|
JPS6140270A
(ja)
|
1984-08-01 |
1986-02-26 |
Morishita Seiyaku Kk |
ピリダジノン誘導体
|
|
DD286354A5
(de)
|
1989-08-08 |
1991-01-24 |
Karl-Marx-Universitaet Leipzig,De |
Verfahren zur herstellung substituierter 2-carbamoyl-methyl-4-phenyl-1,2,5,6-tetrahydro- und 1,2-dihydro-1-oxo-pyridazine
|
|
ATE180475T1
(de)
|
1990-09-21 |
1999-06-15 |
Rohm & Haas |
Dihydropyridazinone und pyridazinone als fungizide
|
|
US6334997B1
(en)
|
1994-03-25 |
2002-01-01 |
Isotechnika, Inc. |
Method of using deuterated calcium channel blockers
|
|
KR100477070B1
(ko)
|
1994-03-25 |
2006-04-21 |
이소테크니카 인코포레이티드 |
중수소화작용에의한의약품의효능강화법
|
|
IL118631A
(en)
|
1995-06-27 |
2002-05-23 |
Tanabe Seiyaku Co |
History of pyridazinone and processes for their preparation
|
|
DE19629817A1
(de)
|
1996-07-24 |
1998-01-29 |
Hoechst Ag |
Neue Imino-Derivate als Inhibitoren der Knochenresorption und Vitronectinrezeptor-Antagonisten
|
|
CN1471515A
(zh)
|
2000-06-05 |
2004-01-28 |
��̹��ҽҩ��˾ |
作为β2-肾上腺素受体激动剂及PDE-4抑制剂的有效的化合物
|
|
WO2004022540A2
(en)
|
2002-09-06 |
2004-03-18 |
Fujisawa Pharmaceutical Co., Ltd. |
Pyridazinone and pyridone derivatives as adenosine antagonists
|
|
MXPA05009500A
(es)
*
|
2003-03-07 |
2005-10-18 |
Kowa Co |
Derivado de benzofurano.
|
|
US7763617B2
(en)
|
2005-03-07 |
2010-07-27 |
Kyorin Pharmaceutical Co., Ltd. |
Pyrazolopyridine-4-yl pyridazinone derivatives and addition salts thereof, and PDE inhibitors comprising the same derivatives or salts as active ingredient
|
|
WO2007044796A2
(en)
|
2005-10-11 |
2007-04-19 |
Nps Pharmaceuticals, Inc. |
Pyridazinone compounds as calcilytics
|
|
DE102005057924A1
(de)
*
|
2005-12-05 |
2007-06-06 |
Merck Patent Gmbh |
Pyridazinonderivate
|
|
EP2502918B1
(en)
|
2006-07-25 |
2015-03-25 |
Cephalon, Inc. |
Pyridazinone Derivatives
|
|
CA2676173A1
(en)
|
2007-02-16 |
2008-08-28 |
Amgen Inc. |
Nitrogen-containing heterocyclyl ketones and their use as c-met inhibitors
|
|
DE102007025718A1
(de)
*
|
2007-06-01 |
2008-12-04 |
Merck Patent Gmbh |
Pyridazinonderivate
|
|
DE102007025717A1
(de)
*
|
2007-06-01 |
2008-12-11 |
Merck Patent Gmbh |
Arylether-pyridazinonderivate
|
|
DE102007032507A1
(de)
*
|
2007-07-12 |
2009-04-02 |
Merck Patent Gmbh |
Pyridazinonderivate
|
|
GB0715087D0
(en)
|
2007-08-03 |
2007-09-12 |
Summit Corp Plc |
Drug combinations for the treatment of duchenne muscular dystrophy
|
|
DE102007038957A1
(de)
|
2007-08-17 |
2009-02-19 |
Merck Patent Gmbh |
6-Thioxo-pyridazinderivate
|
|
DE102008019907A1
(de)
|
2008-04-21 |
2009-10-22 |
Merck Patent Gmbh |
Pyridazinonderivate
|
|
EP2328586A2
(en)
|
2008-05-20 |
2011-06-08 |
Cephalon, Inc. |
Substituted pyridazinone derivatives as histamine-3 (h3) receptor ligands
|
|
WO2010048149A2
(en)
|
2008-10-20 |
2010-04-29 |
Kalypsys, Inc. |
Heterocyclic modulators of gpr119 for treatment of disease
|
|
AR081626A1
(es)
|
2010-04-23 |
