JP2025505647A5 - - Google Patents
Info
- Publication number
- JP2025505647A5 JP2025505647A5 JP2024546426A JP2024546426A JP2025505647A5 JP 2025505647 A5 JP2025505647 A5 JP 2025505647A5 JP 2024546426 A JP2024546426 A JP 2024546426A JP 2024546426 A JP2024546426 A JP 2024546426A JP 2025505647 A5 JP2025505647 A5 JP 2025505647A5
- Authority
- JP
- Japan
- Prior art keywords
- groups
- optionally substituted
- alkyl
- compound
- independently selected
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US202263307875P | 2022-02-08 | 2022-02-08 | |
| US63/307,875 | 2022-02-08 | ||
| PCT/US2023/012618 WO2023154344A1 (en) | 2022-02-08 | 2023-02-08 | 2-methyl-4',5'-dihydrospiro[piperidine-4,7'-thieno[2,3-c]pyran] derivatives as inhibitors of apol1 and methods of using same |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JP2025505647A JP2025505647A (ja) | 2025-02-28 |
| JP2025505647A5 true JP2025505647A5 (https=) | 2026-02-04 |
Family
ID=85461631
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2024546426A Pending JP2025505647A (ja) | 2022-02-08 | 2023-02-08 | Ａｐｏｌ１阻害剤としての２－メチル－４’，５’－ジヒドロピロ［ピペリジン－４，７’－チエノ［２，３－ｃ］ピラン］誘導体、およびそれを使用する方法 |
Country Status (8)
| Country | Link |
|---|---|
| US (1) | US20250171459A1 (https=) |
| EP (1) | EP4476227A1 (https=) |
| JP (1) | JP2025505647A (https=) |
| CN (1) | CN119343353A (https=) |
| AU (1) | AU2023218994A1 (https=) |
| CA (1) | CA3251050A1 (https=) |
| CO (1) | CO2024012058A2 (https=) |
| WO (1) | WO2023154344A1 (https=) |
Families Citing this family (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US11618746B2 (en) | 2018-12-17 | 2023-04-04 | Vertex Pharmaceuticals Incorporated | Inhibitors of APOL1 and methods of using same |
| WO2021154997A1 (en) | 2020-01-29 | 2021-08-05 | Vertex Pharmaceuticals Incorporated | Inhibitors of apol1 and methods of using same |
| CN115867543A (zh) | 2020-06-12 | 2023-03-28 | 弗特克斯药品有限公司 | Apol1抑制剂的固体形式及其使用方法 |
| CA3185604A1 (en) | 2020-06-12 | 2021-12-16 | Vertex Pharmaceuticals Incorporated | Inhibitors of apol1 and use of the same |
| CN116547287B (zh) | 2020-08-26 | 2025-09-26 | 弗特克斯药品有限公司 | Apol1的抑制剂及其使用方法 |
| US12612379B2 (en) | 2021-11-30 | 2026-04-28 | Vertex Pharmaceuticals Incorporated | Inhibitors of APOL1 and methods of using same |
| MX2024008868A (es) * | 2022-01-18 | 2024-09-23 | Maze Therapeutics Inc | Inhibidores de la apolipoproteína l1 (apol1) y métodos de uso. |
Family Cites Families (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP2020414A1 (en) * | 2007-06-20 | 2009-02-04 | Laboratorios del Dr. Esteve S.A. | spiro[piperidine-4,4'-thieno[3,2-c]pyran] derivatives and related compounds as inhibitors of the sigma receptor for the treatment of psychosis |
| UA107943C2 (xx) * | 2009-11-16 | 2015-03-10 | Lilly Co Eli | Сполуки спіропіперидину як антагоністи рецептора orl-1 |
| AU2010319400B2 (en) * | 2009-11-16 | 2013-12-19 | Eli Lilly And Company | Spiropiperidine compounds as ORL-1 receptor antagonists |
| US11618746B2 (en) * | 2018-12-17 | 2023-04-04 | Vertex Pharmaceuticals Incorporated | Inhibitors of APOL1 and methods of using same |
| CN116547287B (zh) * | 2020-08-26 | 2025-09-26 | 弗特克斯药品有限公司 | Apol1的抑制剂及其使用方法 |
-
2023
- 2023-02-08 CA CA3251050A patent/CA3251050A1/en active Pending
- 2023-02-08 CN CN202380030500.7A patent/CN119343353A/zh active Pending
- 2023-02-08 AU AU2023218994A patent/AU2023218994A1/en active Pending
- 2023-02-08 JP JP2024546426A patent/JP2025505647A/ja active Pending
- 2023-02-08 US US18/836,539 patent/US20250171459A1/en active Pending
- 2023-02-08 EP EP23708611.1A patent/EP4476227A1/en active Pending
- 2023-02-08 WO PCT/US2023/012618 patent/WO2023154344A1/en not_active Ceased
-
2024
- 2024-09-04 CO CONC2024/0012058A patent/CO2024012058A2/es unknown
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| JP2025505647A5 (https=) | ||
| CA2774647C (en) | Substituted amide compound | |
| DK2038265T3 (en) | Inhibitors of human protein tyrosine phosphatase and methods of use | |
| DK2346841T3 (en) | 2-ARYL PROPIONIC ACIDS AND DERIVATIVES AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM | |
| JP5225076B2 (ja) | チアゾール環を含むカルボン酸誘導体の医薬用途 | |
| DE69232919T2 (de) | Verbindungen und Verfahren zur Inhibierung von HIV- und verwandten Viren | |
| JP6657413B2 (ja) | Ｐｐａｒアゴニスト、化合物、医薬組成物、及びその使用方法 | |
| JP2004502670A5 (https=) | ||
| JP2025505200A5 (https=) | ||
| AU2004259347A1 (en) | Method for modulating calcium ion-release-activated calcium ion channels | |
| RU2012116877A (ru) | Соединения 2-пиридона, применяемые в качестве ингибиторов нейтрофильной эластазы | |
| JPH11193281A (ja) | アデノシンａ３受容体拮抗剤およびチアゾール化合物 | |
| JP2025505645A5 (https=) | ||
| JP2024544060A5 (https=) | ||
| WO2012039460A1 (ja) | 置換アミド化合物 | |
| ZA200210283B (en) | Quinolinyl and benzothiazolyl ppar-gamma modulators | |
| JP2005506308A5 (https=) | ||
| JP2025505644A5 (https=) | ||
| RU2004129285A (ru) | Производные тиазола в качестве антагонистов рецептора npy | |
| JP2024509981A5 (https=) | ||
| JP4939226B2 (ja) | チアゾール環を含むカルボン酸誘導体およびその医薬用途 | |
| JP2006516626A5 (https=) | ||
| JP2007509052A5 (https=) | ||
| RU2435763C2 (ru) | Ингибиторы тирозинфосфатазы белка человека и способы применения | |
| JP5776695B2 (ja) | 置換アミド化合物 |