JP2001510181A5 - - Google Patents

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Publication number
JP2001510181A5
JP2001510181A5 JP2000503054A JP2000503054A JP2001510181A5 JP 2001510181 A5 JP2001510181 A5 JP 2001510181A5 JP 2000503054 A JP2000503054 A JP 2000503054A JP 2000503054 A JP2000503054 A JP 2000503054A JP 2001510181 A5 JP2001510181 A5 JP 2001510181A5
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JP
Japan
Prior art keywords
polyamine
amino
polyamine analog
alkyl
analog
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
JP2000503054A
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English (en)
Japanese (ja)
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JP4044728B2 (ja
JP2001510181A (ja
Filing date
Publication date
Application filed filed Critical
Priority claimed from PCT/US1998/014896 external-priority patent/WO1999003823A2/en
Publication of JP2001510181A publication Critical patent/JP2001510181A/ja
Publication of JP2001510181A5 publication Critical patent/JP2001510181A5/ja
Application granted granted Critical
Publication of JP4044728B2 publication Critical patent/JP4044728B2/ja
Anticipated expiration legal-status Critical
Expired - Fee Related legal-status Critical Current

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JP2000503054A 1997-07-15 1998-07-15 治療および診断薬剤としての新規なポリアミンアナログ Expired - Fee Related JP4044728B2 (ja)

Applications Claiming Priority (7)

Application Number Priority Date Filing Date Title
US5258697P 1997-07-15 1997-07-15
US60/052,586 1997-07-15
US6572897P 1997-11-14 1997-11-14
US60/065,728 1997-11-14
US8553898P 1998-05-15 1998-05-15
US60/085,538 1998-05-15
PCT/US1998/014896 WO1999003823A2 (en) 1997-07-15 1998-07-15 Novel polyamine analogues as therapeutic and diagnostic agents

Publications (3)

Publication Number Publication Date
JP2001510181A JP2001510181A (ja) 2001-07-31
JP2001510181A5 true JP2001510181A5 (https=) 2005-10-27
JP4044728B2 JP4044728B2 (ja) 2008-02-06

Family

ID=27368228

Family Applications (1)

Application Number Title Priority Date Filing Date
JP2000503054A Expired - Fee Related JP4044728B2 (ja) 1997-07-15 1998-07-15 治療および診断薬剤としての新規なポリアミンアナログ

Country Status (6)

Country Link
US (2) US6172261B1 (https=)
EP (1) EP1001927A2 (https=)
JP (1) JP4044728B2 (https=)
AU (1) AU758570B2 (https=)
CA (1) CA2297413A1 (https=)
WO (1) WO1999003823A2 (https=)