2012-10-10 |
Cytokinetics Inc |
Compuestos amino-piridazinicos, composiciones farmaceuticas que los contienen y uso de los mismos para tratar trastornos musculares cardiacos y esqueleticos
|
|
AR081331A1
(es)
|
2010-04-23 |
2012-08-08 |
Cytokinetics Inc |
Amino- pirimidinas composiciones de las mismas y metodos para el uso de los mismos
|
|
WO2012021707A2
(en)
*
|
2010-08-11 |
2012-02-16 |
The Regents Of The University Of California |
Premature-termination-codons readthrough compounds
|
|
ES2537190T3
(es)
|
2010-09-01 |
2015-06-03 |
Gilead Connecticut, Inc. |
Piridazinonas, procedimiento de preparación y procedimientos de utilización de las mismas
|
|
US8759380B2
(en)
|
2011-04-22 |
2014-06-24 |
Cytokinetics, Inc. |
Certain heterocycles, compositions thereof, and methods for their use
|
|
EP2768826A1
(de)
|
2011-10-17 |
2014-08-27 |
Bayer Intellectual Property GmbH |
Substituierte oxadiazolylpyridinone und - pyridazinone als hif - hemmer
|
|
CN103570730A
(zh)
|
2012-08-01 |
2014-02-12 |
中国科学院上海药物研究所 |
具有桥环结构的稠环哒嗪酮类化合物及其制备方法和用途
|
|
WO2014031928A2
(en)
|
2012-08-24 |
2014-02-27 |
Philip Jones |
Heterocyclic modulators of hif activity for treatment of disease
|
|
US9566310B2
(en)
|
2012-09-10 |
2017-02-14 |
Board Of Regents Of The Nevada System Of Higher Education On Behalf Of The University Of Nevada, Reno |
Methods of treating muscular dystrophy
|
|
WO2014055644A2
(en)
|
2012-10-02 |
2014-04-10 |
New York University |
Pharmaceutical compositions and treatment of genetic diseases associated with nonsense mediated rna decay
|
|
JP2016507496A
(ja)
*
|
2012-12-21 |
2016-03-10 |
ゼニス・エピジェネティクス・コーポレイションZenith Epigenetics Corp. |
ブロモドメイン阻害剤としての新規複素環式化合物
|
|
JP6483624B2
(ja)
*
|
2013-02-07 |
2019-03-13 |
メルク パテント ゲゼルシャフト ミット ベシュレンクテル ハフツングMerck Patent Gesellschaft mit beschraenkter Haftung |
ピリダジノン−アミド誘導体
|
|
EP2968323A4
(en)
|
2013-03-13 |
2016-12-14 |
Flatley Discovery Lab |
PYRIDAZINONE COMPOUNDS AND METHODS FOR THE TREATMENT OF CYSTIC FIBROSIS
|
|
CN105636645A
(zh)
|
2013-04-19 |
2016-06-01 |
爱荷华大学研究基金会 |
在肌萎缩症中的血管紧张素
|
|
CA2987980A1
(en)
|
2015-06-05 |
2016-12-08 |
Ptc Therapeutics, Inc. |
Use of an aminoglycoside for nonsense mutation suppression and the treatment of disease
|
|
EP3307891B8
(en)
|
2015-06-10 |
2019-11-13 |
Association Institut de Myologie |
Combined therapy for duchenne muscular dystrophy
|
|
CN106467495A
(zh)
*
|
2015-08-19 |
2017-03-01 |
中国科学院上海药物研究所 |
哒嗪酮类化合物、其制备方法、药物组合物及用途
|
|
WO2017046117A1
(en)
*
|
2015-09-15 |
2017-03-23 |
Abbvie Inc. |
Substituted isoxazolopyridazinones and isothiazolopyridazinones and methods of use
|
|
EP3532461A1
(en)
|
2016-10-26 |
2019-09-04 |
Proteostasis Therapeutics, Inc. |
N-phenyl-2-(3-phenyl-6-oxo-1,6-dihydropyridazin-1-yl)acetamide derivatives for treating cystic fibrosis
|
|
US20190248779A1
(en)
|
2016-10-26 |
2019-08-15 |
