JP2023500895A5 - - Google Patents

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Publication number
JP2023500895A5
JP2023500895A5 JP2022526028A JP2022526028A JP2023500895A5 JP 2023500895 A5 JP2023500895 A5 JP 2023500895A5 JP 2022526028 A JP2022526028 A JP 2022526028A JP 2022526028 A JP2022526028 A JP 2022526028A JP 2023500895 A5 JP2023500895 A5 JP 2023500895A5
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Japan
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group
ala
glu
compound
thr
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JP2022526028A
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Japanese (ja)
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JP2023500895A (ja
JP7821393B2 (ja
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Priority claimed from PCT/EP2020/081513 external-priority patent/WO2021094259A1/en
Publication of JP2023500895A publication Critical patent/JP2023500895A/ja
Publication of JP2023500895A5 publication Critical patent/JP2023500895A5/ja
Priority to JP2025178353A priority Critical patent/JP2026026081A/ja
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Publication of JP7821393B2 publication Critical patent/JP7821393B2/ja
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JP2022526028A 2019-11-11 2020-11-09 Ｎｐｙ２受容体アゴニスト Active JP7821393B2 (ja)

Priority Applications (1)

Application Number Priority Date Filing Date Title
JP2025178353A JP2026026081A (ja) 2019-11-11 2025-10-23 Ｎｐｙ２受容体アゴニスト

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
EP19208394 2019-11-11
EP19208394.7 2019-11-11
PCT/EP2020/081513 WO2021094259A1 (en) 2019-11-11 2020-11-09 Npy2 receptor agonists

Related Child Applications (1)

Application Number Title Priority Date Filing Date
JP2025178353A Division JP2026026081A (ja) 2019-11-11 2025-10-23 Ｎｐｙ２受容体アゴニスト

Publications (3)

Publication Number Publication Date
JP2023500895A JP2023500895A (ja) 2023-01-11
JP2023500895A5 true JP2023500895A5 (https=) 2023-02-14
JP7821393B2 JP7821393B2 (ja) 2026-02-27

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ID=68531488

Family Applications (2)

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JP2022526028A Active JP7821393B2 (ja) 2019-11-11 2020-11-09 Ｎｐｙ２受容体アゴニスト
JP2025178353A Pending JP2026026081A (ja) 2019-11-11 2025-10-23 Ｎｐｙ２受容体アゴニスト

Family Applications After (1)

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JP2025178353A Pending JP2026026081A (ja) 2019-11-11 2025-10-23 Ｎｐｙ２受容体アゴニスト

Country Status (20)

Country Link
US (3) US20210139548A1 (https=)
EP (1) EP4058047A1 (https=)
JP (2) JP7821393B2 (https=)
KR (1) KR20220100925A (https=)
CN (1) CN114641303A (https=)
AR (1) AR120440A1 (https=)
AU (1) AU2020384729A1 (https=)
CA (1) CA3156452A1 (https=)
CL (1) CL2022001227A1 (https=)
CO (1) CO2022006046A2 (https=)
CR (1) CR20220206A (https=)
DO (1) DOP2022000097A (https=)
EC (1) ECSP22037660A (https=)
IL (1) IL292601A (https=)
JO (1) JOP20220110A1 (https=)
MX (1) MX2022005661A (https=)
PE (1) PE20221168A1 (https=)
PH (1) PH12022551101A1 (https=)
TW (1) TWI864155B (https=)
WO (1) WO2021094259A1 (https=)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CR20220206A (es) 2019-11-11 2022-06-16 Boehringer Ingelheim Int Agonistas del receptor npy2
JP7661478B2 (ja) * 2020-08-07 2025-04-14 ベーリンガー インゲルハイム インターナショナル ゲゼルシャフト ミット ベシュレンクテル ハフツング 可溶性ｎｐｙ２受容体アゴニスト
JP2025526148A (ja) * 2022-08-18 2025-08-07 ベーリンガー インゲルハイム インターナショナル ゲゼルシャフト ミット ベシュレンクテル ハフツング 長時間作用型ｇｌｐ－１／グルカゴン受容体アゴニスト及びｎｐｙ２受容体アゴニストを含む組合せ治療
CN120865433A (zh) * 2022-12-21 2025-10-31 勃林格殷格翰国际有限公司 Glp1/gip/npy2受体的三重激动剂
EP4670741A1 (en) 2023-04-28 2025-12-31 Pinotbio, Inc. ANTIBODY-DRUG CONJUGATE IN WHICH ONE OR MORE DRUG-BINDER CONJUGATES ARE LINKED TO AN ANTIBODY AND ITS PREPARATION METHOD

