JP2021514665A5 - - Google Patents
Info
- Publication number
- JP2021514665A5 JP2021514665A5 JP2020547001A JP2020547001A JP2021514665A5 JP 2021514665 A5 JP2021514665 A5 JP 2021514665A5 JP 2020547001 A JP2020547001 A JP 2020547001A JP 2020547001 A JP2020547001 A JP 2020547001A JP 2021514665 A5 JP2021514665 A5 JP 2021514665A5
- Authority
- JP
- Japan
- Prior art keywords
- item
- cells
- enucleated
- polypeptide
- exogenous
- Prior art date
Links
Applications Claiming Priority (13)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201862640530P | 2018-03-08 | 2018-03-08 | |
| US62/640,530 | 2018-03-08 | ||
| US201862660657P | 2018-04-20 | 2018-04-20 | |
| US62/660,657 | 2018-04-20 | ||
| US201862680490P | 2018-06-04 | 2018-06-04 | |
| US62/680,490 | 2018-06-04 | ||
| US201862692487P | 2018-06-29 | 2018-06-29 | |
| US62/692,487 | 2018-06-29 | ||
| US201862732050P | 2018-09-17 | 2018-09-17 | |
| US62/732,050 | 2018-09-17 | ||
| US201862757717P | 2018-11-08 | 2018-11-08 | |
| US62/757,717 | 2018-11-08 | ||
| PCT/US2019/021490 WO2019173798A1 (en) | 2018-03-08 | 2019-03-08 | Therapeutic cell systems and methods for treating cancer and infectious diseases |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2021514665A JP2021514665A (ja) | 2021-06-17 |
| JP2021514665A5 true JP2021514665A5 (https=) | 2022-03-16 |
| JPWO2019173798A5 JPWO2019173798A5 (https=) | 2022-03-16 |
Family
ID=65904565
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2020547001A Pending JP2021514665A (ja) | 2018-03-08 | 2019-03-08 | がんおよび感染症を処置するための治療用細胞系および方法 |
Country Status (12)
| Country | Link |
|---|---|
| US (2) | US11141433B2 (https=) |
| EP (1) | EP3762422A1 (https=) |
| JP (1) | JP2021514665A (https=) |
| KR (1) | KR20200140279A (https=) |
| CN (1) | CN112105723A (https=) |
| AU (1) | AU2019232012A1 (https=) |
| CA (1) | CA3093387A1 (https=) |
| IL (1) | IL277159A (https=) |
| MX (1) | MX2020009359A (https=) |
| RU (1) | RU2020132924A (https=) |
| SG (1) | SG11202008261WA (https=) |
| WO (1) | WO2019173798A1 (https=) |
Families Citing this family (26)
| Publication number | Priority date | Publication date | Assignee | Title |
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| US11629340B2 (en) | 2017-03-03 | 2023-04-18 | Obsidian Therapeutics, Inc. | DHFR tunable protein regulation |
| AU2018316166A1 (en) | 2017-08-07 | 2020-02-06 | The Regents Of The University Of California | Platform for generating safe cell therapeutics |
| EP3762422A1 (en) | 2018-03-08 | 2021-01-13 | Rubius Therapeutics, Inc. | Therapeutic cell systems and methods for treating cancer and infectious diseases |
| JP2022513705A (ja) * | 2018-12-03 | 2022-02-09 | ルビウス セラピューティクス， インコーポレイテッド | Ｈｌａ－ｅおよびｈｌａ－ｇ分子を含む人工抗原提示細胞、ならびに使用の方法 |
| JP2022530130A (ja) | 2019-04-26 | 2022-06-27 | ルビウス セラピューティクス， インコーポレイテッド | 除核赤血球細胞を含む緩衝組成物 |
| US20220241375A1 (en) | 2019-05-20 | 2022-08-04 | Cytune Pharma | Il-2/il-15r beta gamma agonist dosing regimens for treating cancer or infectious diseases |
| CN110777115B (zh) * | 2019-11-21 | 2020-08-21 | 北京启辰生生物科技有限公司 | 用于促进辅助T细胞产生TNF-α细胞因子的工程化DC细胞及方法 |
| CN115397395A (zh) * | 2020-02-07 | 2022-11-25 | 加利福尼亚大学董事会 | 生物工程去核细胞的方法和用途 |
| CN115151636A (zh) * | 2020-02-10 | 2022-10-04 | 鲁比厄斯治疗法股份有限公司 | 包含hla-g多肽的经工程改造的红系细胞及其使用方法 |
| CN111849896B (zh) * | 2020-07-31 | 2022-07-01 | 广东昭泰体内生物医药科技有限公司 | 一种car-nk细胞培养基及其应用 |
