PL3294740T3 - Nowe sulfonoimidoilopurynony i pochodne do leczenia i profilaktyki infekcji wirusowych - Google Patents
Nowe sulfonoimidoilopurynony i pochodne do leczenia i profilaktyki infekcji wirusowychInfo
- Publication number
- PL3294740T3 PL3294740T3 PL16720421T PL16720421T PL3294740T3 PL 3294740 T3 PL3294740 T3 PL 3294740T3 PL 16720421 T PL16720421 T PL 16720421T PL 16720421 T PL16720421 T PL 16720421T PL 3294740 T3 PL3294740 T3 PL 3294740T3
- Authority
- PL
- Poland
- Prior art keywords
- prophylaxis
- derivatives
- novel
- treatment
- virus infection
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D473/00—Heterocyclic compounds containing purine ring systems
- C07D473/02—Heterocyclic compounds containing purine ring systems with oxygen, sulphur, or nitrogen atoms directly attached in positions 2 and 6
- C07D473/24—Heterocyclic compounds containing purine ring systems with oxygen, sulphur, or nitrogen atoms directly attached in positions 2 and 6 one nitrogen and one sulfur atom
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
- A61K31/505—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
- A61K31/519—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim ortho- or peri-condensed with heterocyclic rings
- A61K31/52—Purines, e.g. adenine
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
- A61K31/505—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
- A61K31/519—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim ortho- or peri-condensed with heterocyclic rings
- A61K31/52—Purines, e.g. adenine
- A61K31/522—Purines, e.g. adenine having oxo groups directly attached to the heterocyclic ring, e.g. hypoxanthine, guanine, acyclovir
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/16—Drugs for disorders of the alimentary tract or the digestive system for liver or gallbladder disorders, e.g. hepatoprotective agents, cholagogues, litholytics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
- A61P31/20—Antivirals for DNA viruses
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Life Sciences & Earth Sciences (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Pharmacology & Pharmacy (AREA)
- Medicinal Chemistry (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Oncology (AREA)
- Communicable Diseases (AREA)
- Virology (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Epidemiology (AREA)
- Gastroenterology & Hepatology (AREA)
- Molecular Biology (AREA)
- Biotechnology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Applications Claiming Priority (4)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN2015078507 | 2015-05-08 | ||
| CN2016078785 | 2016-04-08 | ||
| EP16720421.3A EP3294740B1 (en) | 2015-05-08 | 2016-05-04 | Novel sulfonimidoylpurinone compounds and derivatives for the treatment and prophylaxis of virus infection |
| PCT/EP2016/059961 WO2016180695A1 (en) | 2015-05-08 | 2016-05-04 | Novel sulfonimidoylpurinone compounds and derivatives for the treatment and prophylaxis of virus infection |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| PL3294740T3 true PL3294740T3 (pl) | 2020-03-31 |
Family
ID=55910966
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| PL16720421T PL3294740T3 (pl) | 2015-05-08 | 2016-05-04 | Nowe sulfonoimidoilopurynony i pochodne do leczenia i profilaktyki infekcji wirusowych |
Country Status (33)
| Country | Link |
|---|---|
| US (3) | US9708325B2 (pl) |
| EP (1) | EP3294740B1 (pl) |
