|
DE3827253A1
(de)
|
1987-08-20 |
1989-03-02 |
Sandoz Ag |
Ester und amide von cyclischen carbonsaeuren und cyclischen alkoholen und aminen sowie verfahren zu deren herstellung und sie enthaltende therapeutische zusammensetzungen
|
|
JPH02262627A
(ja)
|
1988-12-08 |
1990-10-25 |
Japan Synthetic Rubber Co Ltd |
有機非線形光学素子
|
|
DE4014171A1
(de)
|
1990-05-03 |
1991-11-07 |
Basf Ag |
Cyanochinolinverbindungen
|
|
JPH0539272A
(ja)
|
1991-01-09 |
1993-02-19 |
Nissan Chem Ind Ltd |
ピリミジンジオン誘導体および除草剤
|
|
CA2075154A1
(en)
|
1991-08-06 |
1993-02-07 |
Neelakantan Balasubramanian |
Peptide aldehydes as antithrombotic agents
|
|
DE4126244A1
(de)
|
1991-08-08 |
1993-02-11 |
Bayer Ag |
Massefaerben von kunststoffen
|
|
GB9221383D0
(en)
|
1992-10-12 |
1992-11-25 |
Minnesota Mining & Mfg |
Photothermographic imaging materials and antifoggants therefor
|
|
US5374514A
(en)
|
1993-01-06 |
1994-12-20 |
Kirk; Mark P. |
Photothermographic materials
|
|
DK122693D0
(da)
|
1993-10-29 |
1993-10-29 |
Hempels Skibsfarve Fab J C |
Marin struktur
|
|
AUPM425294A0
(en)
|
1994-03-04 |
1994-03-31 |
Australian National University, The |
In-vitro angiogenesis assay
|
|
JPH08157461A
(ja)
|
1994-12-07 |
1996-06-18 |
Sankyo Co Ltd |
スルホン誘導体
|
|
US5576338A
(en)
|
1995-02-15 |
1996-11-19 |
Merck Frosst Canada, Inc. |
Bis (biaryl) compounds as inhibitors of leukotriene biosynthesis
|
|
US5624937A
(en)
|
1995-03-02 |
1997-04-29 |
Eli Lilly And Company |
Chemical compounds as inhibitors of amyloid beta protein production
|
|
AU3889097A
(en)
|
1996-08-01 |
1998-02-25 |
E.I. Du Pont De Nemours And Company |
Arthropodicidal and fungicidal cyclic amides
|
|
DE19638484A1
(de)
|
1996-09-20 |
1998-03-26 |
Basf Ag |
Hetaroylderivate
|
|
DE19638486A1
(de)
|
1996-09-20 |
1998-03-26 |
Basf Ag |
Hetaroylderivate
|
|
ZA986594B
(en)
|
1997-07-25 |
1999-01-27 |
Abbott Lab |
Urokinase inhibitors
|
|
US6258822B1
(en)
|
1997-08-06 |
2001-07-10 |
Abbott Laboratories |
Urokinase inhibitors
|
|
US6504031B1
(en)
|
1998-08-06 |
2003-01-07 |
Milan Bruncko |
Naphthamidine urokinase inhibitors
|
|
US6284796B1
(en)
|
1998-08-06 |
2001-09-04 |
Abbott Laboratories |
Ukokinase inhibitors
|
|
GB9819382D0
(en)
|
1998-09-04 |
1998-10-28 |
Cerebrus Ltd |
Chemical compounds I
|
|
GB9822450D0
(en)
|
1998-10-14 |
1998-12-09 |
Smithkline Beecham Plc |
Medicaments
|
|
GB9822440D0
(en)
|
1998-10-14 |
1998-12-09 |
Smithkline Beecham Plc |
Medicaments
