JP2025505644A5 - - Google Patents
Info
- Publication number
- JP2025505644A5 JP2025505644A5 JP2024546422A JP2024546422A JP2025505644A5 JP 2025505644 A5 JP2025505644 A5 JP 2025505644A5 JP 2024546422 A JP2024546422 A JP 2024546422A JP 2024546422 A JP2024546422 A JP 2024546422A JP 2025505644 A5 JP2025505644 A5 JP 2025505644A5
- Authority
- JP
- Japan
- Prior art keywords
- groups
- optionally substituted
- alkyl
- independently selected
- halogen
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US202263307876P | 2022-02-08 | 2022-02-08 | |
| US63/307,876 | 2022-02-08 | ||
| PCT/US2023/012578 WO2023154309A1 (en) | 2022-02-08 | 2023-02-08 | 4',5'-dihydrospiro[piperidine-4,7'-thieno[2,3-c]pyran] derivatives as inhibitors of apol1 and methods of using same |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JP2025505644A JP2025505644A (ja) | 2025-02-28 |
| JP2025505644A5 true JP2025505644A5 (https=) | 2026-02-04 |
Family
ID=85685675
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2024546422A Pending JP2025505644A (ja) | 2022-02-08 | 2023-02-08 | Ａｐｏｌ１の阻害剤としての４’，５’－ジヒドロスピロ［ピペリジン－４，７’－チエノ［２，３－ｃ］ピラン］誘導体、及びそれを使用する方法 |
Country Status (7)
| Country | Link |
|---|---|
| US (1) | US20250136612A1 (https=) |
| EP (1) | EP4476228A1 (https=) |
| JP (1) | JP2025505644A (https=) |
| CN (1) | CN119013281A (https=) |
| AU (1) | AU2023218939A1 (https=) |
| CA (1) | CA3251124A1 (https=) |
| WO (1) | WO2023154309A1 (https=) |
Families Citing this family (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US11618746B2 (en) | 2018-12-17 | 2023-04-04 | Vertex Pharmaceuticals Incorporated | Inhibitors of APOL1 and methods of using same |
| WO2021154997A1 (en) | 2020-01-29 | 2021-08-05 | Vertex Pharmaceuticals Incorporated | Inhibitors of apol1 and methods of using same |
| CN115867543A (zh) | 2020-06-12 | 2023-03-28 | 弗特克斯药品有限公司 | Apol1抑制剂的固体形式及其使用方法 |
| CA3185604A1 (en) | 2020-06-12 | 2021-12-16 | Vertex Pharmaceuticals Incorporated | Inhibitors of apol1 and use of the same |
| CN116547287B (zh) | 2020-08-26 | 2025-09-26 | 弗特克斯药品有限公司 | Apol1的抑制剂及其使用方法 |
| US12612379B2 (en) | 2021-11-30 | 2026-04-28 | Vertex Pharmaceuticals Incorporated | Inhibitors of APOL1 and methods of using same |
| MX2024008868A (es) | 2022-01-18 | 2024-09-23 | Maze Therapeutics Inc | Inhibidores de la apolipoproteína l1 (apol1) y métodos de uso. |
Family Cites Families (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP2020414A1 (en) * | 2007-06-20 | 2009-02-04 | Laboratorios del Dr. Esteve S.A. | spiro[piperidine-4,4'-thieno[3,2-c]pyran] derivatives and related compounds as inhibitors of the sigma receptor for the treatment of psychosis |
| WO2021220178A1 (en) * | 2020-04-29 | 2021-11-04 | Cominnex Zrt. | Iap antagonists and their therapeutic applications |
| CN115867532A (zh) * | 2020-06-12 | 2023-03-28 | 弗特克斯药品有限公司 | Apol1的抑制剂及其用途 |
-
2023
- 2023-02-08 EP EP23711582.9A patent/EP4476228A1/en active Pending
- 2023-02-08 JP JP2024546422A patent/JP2025505644A/ja active Pending
- 2023-02-08 US US18/836,407 patent/US20250136612A1/en active Pending
- 2023-02-08 WO PCT/US2023/012578 patent/WO2023154309A1/en not_active Ceased
- 2023-02-08 CA CA3251124A patent/CA3251124A1/en active Pending
- 2023-02-08 AU AU2023218939A patent/AU2023218939A1/en active Pending
- 2023-02-08 CN CN202380032015.3A patent/CN119013281A/zh active Pending
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