BR112021024445A2 - Composições e métodos para tratamento de dor em indivíduos com artrite reumatoide - Google Patents

Composições e métodos para tratamento de dor em indivíduos com artrite reumatoide

Info

Publication number
BR112021024445A2
BR112021024445A2 BR112021024445A BR112021024445A BR112021024445A2 BR 112021024445 A2 BR112021024445 A2 BR 112021024445A2 BR 112021024445 A BR112021024445 A BR 112021024445A BR 112021024445 A BR112021024445 A BR 112021024445A BR 112021024445 A2 BR112021024445 A2 BR 112021024445A2
Authority
BR
Brazil
Prior art keywords
individuals
rheumatoid arthritis
compositions
methods
pain
Prior art date
Application number
BR112021024445A
Other languages
English (en)
Portuguese (pt)
Inventor
St John Gregory
Stefano Fiore
Susan Boklage
Toshio Kimura
Vivian Bykerk
Wenhui Wei
Original Assignee
Regeneron Pharma
Sanofi Biotechnology
Stefano Fiore
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Regeneron Pharma, Sanofi Biotechnology, Stefano Fiore filed Critical Regeneron Pharma
Publication of BR112021024445A2 publication Critical patent/BR112021024445A2/pt

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies
    • C07K16/18—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/28—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
    • C07K16/2866—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against receptors for cytokines, lymphokines, interferons
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0019—Injectable compositions; Intramuscular, intravenous, arterial, subcutaneous administration; Compositions to be administered through the skin in an invasive manner
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies
    • C07K16/18—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/24—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans against cytokines, lymphokines or interferons
    • C07K16/241—Tumor Necrosis Factors
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/505—Medicinal preparations containing antigens or antibodies comprising antibodies
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/545—Medicinal preparations containing antigens or antibodies characterised by the dose, timing or administration schedule
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/20—Immunoglobulins specific features characterized by taxonomic origin
    • C07K2317/21—Immunoglobulins specific features characterized by taxonomic origin from primates, e.g. man
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/50—Immunoglobulins specific features characterized by immunoglobulin fragments
    • C07K2317/56—Immunoglobulins specific features characterized by immunoglobulin fragments variable (Fv) region, i.e. VH and/or VL
    • C07K2317/565—Complementarity determining region [CDR]
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/70—Immunoglobulins specific features characterized by effect upon binding to a cell or to an antigen
    • C07K2317/76—Antagonist effect on antigen, e.g. neutralization or inhibition of binding

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Immunology (AREA)
  • Genetics & Genomics (AREA)
  • Biophysics (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Biochemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Rheumatology (AREA)
  • Pain & Pain Management (AREA)
  • Dermatology (AREA)
  • Epidemiology (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
BR112021024445A 2019-06-04 2020-06-03 Composições e métodos para tratamento de dor em indivíduos com artrite reumatoide BR112021024445A2 (pt)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
US201962857247P 2019-06-04 2019-06-04
US201962930966P 2019-11-05 2019-11-05
EP20305191 2020-02-27
PCT/US2020/035871 WO2020247461A1 (en) 2019-06-04 2020-06-03 Compositions and methods for treating pain in subj ects with rheumatoid arthritis

Publications (1)

Publication Number Publication Date
BR112021024445A2 true BR112021024445A2 (pt) 2022-02-15

Family

ID=71842803

Family Applications (1)

Application Number Title Priority Date Filing Date
BR112021024445A BR112021024445A2 (pt) 2019-06-04 2020-06-03 Composições e métodos para tratamento de dor em indivíduos com artrite reumatoide

Country Status (14)

Country Link
US (2) US12297279B2 (https=)
EP (1) EP3980459A1 (https=)
JP (2) JP2022534794A (https=)
KR (1) KR20230061198A (https=)
CN (1) CN115667301A (https=)
AU (1) AU2020288561A1 (https=)
BR (1) BR112021024445A2 (https=)
CA (1) CA3142710A1 (https=)
CO (1) CO2021017737A2 (https=)
IL (1) IL288573A (https=)
MA (1) MA56116A (https=)
MX (1) MX2021014892A (https=)
TW (1) TW202110892A (https=)
WO (1) WO2020247461A1 (https=)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
SG11202111742QA (en) 2019-04-24 2021-11-29 Sanofi Biotechnology Methods of diagnosis and treatment of rheumatoid arthritis
CA3142710A1 (en) 2019-06-04 2020-12-10 Sanofi Biotechnology Compositions and methods for treating pain in subjects with rheumatoid arthritis
EP4504788A1 (en) * 2022-04-06 2025-02-12 Sanofi Biotechnology Compositions and methods for treating polymyalgia rheumatica by administering an il?6r antagonist

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MA54861A (fr) 2019-01-31 2021-12-08 Regeneron Pharma Anticorps anti-récepteur de l'il6 pour traiter l'arthrite idiopathique juvénile
SG11202111742QA (en) 2019-04-24 2021-11-29 Sanofi Biotechnology Methods of diagnosis and treatment of rheumatoid arthritis
CA3142710A1 (en) 2019-06-04 2020-12-10 Sanofi Biotechnology Compositions and methods for treating pain in subjects with rheumatoid arthritis
US20220242959A1 (en) 2019-06-12 2022-08-04 Sanofi Biotechnology Modified dosage of subcutaneous tocilizumab for rheumatoid arthritis
US12135885B2 (en) 2020-01-31 2024-11-05 Hewlett Packard Enterprise Development Lp Virtual storage policies for virtual persistent volumes
CA3180369A1 (en) 2020-05-26 2021-12-02 Inka Albrecht Compositions comprising an antibody against interleukin-6 receptor for the treatment of rheumatoid arthritis and methods of using same
US20230192871A1 (en) 2020-05-29 2023-06-22 Sanofi Biotechnology Compositions and methods for treating noninflammatory pain in subjects with rheumatoid arthritis

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US20200399380A1 (en) 2020-12-24
MX2021014892A (es) 2022-06-27
IL288573A (en) 2022-02-01
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KR20230061198A (ko) 2023-05-08
US12297279B2 (en) 2025-05-13
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AU2020288561A1 (en) 2021-12-23
JP2025134086A (ja) 2025-09-16
CO2021017737A2 (es) 2022-05-20
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MA56116A (fr) 2022-04-13
US20250333522A1 (en) 2025-10-30

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