|
|
US6927214B1
(en)
|
1999-01-15 |
2005-08-09 |
Novo Nordisk A/S |
Non-peptide GLP-1 agonists
|
|
US6639121B1
(en)
|
1999-07-29 |
2003-10-28 |
Dana-Farber Cancer Institute, Inc. |
Inducible cancer model to study the molecular basis of host tumor cell interactions in vivo
|
|
US6893812B2
(en)
|
2000-05-30 |
2005-05-17 |
Board Of Supervisors Of Louisiana State University And Agricultural And Mechanical College |
Three-dimensional ex vivo angiogenesis system
|
|
US6803369B1
(en)
|
2000-07-25 |
2004-10-12 |
Smithkline Beecham Corporation |
Compounds and methods for the treatment of neoplastic disease
|
|
CN1452619A
(zh)
|
2000-07-26 |
2003-10-29 |
史密斯克莱·比奇曼公司 |
具有抗细菌活性的氨基哌啶喹啉和它们的氮杂等排的类似物
|
|
US6576644B2
(en)
|
2000-09-06 |
2003-06-10 |
Bristol-Myers Squibb Co. |
Quinoline inhibitors of cGMP phosphodiesterase
|
|
EP1719770A3
(en)
|
2000-09-21 |
2008-03-05 |
Smithkline Beecham Plc |
Quinoline derivatives as antibacterials
|
|
JP4307070B2
(ja)
|
2000-11-17 |
2009-08-05 |
バイオモーダ・インコーポレーテツド |
５，１０，１５，２０−テトラキス（カルボキシフェニル）ポルフィンを使用する、細胞および組織サンプルにおける前がん症状を検出するための組成物および方法
|
|
GB0031088D0
(en)
|
2000-12-20 |
2001-01-31 |
Smithkline Beecham Plc |
Medicaments
|
|
GB0031086D0
(en)
|
2000-12-20 |
2001-01-31 |
Smithkline Beecham Plc |
Medicaments
|
|
GB0101577D0
(en)
|
2001-01-22 |
2001-03-07 |
Smithkline Beecham Plc |
Compounds
|
|
DE10110750A1
(de)
|
2001-03-07 |
2002-09-12 |
Bayer Ag |
Neuartige Aminodicarbonsäurederivate mit pharmazeutischen Eigenschaften
|
|
GB0112836D0
(en)
|
2001-05-25 |
2001-07-18 |
Smithkline Beecham Plc |
Medicaments
|
|
GB0112834D0
(en)
|
2001-05-25 |
2001-07-18 |
Smithkline Beecham Plc |
Medicaments
|
|
GB0118238D0
(en)
|
2001-07-26 |
2001-09-19 |
Smithkline Beecham Plc |
Medicaments
|
|
US20050261298A1
(en)
|
2002-01-18 |
2005-11-24 |
David Solow-Cordero |
Methods of treating conditions associated with an Edg-7 receptor
|
|
EP1541149A1
(en)
|
2002-06-26 |
2005-06-15 |
Kyowa Hakko Kogyo Co., Ltd. |
Phosphodiesterase inhibitor
|
|
GB0217294D0
(en)
|
2002-07-25 |
2002-09-04 |
Glaxo Group Ltd |
Medicaments
|
|
AU2003303956A1
(en)
|
2002-11-05 |
2004-11-23 |
Smithkline Beecham Corporation |
Antibacterial agents
|
|
TW200507841A
(en)
|
2003-03-27 |
2005-03-01 |
Glaxo Group Ltd |
Antibacterial agents
|
|
CN1856307A
(zh)
|
2003-09-23 |
2006-11-01 |
默克公司 |
喹啉钾通道抑制剂
|
|
JP2005126549A
(ja)
|
2003-10-23 |
2005-05-19 |
Konica Minolta Medical & Graphic Inc |