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US7432302B2 (en) * 2001-01-08 2008-10-07 Mediquest Therapeutics, Inc. Composition containing polyamine transport inhibitor and use thereof
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USRE43327E1 (en) 2001-01-08 2012-04-24 Aminex Therapeutics, Inc. Hydrophobic polyamine analogs and methods for their use
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JP2005510524A (ja) * 2001-11-16 2005-04-21 アルス・セラピー・デベロツプメント・フアンデーシヨン・インコーポレーテツド ポリアミン経路の調節による神経変性障害の治療
US20030129208A1 (en) * 2002-01-07 2003-07-10 Alberts David S. Topical application of alpha-DFMO and anti-inflammatory drug for treatment of actinic keratoses
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WO2003066572A1 (en) 2002-02-07 2003-08-14 Wisconsin Alumni Research Foundation Polyamine compounds and compositions for use in conjunction with cancer therapy
WO2004073701A1 (ja) * 2003-02-19 2004-09-02 Kuniyasu Soda Lfa-1抑制剤、及びその用途
US7314959B2 (en) * 2003-08-07 2008-01-01 Wisconsin Alumni Research Foundation Amino thiol compounds and compositions for use in conjunction with cancer therapy
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CN1980629B (zh) * 2004-06-14 2010-06-16 荷兰联合利华有限公司 减少皮脂生成和缩小毛孔大小的方法
US7740875B2 (en) * 2004-10-08 2010-06-22 Mediquest Therapeutics, Inc. Organo-gel formulations for therapeutic applications
US20060078580A1 (en) * 2004-10-08 2006-04-13 Mediquest Therapeutics, Inc. Organo-gel formulations for therapeutic applications
US7199267B1 (en) * 2005-10-21 2007-04-03 Mediquest Therapeutics, Inc. Recognition of oligiosaccaride molecular targets by polycationic small molecule inhibitors and treatment of immunological disorders and infectious diseases
US7411002B2 (en) 2006-06-07 2008-08-12 The University Of Kansas Polycationic sulfonamides and use thereof
EP2096106B1 (en) * 2006-11-15 2014-06-18 Nihon University Novel polyamine derivatives
US8497398B1 (en) * 2007-05-02 2013-07-30 University Of Central Florida Research Foundation, Inc. Polyamine transporter selective compounds as anti-cancer agents
FR2919287B1 (fr) * 2007-07-26 2012-10-12 Pf Medicament Nouveaux derives fluorescents de polyamines, leur procede de preparation et leurs applications en tant qu'outils de diagnostic dans le traitement des tumeurs cancereuses.
WO2009032321A2 (en) * 2007-09-06 2009-03-12 Genaera Corporation A method for treating diabetes
US9285320B2 (en) * 2008-05-01 2016-03-15 University Of Central Florida Research Foundation, Inc. Fluorescent cytotoxic compounds specific for the cellular polyamine transport system
GB0904842D0 (en) * 2009-03-20 2009-05-06 Univ Nottingham Protein labelling
JP6112449B2 (ja) 2009-07-16 2017-04-12 パソロジカ エルエルシー Ｍｇｂｇを含む経口送達用の医薬品および疾患を処置する方法
FR2967675B1 (fr) * 2010-11-24 2015-02-27 Pf Medicament Derives fluorescents de cyanines polyamines en tant que sonde de diagnostic
CN109432073A (zh) 2013-01-08 2019-03-08 帕萨罗杰卡有限公司 Mgbg在制备治疗或预防进行性ms及其进展的药物中的用途
JP6670503B2 (ja) * 2014-09-24 2020-03-25 国立大学法人弘前大学 生体由来細胞を用いたがん細胞の検出方法
CN108135929B (zh) 2015-09-02 2021-10-12 梅特罗诺姆中国Ip控股公司 使用光-酶分析物传感器进行连续健康监测的系统和方法
HUE052620T2 (hu) 2016-03-25 2021-05-28 Aminex Therapeutics Inc Biológiailag hozzáférhetõ poliaminok
WO2018111934A1 (en) * 2016-12-12 2018-06-21 University Of South Florida Polyamine compounds targeting the efflux pumps of multi-drug resistant bacterial pathogens and methods of using the same
US11905268B2 (en) 2018-08-10 2024-02-20 University Of Central Florida Research Foundation, Inc. Anthranilic acid derivatives and their use in the treatment of human cancers
JP2023545674A (ja) 2020-09-30 2023-10-31 アミネックス セラピューティクス， インコーポレイテッド ポリアミン輸送阻害剤およびｄｆｍｏの配合原薬
CN115074118B (zh) * 2022-06-27 2024-10-18 山东理工大学 一种基于芘基荧光探针分子的对硝基苯胺检测方法
CN118541146B (zh) * 2022-12-23 2025-04-25 中国医学科学院基础医学研究所 精胺衍生物及其在疾病中的治疗用途
US12605349B2 (en) 2024-09-05 2026-04-21 Orbus Therapeutics, Inc. Methods of treating grade 3 astrocytoma

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JP4094230B2 (ja) 1999-02-05 2008-06-04 メディクエスト セラピューティックス インク アンチザイムモジュレーターおよびその使用

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