DK0517986T3 - Transformerede erythrocytter, fremgangsmåde til fremstilling af samme og deres anvendelse i farmaceutiske præparater - Google Patents

Transformerede erythrocytter, fremgangsmåde til fremstilling af samme og deres anvendelse i farmaceutiske præparater

Info

Publication number
DK0517986T3
DK0517986T3 DK91401602.7T DK91401602T DK0517986T3 DK 0517986 T3 DK0517986 T3 DK 0517986T3 DK 91401602 T DK91401602 T DK 91401602T DK 0517986 T3 DK0517986 T3 DK 0517986T3
Authority
DK
Denmark
Prior art keywords
preparing
processes
same
pharmaceutical compositions
erythrocytes
Prior art date
Application number
DK91401602.7T
Other languages
English (en)
Inventor
Mauro Magnani
Luigia Rossi
Original Assignee
Europ Communities
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Europ Communities filed Critical Europ Communities
Application granted granted Critical
Publication of DK0517986T3 publication Critical patent/DK0517986T3/da

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
    • A61K9/50—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals
    • A61K9/5005—Wall or coating material
    • A61K9/5063—Compounds of unknown constitution, e.g. material from plants or animals
    • A61K9/5068—Cell membranes or bacterial membranes enclosing drugs
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
    • A61K35/12—Materials from mammals; Compositions comprising non-specified tissues or cells; Compositions comprising non-embryonic stem cells; Genetically modified cells
    • A61K35/14—Blood; Artificial blood
    • A61K35/18—Erythrocytes
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A61P31/14—Antivirals for RNA viruses
    • A61P31/18—Antivirals for RNA viruses for HIV
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Virology (AREA)
  • Engineering & Computer Science (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Cell Biology (AREA)
  • Zoology (AREA)
  • Epidemiology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Molecular Biology (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Hematology (AREA)
  • Developmental Biology & Embryology (AREA)
  • Communicable Diseases (AREA)
  • Oncology (AREA)
  • Biomedical Technology (AREA)
  • Botany (AREA)
  • Biotechnology (AREA)
  • Biophysics (AREA)
  • Immunology (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • AIDS & HIV (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
DK91401602.7T 1991-06-14 1991-06-14 Transformerede erythrocytter, fremgangsmåde til fremstilling af samme og deres anvendelse i farmaceutiske præparater DK0517986T3 (da)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
EP91401602A EP0517986B1 (en) 1991-06-14 1991-06-14 Transformed erythrocytes, process for preparing the same, and their use in pharmaceutical compositions

Publications (1)

Publication Number Publication Date
DK0517986T3 true DK0517986T3 (da) 1998-03-30

Family

ID=8208584

Family Applications (1)

Application Number Title Priority Date Filing Date
DK91401602.7T DK0517986T3 (da) 1991-06-14 1991-06-14 Transformerede erythrocytter, fremgangsmåde til fremstilling af samme og deres anvendelse i farmaceutiske præparater

Country Status (10)

Country Link
US (1) US5753221A (da)
EP (1) EP0517986B1 (da)
JP (1) JPH06510742A (da)
AT (1) ATE157879T1 (da)
CA (1) CA2102619A1 (da)
DE (1) DE69127615T2 (da)
DK (1) DK0517986T3 (da)
ES (1) ES2109260T3 (da)
GR (1) GR3025488T3 (da)
WO (1) WO1992022306A1 (da)

Families Citing this family (21)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5409710A (en) * 1993-04-20 1995-04-25 Endocon, Inc. Foam cell drug delivery
HUT76331A (en) * 1994-07-15 1997-08-28 Lepetit Spa Dinucleoside-5',5'-pyrophosphates
DE69732225T2 (de) * 1997-05-05 2005-06-23 Dideco S.R.L., Mirandola Verfahren zur Verkapselung von biologisch aktiven Stoffen in Erythrocyten und Gerät dafür
CA2332986C (en) 1998-05-26 2009-09-08 Lifecell Corporation Cryopreservation of human red blood cells
US20100040546A1 (en) * 2008-08-13 2010-02-18 Searete Llc, A Limited Liability Corporation Of The State Of Delaware Biological targeting compositions and methods of using the same
US8211656B2 (en) 2008-08-13 2012-07-03 The Invention Science Fund I, Llc Biological targeting compositions and methods of using the same
US20120034156A1 (en) * 2010-08-03 2012-02-09 Searete Llc, A Limited Liability Corporation Of The State Of Delaware Artificial cells
US20100042072A1 (en) * 2008-08-13 2010-02-18 Searete Llc, A Limited Liability Corporation Of The State Of Delaware Biological targeting compositions and methods of using the same
WO2010025322A2 (en) * 2008-08-28 2010-03-04 The Florida International University Board Of Trustees Magnetic nanodelivery of therapeutic agents across the blood brain barrier
EP3071515A2 (en) 2013-11-18 2016-09-28 Rubius Therapeutics, Inc. Synthetic membrane-receiver complexes
BR112016022814A8 (pt) 2014-04-01 2021-07-06 Rubius Therapeutics Inc composição farmacêutica e seu método de preparação, ácido nucleico, e dispositivo médico ou kit médico
KR20200104887A (ko) 2017-12-23 2020-09-04 루비우스 테라퓨틱스, 아이엔씨. 인공 항원 제시 세포 및 사용 방법
RU2020132924A (ru) 2018-03-08 2022-04-11 Рубиус Терапьютикс, Инк. Терапевтические клеточные системы и способы лечения рака и инфекционных заболеваний
EP3958877A1 (en) 2019-04-26 2022-03-02 Rubius Therapeutics, Inc. Buffered compositions including enucleated erythroid cells
JP2022533252A (ja) 2019-05-24 2022-07-21 ルビウス セラピューティクス， インコーポレイテッド 脱核赤血球細胞を生成する方法
US20210130780A1 (en) 2019-11-04 2021-05-06 Rubius Therapeutics, Inc. Methods of generating enucleated erythroid cells using myo-inositol
EP4055148A1 (en) 2019-11-04 2022-09-14 Rubius Therapeutics, Inc. Methods of generating enucleated erythroid cells using taurine or hypotaurine
WO2022150578A1 (en) 2021-01-08 2022-07-14 Rubius Therapeutics, Inc. Methods of treating a tumor in a human subject
TW202241471A (zh) 2021-01-08 2022-11-01 美商盧比亞斯治療公司 提高個體中NKp30陽性淋巴球的方法及其用途
TW202304482A (zh) 2021-03-14 2023-02-01 美商盧比亞斯治療公司 於個體中增加nkg2d陽性淋巴球之方法及其用途
TW202317179A (zh) 2021-06-03 2023-05-01 美商盧比亞斯治療公司 在個體中治療ｈｐｖ１６－陽性或ｈｐｖ１６－相關的癌症之方法