| JP (1) | JP6738352B2 (pl) |
| KR (1) | KR20180003612A (pl) |
| CN (1) | CN107580596B (pl) |
| AR (1) | AR104528A1 (pl) |
| AU (3) | AU2016260683B2 (pl) |
| BR (1) | BR112017023959B1 (pl) |
| CA (1) | CA2982704C (pl) |
| CL (1) | CL2017002745A1 (pl) |
| CO (1) | CO2017009994A2 (pl) |
| CR (1) | CR20170496A (pl) |
| DK (1) | DK3294740T3 (pl) |
| ES (1) | ES2753777T3 (pl) |
| HK (1) | HK1247925A1 (pl) |
| HR (1) | HRP20191942T1 (pl) |
| HU (1) | HUE045906T2 (pl) |
| IL (2) | IL254947B (pl) |
| LT (1) | LT3294740T (pl) |
| MX (2) | MX2017014033A (pl) |
| MY (1) | MY182353A (pl) |
| NZ (1) | NZ735648A (pl) |
| PE (1) | PE20171620A1 (pl) |
| PH (1) | PH12017502009A1 (pl) |
| PL (1) | PL3294740T3 (pl) |
| PT (1) | PT3294740T (pl) |
| RS (1) | RS59435B1 (pl) |
| RU (1) | RU2745269C2 (pl) |
| SG (1) | SG10202108841YA (pl) |
| SI (1) | SI3294740T1 (pl) |
| TW (2) | TWI706954B (pl) |
| UA (1) | UA120450C2 (pl) |
| WO (1) | WO2016180695A1 (pl) |
Families Citing this family (9)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DK3294740T3 (da) * | 2015-05-08 | 2019-11-04 | H Hoffmann La Roche Ag | Hidtil ukendte sulfonimidoylpurinonforbindelser og derivater til behandling og profylakse af virusinfektion |
| SI3504210T1 (sl) * | 2016-08-29 | 2021-08-31 | F. Hoffmann-La Roche Ag | 7-substituirane sulfonimidoilpurinonske spojine za zdravljenje virusne okužbe in zaščito pred njo |
| AU2017326400B2 (en) * | 2016-09-13 | 2023-03-30 | F. Hoffmann-La Roche Ag | Combined treatment with a TLR7 agonist and an HBV capsid assembly inhibitor |
| JP7328977B2 (ja) | 2018-02-12 | 2023-08-17 | エフ． ホフマン－ラ ロシュ アーゲー | ウイルス感染の処置および予防のための新規のスルホン化合物および誘導体 |
| CN111801100B (zh) * | 2018-02-28 | 2023-10-24 | 豪夫迈·罗氏有限公司 | 用于治疗和预防肝癌的7-取代的磺亚氨酰基嘌呤酮化合物和衍生物 |
| CN111072667A (zh) * | 2018-10-22 | 2020-04-28 | 罗欣药业(上海)有限公司 | 五元或六元杂环并嘧啶类化合物及其用途 |
| BR112021015832A2 (pt) * | 2019-02-12 | 2022-01-18 | Ambrx Inc | Composições que contêm conjugados de anticorpo-agonista de tlr, métodos e usos dos mesmos |
| CN114450280A (zh) | 2019-09-20 | 2022-05-06 | 先正达农作物保护股份公司 | 具有含硫和亚砜亚胺取代基的杀有害生物活性杂环衍生物 |
| WO2024013205A1 (en) | 2022-07-14 | 2024-01-18 | F. Hoffmann-La Roche Ag | Phosphorylpurinone compounds for the treatment of cancer |
Family Cites Families (11)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JP4189048B2 (ja) | 1997-12-26 | 2008-12-03 | 大日本住友製薬株式会社 | 複素環化合物 |
| WO2006117670A1 (en) | 2005-05-04 | 2006-11-09 | Pfizer Limited | 2-amido-6-amino-8-oxopurine derivatives as toll-like receptor modulators for the treatment of cancer and viral infections, such as hepatitis c |
| CN101239980B (zh) | 2008-02-18 | 2011-06-22 | 靳广毅 | 免疫受体调节剂偶联体前体和偶联体及其应用 |
| AU2009333559B2 (en) * | 2008-12-09 | 2015-03-12 | Gilead Sciences, Inc. | Modulators of toll-like receptors |
| US20110150836A1 (en) | 2009-12-22 | 2011-06-23 | Gilead Sciences, Inc. | Methods of treating hbv and hcv infection |
| TWI555737B (zh) * | 2011-05-24 | 2016-11-01 | 拜耳知識產權公司 | 含有硫醯亞胺基團之４－芳基－ｎ－苯基－１，３，５－三氮雜苯－２－胺 |
| BR122019020718B1 (pt) * | 2011-11-09 | 2021-07-06 | Janssen Sciences Ireland Uc | Derivados purínicos para o tratamento de infecções virais e composição farmacêutica que os compreende |
| SG11201508078XA (en) | 2013-03-29 | 2015-11-27 | Janssen Sciences Ireland Uc | Macrocyclic deaza-purinones for the treatment of viral infections |
| SG11201701169XA (en) | 2014-08-15 | 2017-03-30 | Chia Tai Tianqing Pharmaceutical Group Co Ltd | Pyrrolopyrimidine compounds used as tlr7 agonist |
