JP2021534124A5 - - Google Patents

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Publication number
JP2021534124A5
JP2021534124A5 JP2021506929A JP2021506929A JP2021534124A5 JP 2021534124 A5 JP2021534124 A5 JP 2021534124A5 JP 2021506929 A JP2021506929 A JP 2021506929A JP 2021506929 A JP2021506929 A JP 2021506929A JP 2021534124 A5 JP2021534124 A5 JP 2021534124A5
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JP2021534124A (ja
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Priority claimed from PCT/US2019/045903 external-priority patent/WO2020033828A1/en
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JP2021506929A 2018-08-10 2019-08-09 癌治療用ptpn11(shp2)阻害剤としての6−(4−アミノ−3−メチル−2−オキサ−8−アザスピロ[4.5]デカン−8−イル)−3−(2,3−ジクロロフェニル)−2−メチルピリミジン−4(3h)−オン誘導体及び関連化合物 Ceased JP2021534124A (ja)

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JP2023132960A JP7579402B2 (ja) 2018-08-10 2023-08-17 癌治療用ptpn11(shp2)阻害剤としての6-(4-アミノ-3-メチル-2-オキサ-8-アザスピロ[4.5]デカン-8-イル)-3-(2,3-ジクロロフェニル)-2-メチルピリミジン-4(3h)-オン誘導体及び関連化合物

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
US201862717588P 2018-08-10 2018-08-10
US62/717,588 2018-08-10
US201862773921P 2018-11-30 2018-11-30
US62/773,921 2018-11-30
PCT/US2019/045903 WO2020033828A1 (en) 2018-08-10 2019-08-09 6-(4-amino-3-methyl-2-oxa-8-azaspiro[4.5]decan-8-yl)-3-(2,3-dichlorophenyl)-2-methylpyrimidin-4(3h)-one derivatives and related compounds as ptpn11 (shp2) inhibitors for treating cancer

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JP2023132960A Division JP7579402B2 (ja) 2018-08-10 2023-08-17 癌治療用ptpn11(shp2)阻害剤としての6-(4-アミノ-3-メチル-2-オキサ-8-アザスピロ[4.5]デカン-8-イル)-3-(2,3-ジクロロフェニル)-2-メチルピリミジン-4(3h)-オン誘導体及び関連化合物

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JP2021534124A JP2021534124A (ja) 2021-12-09
JP2021534124A5 true JP2021534124A5 (enExample) 2022-08-18

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JP2021506929A Ceased JP2021534124A (ja) 2018-08-10 2019-08-09 癌治療用ptpn11(shp2)阻害剤としての6−(4−アミノ−3−メチル−2−オキサ−8−アザスピロ[4.5]デカン−8−イル)−3−(2,3−ジクロロフェニル)−2−メチルピリミジン−4(3h)−オン誘導体及び関連化合物
JP2023132960A Active JP7579402B2 (ja) 2018-08-10 2023-08-17 癌治療用ptpn11(shp2)阻害剤としての6-(4-アミノ-3-メチル-2-オキサ-8-アザスピロ[4.5]デカン-8-イル)-3-(2,3-ジクロロフェニル)-2-メチルピリミジン-4(3h)-オン誘導体及び関連化合物

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JP2023132960A Active JP7579402B2 (ja) 2018-08-10 2023-08-17 癌治療用ptpn11(shp2)阻害剤としての6-(4-アミノ-3-メチル-2-オキサ-8-アザスピロ[4.5]デカン-8-イル)-3-(2,3-ジクロロフェニル)-2-メチルピリミジン-4(3h)-オン誘導体及び関連化合物

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US (3) US11104675B2 (enExample)
EP (2) EP3833670B1 (enExample)
JP (2) JP2021534124A (enExample)
KR (1) KR102707409B1 (enExample)
CN (1) CN112601750B (enExample)
AU (1) AU2019319971B2 (enExample)
BR (1) BR112021002327A2 (enExample)
CA (1) CA3109181A1 (enExample)
CL (1) CL2021000355A1 (enExample)
CO (1) CO2021003074A2 (enExample)
CR (1) CR20210132A (enExample)
DK (1) DK3833670T3 (enExample)
ES (1) ES2981592T3 (enExample)
FI (1) FI3833670T3 (enExample)
HR (1) HRP20240861T1 (enExample)
HU (1) HUE067297T2 (enExample)
IL (2) IL307361B2 (enExample)
LT (1) LT3833670T (enExample)
MX (2) MX2021001608A (enExample)
PE (1) PE20211050A1 (enExample)
PH (1) PH12021550268A1 (enExample)
PL (1) PL3833670T3 (enExample)
PT (1) PT3833670T (enExample)
RS (1) RS65728B1 (enExample)
SA (1) SA521421205B1 (enExample)
SG (1) SG11202100199UA (enExample)
SI (1) SI3833670T1 (enExample)
SM (1) SMT202400192T1 (enExample)
TW (1) TWI827646B (enExample)
UA (1) UA128559C2 (enExample)
WO (1) WO2020033828A1 (enExample)
ZA (1) ZA202101449B (enExample)

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