開始剤、組成物、ラジカル発生方法、平版印刷版作製用感光材料および平版印刷版の作製方法
|
|
JP2007516258A
(ja)
|
2003-12-12 |
2007-06-21 |
ワイス |
心臓血管の疾患治療に有用なキノリン誘導体
|
|
US20070254872A1
(en)
|
2004-07-08 |
2007-11-01 |
Glaxo Group Limited |
Antibacterial Agents
|
|
US20080194547A1
(en)
|
2004-07-09 |
2008-08-14 |
Glaxo Group Limited |
Antibacterial Agents
|
|
JP2008506695A
(ja)
|
2004-07-13 |
2008-03-06 |
グラクソ グループ リミテッド |
抗細菌剤
|
|
WO2006008644A1
(en)
|
2004-07-13 |
2006-01-26 |
Pfizer Products Inc. |
Antidiabetic compounds
|
|
UY29016A1
(es)
|
2004-07-20 |
2006-02-24 |
Boehringer Ingelheim Int |
Analogos de dipeptidos inhibidores de la hepatitis c
|
|
JP2008515960A
(ja)
|
2004-10-12 |
2008-05-15 |
アストラゼネカ アクチボラグ |
キノリン誘導体
|
|
WO2006081182A2
(en)
|
2005-01-25 |
2006-08-03 |
Glaxo Group Limited |
Antibacterial agents
|
|
JP2008528598A
(ja)
|
2005-01-25 |
2008-07-31 |
グラクソ グループ リミテッド |
抗菌剤
|
|
WO2006103120A2
(en)
|
2005-04-01 |
2006-10-05 |
Insa Rouen |
New heterocyclic compounds, their preparation and their use as medicaments, in particular as anti-alzheimer agents
|
|
US7732613B2
(en)
|
2005-09-14 |
2010-06-08 |
Bristol-Myers Squibb Company |
Met kinase inhibitors
|
|
US20090270371A1
(en)
|
2005-12-20 |
2009-10-29 |
Gyorgy Keseru |
Quinoline derivatives useful in the treatment of mglur5 receptor-mediated disorders
|
|
UY30183A1
(es)
|
2006-03-02 |
2007-10-31 |
Astrazeneca Ab |
Derivados de quinolina
|
|
EP1994028A1
(en)
|
2006-03-02 |
2008-11-26 |
AstraZeneca AB |
Quinoline derivatives for treating cancer
|
|
US20090076075A1
(en)
|
2006-03-02 |
2009-03-19 |
Frederic Henri Jung |
Quinoline derivatives
|
|
JP2009536613A
(ja)
|
2006-04-07 |
2009-10-15 |
ベーリンガー インゲルハイム インターナショナル ゲゼルシャフト ミット ベシュレンクテル ハフツング |
Ｃｂ２受容体を調節する化合物
|
|
WO2007138112A2
(en)
|
2006-06-01 |
2007-12-06 |
Devgen N.V. |
Compounds that interact with ion channels, in particular with ion channels from the kv family
|
|
WO2008010061A2
(en)
|
2006-07-17 |
2008-01-24 |
Glenmark Pharmaceuticals S.A. |
3-azabicyclo [3.1.0] hexane vanilloid receptor ligands, pharmaceutical compositions containing them, and processes for their preparation
|
|
TW200825054A
(en)
|
2006-10-18 |
2008-06-16 |
Wyeth Corp |
Quinoline compounds
|
|
EP2094307A4
(en)
|
2006-11-08 |
2015-08-26 |
Macrogenics West Inc |
TES7 AND THEREO BINDING ANTIBODIES
|
|
MX2009004947A
(es)
|
2006-11-09 |
2009-05-19 |
Hoffmann La Roche |
Arilsulfonil-pirrolidinas como inhibidores 5-hidroxitriptaminas6 (5-ht6).