| EP4232069A1 (en) | 2020-10-26 | 2023-08-30 | Cytune Pharma | Il-2/il-15rbetagamma agonist for treating squamous cell carcinoma |
| MX2023004880A (es) | 2020-10-26 | 2023-05-11 | Cytune Pharma | AGONISTA DE IL-2/IL-15RßY PARA EL TRATAMIENTO DE CÁNCER DE PIEL QUE NO ES MELANOMA. |
| TW202241471A (zh) | 2021-01-08 | 2022-11-01 | 美商盧比亞斯治療公司 | 提高個體中NKp30陽性淋巴球的方法及其用途 |
| TW202241470A (zh) | 2021-01-08 | 2022-11-01 | 美商盧比亞斯治療公司 | 治療人類個體腫瘤之方法 |
| WO2022197548A1 (en) | 2021-03-14 | 2022-09-22 | Rubius Therapeutics, Inc. | Methods of increasing nkg2d-positive lymphocytes in a subject and uses thereof |
| KR102829749B1 (ko) * | 2021-06-01 | 2025-07-07 | 주식회사 박셀바이오 | 배양보조세포를 포함하는 자연살해세포 증식용 조성물 |
| TW202317179A (zh) | 2021-06-03 | 2023-05-01 | 美商盧比亞斯治療公司 | 在個體中治療ｈｐｖ１６－陽性或ｈｐｖ１６－相關的癌症之方法 |
| CN115595310A (zh) * | 2021-07-08 | 2023-01-13 | 中国医学科学院血液病医院（中国医学科学院血液学研究所）（Cn） | Nk细胞的滋养细胞、其制备方法和应用 |
| CN113599395B (zh) * | 2021-09-22 | 2022-08-12 | 郑州源创吉因实业有限公司 | 含有nk细胞的治疗癌症的药物组合物 |
| CN114113639B (zh) * | 2022-01-29 | 2022-04-19 | 北京大有天弘科技有限公司 | 一种血型抗体检测方法及其应用 |
| WO2023250484A2 (en) * | 2022-06-24 | 2023-12-28 | Emory University | Recombinant interleukin-37, chimeric antigen receptors, nucleic acids, and vectors encoding the same and uses in cancer therapies |
| KR20250139902A (ko) * | 2022-12-28 | 2025-09-23 | 사이토누스 테라퓨틱스, 인크. | 암 치료용 조성물 및 방법 |
| EP4694916A1 (en) | 2023-04-14 | 2026-02-18 | SOTIO Biotech Inc. | Engineered immune cells for treating cancer in combination with il-2/il-15 receptor ?? agonists |
| CN116789795A (zh) * | 2023-06-21 | 2023-09-22 | 广州奥科生物医学科技有限公司 | 一种将外源过表达蛋白锚定细胞膜上的多肽及应用 |
| CN117304343B (zh) * | 2023-10-11 | 2024-05-07 | 北京景达生物科技有限公司 | Gpc3靶向的car-nk细胞的制备及其应用 |
| WO2025221669A1 (en) * | 2024-04-18 | 2025-10-23 | Promab Biotechnologies, Inc. | Fusion protein comprising il-12 and gm-csf |
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| US4327710A (en) | 1980-06-18 | 1982-05-04 | The United States Of America As Represented By The Secretary Of Agriculture | Process for encapsulating additives in resealed erythrocytes for disseminating chemicals via the circulatory system |
| US4935223A (en) | 1988-08-04 | 1990-06-19 | Board Of Regents, The University Of Texas System | Labeled cells for use in imaging |
| DE69127615T2 (de) | 1991-06-14 | 1998-03-19 | Europ Communities | Transformierte Erythrozyten, Verfahren zu deren Herstellung, und ihre Verwendung in pharmazeutischen Zusammensetzungen |
| EP0882448B1 (en) | 1997-05-05 | 2005-01-12 | DIDECO S.r.l. | Method of encapsulating biologically active agents within erythrocytes and apparatus therefor |
| US6495351B2 (en) | 2000-02-08 | 2002-12-17 | Gendel Limited | Loading system and method for using the same |
| DE10335833A1 (de) * | 2003-08-05 | 2005-03-03 | Curevac Gmbh | Transfektion von Blutzellen mit mRNA zur Immunstimulation und Gentherapie |
| US7288638B2 (en) | 2003-10-10 | 2007-10-30 | Bristol-Myers Squibb Company | Fully human antibodies against human 4-1BB |
| EP2366787B1 (en) * | 2006-01-13 | 2019-12-11 | The Government Of The U.S.A, As Represented By The Secretary, Dept. Of Health And Human Services | Codon optimized IL-15 and IL-15R-Alpha genes for expression in mammalian cells |
| US20070243137A1 (en) | 2006-04-18 | 2007-10-18 | Nanoprobes, Inc. | Cell and sub-cell methods for imaging and therapy |