| DK3294740T3 (da) * | 2015-05-08 | 2019-11-04 | H Hoffmann La Roche Ag | Hidtil ukendte sulfonimidoylpurinonforbindelser og derivater til behandling og profylakse af virusinfektion |
| SI3504210T1 (sl) * | 2016-08-29 | 2021-08-31 | F. Hoffmann-La Roche Ag | 7-substituirane sulfonimidoilpurinonske spojine za zdravljenje virusne okužbe in zaščito pred njo |
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2016
- 2016-05-04 DK DK16720421T patent/DK3294740T3/da active
- 2016-05-04 BR BR112017023959-0A patent/BR112017023959B1/pt active IP Right Grant
- 2016-05-04 AU AU2016260683A patent/AU2016260683B2/en active Active
- 2016-05-04 MX MX2017014033A patent/MX2017014033A/es active IP Right Grant
- 2016-05-04 MY MYPI2017704175A patent/MY182353A/en unknown
- 2016-05-04 LT LT16720421T patent/LT3294740T/lt unknown
- 2016-05-04 EP EP16720421.3A patent/EP3294740B1/en active Active
- 2016-05-04 CR CR20170496A patent/CR20170496A/es unknown
- 2016-05-04 RU RU2017142577A patent/RU2745269C2/ru active
- 2016-05-04 PE PE2017002102A patent/PE20171620A1/es unknown
- 2016-05-04 RS RSP20191351 patent/RS59435B1/sr unknown
- 2016-05-04 JP JP2017558397A patent/JP6738352B2/ja active Active
- 2016-05-04 CA CA2982704A patent/CA2982704C/en active Active
- 2016-05-04 NZ NZ735648A patent/NZ735648A/en unknown
- 2016-05-04 ES ES16720421T patent/ES2753777T3/es active Active
- 2016-05-04 SG SG10202108841YA patent/SG10202108841YA/en unknown
- 2016-05-04 HU HUE16720421A patent/HUE045906T2/hu unknown
- 2016-05-04 UA UAA201712023A patent/UA120450C2/uk unknown
- 2016-05-04 PT PT167204213T patent/PT3294740T/pt unknown
- 2016-05-04 KR KR1020177035298A patent/KR20180003612A/ko active IP Right Grant
- 2016-05-04 WO PCT/EP2016/059961 patent/WO2016180695A1/en active Application Filing
- 2016-05-04 SI SI201630473T patent/SI3294740T1/sl unknown
- 2016-05-04 PL PL16720421T patent/PL3294740T3/pl unknown
- 2016-05-04 CN CN201680026493.3A patent/CN107580596B/zh active Active
- 2016-05-04 MX MX2020010949A patent/MX2020010949A/es unknown
- 2016-05-05 AR ARP160101278A patent/AR104528A1/es unknown
- 2016-05-06 US US15/148,309 patent/US9708325B2/en active Active
- 2016-05-06 TW TW105114192A patent/TWI706954B/zh active
- 2016-05-06 TW TW109131169A patent/TWI768467B/zh active
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2017
- 2017-06-13 US US15/621,080 patent/US10399983B2/en active Active
- 2017-09-29 CO CONC2017/0009994A patent/CO2017009994A2/es unknown
- 2017-10-09 IL IL254947A patent/IL254947B/en active IP Right Grant
- 2017-10-30 CL CL2017002745A patent/CL2017002745A1/es unknown
- 2017-11-03 PH PH12017502009A patent/PH12017502009A1/en unknown
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2018
- 2018-06-07 HK HK18107428.7A patent/HK1247925A1/zh unknown
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2019
- 2019-08-02 US US16/530,229 patent/US11242345B2/en active Active
- 2019-10-24 HR HRP20191942TT patent/HRP20191942T1/hr unknown
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2020
- 2020-10-14 AU AU2020256348A patent/AU2020256348B2/en active Active
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2021
- 2021-02-09 IL IL280769A patent/IL280769B2/en unknown
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2022
- 2022-06-29 AU AU2022204666A patent/AU2022204666A1/en active Pending
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