JP2022550641A5 - - Google Patents
Info
- Publication number
- JP2022550641A5 JP2022550641A5 JP2022546588A JP2022546588A JP2022550641A5 JP 2022550641 A5 JP2022550641 A5 JP 2022550641A5 JP 2022546588 A JP2022546588 A JP 2022546588A JP 2022546588 A JP2022546588 A JP 2022546588A JP 2022550641 A5 JP2022550641 A5 JP 2022550641A5
- Authority
- JP
- Japan
- Prior art keywords
- alkyl
- pharmaceutically acceptable
- acceptable salt
- compound according
- cycloalkyl
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201962911642P | 2019-10-07 | 2019-10-07 | |
| US62/911,642 | 2019-10-07 | ||
| PCT/US2020/054348 WO2021071803A1 (en) | 2019-10-07 | 2020-10-06 | Aryl heterobicyclic compounds as kv1.3 potassium shaker channel blockers |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2022550641A JP2022550641A (ja) | 2022-12-02 |
| JP2022550641A5 true JP2022550641A5 (https=) | 2024-05-23 |
| JP7780439B2 JP7780439B2 (ja) | 2025-12-04 |
Family
ID=75436850
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2022546588A Active JP7780439B2 (ja) | 2019-10-07 | 2020-10-06 | Ｋｖ１．３カリウムシェーカーチャネル遮断薬としてのアリール複素二環式化合物 |
Country Status (11)
| Country | Link |
|---|---|
| US (1) | US20230040182A1 (https=) |
| EP (1) | EP4041408A4 (https=) |
| JP (1) | JP7780439B2 (https=) |
| KR (1) | KR20220079575A (https=) |
| CN (1) | CN114728177B (https=) |
| AU (1) | AU2020363354A1 (https=) |
| BR (1) | BR112022006250A2 (https=) |
| CA (1) | CA3156981C (https=) |
| IL (1) | IL291867A (https=) |
| MX (1) | MX2022004144A (https=) |
| WO (1) | WO2021071803A1 (https=) |
Families Citing this family (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| MX2023003841A (es) | 2020-10-06 | 2023-06-23 | De Shaw Res Llc | Compuestos lactámicos como bloqueadores del canal agitador de potasio kv1.3. |
| CN114437070A (zh) * | 2022-01-19 | 2022-05-06 | 广西-东盟食品检验检测中心 | 一种他达拉非新型衍生物的制备方法 |
| WO2024088343A1 (zh) * | 2022-10-28 | 2024-05-02 | 上海深势唯思科技有限责任公司 | 一种芳基杂环类Kv1.3抑制剂及其制备方法和用途 |
| TW202521512A (zh) | 2023-07-31 | 2025-06-01 | 美商美國禮來大藥廠 | Kv1.3鉀shaker通道阻斷劑之固體形式及其使用方法 |
| WO2026021011A1 (zh) * | 2024-07-26 | 2026-01-29 | 浙江海正药业股份有限公司 | 芳基三环类衍生物及其制备方法和用途 |
Family Cites Families (11)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2001007052A1 (en) * | 1999-07-21 | 2001-02-01 | Boehringer Ingelheim Pharmaceuticals, Inc. | Small molecules useful in the treatment of inflammatory disease |
| US6348486B1 (en) * | 2000-10-17 | 2002-02-19 | American Home Products Corporation | Methods for modulating bladder function |
| US6939968B2 (en) * | 2002-12-23 | 2005-09-06 | Bristol-Myers Squibb Company | Atropisomers of 3-substituted-4-arylquinolin-2-one derivatives |
| WO2005030729A1 (en) * | 2003-09-23 | 2005-04-07 | Merck & Co., Inc. | Isoquinoline potassium channel inhibitors |
| CN100530013C (zh) * | 2005-03-04 | 2009-08-19 | 松下电器产业株式会社 | 电子设备控制装置及其控制方法 |
| US7538110B2 (en) * | 2005-10-27 | 2009-05-26 | Adolor Corporation | Opioid antagonists |
| US8124636B2 (en) * | 2008-04-30 | 2012-02-28 | Hoffmann-La Roche Inc. | Imidazolidinone derivatives as 11B-HSD1 inhibitors |
| TW201026708A (en) * | 2008-12-12 | 2010-07-16 | Solvay Pharm Bv | Spiro azepane-oxazolidinones as Kv1.3 potassium channel blockers |
| WO2011073273A1 (en) * | 2009-12-16 | 2011-06-23 | Evotec Ag | Benzoxazine aryl sulfonamide derivatives as kv1.3 modulators |
| US20120065210A1 (en) * | 2010-09-15 | 2012-03-15 | Xin-Jie Chu | Substituted hexahydropyrrolo[1,2-c]imidazolones |
| TWI698438B (zh) * | 2015-03-13 | 2020-07-11 | 德商４Ｓｃ製藥公司 | Ｋv１.３抑制劑及其醫學應用 |
-
2020
- 2020-10-06 JP JP2022546588A patent/JP7780439B2/ja active Active
- 2020-10-06 MX MX2022004144A patent/MX2022004144A/es unknown
- 2020-10-06 US US17/766,837 patent/US20230040182A1/en active Pending
- 2020-10-06 EP EP20874328.6A patent/EP4041408A4/en active Pending
- 2020-10-06 IL IL291867A patent/IL291867A/en unknown
- 2020-10-06 BR BR112022006250A patent/BR112022006250A2/pt not_active IP Right Cessation
- 2020-10-06 AU AU2020363354A patent/AU2020363354A1/en not_active Abandoned
- 2020-10-06 KR KR1020227013493A patent/KR20220079575A/ko not_active Withdrawn
- 2020-10-06 CN CN202080084476.1A patent/CN114728177B/zh active Active
- 2020-10-06 CA CA3156981A patent/CA3156981C/en active Active
- 2020-10-06 WO PCT/US2020/054348 patent/WO2021071803A1/en not_active Ceased
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