JP2022551197A5 - - Google Patents
Info
- Publication number
- JP2022551197A5 JP2022551197A5 JP2022546589A JP2022546589A JP2022551197A5 JP 2022551197 A5 JP2022551197 A5 JP 2022551197A5 JP 2022546589 A JP2022546589 A JP 2022546589A JP 2022546589 A JP2022546589 A JP 2022546589A JP 2022551197 A5 JP2022551197 A5 JP 2022551197A5
- Authority
- JP
- Japan
- Prior art keywords
- optionally substituted
- alkyl
- pharmaceutically acceptable
- cycloalkyl
- acceptable salt
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP2024187488A JP2025020196A (ja) | 2019-10-07 | 2024-10-24 | Ｋｖ１．３カリウムシェーカーチャネル遮断薬としてのアリールメチレン複素環式化合物 |
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201962911655P | 2019-10-07 | 2019-10-07 | |
| US62/911,655 | 2019-10-07 | ||
| PCT/US2020/054352 WO2021071806A1 (en) | 2019-10-07 | 2020-10-06 | Arylmethylene heterocyclic compounds as kv1.3 potassium shaker channel blockers |
Related Child Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2024187488A Division JP2025020196A (ja) | 2019-10-07 | 2024-10-24 | Ｋｖ１．３カリウムシェーカーチャネル遮断薬としてのアリールメチレン複素環式化合物 |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2022551197A JP2022551197A (ja) | 2022-12-07 |
| JP2022551197A5 true JP2022551197A5 (https=) | 2024-05-31 |
| JP7578704B2 JP7578704B2 (ja) | 2024-11-06 |
Family
ID=75436854
Family Applications (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2022546589A Active JP7578704B2 (ja) | 2019-10-07 | 2020-10-06 | Ｋｖ１．３カリウムシェーカーチャネル遮断薬としてのアリールメチレン複素環式化合物 |
| JP2024187488A Pending JP2025020196A (ja) | 2019-10-07 | 2024-10-24 | Ｋｖ１．３カリウムシェーカーチャネル遮断薬としてのアリールメチレン複素環式化合物 |
Family Applications After (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2024187488A Pending JP2025020196A (ja) | 2019-10-07 | 2024-10-24 | Ｋｖ１．３カリウムシェーカーチャネル遮断薬としてのアリールメチレン複素環式化合物 |
Country Status (19)
| Country | Link |
|---|---|
| US (1) | US20230023559A1 (https=) |
| EP (1) | EP4041229A4 (https=) |
| JP (2) | JP7578704B2 (https=) |
| KR (1) | KR20220079880A (https=) |
| CN (1) | CN114727991B (https=) |
| AU (1) | AU2020363356A1 (https=) |
| BR (1) | BR112022006507A2 (https=) |
| CA (1) | CA3156982A1 (https=) |
| CL (1) | CL2022000802A1 (https=) |
| CO (1) | CO2022004305A2 (https=) |
| CR (1) | CR20220148A (https=) |
| DO (1) | DOP2022000068A (https=) |
| EC (1) | ECSP22027871A (https=) |
| IL (1) | IL291734A (https=) |
| JO (1) | JOP20220085A1 (https=) |
| MX (1) | MX2022004128A (https=) |
| PE (1) | PE20230177A1 (https=) |
| PH (1) | PH12022550832A1 (https=) |
| WO (1) | WO2021071806A1 (https=) |
Families Citing this family (10)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| IL326597A (en) | 2019-10-07 | 2026-04-01 | Contineum Therapeutics Inc | Muscarinic M1 acetylcholine receptor antagonists |
| US11752149B2 (en) | 2019-12-02 | 2023-09-12 | Pipeline Therapeutics, Inc. | Muscarinic acetylcholine M1 receptor antagonists |
| MX2023003841A (es) | 2020-10-06 | 2023-06-23 | De Shaw Res Llc | Compuestos lactámicos como bloqueadores del canal agitador de potasio kv1.3. |
