JP2022043078A5 - - Google Patents
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- Publication number
- JP2022043078A5 JP2022043078A5 JP2021194493A JP2021194493A JP2022043078A5 JP 2022043078 A5 JP2022043078 A5 JP 2022043078A5 JP 2021194493 A JP2021194493 A JP 2021194493A JP 2021194493 A JP2021194493 A JP 2021194493A JP 2022043078 A5 JP2022043078 A5 JP 2022043078A5
- Authority
- JP
- Japan
- Prior art keywords
- pharmaceutically acceptable
- acceptable salt
- compound
- following compounds
- dmap
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
- 150000001875 compounds Chemical class 0.000 claims 6
- 150000003839 salts Chemical class 0.000 claims 5
- VHYFNPMBLIVWCW-UHFFFAOYSA-N 4-Dimethylaminopyridine Chemical compound CN(C)C1=CC=NC=C1 VHYFNPMBLIVWCW-UHFFFAOYSA-N 0.000 claims 2
- 229960000549 4-dimethylaminophenol Drugs 0.000 claims 1
- 239000002904 solvent Substances 0.000 claims 1
- ITMCEJHCFYSIIV-UHFFFAOYSA-N triflic acid Chemical compound OS(=O)(=O)C(F)(F)F ITMCEJHCFYSIIV-UHFFFAOYSA-N 0.000 claims 1
Applications Claiming Priority (8)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| EP15174936 | 2015-07-02 | ||
| EP15174936.3 | 2015-07-02 | ||
| EP16174718.3 | 2016-06-16 | ||
| EP16174718 | 2016-06-16 | ||
| EP16174713.4 | 2016-06-16 | ||
| EP16174713 | 2016-06-16 | ||
| JP2017567655A JP7099824B2 (ja) | 2015-07-02 | 2016-07-01 | 抗菌化合物 |
| PCT/EP2016/065499 WO2017001660A1 (en) | 2015-07-02 | 2016-07-01 | Antibacterial compounds |
Related Parent Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2017567655A Division JP7099824B2 (ja) | 2015-07-02 | 2016-07-01 | 抗菌化合物 |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2022043078A JP2022043078A (ja) | 2022-03-15 |
| JP2022043078A5 true JP2022043078A5 (enExample) | 2022-11-09 |
| JP7516338B2 JP7516338B2 (ja) | 2024-07-16 |
Family
ID=56289523
Family Applications (3)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2017567655A Active JP7099824B2 (ja) | 2015-07-02 | 2016-07-01 | 抗菌化合物 |
| JP2017567289A Pending JP2018519302A (ja) | 2015-07-02 | 2016-07-01 | 抗菌化合物 |
| JP2021194493A Active JP7516338B2 (ja) | 2015-07-02 | 2021-11-30 | 抗菌化合物 |
Family Applications Before (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2017567655A Active JP7099824B2 (ja) | 2015-07-02 | 2016-07-01 | 抗菌化合物 |
| JP2017567289A Pending JP2018519302A (ja) | 2015-07-02 | 2016-07-01 | 抗菌化合物 |
Country Status (29)
| Country | Link |
|---|---|
| US (6) | US20180155341A1 (enExample) |
| EP (3) | EP4074378A1 (enExample) |
| JP (3) | JP7099824B2 (enExample) |
| KR (2) | KR102710552B1 (enExample) |
| CN (3) | CN113980015A (enExample) |
| AU (3) | AU2016287478B2 (enExample) |
| BR (1) | BR112017028318B1 (enExample) |
| CA (1) | CA2986331A1 (enExample) |
| CL (1) | CL2017003404A1 (enExample) |
| CO (1) | CO2017013408A2 (enExample) |