Proteostasis Therapeutics, Inc. |
Compounds, compositions, and methods for increasing cftr activity
|
|
CA3041676A1
(en)
|
2016-10-26 |
2018-05-03 |
Daniel Parks |
Pyridazine derivatives, compositions and methods for modulating cftr
|
|
EP3600322A1
(en)
|
2017-03-28 |
2020-02-05 |
Boehringer Ingelheim International GmbH |
Nintedanib for use in methods for the treatment of muscular dystrophy
|
|
TWI886480B
(zh)
|
2017-04-06 |
2025-06-11 |
美商富曼西公司 |
殺真菌之噁二唑
|
|
US20180303821A1
(en)
|
2017-04-24 |
2018-10-25 |
BraneQuest, Inc. |
Membrane active molecules
|
|
BE1025518B1
(fr)
|
2017-08-30 |
2019-04-03 |
E2 Drives Sa |
Groupe motopropulseur
|
|
WO2019084499A1
(en)
|
2017-10-27 |
2019-05-02 |
Genea Biocells USA (Holdings), Inc. |
INHIBITORS OF DUX4 INDUCTION FOR REGULATION OF MUSCLE FUNCTION
|
|
MX2020012243A
(es)
|
2018-05-17 |
2021-01-29 |
Bolt Threads Inc |
Cepas modificadas con sec para una mejor secrecion de proteinas recombinantes.
|
|
ES3041367T3
(en)
|
2018-06-04 |
2025-11-11 |
Ohio State Innovation Foundation |
Eaat2 activators and methods of using thereof
|
|
EP3828174A4
(en)
|
2018-07-19 |
2022-08-17 |
Sumitomo Pharma Co., Ltd. |
PYRIDAZINONE DERIVATIVE
|
|
CN108947912B
(zh)
|
2018-07-31 |
2021-10-01 |
中国人民解放军总医院 |
一种靶向Neddylation通路的抗肿瘤化合物
|
|
KR102885525B1
(ko)
|
2018-11-06 |
2025-11-13 |
엣지와이즈 테라퓨틱스, 인크. |
피리다지논 화합물 및 이의 용도
|
|
WO2020097258A1
(en)
|
2018-11-06 |
2020-05-14 |
Edgewise Therapeutics, Inc. |
Pyridazinone compounds and uses thereof
|
|
SMT202300355T1
(it)
|
2018-11-06 |
2024-01-10 |
Edgewise Therapeutics Inc |
Composti di piridazinone e loro usi
|
|
EP4473968A3
(en)
|
2020-05-13 |
2025-03-26 |
Edgewise Therapeutics, Inc. |
Pyridazinone compounds and uses thereof
|
|
EP4149465A1
(en)
|
2020-05-13 |
2023-03-22 |
Edgewise Therapeutics, Inc. |
Substituted pyridazinone for use in the treatment of neuromuscular diseases
|
|
EP4149467A1
(en)
|
2020-05-13 |
2023-03-22 |
Edgewise Therapeutics, Inc. |
Substituted pyridazinone for use in the treatment of neuromuscular diseases
|
|
WO2021231630A1
(en)
|
2020-05-13 |
2021-11-18 |
Edgewise Therapeutics, Inc. |
Substituted pyridazinone for use in the treatment of neuromuscular diseases
|
|
WO2021231572A1
(en)
|
2020-05-13 |
2021-11-18 |
Edgewise Therapeutics, Inc. |
Pyridazinone compounds for the treatment of neuromuscular diseases
|
|
JP7694135B2
(ja)
|
2021-05-11 |
2025-06-18 |
株式会社大林組 |
接続構造及び接続方法
|
|
WO2023091606A1
(en)
|
2021-11-17 |
2023-05-25 |
Edgewise Therapeutics, Inc. |
Pyridazinone compounds and uses thereof
|
|
WO2023220180A1
(en)
|
2022-05-11 |
2023-11-16 |
Edgewise Therapeutics, Inc. |
Methods of manufacturing pyridazinone compounds
|
|
JP2025530218A
(ja)
|
2022-09-09 |
2025-09-11 |
エッジワイズ セラピューティクス, インコーポレイテッド |
神経筋の状態の処置のためのピリダジノン組成物
|
|
JP2025040270A
(ja)
*
|
2023-09-11 |
2025-03-24 |
共同印刷株式会社 |
赤外線遮断性生地
|