| EP4351569A4 (en) | 2021-05-28 | 2025-04-16 | D.E. Shaw Research, LLC | Spiroindolinone compounds as kv1.3 potassium shaker channel blockers |
| WO2023122325A2 (en) * | 2021-12-23 | 2023-06-29 | Regents Of The University Of Michigan | Meta anilide compounds and methods for use of the same to treat diseases and disorders |
| WO2024088343A1 (zh) * | 2022-10-28 | 2024-05-02 | 上海深势唯思科技有限责任公司 | 一种芳基杂环类Kv1.3抑制剂及其制备方法和用途 |
| WO2025017105A1 (en) * | 2023-07-18 | 2025-01-23 | Muna Therapeutics Aps | Kv1.3 potassium channel antagonists |
| AR133292A1 (es) * | 2023-07-18 | 2025-09-17 | Muna Therapeutics Aps | Antagonistas del canal de potasio kv1.3 |
| TW202521512A (zh) | 2023-07-31 | 2025-06-01 | 美商美國禮來大藥廠 | Kv1.3鉀shaker通道阻斷劑之固體形式及其使用方法 |
| CN117105996B (zh) * | 2023-10-24 | 2024-02-06 | 北京瑞博奥医药科技有限公司 | 一种脱氧核糖衍生物的制备的方法 |
Family Cites Families (19)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US3854480A (en) | 1969-04-01 | 1974-12-17 | Alza Corp | Drug-delivery system |
| US4675189A (en) | 1980-11-18 | 1987-06-23 | Syntex (U.S.A.) Inc. | Microencapsulation of water soluble active polypeptides |
| US4452775A (en) | 1982-12-03 | 1984-06-05 | Syntex (U.S.A.) Inc. | Cholesterol matrix delivery system for sustained release of macromolecules |
| US5075109A (en) | 1986-10-24 | 1991-12-24 | Southern Research Institute | Method of potentiating an immune response |
| US5133974A (en) | 1989-05-05 | 1992-07-28 | Kv Pharmaceutical Company | Extended release pharmaceutical formulations |
| US5407686A (en) | 1991-11-27 | 1995-04-18 | Sidmak Laboratories, Inc. | Sustained release composition for oral administration of active ingredient |
| US5736152A (en) | 1995-10-27 | 1998-04-07 | Atrix Laboratories, Inc. | Non-polymeric sustained release delivery system |
| WO2006029182A2 (en) | 2004-09-07 | 2006-03-16 | The La Jolla Institute For Molecular Medicine | Use of mdl-100,907 for treatment of allergic and eosinophil mediated diseases |
| BRPI0516132A (pt) * | 2004-10-07 | 2007-12-04 | Vitae Pharmaceuticals Inc | compostos, composição destes, método de antagonização de uma ou mais proteases aspárticas e método para tratar ou melhorar um distúrbio mediado por protease aspártica |
| AR056317A1 (es) | 2005-04-20 | 2007-10-03 | Xenon Pharmaceuticals Inc | Compuestos de oxindol y composicion farmaceutica |
| US20090275581A1 (en) | 2006-04-05 | 2009-11-05 | Baldwin John J | Renin inhibitors |
| WO2011073277A1 (en) * | 2009-12-16 | 2011-06-23 | Evotec Ag | PIPERIDINE ARYL SULFONAMIDE DERIVATIVES AS Kv1.3 MODULATORS |
| WO2011103715A1 (en) | 2010-02-25 | 2011-09-01 | Merck Sharp & Dohme Corp. | Task channel antagonists |
| CN103781763B (zh) | 2011-05-16 | 2017-03-22 | 生态学有限公司 | 作为钾通道阻断剂的胺衍生物 |
| HUE053705T2 (hu) * | 2015-08-27 | 2021-07-28 | Pfizer | Biciklusos kondenzált heteroaril- vagy aril- vegyületek IRAK4 modulátorokként |
| CN109843882A (zh) * | 2016-06-16 | 2019-06-04 | 豪夫迈·罗氏有限公司 | 四氢-吡啶并[3,4-b]吲哚雌激素受体调节剂及其用途 |
| EP3478678A1 (en) * | 2016-06-30 | 2019-05-08 | Basilea Pharmaceutica International AG | Mitochondrial inhibitors for the treatment of proliferation disorders |