|
|
TWI373467B
(en)
|
2007-01-11 |
2012-10-01 |
Academia Sinica |
New aniline or phenol mustrads linked to dna-affinic molecules or water-soluble aromatic rings and their use as cancer
|
|
WO2009008906A2
(en)
|
2007-02-06 |
2009-01-15 |
The Trustees Of The University Of Pennsylvania |
Therapeutic compounds for blocking dna synthesis of pox viruses
|
|
GB0704906D0
(en)
|
2007-03-14 |
2007-04-25 |
Syngenta Participations Ag |
Fungicides
|
|
EP2147310A4
(en)
|
2007-04-27 |
2010-09-08 |
Univ Rochester |
COMPOSITIONS AND METHODS OF INHIBITING G-PROTEIN SIGNALING
|
|
US7928111B2
(en)
|
2007-06-08 |
2011-04-19 |
Senomyx, Inc. |
Compounds including substituted thienopyrimidinone derivatives as ligands for modulating chemosensory receptors
|
|
US8063220B2
(en)
|
2007-06-22 |
2011-11-22 |
Richter Gedeon Nyrt. |
Sulfonyl-quinoline derivatives
|
|
WO2009019708A2
(en)
|
2007-08-09 |
2009-02-12 |
Urifer Ltd |
Pharmaceutical compositions and methods for the treatment of cancer
|
|
US8679836B2
(en)
|
2007-10-01 |
2014-03-25 |
The United States Of America, As Represented By The Secretary, Department Of Health And Human Services |
Methods of monitoring angiogenesis and metastasis in three dimensional co-cultures
|
|
WO2009082942A1
(en)
|
2007-12-19 |
2009-07-09 |
Ningbo Institute Of Materials Technology And Engineering, Chinese Academy Of Sciences |
Polythioetherimides and method for producing thereof
|
|
AU2008345225A1
(en)
|
2007-12-21 |
2009-07-09 |
University Of Rochester |
Method for altering the lifespan of eukaryotic organisms
|
|
DE102008010661A1
(de)
|
2008-02-22 |
2009-09-03 |
Dr. Felix Jäger und Dr. Stefan Drinkuth Laborgemeinschaft OHG |
Verfahren zur Herstellung von Pyridin-2-Boronsäure und Derivaten davon
|
|
US8008306B2
(en)
|
2008-04-30 |
2011-08-30 |
Kowa Company, Ltd. |
Quinoline compounds
|
|
CN102124000B
(zh)
|
2008-06-17 |
2014-09-17 |
阿斯利康(瑞典)有限公司 |
吡啶化合物
|
|
WO2011022216A1
(en)
|
2009-08-17 |
2011-02-24 |
High Point Pharmaceuticals, Llc |
Substituted pyridine derivatives, pharmaceutical compositions, and methods of use to treat oxidative stress
|
|
KR20120063515A
(ko)
|
2009-09-09 |
2012-06-15 |
아빌라 테라퓨틱스, 인크. |
Ｐｉ３ 키나제 억제제 및 이들의 용도
|
|
KR101748707B1
(ko)
|
2009-11-27 |
2017-06-20 |
삼성전자주식회사 |
ｃ-Ｍｅｔ에 특이적으로 결합하는 항체 및 그를 이용한 암 진단용 키트
|
|
CU24144B1
(es)
|
2010-01-04 |
2016-01-29 |
Nippon Soda Co |
Compuesto heterocíclico conteniendo nitrógeno y fungicida para el uso en agricultura y jardinería
|
|
US20130274215A1
(en)
|
2010-04-08 |
2013-10-17 |
Fate Therapeutics, Inc. |
Pharmaceutical compositions to treat fibrosis
|
|
TWI516264B
(zh)
|
2010-05-06 |
2016-01-11 |
臺北醫學大學 |
芳香醯喹啉化合物
|
|
AR081034A1
(es)
|
2010-05-11 |
2012-05-30 |
Sanofi Aventis |
Derivados de n-heteroaril tetrahidro-isoquinolina sustituidos, composiciones farmaceuticas que los contienen y uso de los mismos para el tratamiento de enfermedades del sistema nervioso central
|
|
US8883978B2
(en)
|
2010-05-11 |
2014-11-11 |
Institute For Cancer Research |
Antibodies to tumor endothelial marker 7R
|
|
WO2011156557A2
(en)
|
2010-06-11 |
2011-12-15 |
Thomas James B |
Compounds active at the neurotensin receptor
|
|
KR101195112B1
(ko)
|
2010-06-14 |
2012-10-29 |
인하대학교 산학협력단 |
암혈관내피세포의 분리방법 및 배양방법
|
|
EP2401915A1
(en)
|
2010-06-29 |
2012-01-04 |
Basf Se |
Pyrazolopyridine compounds
|
|
EP2402338A1
(en)
|
2010-06-29 |
2012-01-04 |
Basf Se |
Pyrazolopyridine compounds
|
|
EP2588471A1
(en)
|
2010-06-30 |
2013-05-08 |
Amgen Inc. |
