JP2022552445A5 - - Google Patents

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Publication number
JP2022552445A5
JP2022552445A5 JP2022546591A JP2022546591A JP2022552445A5 JP 2022552445 A5 JP2022552445 A5 JP 2022552445A5 JP 2022546591 A JP2022546591 A JP 2022546591A JP 2022546591 A JP2022546591 A JP 2022546591A JP 2022552445 A5 JP2022552445 A5 JP 2022552445A5
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JP
Japan
Prior art keywords
optionally substituted
alkyl
group
pharmaceutically acceptable
occurrence
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Application number
JP2022546591A
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English (en)
Japanese (ja)
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JP2022552445A (ja
JP7697954B2 (ja
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Priority claimed from PCT/US2020/054373 external-priority patent/WO2021071821A1/en
Publication of JP2022552445A publication Critical patent/JP2022552445A/ja
Publication of JP2022552445A5 publication Critical patent/JP2022552445A5/ja
Application granted granted Critical
Publication of JP7697954B2 publication Critical patent/JP7697954B2/ja
Active legal-status Critical Current
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JP2022546591A 2019-10-07 2020-10-06 Ｋｖ１．３カリウムシェーカーチャネル遮断薬としてのアリールメチレン芳香族化合物 Active JP7697954B2 (ja)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US201962911653P 2019-10-07 2019-10-07
US62/911,653 2019-10-07
PCT/US2020/054373 WO2021071821A1 (en) 2019-10-07 2020-10-06 Arylmethylene aromatic compounds as kv1.3 potassium shaker channel blockers

Publications (3)

Publication Number Publication Date
JP2022552445A JP2022552445A (ja) 2022-12-15
JP2022552445A5 true JP2022552445A5 (https=) 2024-09-06
JP7697954B2 JP7697954B2 (ja) 2025-06-24

Family

ID=75438313

Family Applications (1)

Application Number Title Priority Date Filing Date
JP2022546591A Active JP7697954B2 (ja) 2019-10-07 2020-10-06 Ｋｖ１．３カリウムシェーカーチャネル遮断薬としてのアリールメチレン芳香族化合物

Country Status (11)

Country Link
US (1) US20230131535A1 (https=)
EP (1) EP4041230A4 (https=)
JP (1) JP7697954B2 (https=)
KR (1) KR20220079879A (https=)
CN (1) CN114727992A (https=)
AU (1) AU2020363366A1 (https=)
BR (1) BR112022006242A2 (https=)
CA (1) CA3157026A1 (https=)
IL (1) IL291733A (https=)
MX (1) MX2022004168A (https=)
WO (1) WO2021071821A1 (https=)

Families Citing this family (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
MX2023003841A (es) 2020-10-06 2023-06-23 De Shaw Res Llc Compuestos lactámicos como bloqueadores del canal agitador de potasio kv1.3.
US20240116962A1 (en) * 2020-12-31 2024-04-11 Tsinghua University Pyridine-2-amine derivative and pharmaceutical composition and use thereof
AU2022239717A1 (en) 2021-03-15 2023-11-02 Maze Therapeutics, Inc. Inhibitors of glycogen synthase 1 (gys1) and methods of use thereof
CN115703734B (zh) * 2021-08-05 2024-08-09 重庆文理学院 二芳基甲基吡啶类化合物及其制备方法和应用
TW202345806A (zh) 2022-03-31 2023-12-01 美商艾伯維有限公司 噻唑并〔５，４－ｂ〕吡啶ｍａｌｔ－１抑制劑
CN120202194A (zh) 2022-11-16 2025-06-24 巴斯夫欧洲公司 作为杀真菌剂的取代的四氢苯并二氮杂䓬
WO2024104815A1 (en) 2022-11-16 2024-05-23 Basf Se Substituted benzodiazepines as fungicides
KR20250156732A (ko) 2023-03-17 2025-11-03 바스프 에스이 식물병원성 진균을 퇴치하기 위한 치환된 피리딜/피라지딜 디히드로벤조티아제핀 화합물
TW202521512A (zh) 2023-07-31 2025-06-01 美商美國禮來大藥廠 Kv1.3鉀shaker通道阻斷劑之固體形式及其使用方法
WO2026057374A1 (en) 2024-09-11 2026-03-19 Basf Se Fungicidal mixture comprising substituted pyridyl/pyrazidyl dihydrobenzothiazepine compounds

Family Cites Families (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CH540009A (de) * 1970-07-23 1973-09-28 Ciba Geigy Ag Verwendung von Monohydroxyphenylcarbinolen zum antimikrobiellen Ausrüsten bzw. zum Schützen von textilen Materialien gegen schädliche Mikroorganismen
JPH07309837A (ja) * 1993-04-28 1995-11-28 Takeda Chem Ind Ltd ピリジン誘導体、その製造法および剤
JPH09278757A (ja) * 1996-04-15 1997-10-28 Takeda Chem Ind Ltd ヒドラゾン誘導体および剤
TW467902B (en) 1996-07-31 2001-12-11 Bristol Myers Squibb Co Diphenyl heterocycles as potassium channel modulators
JP2002501912A (ja) 1998-01-29 2002-01-22 ブリストル−マイヤーズ スクイブ カンパニー ジアリール１、３、４−オキサジアゾロンのベンゾエート誘導体
EP1838690A2 (en) * 2004-12-21 2007-10-03 Devgen N.V. Compounds with kv4 ion channel activity
CN101888989A (zh) * 2007-10-04 2010-11-17 生态学有限公司 新型芳基钾通道阻断剂及其应用
GB0815784D0 (en) 2008-08-29 2008-10-08 Xention Ltd Novel potassium channel blockers
GB0909672D0 (en) 2009-06-04 2009-07-22 Xention Discovery Ltd Compounds
RU2595894C2 (ru) * 2010-08-27 2016-08-27 Грюненталь Гмбх Замещенные 2-окси-хинолин-3-карбоксамиды в качестве модуляторов kcnq2/3
AU2014244257B2 (en) * 2013-03-13 2017-12-14 Kristina M. PANNONE Triazine compounds and compositions thereof and methods for treating malaria and chemoprophylaxis
HUE053705T2 (hu) * 2015-08-27 2021-07-28 Pfizer Biciklusos kondenzált heteroaril- vagy aril- vegyületek IRAK4 modulátorokként
EP3490542A4 (en) * 2016-07-26 2020-07-08 Flagship Pioneering Innovations V, Inc. NEUROMODULATION COMPOSITIONS AND RELATED THERAPEUTIC METHODS FOR THE TREATMENT OF CANCER BY MODULATION OF AN ANTI-CANCER RESPONSE

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