JP2024510274A5 - - Google Patents
Info
- Publication number
- JP2024510274A5 JP2024510274A5 JP2023557092A JP2023557092A JP2024510274A5 JP 2024510274 A5 JP2024510274 A5 JP 2024510274A5 JP 2023557092 A JP2023557092 A JP 2023557092A JP 2023557092 A JP2023557092 A JP 2023557092A JP 2024510274 A5 JP2024510274 A5 JP 2024510274A5
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- JP
- Japan
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Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN2021081177 | 2021-03-16 | ||
| CNPCT/CN2021/081177 | 2021-03-16 | ||
| PCT/CN2021/106028 WO2022193499A1 (en) | 2021-03-16 | 2021-07-13 | Amino heteroaryl compounds and compositions |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2024510274A JP2024510274A (ja) | 2024-03-06 |
| JPWO2022193499A5 JPWO2022193499A5 (https=) | 2024-07-23 |
| JP2024510274A5 true JP2024510274A5 (https=) | 2024-07-23 |
Family
ID=83321944
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2023557092A Pending JP2024510274A (ja) | 2021-03-16 | 2021-07-13 | アミノヘテロアリール化合物および組成物 |
Country Status (6)
| Country | Link |
|---|---|
| US (1) | US20240246944A1 (https=) |
| EP (1) | EP4308556A4 (https=) |
| JP (1) | JP2024510274A (https=) |
| CN (1) | CN117083268B (https=) |
| CA (1) | CA3213816A1 (https=) |
| WO (1) | WO2022193499A1 (https=) |
Families Citing this family (10)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2022135430A1 (en) | 2020-12-22 | 2022-06-30 | InventisBio Co., Ltd. | Heteroaryl compounds, preparation methods and uses thereof |
| TW202233600A (zh) * | 2021-02-06 | 2022-09-01 | 大陸商正大天晴藥業集團股份有限公司 | 含聯環的ｔｙｋ２抑制劑化合物、藥物組合物及其用途 |
| JP2024539280A (ja) | 2021-10-25 | 2024-10-28 | カイメラ セラピューティクス， インコーポレイテッド | Ｔｙｋ２分解剤およびそれらの使用 |
| WO2024044486A1 (en) * | 2022-08-22 | 2024-02-29 | Ajax Therapeutics, Inc. | Jak2 inhibitor compounds |
| US20260098017A1 (en) * | 2022-12-24 | 2026-04-09 | Tianjin Pharmaceutical Biotechnology Co., Ltd. | Novel aromatic ring derivative containing amide substitution and use thereof |
| WO2024174229A1 (en) * | 2023-02-24 | 2024-08-29 | Anrui Biomedical Technology (Guangzhou) Co., Ltd. | Covalent binding compounds and compositions |
| CN116162093B (zh) * | 2023-04-25 | 2023-06-23 | 中南大学湘雅医院 | 一种tyk2抑制剂化合物及其用途 |
| CN117624126B (zh) * | 2023-12-05 | 2026-01-30 | 中国药科大学 | 选择性酪氨酸激酶2(tyk2)抑制剂化合物、合成方法及用途 |
| WO2025186427A1 (en) | 2024-03-08 | 2025-09-12 | Curia Spain, S.A.U. | Process for the preparation of deucravacitinib and intermediates thereof and method for purifying deucravacitinib |
| WO2025255092A1 (en) * | 2024-06-03 | 2025-12-11 | Artax Biopharma Inc. | Combination of a chromene derivative tcr inhibitor and a tyk2 inhibitor |
Family Cites Families (23)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| MY194668A (en) | 2012-11-08 | 2022-12-12 | Bristol Myers Squibb Co | Amide-substituted heterocyclic compounds useful as modulators of il-12, il-23 and/or ifn() responses |
| AR094537A1 (es) * | 2013-11-07 | 2015-08-12 | Bristol Myers Squibb Co | COMPUESTOS DE PIRIDILO SUSTITUIDOS CON ALQUILAMIDA ÚTILES COMO MODULADORES DE LAS RESPUESTAS DE IL-12, IL-23 Y/O IFNa |