| EP3375778A1 (en) | 2017-03-14 | 2018-09-19 | Artax Biopharma Inc. | Aryl-piperidine derivatives |
| PE20211089A1 (es) * | 2018-08-13 | 2021-06-14 | Hoffmann La Roche | Nuevos compuestos heterociclicos como inhibidores de la monoacilglicerol lipasa |
-
2020
- 2020-10-06 BR BR112022006507A patent/BR112022006507A2/pt unknown
- 2020-10-06 CN CN202080084382.4A patent/CN114727991B/zh active Active
- 2020-10-06 CR CR20220148A patent/CR20220148A/es unknown
- 2020-10-06 US US17/766,885 patent/US20230023559A1/en active Pending
- 2020-10-06 CA CA3156982A patent/CA3156982A1/en active Pending
- 2020-10-06 KR KR1020227013507A patent/KR20220079880A/ko active Pending
- 2020-10-06 PE PE2022000534A patent/PE20230177A1/es unknown
- 2020-10-06 EP EP20874462.3A patent/EP4041229A4/en active Pending
- 2020-10-06 AU AU2020363356A patent/AU2020363356A1/en not_active Abandoned
- 2020-10-06 MX MX2022004128A patent/MX2022004128A/es unknown
- 2020-10-06 WO PCT/US2020/054352 patent/WO2021071806A1/en not_active Ceased
- 2020-10-06 JP JP2022546589A patent/JP7578704B2/ja active Active
- 2020-10-06 PH PH1/2022/550832A patent/PH12022550832A1/en unknown
-
2022
- 2022-03-27 IL IL291734A patent/IL291734A/en unknown
- 2022-03-30 CL CL2022000802A patent/CL2022000802A1/es unknown
- 2022-03-31 DO DO2022000068A patent/DOP2022000068A/es unknown
- 2022-04-05 CO CONC2022/0004305A patent/CO2022004305A2/es unknown
- 2022-04-06 JO JOP/2022/0085A patent/JOP20220085A1/ar unknown
- 2022-04-07 EC ECSENADI202227871A patent/ECSP22027871A/es unknown
-
2024
- 2024-10-24 JP JP2024187488A patent/JP2025020196A/ja active Pending
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| JP2022551197A5 (https=) | ||
| JP2022550640A5 (https=) | ||
| JP2022552445A5 (https=) | ||
| DE60003709T2 (de) | Substituierte azole | |
| JP2022550641A5 (https=) | ||
| JP2007524696A5 (https=) | ||
| JP2010519204A5 (https=) | ||
| JP7368365B2 (ja) | Ｐ３００／ｃｂｐ ｈａｔ阻害剤及びそれらの使用の方法 | |
| JP2009500347A5 (https=) | ||
| CA2475455A1 (en) | Process for preparing indolinone derivatives | |
| JP2022519239A5 (https=) | ||
| DK157545B (da) | Analogifremgangsmaade til fremstilling af 4-fenyl-1-hydroxyalkylimidazolderivater eller farmaceutisk acceptable syreadditionssalte deraf | |
| JPH04321677A (ja) | 新規の２−メトキシフェニルピペラジン誘導体 | |
| JP2024522718A (ja) | 神経変性疾患の治療のための、カルボン酸基を含むアゼチジニル化合物 | |
| WO2023107563A1 (en) | Carboxylic acid containing indanyl compounds for the treatment of neurodegenerative diseases | |
| JP2020506906A (ja) | Ｊａｋ酵素阻害剤及びその製造方法と用途 | |
| JP2024512931A5 (https=) | ||
| JP2008539183A (ja) | オキサゾールおよびチアゾール化合物ならびにｐｇｅ２介在障害の治療におけるそれらの使用 | |
| JP2022551198A5 (https=) | ||
| DE3615180C2 (de) | Disubstituierte 1,4-Piperazinylderivate, Verfahren zu deren Herstellung und diese Verbindungen enthaltende pharmazeutische Mittel | |
| CN115667272A (zh) | 一类jak激酶抑制剂及其制备和应用 | |
| JPH01265092A (ja) | ピリドン系抗菌剤 | |
| US3268529A (en) | 3-cyanoalkyl substituted 4-(3h)-quinazolinones | |
| CN120019042A (zh) | 用于治疗神经退行性疾病的化合物 | |
| JPH0133466B2 (https=) |