| DK (1) | DK3316969T3 (enExample) |
| EA (2) | EA201890204A1 (enExample) |
| ES (1) | ES2914681T3 (enExample) |
| HK (1) | HK1249468A1 (enExample) |
| HR (1) | HRP20220339T1 (enExample) |
| IL (2) | IL256379A (enExample) |
| LT (1) | LT3316969T (enExample) |
| MA (1) | MA42293A (enExample) |
| MD (1) | MD3316969T2 (enExample) |
| MX (2) | MX2017016789A (enExample) |
| PE (1) | PE20180520A1 (enExample) |
| PH (2) | PH12017502297A1 (enExample) |
| PL (1) | PL3316969T3 (enExample) |
| RS (1) | RS63201B1 (enExample) |
| SI (1) | SI3316969T1 (enExample) |
| SM (1) | SMT202200220T1 (enExample) |
| UA (1) | UA125171C2 (enExample) |
| WO (2) | WO2017001661A1 (enExample) |
| ZA (1) | ZA201708692B (enExample) |
Families Citing this family (47)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| KR102043337B1 (ko) | 2014-08-28 | 2019-11-11 | 아셰뉴론 에스아 | 글리코시다제 저해제 |
| AU2016287478B2 (en) * | 2015-07-02 | 2021-10-21 | Janssen Sciences Ireland Uc | Antibacterial compounds |
| SG10201913880XA (en) | 2015-07-02 | 2020-03-30 | Hoffmann La Roche | Bicyclic lactams and methods of use thereof |
| IL257743B (en) | 2015-09-17 | 2022-08-01 | Marvin J Miller | Benzyl amine-containing heterocyclic compounds and compositions useful against mycobacterial infection |
| US11261183B2 (en) | 2016-02-25 | 2022-03-01 | Asceneuron Sa | Sulfoximine glycosidase inhibitors |
| ES2879351T3 (es) | 2016-02-25 | 2021-11-22 | Asceneuron Sa | Sales de derivados de piperazina obtenidas por adición de ácidos |
| MA43680A (fr) | 2016-02-25 | 2018-11-28 | Asceneuron Sa | Inhibiteurs de glycosidases |
| JP2019510006A (ja) | 2016-02-25 | 2019-04-11 | エースニューロン・ソシエテ・アノニム | グリコシダーゼ阻害剤 |
| BR112018068703B1 (pt) | 2016-03-16 | 2024-02-06 | Kura Oncology, Inc. | Inibidores substituídos de menin-mll e métodos de uso |
| JP2019518046A (ja) | 2016-06-16 | 2019-06-27 | ヤンセン・サイエンシズ・アイルランド・アンリミテッド・カンパニー | 抗菌薬としての複素環式化合物 |
| WO2018073193A1 (en) | 2016-10-17 | 2018-04-26 | F. Hoffmann-La Roche Ag | Bicyclic pyridone lactams and methods of use thereof |
| US11072607B2 (en) | 2016-12-16 | 2021-07-27 | Genentech, Inc. | Inhibitors of RIP1 kinase and methods of use thereof |
| WO2018141984A1 (en) | 2017-02-06 | 2018-08-09 | Janssen Pharmaceutica Nv | Oga inhibitor compounds |
| US11224596B2 (en) | 2017-03-01 | 2022-01-18 | Janssen Sciences Ireland Unlimited Company | PZA and cytochrome bc1 inhibitor combination treatment |
| US11213525B2 (en) | 2017-08-24 | 2022-01-04 | Asceneuron Sa | Linear glycosidase inhibitors |
| TW201920170A (zh) | 2017-09-20 | 2019-06-01 | 美商庫拉腫瘤技術股份有限公司 | 經取代之menin-mll 抑制劑及使用方法 |
| CA3079188A1 (en) | 2017-10-17 | 2019-04-25 | Vanderbilt University | Antagonists of the muscarinic acetylcholine receptor m4 |
| US11325896B2 (en) | 2017-12-20 | 2022-05-10 | Vanderbilt University | Antagonists of the muscarinic acetylcholine receptor M4 |
