JP2024544060A5 - - Google Patents
Info
- Publication number
- JP2024544060A5 JP2024544060A5 JP2024532219A JP2024532219A JP2024544060A5 JP 2024544060 A5 JP2024544060 A5 JP 2024544060A5 JP 2024532219 A JP2024532219 A JP 2024532219A JP 2024532219 A JP2024532219 A JP 2024532219A JP 2024544060 A5 JP2024544060 A5 JP 2024544060A5
- Authority
- JP
- Japan
- Prior art keywords
- alkyl
- groups
- independently selected
- optionally substituted
- pharmaceutically acceptable
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US202163284195P | 2021-11-30 | 2021-11-30 | |
| US63/284,195 | 2021-11-30 | ||
| PCT/US2022/051274 WO2023101981A1 (en) | 2021-11-30 | 2022-11-29 | Spirocyclic inhibitors of apol1 and methods of using same |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JP2024544060A JP2024544060A (ja) | 2024-11-27 |
| JP2024544060A5 true JP2024544060A5 (https=) | 2025-10-30 |
Family
ID=84946826
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2024532219A Pending JP2024544060A (ja) | 2021-11-30 | 2022-11-29 | Ａｐｏｌ１のスピロ環式阻害剤およびこれを使用する方法 |
Country Status (7)
| Country | Link |
|---|---|
| US (1) | US20250084094A1 (https=) |
| EP (1) | EP4440697A1 (https=) |
| JP (1) | JP2024544060A (https=) |
| CN (1) | CN118632850A (https=) |
| AU (1) | AU2022401847A1 (https=) |
| CA (1) | CA3240523A1 (https=) |
| WO (1) | WO2023101981A1 (https=) |
Families Citing this family (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US11618746B2 (en) | 2018-12-17 | 2023-04-04 | Vertex Pharmaceuticals Incorporated | Inhibitors of APOL1 and methods of using same |
| WO2021154997A1 (en) | 2020-01-29 | 2021-08-05 | Vertex Pharmaceuticals Incorporated | Inhibitors of apol1 and methods of using same |
| CN115867543A (zh) | 2020-06-12 | 2023-03-28 | 弗特克斯药品有限公司 | Apol1抑制剂的固体形式及其使用方法 |
| CA3185604A1 (en) | 2020-06-12 | 2021-12-16 | Vertex Pharmaceuticals Incorporated | Inhibitors of apol1 and use of the same |
| CN116547287B (zh) | 2020-08-26 | 2025-09-26 | 弗特克斯药品有限公司 | Apol1的抑制剂及其使用方法 |
| US12612379B2 (en) | 2021-11-30 | 2026-04-28 | Vertex Pharmaceuticals Incorporated | Inhibitors of APOL1 and methods of using same |
| MX2024008868A (es) * | 2022-01-18 | 2024-09-23 | Maze Therapeutics Inc | Inhibidores de la apolipoproteína l1 (apol1) y métodos de uso. |
Family Cites Families (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US11618746B2 (en) * | 2018-12-17 | 2023-04-04 | Vertex Pharmaceuticals Incorporated | Inhibitors of APOL1 and methods of using same |
| WO2021154997A1 (en) * | 2020-01-29 | 2021-08-05 | Vertex Pharmaceuticals Incorporated | Inhibitors of apol1 and methods of using same |
| JP2023524563A (ja) * | 2020-05-07 | 2023-06-12 | ラムバム メド－テック リミテッド | Ａｐｏｌ１－関連疾患の治療に使用するための組成物 |
-
2022
- 2022-11-29 EP EP22843526.9A patent/EP4440697A1/en active Pending
- 2022-11-29 AU AU2022401847A patent/AU2022401847A1/en active Pending
- 2022-11-29 CN CN202280089820.5A patent/CN118632850A/zh active Pending
- 2022-11-29 JP JP2024532219A patent/JP2024544060A/ja active Pending
- 2022-11-29 WO PCT/US2022/051274 patent/WO2023101981A1/en not_active Ceased
- 2022-11-29 US US18/714,031 patent/US20250084094A1/en active Pending
- 2022-11-29 CA CA3240523A patent/CA3240523A1/en active Pending
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