Heterocyclic compounds and their use as inhibitors of pi3k activity
|
|
AU2011271462A1
(en)
|
2010-06-30 |
2013-01-10 |
Amgen Inc. |
Nitrogen containing heterocyclic compounds as PIK3 -delta inhibitors
|
|
CN103153096B
(zh)
|
2010-08-12 |
2016-08-03 |
赛诺米克斯公司 |
提高甜味增强剂的稳定性的方法和包含稳定的甜味增强剂的组合物
|
|
RU2443697C1
(ru)
|
2010-12-21 |
2012-02-27 |
Александр Васильевич Иващенко |
Замещенные метил-амины, антагонисты серотониновых 5-ht6 рецепторов, способы получения и применения
|
|
WO2012116237A2
(en)
|
2011-02-23 |
2012-08-30 |
Intellikine, Llc |
Heterocyclic compounds and uses thereof
|
|
US11179500B2
(en)
|
2011-02-24 |
2021-11-23 |
Emory University |
JAB1 inhibitory compositions for ossification and methods related thereto
|
|
JP2014522570A
(ja)
|
2011-05-31 |
2014-09-04 |
メルク パテント ゲゼルシャフト ミット ベシュレンクテル ハフツング |
電解質配合物
|
|
WO2013020909A1
(en)
|
2011-08-05 |
2013-02-14 |
Institut National De La Sante Et De La Recherche Medicale (Inserm) |
Materials and methods for the treatment of tauopathies
|
|
US9586964B2
(en)
|
2011-10-28 |
2017-03-07 |
Vanderbilt University |
Substituted 2-(4-heterocyclylbenzyl)isoindolin-1-one analogs as positive allosteric modulators of the muscarinic acetylcholine receptor M1
|
|
CN102516232A
(zh)
|
2011-12-14 |
2012-06-27 |
无锡美克赛医药科技有限公司 |
一种ErbB2的小分子选择性抑制剂及其应用
|
|
WO2013158928A2
(en)
|
2012-04-18 |
2013-10-24 |
Elcelyx Therapeutics, Inc. |
Chemosensory receptor ligand-based therapies
|
|
WO2013188813A2
(en)
|
2012-06-15 |
2013-12-19 |
The Regents Of The University Of California |
Novel therapeutics for brain cancer
|
|
CN104812389B
(zh)
|
2012-09-24 |
2020-07-17 |
润新生物公司 |
某些化学实体、组合物及方法
|
|
KR102000211B1
(ko)
|
2012-10-29 |
2019-09-30 |
삼성디스플레이 주식회사 |
유기금속 화합물 및 이를 포함한 유기 발광 소자
|
|
US20160155575A1
(en)
|
2013-07-25 |
2016-06-02 |
Basf Se |
Methine dyes with large organic counter anion for dye sensitized solar cells
|
|
WO2015114660A1
(en)
|
2014-01-24 |
2015-08-06 |
Cadila Healtchare Limited |
Novel heterobicyclic compounds as kappa opioid agonists
|
|
US9573950B2
(en)
|
2014-03-14 |
2017-02-21 |
Abbvie Deutschland Gmbh & Co Kg |
Substituted [1,4]diazepino[6,7,1-ij]quinolines as serotonin 5-HT2C receptor modulators
|
|
EP2982667A1
(en)
|
2014-08-04 |
2016-02-10 |
Fraunhofer Gesellschaft zur Förderung der angewandten Forschung e.V. |
Competitive PPAR-gamma antagonists
|
|
US20170281611A1
(en)
|
2014-08-29 |
2017-10-05 |
Eiger Biopharmaceuticals, Inc. |
Quinolines and their use for treating endoplasmic reticulum stress-caused diseases
|
|
TWI745284B
(zh)
|
2015-01-22 |
2021-11-11 |
南韓商艾瑞多斯公司 |
化合物、彼之製法、及含彼之著色劑
|
|
WO2016140803A1
(en)
|
2015-03-03 |
2016-09-09 |
The Trustees Of The University Of Pennsylvania |
Direct mapping of local director field of nematic liquid crystals at the nanoscale
|
|
JP2016162983A
(ja)
|
2015-03-04 |
2016-09-05 |
ダイキン工業株式会社 |
エッチング処理用組成物及びエッチング処理方法
|
|
BR112018001424B1
(pt)
|
2015-07-30 |
2024-02-06 |
Calgent Biotechnology Co., Ltd |
Compostos, composição farmacêutica e usos de um composto
|
|
AR106515A1
(es)
|
2015-10-29 |
2018-01-24 |
Bayer Cropscience Ag |
Sililfenoxiheterociclos trisustituidos y análogos
|
|
US10501549B2
(en)
|
2015-11-30 |
2019-12-10 |
Seoul National University R&Db Foundation |
Methods of inhibiting pathological angiogenesis with doppel-targeting molecules
|
|
MX2021006804A
(es)
|
2015-12-17 |
2023-01-13 |
Merck Patent Gmbh |
Antagonistas policiclicos del receptor 7/8 tipo toll (tlr7/8) y uso de los mismos en el tratamiento de trastornos inmunitarios.
