JP2022543420A5 - - Google Patents

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Publication number
JP2022543420A5
JP2022543420A5 JP2022506948A JP2022506948A JP2022543420A5 JP 2022543420 A5 JP2022543420 A5 JP 2022543420A5 JP 2022506948 A JP2022506948 A JP 2022506948A JP 2022506948 A JP2022506948 A JP 2022506948A JP 2022543420 A5 JP2022543420 A5 JP 2022543420A5
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JP
Japan
Application number
JP2022506948A
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Japanese (ja)
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JP2022543420A (ja
JPWO2021026520A5 (https=
JP7636004B2 (ja
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Priority claimed from PCT/US2020/045566 external-priority patent/WO2021026520A1/en
Publication of JP2022543420A publication Critical patent/JP2022543420A/ja
Publication of JP2022543420A5 publication Critical patent/JP2022543420A5/ja
Publication of JPWO2021026520A5 publication Critical patent/JPWO2021026520A5/ja
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JP2022506948A 2019-08-08 2020-08-10 アムホテリシンbのハイブリッドアミド誘導体 Active JP7636004B2 (ja)

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
US201962884464P 2019-08-08 2019-08-08
US62/884,464 2019-08-08
US201962951753P 2019-12-20 2019-12-20
US62/951,753 2019-12-20
PCT/US2020/045566 WO2021026520A1 (en) 2019-08-08 2020-08-10 Hybrid amide derivatives of amphotericin b

Publications (4)

Publication Number Publication Date
JP2022543420A JP2022543420A (ja) 2022-10-12
JP2022543420A5 true JP2022543420A5 (https=) 2023-08-14
JPWO2021026520A5 JPWO2021026520A5 (https=) 2023-08-14
JP7636004B2 JP7636004B2 (ja) 2025-02-26

Family

ID=74503735

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Application Number Title Priority Date Filing Date
JP2022506948A Active JP7636004B2 (ja) 2019-08-08 2020-08-10 アムホテリシンbのハイブリッドアミド誘導体

Country Status (12)

Country Link
US (1) US20230016424A1 (https=)
EP (1) EP4009985A4 (https=)
JP (1) JP7636004B2 (https=)
KR (1) KR20220071185A (https=)
CN (1) CN114555094A (https=)
AU (1) AU2020325163B2 (https=)
BR (1) BR112022001866A2 (https=)
CA (1) CA3149916A1 (https=)
CL (1) CL2022000319A1 (https=)
IL (1) IL290289B2 (https=)
MX (1) MX2022001678A (https=)
WO (1) WO2021026520A1 (https=)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
PH12022551513A1 (en) 2019-12-20 2023-04-24 Mirati Therapeutics Inc Sos1 inhibitors
US20230357303A1 (en) * 2020-08-10 2023-11-09 The Board Of Trustees Of The University Of Illinois Hybrid amide derivatives of amphotericin b
CN115536716B (zh) * 2021-06-29 2025-08-08 中国科学院上海药物研究所 两性霉素b半合成衍生物及其制备方法和用途
TW202519239A (zh) * 2023-07-19 2025-05-16 美國伊利諾大學理事會 利用遺失蛋白質(missing proteins)之小分子模擬物恢復生理機能
GB202406857D0 (en) * 2024-05-15 2024-06-26 Univ Manchester Polyenes

Family Cites Families (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
PL122086B1 (en) * 1979-04-09 1982-06-30 Politechnika Gdanska Process for preparing amides of antibiotics from the group of polyene macrolides and their derivativesvykh makrolidov i ikh proizvodnykh
FR2776927B1 (fr) * 1998-04-07 2002-07-05 Univ Paris Curie Compositions pour la vectorisation de molecules
US6664241B2 (en) * 2000-05-31 2003-12-16 Micrologix Biotech Inc. Water-soluble amide derivatives of polyene macrolides and preparation and uses thereof
MX365184B (es) * 2010-12-21 2019-05-21 Centro De Investig Y De Estudios Avanzados Del I P N Nuevos compuestos analogos de la anfotericina y composiciones farmaceuticas que los contienen.
KR20150027217A (ko) * 2012-06-15 2015-03-11 블러트 에스.에이. 항진균성 항생 암포테리신 b의 n-치환된 제2 세대 유도체, 및 이의 제조 및 응용 방법
WO2015164289A1 (en) 2014-04-21 2015-10-29 Cidara Therapeutics, Inc. Compositions and methods for the treatment of fungal infections
JP6543272B2 (ja) * 2014-05-16 2019-07-10 ザ ボード オブ トラスティーズ オブ ザ ユニヴァーシティ オブ イリノイThe Board Of Trustees Of The University Of Illinois 低減された毒性を有するアンホテリシンb誘導体
TWI702223B (zh) 2014-06-12 2020-08-21 日商塩野義製藥股份有限公司 多烯巨環內酯衍生物
AU2016205187B2 (en) 2015-01-08 2020-02-27 The Board Of Trustees Of The University Of Illinois Concise synthesis of urea derivatives of amphotericin B
CA3021061C (en) * 2015-04-15 2023-10-24 Martin D. Burke Derivatives of amphotericin b
US10322187B2 (en) * 2015-08-10 2019-06-18 Lehigh University Reduced toxicity molecular conjugates of anti-fungal agents
RU2688658C1 (ru) * 2018-04-10 2019-05-22 Федеральное государственное бюджетное научное учреждение "Научно-исследовательский институт по изысканию новых антибиотиков имени Г.Ф. Гаузе" Противогрибковый полусинтетический полиеновый антибиотик, его водорастворимые соли и фармацевтические композиции на их основе

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