JP2024512931A5 - - Google Patents

Info

Publication number
JP2024512931A5
JP2024512931A5 JP2023556737A JP2023556737A JP2024512931A5 JP 2024512931 A5 JP2024512931 A5 JP 2024512931A5 JP 2023556737 A JP2023556737 A JP 2023556737A JP 2023556737 A JP2023556737 A JP 2023556737A JP 2024512931 A5 JP2024512931 A5 JP 2024512931A5
Authority
JP
Japan
Prior art keywords
compound
tautomer
pharmaceutically acceptable
acceptable salt
optionally substituted
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
JP2023556737A
Other languages
English (en)
Japanese (ja)
Other versions
JP2024512931A (ja
Filing date
Publication date
Application filed filed Critical
Priority claimed from PCT/CN2022/081544 external-priority patent/WO2022194259A1/en
Publication of JP2024512931A publication Critical patent/JP2024512931A/ja
Publication of JP2024512931A5 publication Critical patent/JP2024512931A5/ja
Pending legal-status Critical Current

Links

JP2023556737A 2021-03-18 2022-03-17 受容体相互作用タンパク質1阻害剤、その調製、及び使用 Pending JP2024512931A (ja)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
CN2021081514 2021-03-18
CNPCT/CN2021/081514 2021-03-18
PCT/CN2022/081544 WO2022194259A1 (en) 2021-03-18 2022-03-17 Receptor-interacting protein 1 inhibitors, preparations, and uses thereof

Publications (2)

Publication Number Publication Date
JP2024512931A JP2024512931A (ja) 2024-03-21
JP2024512931A5 true JP2024512931A5 (https=) 2025-03-25

Family

ID=83321909

Family Applications (1)

Application Number Title Priority Date Filing Date
JP2023556737A Pending JP2024512931A (ja) 2021-03-18 2022-03-17 受容体相互作用タンパク質1阻害剤、その調製、及び使用

Country Status (7)

Country Link
US (1) US20240217963A1 (https=)
EP (1) EP4308555A4 (https=)
JP (1) JP2024512931A (https=)
CN (1) CN117500795A (https=)
CA (1) CA3209628A1 (https=)
IL (1) IL305530A (https=)
WO (1) WO2022194259A1 (https=)

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2024233544A1 (en) 2023-05-10 2024-11-14 Genzyme Corporation Isoxazolidines as ripk1 inhibitors and use thereof
CN121487930A (zh) 2023-05-10 2026-02-06 建新公司 作为ripk1抑制剂的异噁唑烷及其用途
CN121079291A (zh) 2023-05-10 2025-12-05 建新公司 作为ripk1抑制剂的异噁唑烷及其使用
CN120607513A (zh) * 2024-03-08 2025-09-09 山东全重生物医药科技有限公司 Ripk1抑制剂、其制备方法及其在医药上的应用

Family Cites Families (14)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA2637620A1 (en) * 2006-02-16 2007-08-30 Boehringer Ingelheim International Gmbh Substituted pyridineamide compounds useful as soluble epoxide hydrolase inhibitors
TW200815426A (en) * 2006-06-28 2008-04-01 Astrazeneca Ab New pyridine analogues II 333
WO2008005368A2 (en) * 2006-06-30 2008-01-10 Abbott Laboratories Piperazines as p2x7 antagonists
ES2404580T3 (es) * 2007-10-11 2013-05-28 Glaxosmithkline Llc Novedosos inhibidores de la ehs y uso de los mismos
JP2011510996A (ja) * 2008-01-30 2011-04-07 グラクソスミスクライン・リミテッド・ライアビリティ・カンパニー 新規sEH阻害剤およびその使用
CA2813162C (en) * 2010-10-20 2015-06-16 Pfizer Inc. Pyridine-2- derivatives as smoothened receptor modulators
HUE039922T2 (hu) * 2012-12-11 2019-02-28 Takeda Pharmaceuticals Co Heterociklusos vegyületek
WO2016101885A1 (en) * 2014-12-24 2016-06-30 National Institute Of Biological Sciences, Beijing Necrosis inhibitors
EP3224245B1 (en) * 2014-12-24 2018-09-12 National Institute Of Biological Sciences, Beijing Necrosis inhibitors
TWI730959B (zh) * 2015-05-19 2021-06-21 英商葛蘭素史克智慧財產發展有限公司 作為激酶抑制劑之雜環醯胺
TW201831464A (zh) * 2016-11-18 2018-09-01 英商葛蘭素史克智慧財產發展有限公司 作為激酶抑制劑之雜環醯胺
SG11202105250TA (en) * 2018-11-20 2021-06-29 Sironax Ltd Cyclic Ureas
CN113272272B (zh) * 2018-11-20 2023-04-07 圣瑞诺有限公司 Rip1抑制剂
KR20200087922A (ko) * 2019-01-11 2020-07-22 보로노이바이오 주식회사 (3-페닐이속사졸리딘-2-일)(피페리딘-4-일)메타논 유도체 및 이를 유효성분으로 포함하는 키나아제 관련 질환 치료용 약학적 조성물

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