JP2022534794A - 関節リウマチを有する対象における疼痛を治療するための組成物および方法 - Google Patents

関節リウマチを有する対象における疼痛を治療するための組成物および方法 Download PDF

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JP2022534794A
JP2022534794A JP2021572280A JP2021572280A JP2022534794A JP 2022534794 A JP2022534794 A JP 2022534794A JP 2021572280 A JP2021572280 A JP 2021572280A JP 2021572280 A JP2021572280 A JP 2021572280A JP 2022534794 A JP2022534794 A JP 2022534794A
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antibody
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JP2022534794A5 (https=
Inventor
ステファノ・フィオーレ
スーザン・ボクレイジ
トシオ・キムラ
グレゴリー・セント・ジョン
ウェンフイ・ウェイ
ヴィヴィアン・バイカーク
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Regeneron Pharmaceuticals Inc
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Regeneron Pharmaceuticals Inc
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Priority to JP2025061581A priority Critical patent/JP2025134086A/ja
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    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies
    • C07K16/18—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/28—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
    • C07K16/2866—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against receptors for cytokines, lymphokines, interferons
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0019—Injectable compositions; Intramuscular, intravenous, arterial, subcutaneous administration; Compositions to be administered through the skin in an invasive manner
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies
    • C07K16/18—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/24—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans against cytokines, lymphokines or interferons
    • C07K16/241—Tumor Necrosis Factors
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/505—Medicinal preparations containing antigens or antibodies comprising antibodies
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/545—Medicinal preparations containing antigens or antibodies characterised by the dose, timing or administration schedule
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/20—Immunoglobulins specific features characterized by taxonomic origin
    • C07K2317/21—Immunoglobulins specific features characterized by taxonomic origin from primates, e.g. man
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/50—Immunoglobulins specific features characterized by immunoglobulin fragments
    • C07K2317/56—Immunoglobulins specific features characterized by immunoglobulin fragments variable (Fv) region, i.e. VH and/or VL
    • C07K2317/565—Complementarity determining region [CDR]
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/70—Immunoglobulins specific features characterized by effect upon binding to a cell or to an antigen
    • C07K2317/76—Antagonist effect on antigen, e.g. neutralization or inhibition of binding

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  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Immunology (AREA)
  • Genetics & Genomics (AREA)
  • Biophysics (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Biochemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Rheumatology (AREA)
  • Pain & Pain Management (AREA)
  • Dermatology (AREA)
  • Epidemiology (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
JP2021572280A 2019-06-04 2020-06-03 関節リウマチを有する対象における疼痛を治療するための組成物および方法 Pending JP2022534794A (ja)

Priority Applications (1)

Application Number Priority Date Filing Date Title
JP2025061581A JP2025134086A (ja) 2019-06-04 2025-04-03 関節リウマチを有する対象における疼痛を治療するための組成物および方法

Applications Claiming Priority (7)

Application Number Priority Date Filing Date Title
US201962857247P 2019-06-04 2019-06-04
US62/857,247 2019-06-04
US201962930966P 2019-11-05 2019-11-05
US62/930,966 2019-11-05
EP20305191.7 2020-02-27
EP20305191 2020-02-27
PCT/US2020/035871 WO2020247461A1 (en) 2019-06-04 2020-06-03 Compositions and methods for treating pain in subj ects with rheumatoid arthritis

Related Child Applications (1)

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JP2025061581A Division JP2025134086A (ja) 2019-06-04 2025-04-03 関節リウマチを有する対象における疼痛を治療するための組成物および方法

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JP2022534794A true JP2022534794A (ja) 2022-08-03
JP2022534794A5 JP2022534794A5 (https=) 2023-06-07

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JP2021572280A Pending JP2022534794A (ja) 2019-06-04 2020-06-03 関節リウマチを有する対象における疼痛を治療するための組成物および方法
JP2025061581A Pending JP2025134086A (ja) 2019-06-04 2025-04-03 関節リウマチを有する対象における疼痛を治療するための組成物および方法

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US (2) US12297279B2 (https=)
EP (1) EP3980459A1 (https=)
JP (2) JP2022534794A (https=)
KR (1) KR20230061198A (https=)
CN (1) CN115667301A (https=)
AU (1) AU2020288561A1 (https=)
BR (1) BR112021024445A2 (https=)
CA (1) CA3142710A1 (https=)
CO (1) CO2021017737A2 (https=)
IL (1) IL288573A (https=)
MA (1) MA56116A (https=)
MX (1) MX2021014892A (https=)
TW (1) TW202110892A (https=)
WO (1) WO2020247461A1 (https=)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
SG11202111742QA (en) 2019-04-24 2021-11-29 Sanofi Biotechnology Methods of diagnosis and treatment of rheumatoid arthritis
CA3142710A1 (en) 2019-06-04 2020-12-10 Sanofi Biotechnology Compositions and methods for treating pain in subjects with rheumatoid arthritis
EP4504788A1 (en) * 2022-04-06 2025-02-12 Sanofi Biotechnology Compositions and methods for treating polymyalgia rheumatica by administering an il?6r antagonist

Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2016539125A (ja) * 2013-11-22 2016-12-15 サノフィ・バイオテクノロジー 関節リウマチを治療するための組成物およびこれを使用する方法
JP2019507775A (ja) * 2016-03-07 2019-03-22 サノフィ・バイオテクノロジー 関節リウマチを処置するための組成物及び方法

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