Family Cites Families (53)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2005053726A1 (en) 2003-11-25 2005-06-16 Bayer Pharmaceuticals Corporation Selective neuropeptide y2 receptor agonists
NZ579621A (en) 2004-02-11 2011-03-31 Amylin Pharmaceuticals Inc Hybrid polypeptides with selectable properties
EA011860B1 (ru) 2004-03-17 2009-06-30 7ТиЭм ФАРМА А/С Селективные агонисты рецептора y2 для терапевтического воздействия
WO2006049681A2 (en) 2004-08-30 2006-05-11 Bayer Pharmaceuticals Corporation Selective neuropeptide y2 receptor agonists
US8394765B2 (en) 2004-11-01 2013-03-12 Amylin Pharmaceuticals Llc Methods of treating obesity with two different anti-obesity agents
EP2360180A3 (en) 2004-12-13 2012-02-08 Amylin Pharmaceuticals Inc. Pancreatic polypeptide family motifs, polypeptides and methods comprising the same
CA2630649A1 (en) 2005-12-07 2007-06-14 F. Hoffmann-La Roche Ag Neuropeptide-2 receptor-agonists
CA2677932A1 (en) 2007-02-15 2008-08-21 Indiana University Research And Technology Corporation Glucagon/glp-1 receptor co-agonists
EP2158214B1 (en) 2007-06-15 2011-08-17 Zealand Pharma A/S Glucagon analogues
UA97707C2 (ru) 2007-11-14 2012-03-12 Амилин Фармасьютикалз, Инк. Способы лечения ожирения и заболеваний, расстройств, связанных с ожирением
FR2934058B1 (fr) 2008-07-15 2010-09-24 Centre Nat Rech Scient Dispositif de projection interferometrique a trois ouvertures pour produire une tache constituee de structures fines
EP2370462B1 (en) 2008-12-15 2014-07-16 Zealand Pharma A/S Glucagon analogues
JP5635531B2 (ja) 2008-12-15 2014-12-03 ジーランド ファーマ アクティーゼルスカブ グルカゴン類似体
ES2477880T3 (es) 2008-12-15 2014-07-18 Zealand Pharma A/S Análogos del glucagón
CN102282167B (zh) 2008-12-15 2014-08-13 西兰制药公司 胰高血糖素类似物
AU2010272944B2 (en) 2009-07-13 2015-11-19 Zealand Pharma A/S Acylated glucagon analogues
WO2011033068A1 (en) 2009-09-18 2011-03-24 Novo Nordisk A/S Long-acting y2 receptor agonists
EP2498800A1 (en) 2009-11-13 2012-09-19 Novo Nordisk A/S Long-acting y2 receptor agonists
CN102946875A (zh) 2010-05-05 2013-02-27 贝林格尔.英格海姆国际有限公司 组合疗法
UY33462A (es) 2010-06-23 2012-01-31 Zealand Pharma As Analogos de glucagon
US9169310B2 (en) 2010-06-24 2015-10-27 Zealand Pharma A/S Glucagon analogues
JP6121992B2 (ja) 2011-06-10 2017-04-26 ノヴォ ノルディスク アー／エス ポリペプチド
IN2014CN04401A (https=) 2011-12-23 2015-09-04 Zealand Pharma As
IN2014MN02304A (https=) 2012-05-03 2015-08-07 Zealand Pharma As
TWI608013B (zh) 2012-09-17 2017-12-11 西蘭製藥公司 升糖素類似物
AU2014261111B2 (en) 2013-05-02 2017-03-16 Glaxosmithkline Intellectual Property Development Limited Therapeutic peptides