| NZ582330A (en) * | 2007-06-27 | 2012-05-25 | Marinepolymer Tech Inc | COMPLEXES OF IL-15 AND IL-15Ra (RECEPTOR ALPHA) AND USES THEREOF |
| FR2919804B1 (fr) * | 2007-08-08 | 2010-08-27 | Erytech Pharma | Composition et vaccin therapeutique anti-tumoral |
| US20100040546A1 (en) | 2008-08-13 | 2010-02-18 | Searete Llc, A Limited Liability Corporation Of The State Of Delaware | Biological targeting compositions and methods of using the same |
| PT2614082T (pt) | 2010-09-09 | 2018-12-03 | Pfizer | Moléculas de ligação a 4-1bb |
| WO2012129109A2 (en) | 2011-03-18 | 2012-09-27 | New York Blood Center, Inc. | Megakaryocyte and platelet production from stem cells |
| EP3546484B1 (en) | 2013-05-10 | 2021-09-08 | Whitehead Institute for Biomedical Research | In vitro production of red blood cells with sortaggable proteins |
| US10260038B2 (en) | 2013-05-10 | 2019-04-16 | Whitehead Institute For Biomedical Research | Protein modification of living cells using sortase |
| AU2014348683B2 (en) | 2013-11-18 | 2020-11-05 | Rubius Therapeutics, Inc. | Synthetic membrane-receiver complexes |
| ES2865825T3 (es) | 2014-04-01 | 2021-10-18 | Rubius Therapeutics Inc | Procedimientos y composiciones para inmunomodulación |
| KR20160145802A (ko) * | 2014-04-23 | 2016-12-20 | 보드 오브 리전츠, 더 유니버시티 오브 텍사스 시스템 | 요법에 사용하기 위한 키메라 항원 수용체 (car) 및 이의 제조 방법 |
| SG10201913163PA (en) * | 2015-12-18 | 2020-03-30 | Oncosec Medical Inc | Plasmid constructs for heterologous protein expression and methods of use |
| AU2017207736A1 (en) * | 2016-01-11 | 2018-07-12 | Rubius Therapeutics, Inc. | Compositions and methods related to multimodal therapeutic cell systems for immune indications |
| KR20180096789A (ko) | 2016-01-11 | 2018-08-29 | 인히브릭스, 인크. | 다가 및 다중특이적 41bb-결합 융합 단백질 |
| BR112019000195A2 (pt) | 2016-07-07 | 2019-04-24 | Rubius Therapeutics, Inc. | composições e métodos relacionados a sistemas celulares terapêuticos que expressam rna exógeno |
| CN106755107B (zh) * | 2016-11-22 | 2019-10-01 | 上海健信生物医药科技有限公司 | 一种car新分子及其在肿瘤治疗中的应用 |
| KR20190091497A (ko) * | 2016-12-02 | 2019-08-06 | 루비우스 테라퓨틱스, 아이엔씨. | 고형 종양으로의 침투를 위한 세포 시스템과 관련된 조성물 및 방법 |
| CN110520522A (zh) | 2017-02-17 | 2019-11-29 | 鲁比厄斯治疗法股份有限公司 | 功能化红系细胞 |
| CN111511762B (zh) | 2017-08-21 | 2025-05-06 | 天演药业公司 | 抗cd137分子及其用途 |
| EP3762422A1 (en) | 2018-03-08 | 2021-01-13 | Rubius Therapeutics, Inc. | Therapeutic cell systems and methods for treating cancer and infectious diseases |
-
2019
- 2019-03-08 EP EP19713277.2A patent/EP3762422A1/en not_active Withdrawn
- 2019-03-08 WO PCT/US2019/021490 patent/WO2019173798A1/en not_active Ceased
- 2019-03-08 US US16/297,540 patent/US11141433B2/en not_active Expired - Fee Related
- 2019-03-08 MX MX2020009359A patent/MX2020009359A/es unknown
- 2019-03-08 JP JP2020547001A patent/JP2021514665A/ja active Pending
- 2019-03-08 KR KR1020207029027A patent/KR20200140279A/ko not_active Withdrawn
- 2019-03-08 CN CN201980030291.XA patent/CN112105723A/zh active Pending
- 2019-03-08 AU AU2019232012A patent/AU2019232012A1/en not_active Withdrawn
- 2019-03-08 SG SG11202008261WA patent/SG11202008261WA/en unknown
- 2019-03-08 RU RU2020132924A patent/RU2020132924A/ru unknown
- 2019-03-08 CA CA3093387A patent/CA3093387A1/en active Pending
-
2020
- 2020-09-06 IL IL277159A patent/IL277159A/en unknown
-
2021
- 2021-09-27 US US17/486,537 patent/US20220088076A1/en not_active Abandoned
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