JP2022543420A5 - - Google Patents
Info
- Publication number
- JP2022543420A5 JP2022543420A5 JP2022506948A JP2022506948A JP2022543420A5 JP 2022543420 A5 JP2022543420 A5 JP 2022543420A5 JP 2022506948 A JP2022506948 A JP 2022506948A JP 2022506948 A JP2022506948 A JP 2022506948A JP 2022543420 A5 JP2022543420 A5 JP 2022543420A5
- Authority
- JP
- Japan
- Prior art keywords
- unsubstituted
- substituted
- compound according
- alkyl
- hydrogen
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
Applications Claiming Priority (5)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201962884464P | 2019-08-08 | 2019-08-08 | |
| US62/884,464 | 2019-08-08 | ||
| US201962951753P | 2019-12-20 | 2019-12-20 | |
| US62/951,753 | 2019-12-20 | ||
| PCT/US2020/045566 WO2021026520A1 (en) | 2019-08-08 | 2020-08-10 | Hybrid amide derivatives of amphotericin b |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2022543420A JP2022543420A (ja) | 2022-10-12 |
| JP2022543420A5 true JP2022543420A5 (https=) | 2023-08-14 |
| JP7636004B2 JP7636004B2 (ja) | 2025-02-26 |
Family
ID=74503735
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2022506948A Active JP7636004B2 (ja) | 2019-08-08 | 2020-08-10 | アムホテリシンｂのハイブリッドアミド誘導体 |
Country Status (12)
| Country | Link |
|---|---|
| US (1) | US20230016424A1 (https=) |
| EP (1) | EP4009985A4 (https=) |
| JP (1) | JP7636004B2 (https=) |
| KR (1) | KR20220071185A (https=) |
| CN (1) | CN114555094A (https=) |
| AU (1) | AU2020325163B2 (https=) |
| BR (1) | BR112022001866A2 (https=) |
| CA (1) | CA3149916A1 (https=) |
| CL (1) | CL2022000319A1 (https=) |
| IL (1) | IL290289B2 (https=) |
| MX (1) | MX2022001678A (https=) |
| WO (1) | WO2021026520A1 (https=) |
Families Citing this family (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| PH12022551513A1 (en) | 2019-12-20 | 2023-04-24 | Mirati Therapeutics Inc | Sos1 inhibitors |
| AU2021325676A1 (en) * | 2020-08-10 | 2023-03-30 | The Board Of Trustees Of The University Of Illinois | Hybrid amide derivatives of amphotericin B |
| CN115536716B (zh) * | 2021-06-29 | 2025-08-08 | 中国科学院上海药物研究所 | 两性霉素b半合成衍生物及其制备方法和用途 |
| TW202519239A (zh) * | 2023-07-19 | 2025-05-16 | 美國伊利諾大學理事會 | 利用遺失蛋白質（ｍｉｓｓｉｎｇ ｐｒｏｔｅｉｎｓ）之小分子模擬物恢復生理機能 |
| GB202406857D0 (en) * | 2024-05-15 | 2024-06-26 | Univ Manchester | Polyenes |
Family Cites Families (13)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| PL122086B1 (en) * | 1979-04-09 | 1982-06-30 | Politechnika Gdanska | Process for preparing amides of antibiotics from the group of polyene macrolides and their derivativesvykh makrolidov i ikh proizvodnykh |
| FR2776927B1 (fr) * | 1998-04-07 | 2002-07-05 | Univ Paris Curie | Compositions pour la vectorisation de molecules |
| US6664241B2 (en) * | 2000-05-31 | 2003-12-16 | Micrologix Biotech Inc. | Water-soluble amide derivatives of polyene macrolides and preparation and uses thereof |
| MX365184B (es) * | 2010-12-21 | 2019-05-21 | Centro De Investig Y De Estudios Avanzados Del I P N | Nuevos compuestos analogos de la anfotericina y composiciones farmaceuticas que los contienen. |
| KR20150027217A (ko) * | 2012-06-15 | 2015-03-11 | 블러트 에스.에이. | 항진균성 항생 암포테리신 b의 n-치환된 제2 세대 유도체, 및 이의 제조 및 응용 방법 |
| WO2015164289A1 (en) * | 2014-04-21 | 2015-10-29 | Cidara Therapeutics, Inc. | Compositions and methods for the treatment of fungal infections |
| ES2749927T3 (es) * | 2014-05-16 | 2020-03-24 | Univ Illinois | Derivado de anfotericina b con toxicidad reducida |
| MA39568A1 (fr) * | 2014-06-12 | 2017-09-29 | Shionogi & Co | Dérivé de macrolide de polyène |
| WO2016112260A1 (en) * | 2015-01-08 | 2016-07-14 | The Board Of Trustees Of The University Of Illinois | Concise synthesis of urea derivatives of amphotericin b |
| JP7240811B2 (ja) * | 2015-04-15 | 2023-03-16 | スファンガ セラピューティクス インコーポレイテッド | アムホテリシンｂの誘導体 |
| US10322187B2 (en) * | 2015-08-10 | 2019-06-18 | Lehigh University | Reduced toxicity molecular conjugates of anti-fungal agents |
| RU2688658C1 (ru) * | 2018-04-10 | 2019-05-22 | Федеральное государственное бюджетное научное учреждение "Научно-исследовательский институт по изысканию новых антибиотиков имени Г.Ф. Гаузе" | Противогрибковый полусинтетический полиеновый антибиотик, его водорастворимые соли и фармацевтические композиции на их основе |
| TW202415384A (zh) * | 2022-06-24 | 2024-04-16 | 美國伊利諾大學理事會 | 雙性黴素b之複合醯胺衍生物於dsgpeg2k微胞中之調配物 |
-
2020
- 2020-08-10 EP EP20850514.9A patent/EP4009985A4/en active Pending
- 2020-08-10 MX MX2022001678A patent/MX2022001678A/es unknown
- 2020-08-10 US US17/633,254 patent/US20230016424A1/en active Pending
- 2020-08-10 CN CN202080070120.2A patent/CN114555094A/zh active Pending
- 2020-08-10 IL IL290289A patent/IL290289B2/en unknown
- 2020-08-10 WO PCT/US2020/045566 patent/WO2021026520A1/en not_active Ceased
- 2020-08-10 CA CA3149916A patent/CA3149916A1/en active Pending
- 2020-08-10 KR KR1020227007294A patent/KR20220071185A/ko active Pending
- 2020-08-10 JP JP2022506948A patent/JP7636004B2/ja active Active
- 2020-08-10 BR BR112022001866A patent/BR112022001866A2/pt unknown
- 2020-08-10 AU AU2020325163A patent/AU2020325163B2/en active Active
-
2022
- 2022-02-07 CL CL2022000319A patent/CL2022000319A1/es unknown
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