| EP3080131B1 (en) | 2013-12-10 | 2018-10-10 | Bristol-Myers Squibb Company | Imidazopyridazine compounds useful as modulators of il-12, il-23 and/or ifn alpha responses |
| US10479793B2 (en) | 2015-11-18 | 2019-11-19 | Bristol-Myers Squibb Company | Imidazopyridazine compounds useful as modulators of IL-12, IL-23 and/or IFN alpha responses |
| ES2902995T3 (es) | 2016-10-07 | 2022-03-30 | Bristol Myers Squibb Co | Compuestos de imidazopiridazina útiles como moduladores de respuestas a IL-12, IL-23 y/o IFN alfa |
| EP3848370B1 (en) | 2016-10-14 | 2025-05-07 | Takeda Pharmaceutical Company Limited | Tyk2 inhibitors and uses thereof |
| EP3528816A4 (en) | 2016-10-21 | 2020-04-08 | Nimbus Lakshmi, Inc. | TYK2 INHIBITORS AND USES THEREOF |
| EP3541817B1 (en) | 2016-11-17 | 2020-12-23 | Bristol-Myers Squibb Company | Imidazopyridazine modulators of il-12, il-23 and/or ifn-alpha |
| CN110267964B (zh) | 2016-12-13 | 2022-05-03 | 百时美施贵宝公司 | 作为IL-12、IL-23及/或IFNα响应调节剂的经取代的杂芳基氧化膦化合物 |
| KR102717819B1 (ko) | 2017-07-28 | 2024-10-14 | 다케다 야쿠힌 고교 가부시키가이샤 | Tyk2 억제제 및 이의 용도 |
| MX2020005210A (es) | 2017-11-21 | 2020-08-20 | Bristol Myers Squibb Co | Compuestos de heteroarilo sustituidos con alquilamida de piridinsulfona. |
| EP3768667B1 (en) | 2018-03-22 | 2023-04-12 | Bristol-Myers Squibb Company | Heterocyclic compounds comprising pyridine useful as modulators of il-12, il-23 and/or ifn alpha responses |
| JP7179161B2 (ja) | 2018-09-10 | 2022-11-28 | イーライ リリー アンド カンパニー | 乾癬および全身性エリテマトーデスの処置に有用なピラゾロ［１，５－ａ］ピリミジン－３－カルボキサミド誘導体 |
| JP7619951B2 (ja) | 2018-10-15 | 2025-01-22 | 武田薬品工業株式会社 | Ｔｙｋ２阻害剤およびその使用 |
| AU2019364336B2 (en) | 2018-10-22 | 2023-11-16 | Alumis Inc. | TYK2 inhibitors and uses thereof |
| CA3118094A1 (en) * | 2018-10-30 | 2020-05-07 | Bristol-Myers Squibb Company | Amide-substituted heterocyclic compounds for the treatment of conditions related to the modulation of il-12, il-23 and/or ifn-alpha |
| JP7530360B2 (ja) | 2018-11-30 | 2024-08-07 | 武田薬品工業株式会社 | Ｔｙｋ２阻害剤およびその使用 |
| TWI800696B (zh) | 2018-12-10 | 2023-05-01 | 美商美國禮來大藥廠 | 7-(甲基胺基)吡唑并[1,5-a]嘧啶-3-甲醯胺衍生物 |
| CN111757878B (zh) | 2019-01-28 | 2023-07-28 | 江苏豪森药业集团有限公司 | 一种哒嗪类衍生物抑制剂、其制备方法和应用 |
| CN111484480B (zh) * | 2019-01-29 | 2023-08-11 | 上海翰森生物医药科技有限公司 | 一种多环类衍生物抑制剂、其制备方法和应用 |
| WO2020159904A1 (en) * | 2019-01-30 | 2020-08-06 | Bristol-Myers Squibb Company | Amide-disubstituted pyridine or pyridazine compounds |
| CN111909140A (zh) | 2019-04-12 | 2020-11-10 | 明慧医药（杭州）有限公司 | 作为tyk2抑制剂的杂环化合物及合成和使用方法 |
| JP2023523438A (ja) * | 2020-04-28 | 2023-06-05 | ブリストル－マイヤーズ スクイブ カンパニー | 置換ヘテロ環式化合物 |
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2021
- 2021-07-13 EP EP21931081.0A patent/EP4308556A4/en active Pending
- 2021-07-13 CA CA3213816A patent/CA3213816A1/en active Pending
- 2021-07-13 CN CN202180095847.0A patent/CN117083268B/zh active Active
- 2021-07-13 JP JP2023557092A patent/JP2024510274A/ja active Pending
- 2021-07-13 US US18/550,898 patent/US20240246944A1/en active Pending
- 2021-07-13 WO PCT/CN2021/106028 patent/WO2022193499A1/en not_active Ceased