| RU2680972C1 (ru) * | 2018-02-13 | 2019-03-01 | Федеральное государственное бюджетное научное учреждение "Центральный научно-исследовательский институт туберкулеза" | Способ определения длительности химиотерапии туберкулеза органов дыхания с множественной и широкой лекарственной устойчивостью МБТ у детей и подростков |
| WO2019175737A1 (en) * | 2018-03-12 | 2019-09-19 | University Of Notre Dame Du Lac | Deuterated imidazopyridines |
| EP3781571B1 (en) | 2018-04-20 | 2024-01-17 | F. Hoffmann-La Roche AG | N-[4-oxo-2,3-dihydro-pyrido[3,2-b][1,4]oxazepin-3-yl]-5,6-dihydro-4h-pyrrolo[1,2-b]pyrazole-2-carboxamide derivatives and related compounds as rip1 kinase inhibitors for treating e.g. irritable bowel syndrome (ibs) |
| WO2020039027A1 (en) | 2018-08-22 | 2020-02-27 | Asceneuron S. A. | Pyrrolidine glycosidase inhibitors |
| EA202190275A1 (ru) | 2018-08-22 | 2021-08-02 | Асенейрон С. А. | Сукцинатные и фумаратные кислотно-аддитивные соли производных пиперазина, пригодные в качестве ингибиторов гликозидазы |
| US11731972B2 (en) | 2018-08-22 | 2023-08-22 | Asceneuron Sa | Spiro compounds as glycosidase inhibitors |
| WO2020039028A1 (en) | 2018-08-22 | 2020-02-27 | Asceneuron S. A. | Tetrahydro-benzoazepine glycosidase inhibitors |
| CN109503631A (zh) * | 2018-12-29 | 2019-03-22 | 中国医学科学院医药生物技术研究所 | 含有二氮杂螺环片段的咪唑并[1,2-a]吡啶-3-酰胺类化合物及其制备方法和应用 |
| US20220235047A1 (en) * | 2019-05-28 | 2022-07-28 | Shionogi & Co., Ltd. | A MEDICAMENT FOR TREATING MYCOBACTERIAL INFECTION CHARACTERIZED BY COMBINING A CYTOCHROME bc1 INHIBITOR WITH CLARITHROMYCIN OR AZITHROMYCIN AND CLOFAZIMINE |
| KR102076958B1 (ko) | 2019-06-24 | 2020-02-13 | 엘티소재주식회사 | 헤테로고리 화합물 및 이를 이용한 유기 발광 소자 |
| TWI861208B (zh) | 2019-09-10 | 2024-11-11 | 日商鹽野義製藥股份有限公司 | 對分枝桿菌感染有用之含苄胺的 5,6-雜芳族化合物 |
| US20220340564A1 (en) | 2019-09-13 | 2022-10-27 | Janssen Sciences Ireland Unlimited Company | Antibacterial compounds |
| US20220372033A1 (en) | 2019-09-30 | 2022-11-24 | Janssen Sciences Ireland Unlimited Company | Antibacterial compounds |
| US20220389008A1 (en) | 2019-09-30 | 2022-12-08 | Janssen Sciences Ireland Unlimited Company | 4-quinolinone antibacterial compounds |
| PE20221725A1 (es) | 2019-12-27 | 2022-11-04 | Tecnimede Sociedade Tecnico Medicinal Sa | Nuevos compuestos farmaceuticos |
| KR20230157400A (ko) | 2021-03-16 | 2023-11-16 | 얀센 사이언시즈 아일랜드 언리미티드 컴퍼니 | 항박테리아성 화합물 |
| AU2022240967A1 (en) | 2021-03-17 | 2023-11-02 | Janssen Sciences Ireland Unlimited Company | Antibacterial compounds |
| KR20230157445A (ko) | 2021-03-17 | 2023-11-16 | 얀센 사이언시즈 아일랜드 언리미티드 컴퍼니 | 항박테리아성 화합물 |
| WO2022214519A1 (en) | 2021-04-07 | 2022-10-13 | Janssen Sciences Ireland Unlimited Company | Antibacterial compounds |