|
|
TWI804987B
(zh)
|
2015-12-24 |
2023-06-11 |
日商協和麒麟股份有限公司 |
α、β不飽和醯胺化合物
|
|
WO2017189715A1
(en)
|
2016-04-26 |
2017-11-02 |
Northwestern University |
Modified pigment epithelium-derived factor (pedf) peptides and uses thereof for treating neovascular diseases, inflammatory diseases, cancer, and for cytoprotection
|
|
US20190309264A1
(en)
|
2016-08-15 |
2019-10-10 |
Organovo, Inc. |
Three Dimensional Bioprinted Tumor Models for Drug Testing
|
|
TW201825465A
(zh)
|
2016-09-23 |
2018-07-16 |
美商基利科學股份有限公司 |
磷脂醯肌醇3-激酶抑制劑
|
|
TW201813963A
(zh)
|
2016-09-23 |
2018-04-16 |
美商基利科學股份有限公司 |
磷脂醯肌醇3-激酶抑制劑
|
|
WO2018068357A1
(zh)
|
2016-10-13 |
2018-04-19 |
西华大学 |
一类新型sirt2蛋白抑制剂及其在制药中的用途
|
|
PL3558321T3
(pl)
|
2016-12-23 |
2023-10-23 |
Felicitex Therapeutics, Inc. |
Pochodne chinolin jako inhibitory kinaz dyrk1a i/lub dyrk1b
|
|
CN108884061B
(zh)
|
2017-01-13 |
2021-11-16 |
江苏恒瑞医药股份有限公司 |
1,2,4-三嗪-3-胺类衍生物、其制备方法及其在医药上的应用
|
|
WO2018200592A1
(en)
|
2017-04-24 |
2018-11-01 |
Regents Of The University Of California |
Biosynthesis of bioorthogonal amino acids
|
|
BR112019023030A2
(pt)
|
2017-05-03 |
2020-06-02 |
Bayer Aktiengesellschaft |
Sililmetilfenoxiquinolinas trissubstituídas e análogos
|
|
CN109422754A
(zh)
|
2017-08-24 |
2019-03-05 |
上海迪诺医药科技有限公司 |
吡唑并[3,4-d]嘧啶-3-酮衍生物、其药物组合物及应用
|
|
WO2019173482A1
(en)
|
2018-03-06 |
2019-09-12 |
Sanford Burnham Prebys Medical Discovery Institute |
4-aminoquinoline compounds for the treatment of angiogenesis
|
|
US20210147525A1
(en)
|
2019-10-18 |
2021-05-20 |
The Regents Of The University Of California |
Methods and compositions for treating pathogenic blood vessel disorders
|
|
US11884647B2
(en)
|
2019-10-18 |
2024-01-30 |
The Regents Of The University Of California |
Compounds and methods for targeting pathogenic blood vessels
|
|
EP4045910A1
(en)
|
2019-10-18 |
2022-08-24 |
The Regents of the University of California |
Compositions and methods for detecting plxdc1 and plxdc2 in human tissues
|
|
US12590298B2
(en)
|
2019-10-18 |
2026-03-31 |
The Regents Of The University Of California |
Ex vivo tumor angiogenesis model
|