazolo[4,3-d]pyrimidine compounds as toll-like receptor 7 (tlr7) agonists
|
|
CN115135655B
(zh)
*
|
2020-01-27 |
2024-07-02 |
百时美施贵宝公司 |
作为Toll样受体7(TLR7)激动剂的1H-吡唑并[4,3-d]嘧啶化合物
|
|
KR20220132601A
(ko)
*
|
2020-01-27 |
2022-09-30 |
브리스톨-마이어스 스큅 컴퍼니 |
톨-유사 수용체 7 (TLR7) 효능제로서의 1H-피라졸로[4,3-d]피리미딘 화합물
|
|
CN115279765B
(zh)
*
|
2020-01-27 |
2024-11-12 |
百时美施贵宝公司 |
作为Toll样受体7(TLR7)激动剂的1H-吡唑并[4,3-d]嘧啶化合物
|
|
EP4097100A1
(en)
*
|
2020-01-27 |
2022-12-07 |
Bristol-Myers Squibb Company |
1h-pyrazolo[4,3-d]pyrimidine compounds as toll-like receptor 7 (tlr7) agonists
|
|
EP4097104A1
(en)
*
|
2020-01-27 |
2022-12-07 |
Bristol-Myers Squibb Company |
1h-pyrazolo[4,3-d]pyrimidine compounds as toll-like receptor 7 (tlr7) agonists
|
|
WO2021154661A1
(en)
*
|
2020-01-27 |
2021-08-05 |
Bristol-Myers Squibb Company |
1H-PYRAZOLO[4,3-d]PYRIMIDINE COMPOUNDS AS TOLL-LIKE RECEPTOR 7 (TLR7) AGONISTS
|