AU2020384729A1 - NPY2 receptor agonists - Google Patents

NPY2 receptor agonists Download PDF

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Publication number
AU2020384729A1
AU2020384729A1 AU2020384729A AU2020384729A AU2020384729A1 AU 2020384729 A1 AU2020384729 A1 AU 2020384729A1 AU 2020384729 A AU2020384729 A AU 2020384729A AU 2020384729 A AU2020384729 A AU 2020384729A AU 2020384729 A1 AU2020384729 A1 AU 2020384729A1
Authority
AU
Australia
Prior art keywords
ethoxy
group
hpyy
val
glu
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
AU2020384729A
Other languages
English (en)
Inventor
Albert Brennauer
Peter Wilhelm Haebel
Charlotte Stahl MADSEN
Søren Ljungberg Pedersen
Stefan Peters
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Boehringer Ingelheim International GmbH
Original Assignee
Boehringer Ingelheim International GmbH
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Boehringer Ingelheim International GmbH filed Critical Boehringer Ingelheim International GmbH
Publication of AU2020384729A1 publication Critical patent/AU2020384729A1/en
Pending legal-status Critical Current

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Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • A61K38/22—Hormones
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/46—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates
    • C07K14/47—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • A61K38/22—Hormones
    • A61K38/2271—Neuropeptide Y

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Organic Chemistry (AREA)
  • Zoology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Engineering & Computer Science (AREA)
  • Epidemiology (AREA)
  • Immunology (AREA)
  • Endocrinology (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • Molecular Biology (AREA)
  • Toxicology (AREA)
  • Genetics & Genomics (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Hematology (AREA)
  • Obesity (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Diabetes (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Peptides Or Proteins (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
AU2020384729A 2019-11-11 2020-11-09 NPY2 receptor agonists Pending AU2020384729A1 (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
EP19208394 2019-11-11
EP19208394.7 2019-11-11
PCT/EP2020/081513 WO2021094259A1 (en) 2019-11-11 2020-11-09 Npy2 receptor agonists

Publications (1)

Publication Number Publication Date
AU2020384729A1 true AU2020384729A1 (en) 2022-04-14

Family

ID=68531488

Family Applications (1)

Application Number Title Priority Date Filing Date
AU2020384729A Pending AU2020384729A1 (en) 2019-11-11 2020-11-09 NPY2 receptor agonists

Country Status (20)

Country Link
US (3) US20210139548A1 (https=)
EP (1) EP4058047A1 (https=)
JP (2) JP7821393B2 (https=)
KR (1) KR20220100925A (https=)
CN (1) CN114641303A (https=)
AR (1) AR120440A1 (https=)
AU (1) AU2020384729A1 (https=)
CA (1) CA3156452A1 (https=)
CL (1) CL2022001227A1 (https=)
CO (1) CO2022006046A2 (https=)
CR (1) CR20220206A (https=)
DO (1) DOP2022000097A (https=)
EC (1) ECSP22037660A (https=)
IL (1) IL292601A (https=)
JO (1) JOP20220110A1 (https=)
MX (1) MX2022005661A (https=)
PE (1) PE20221168A1 (https=)
PH (1) PH12022551101A1 (https=)
TW (1) TWI864155B (https=)
WO (1) WO2021094259A1 (https=)

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JP2025526148A (ja) * 2022-08-18 2025-08-07 ベーリンガー インゲルハイム インターナショナル ゲゼルシャフト ミット ベシュレンクテル ハフツング 長時間作用型ｇｌｐ－１／グルカゴン受容体アゴニスト及びｎｐｙ２受容体アゴニストを含む組合せ治療
CN120865433A (zh) * 2022-12-21 2025-10-31 勃林格殷格翰国际有限公司 Glp1/gip/npy2受体的三重激动剂
EP4670741A1 (en) 2023-04-28 2025-12-31 Pinotbio, Inc. ANTIBODY-DRUG CONJUGATE IN WHICH ONE OR MORE DRUG-BINDER CONJUGATES ARE LINKED TO AN ANTIBODY AND ITS PREPARATION METHOD

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Publication number Publication date
US20210139548A1 (en) 2021-05-13
JP2023500895A (ja) 2023-01-11
TWI864155B (zh) 2024-12-01
AR120440A1 (es) 2022-02-16
JOP20220110A1 (ar) 2023-01-30
CO2022006046A2 (es) 2022-05-20
TW202134263A (zh) 2021-09-16
CR20220206A (es) 2022-06-16
JP7821393B2 (ja) 2026-02-27
ECSP22037660A (es) 2022-06-30
JP2026026081A (ja) 2026-02-16
PE20221168A1 (es) 2022-07-25
KR20220100925A (ko) 2022-07-18
PH12022551101A1 (en) 2023-11-13
US12559529B2 (en) 2026-02-24
EP4058047A1 (en) 2022-09-21
CL2022001227A1 (es) 2023-02-03
US20230340039A1 (en) 2023-10-26
US12054525B2 (en) 2024-08-06
US20250002544A1 (en) 2025-01-02
IL292601A (en) 2022-07-01
MX2022005661A (es) 2022-09-07
DOP2022000097A (es) 2022-06-15
WO2021094259A1 (en) 2021-05-20
CA3156452A1 (en) 2021-05-20
CN114641303A (zh) 2022-06-17

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