| WO2022214520A1 (en) | 2021-04-07 | 2022-10-13 | Janssen Sciences Ireland Unlimited Company | Antibacterial compounds |
| MX2024000111A (es) | 2021-06-29 | 2024-01-19 | Tecnimede Sociedade Tecnico Medicinal Sa | Compuestos heterociclicos para el tratamiento de tuberculosis. |
| US20250034171A1 (en) | 2021-10-28 | 2025-01-30 | Janssen Sciences Ireland Unlimited Company | Imidazopyridine amides and related compounds for use in the treatment of bacterial infections |
| CN114957954B (zh) * | 2022-05-16 | 2024-08-20 | 万华化学集团股份有限公司 | 一种用于光学透镜的热塑性树脂组合物及其制备方法和应用 |
| CA3249092A1 (en) * | 2022-06-15 | 2023-12-21 | C4 Therapeutics, Inc. | COMPOUNDS FOR THE TARGETED DEGRADATION OF SMARCA2 |
| TW202409040A (zh) | 2022-07-19 | 2024-03-01 | 大陸商西藏海思科製藥有限公司 | 作為激酶抑制劑的喹唑啉酮衍生物的製備及其用途 |
| WO2024089170A1 (en) | 2022-10-27 | 2024-05-02 | Janssen Sciences Ireland Unlimited Company | Antibacterial compounds |
| WO2024223859A1 (en) | 2023-04-26 | 2024-10-31 | Janssen Pharmaceutica Nv | Antibacterial compounds |
| WO2025017047A1 (en) | 2023-07-18 | 2025-01-23 | Janssen Pharmaceutica Nv | Combination products of at least three antibiotics comprising bedaquiline, pretomanid or delamanid, and a cytochrome bc1 inhibitor, and their use in the treatment of mycobacterial infections |
| WO2025129116A1 (en) * | 2023-12-14 | 2025-06-19 | C4 Therapeutics, Inc. | Compounds for the targeted degradation of smarca2 |
Family Cites Families (29)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JPH10508844A (ja) | 1994-11-15 | 1998-09-02 | ファルマシア・アンド・アップジョン・カンパニー | 二環式オキサジンおよびチアジンオキサゾリジノン抗菌剤 |
| PT828741E (pt) | 1995-05-11 | 2002-02-28 | Upjohn Co | Oxazolidinonas de diazinilo espirociclico e biciclico e de carbazinilo |
| DK2301544T3 (da) | 2002-07-25 | 2013-01-02 | Janssen Pharmaceutica Nv | Quinolinderivater som mellemprodukter til mykobakterielle inhibitorer |
| AR042956A1 (es) | 2003-01-31 | 2005-07-13 | Vertex Pharma | Inhibidores de girasa y usos de los mismos |
| MA27360A1 (fr) | 2004-11-23 | 2005-06-01 | Brahim Bennani | Synthese et application des spiro-isoxazolines comme agents anti-tuberculeux |
| CA2672960A1 (en) | 2006-12-20 | 2008-07-10 | Schering Corporation | Novel jnk inhibitors |
| CL2008001631A1 (es) * | 2007-06-06 | 2009-01-02 | Smithkline Beecham Corp | Compuestos derivados de heterociclos sustituidos, con la presencia de un grupo fenoxi, inhibidores de transcriptasa inversa; composicion farmaceutica; y uso en el tratamiento de infecciones virales por vih. |
| TWI498115B (zh) | 2007-12-27 | 2015-09-01 | Daiichi Sankyo Co Ltd | 咪唑羰基化合物 |
| US7666864B2 (en) | 2008-03-26 | 2010-02-23 | Global Alliance For Tb Drug Development | Bicyclic nitroimidazole-substituted phenyl oxazolidinones |
| JP2012503206A (ja) | 2008-09-22 | 2012-02-02 | オレゴン ヘルス アンド サイエンス ユニバーシティ | Ｍｙｃｏｂａｃｔｅｒｉｕｍｔｕｂｅｒｃｕｌｏｓｉｓ感染を検出するための方法 |