AR097701A1 (es) 2013-09-19 2016-04-13 Zealand Pharma As Análogos de amilina
US9988429B2 (en) 2013-10-17 2018-06-05 Zealand Pharma A/S Glucagon analogues
PL3057984T3 (pl) 2013-10-17 2018-12-31 Zealand Pharma A/S Acylowane analogi glukagonu
CN105829339B (zh) 2013-11-06 2021-03-12 西兰制药公司 胰高血糖素-glp-1-gip三重激动剂化合物
CN105722854B (zh) 2013-11-14 2020-08-04 关键生物科学有限公司 用于治疗疾病和病症的降钙素模拟物
EP3068795B1 (en) * 2013-11-15 2019-03-06 Novo Nordisk A/S Hpyy(1-36) having a beta-homoarginine substitution at position 35
CN105722526B (zh) * 2013-11-15 2020-12-08 诺和诺德股份有限公司 选择性pyy化合物及其用途
BR112017019378A2 (pt) 2015-03-18 2019-02-19 Zealand Pharma A/S análogos de amilina
DK3283507T3 (da) 2015-04-16 2020-01-02 Zealand Pharma As Acyleret glucagonanalog
WO2016198624A1 (en) 2015-06-12 2016-12-15 Sanofi Exendin-4 derivatives as trigonal glp-1/glucagon/gip receptor agonists
TWI694082B (zh) * 2015-06-12 2020-05-21 丹麥商諾佛 儂迪克股份有限公司 選擇性ｐｙｙ化合物及其用途
SG11201805586SA (en) 2015-12-31 2018-07-30 Hanmi Pharmaceutical Co Ltd Triple glucagon/glp-1/gip receptor agonist
EP3452088A4 (en) 2016-05-03 2020-04-15 The Scripps Research Institute TRKB AGONIST ANTIBODIES FOR THE TREATMENT OF NEURODEGENERATIVE DISEASES
US10071140B2 (en) 2016-09-09 2018-09-11 Zealand Pharma A/S Amylin analogues
JOP20190095A1 (ar) 2016-10-27 2019-04-28 Janssen Pharmaceutica Nv مركبات ببتيد تيروسين-تيروسين الحلقية كمعدلات لمستقبلات الببتيد العصبي y
TW201833131A (zh) 2016-12-02 2018-09-16 法商賽諾菲公司 作為胜肽類ｇｌｐ１／升糖素／ｇｉｐ受體促效劑之新化合物
AR110300A1 (es) 2016-12-02 2019-03-13 Sanofi Sa Compuestos como agonistas peptídicos trigonales de los receptores de glp1 / glucagón / gip
CN108289005B (zh) 2017-01-09 2021-06-29 中兴通讯股份有限公司 信令发送、接收方法及装置
GB201704429D0 (en) 2017-03-21 2017-05-03 Keybioscience Ag Calcitonin mimetics for treating diseases and disorders
US10793634B2 (en) 2017-06-09 2020-10-06 Boehringer Ingelheim International Gmbh Anti-TrkB antibodies
GB201720188D0 (en) 2017-12-04 2018-01-17 Imperial Innovations Ltd Analogues of PYY
US10581312B2 (en) 2017-12-29 2020-03-03 Texas Instruments Incorporated Multilevel converter using node voltage track and control
WO2019147650A1 (en) 2018-01-23 2019-08-01 Gila Therapeutics, Inc. Peptide yy pharmaceutical formulations, compositions, and methods
TWI847981B (zh) 2018-04-25 2024-07-11 比利時商健生藥品公司 類升糖素肽1 (glp-1)融合肽偶合環狀酪酪肽接合物及其用途
TW202535916A (zh) * 2018-11-01 2025-09-16 美商美國禮來大藥廠 蛋白質酪胺酸-酪胺酸類似物及其使用方法
CR20220206A (es) 2019-11-11 2022-06-16 Boehringer Ingelheim Int Agonistas del receptor npy2
JP7661478B2 (ja) 2020-08-07 2025-04-14 ベーリンガー インゲルハイム インターナショナル ゲゼルシャフト ミット ベシュレンクテル ハフツング 可溶性ｎｐｙ２受容体アゴニスト

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