| EP2379513A1 (en) | 2008-12-30 | 2011-10-26 | Millennium Pharmaceuticals, Inc. | Heteroaryl compounds useful as raf kinase inhibitors |
| IN2012DN04917A (enExample) | 2009-11-05 | 2015-09-25 | Univ Notre Dame Du Lac | |
| AU2011229423B2 (en) * | 2010-03-18 | 2015-12-10 | Institut National De La Sante Et De La Recherche Medicale (Inserm) | Anti-infective compounds |
| KR20140093610A (ko) | 2011-04-21 | 2014-07-28 | 재단법인 한국파스퇴르연구소 | 소염 화합물 |
| BR112014004319A2 (pt) | 2011-09-01 | 2017-03-14 | Irm Llc | compostos e composições como inibidores de c-kit cinase |
| US9199981B2 (en) | 2011-09-01 | 2015-12-01 | Novartis Ag | Compounds and compositions as C-kit kinase inhibitors |
| BR112014004560A2 (pt) | 2011-09-01 | 2017-04-04 | Irm Llc | compostos e composições como inibidores de c-kit quinase |
| US9822129B2 (en) * | 2012-03-02 | 2017-11-21 | Genentech, Inc. | Amido spirocyclic amide and sulfonamide derivatives |
| KR101918469B1 (ko) | 2012-06-04 | 2018-11-15 | 한국화학연구원 | 바이사이클릭 니트로이미다졸 유도체 또는 이들의 광학이성질체, 이의 약학적으로 허용가능한 염, 이의 제조방법 및 이를 유효성분으로 함유하는 약제학적 조성물 |
| RU2696278C2 (ru) * | 2012-07-18 | 2019-08-01 | Юниверсити Оф Нотр Дам Дю Лак | 5,5-гетероароматические противоинфекционные соединения |
| KR101650716B1 (ko) | 2012-11-22 | 2016-08-24 | 한국화학연구원 | 바이시클릭니트로이미다졸 유도체, 이의 제조방법 및 이를 유효성분으로 함유하는 결핵의 예방 또는 치료용 약학적 조성물 |
| CN109575018A (zh) * | 2013-08-02 | 2019-04-05 | 韩国巴斯德研究所 | 一种抗感染化合物 |
| KR101564425B1 (ko) | 2013-11-26 | 2015-10-30 | 한국화학연구원 | 신규한 바이사이클릭 니트로이미다졸 카바메이트 화합물, 이를 제조하는 방법 및 이를 유효성분으로 함유하는 결핵 질환의 예방 또는 치료용 약제학적 조성물 |
| CN105524058B (zh) * | 2014-10-21 | 2018-03-27 | 广州艾格生物科技有限公司 | 吡唑并[1,5‑a]吡啶类化合物及其应用 |
| US10080749B2 (en) | 2014-11-03 | 2018-09-25 | The Regents Of The University Of California | Multi-drug therapies for tuberculosis treatment |
| AU2016287478B2 (en) * | 2015-07-02 | 2021-10-21 | Janssen Sciences Ireland Uc | Antibacterial compounds |
| JP2019518046A (ja) | 2016-06-16 | 2019-06-27 | ヤンセン・サイエンシズ・アイルランド・アンリミテッド・カンパニー | 抗菌薬としての複素環式化合物 |
| EA201990044A1 (ru) | 2016-06-16 | 2019-05-31 | Янссен Сайенсиз Айрлэнд Анлимитед Компани | Гетероциклические соединения в качестве антибактериальных средств |
| US11224596B2 (en) | 2017-03-01 | 2022-01-18 | Janssen Sciences Ireland Unlimited Company | PZA and cytochrome bc1 inhibitor combination treatment |
-
2016
- 2016-07-01 AU AU2016287478A patent/AU2016287478B2/en not_active Expired - Fee Related
- 2016-07-01 UA UAA201800904A patent/UA125171C2/uk unknown
- 2016-07-01 JP JP2017567655A patent/JP7099824B2/ja active Active
- 2016-07-01 US US15/736,524 patent/US20180155341A1/en not_active Abandoned
- 2016-07-01 ES ES16734637T patent/ES2914681T3/es active Active
- 2016-07-01 MX MX2017016789A patent/MX2017016789A/es unknown
- 2016-07-01 CN CN202111173668.2A patent/CN113980015A/zh active Pending
- 2016-07-01 WO PCT/EP2016/065503 patent/WO2017001661A1/en not_active Ceased
- 2016-07-01 BR BR112017028318-2A patent/BR112017028318B1/pt active IP Right Grant
- 2016-07-01 CN CN201680038659.3A patent/CN107708809A/zh active Pending
- 2016-07-01 SM SM20220220T patent/SMT202200220T1/it unknown
- 2016-07-01 CA CA2986331A patent/CA2986331A1/en not_active Abandoned
- 2016-07-01 DK DK16734637.8T patent/DK3316969T3/da active
- 2016-07-01 AU AU2016287477A patent/AU2016287477B2/en active Active
- 2016-07-01 LT LTEPPCT/EP2016/065499T patent/LT3316969T/lt unknown
- 2016-07-01 KR KR1020187001923A patent/KR102710552B1/ko active Active
- 2016-07-01 PL PL16734637T patent/PL3316969T3/pl unknown
- 2016-07-01 EP EP22158386.7A patent/EP4074378A1/en not_active Withdrawn
- 2016-07-01 PE PE2017002738A patent/PE20180520A1/es unknown
- 2016-07-01 US US15/736,375 patent/US10364232B2/en active Active
- 2016-07-01 HK HK18109081.1A patent/HK1249468A1/zh unknown
- 2016-07-01 MX MX2017016788A patent/MX386598B/es unknown
- 2016-07-01 SI SI201631501T patent/SI3316969T1/sl unknown
- 2016-07-01 HR HRP20220339TT patent/HRP20220339T1/hr unknown
- 2016-07-01 WO PCT/EP2016/065499 patent/WO2017001660A1/en not_active Ceased
- 2016-07-01 EA EA201890204A patent/EA201890204A1/ru unknown
- 2016-07-01 EP EP16734637.8A patent/EP3316969B1/en active Active
- 2016-07-01 MD MDE20180478T patent/MD3316969T2/ro unknown
- 2016-07-01 CN CN201680038644.7A patent/CN108235704B/zh active Active
- 2016-07-01 KR KR1020187002072A patent/KR20180022833A/ko not_active Ceased
- 2016-07-01 RS RS20220464A patent/RS63201B1/sr unknown
- 2016-07-01 MA MA042293A patent/MA42293A/fr unknown
- 2016-07-01 EP EP16733105.7A patent/EP3316968A1/en not_active Ceased
- 2016-07-01 EA EA201890201A patent/EA201890201A1/ru unknown
- 2016-07-01 JP JP2017567289A patent/JP2018519302A/ja active Pending
-
2017
- 2017-12-13 PH PH12017502297A patent/PH12017502297A1/en unknown
- 2017-12-13 PH PH12017502298A patent/PH12017502298B1/en unknown
- 2017-12-18 IL IL256379A patent/IL256379A/en unknown
- 2017-12-18 IL IL256391A patent/IL256391B/en active IP Right Grant
- 2017-12-20 ZA ZA2017/08692A patent/ZA201708692B/en unknown
- 2017-12-26 CO CONC2017/0013408A patent/CO2017013408A2/es unknown
- 2017-12-27 CL CL2017003404A patent/CL2017003404A1/es unknown
-
2019
- 2019-07-02 US US16/460,334 patent/US20190330189A1/en not_active Abandoned
-
2020
- 2020-04-14 US US16/848,337 patent/US11180472B2/en active Active
-
2021
- 2021-09-17 US US17/477,970 patent/US11866419B2/en active Active
- 2021-11-30 JP JP2021194493A patent/JP7516338B2/ja active Active
-
2022
- 2022-01-20 AU AU2022200385A patent/AU2022200385B2/en active Active
-
2023
- 2023-11-29 US US18/523,171 patent/US20240132470A1/en not_active Abandoned
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