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2529463B1 (fr) * 1982-07-05 1986-01-10 Centre Nat Rech Scient Procede et dispositif pour l'encapsulation dans les erythrocytes d'au moins une substance a activite biologique, notamment des effecteurs allosteriques de l'hemoglobine et erythrocytes ainsi obtenus
IL86650A0 (en) * 1987-06-30 1988-11-30 Biophor Corp Animal derived cells and liposomes,having an antigenic protein incorporated into their membrane
FR2653561A1 (fr) * 1989-10-19 1991-04-26 Fondation Nale Transfusion San Hetero-anticorps anti-rhd et composition pharmaceutique les contenant.

Also Published As

Publication number Publication date
DE69127615D1 (de) 1997-10-16
GR3025488T3 (en) 1998-02-27
EP0517986A1 (en) 1992-12-16
EP0517986B1 (en) 1997-09-10
ATE157879T1 (de) 1997-09-15
DE69127615T2 (de) 1998-03-19
JPH06510742A (ja) 1994-12-01
ES2109260T3 (es) 1998-01-16
US5753221A (en) 1998-05-19
CA2102619A1 (en) 1992-12-15
WO1992022306A1 (en) 1992-12-23

Similar Documents

Publication Publication Date Title
DK0517986T3 (da) Transformerede erythrocytter, fremgangsmåde til fremstilling af samme og deres anvendelse i farmaceutiske præparater
DK552684A (da) Desulfatohirudiner samt deres fremstilling og anvendelse
DK0503548T3 (da) Cykliske ureaderivater, lægemidler indeholdende disse, og fremgangsmåde til deres fremstilling.
ATE114113T1 (de) Verwendung von droloxifen bei der behandlung von knochenerkrankungen.
DK0791571T3 (da) Benzoylderivater
DK1200418T3 (da) Nematodicide trifluorbutener
ES2051641B1 (es) Procedimientos para la preparacion de compuestos derivados de tiourea.
DK0513543T3 (da) Amidinophenylalaninderivater, fremgangsmåde til deres fremstilling, deres anvendelse og antikoagulationsmidler med indehold deraf
FI913478A0 (fi) Diazinderivat.
BR0012970A (pt) Compostos e composições antipicornavirais, seus usos farmacêuticos e materiais para a sua sìntese
DK0497816T3 (da) Behandling af HIV-infektioner og forbindelser anvendelige derved
DK0516588T3 (da) Substituerede diaminophthalimider og analoger
TR200101649T2 (tr) Piperazin türevleri.
FI945975A (fi) Haarautuneella aminoryhmällä substituoituja tiatsoleja, menetelmiä niiden valmistamiseksi ja niitä sisältäviä farmaseuttisia koostumuksia
DK161642C (da) Phenoxy- eller phenylthioalkanderivater, skadedyrsbekaempende praeparat indeholdende saadanne derivater samt fremgangsmaade til bekaempelse af insekter og acari
DK462687A (da) Forbindelse til behandling af retrovirusinfektioner.
EE200100125A (et) TAN-1057 derivaadid
DK0750616T3 (da) Syreadditionssalte af 2,3,4,5-tetrahydro-1H-3-benzazapinforbindelser
DK418986D0 (da) Pyrrolobenzimidazoler, pyrrolobenzoxazoler og pyrrolobenzthiazoler, fremgangsmaader til fremstilling heraf og laegemidler med indhold heraf
DK47688D0 (da) 5-(3-alkyl-5-tert.butyl-4-hydroxyphenyl)-2-amino-6h-1,3,4-thiadiaziner, deres fremstilling og anvendelse som laegemiddel
DK190983A (da) 2,4-diamino-5-(substituerede)pyrimidiner, fremgangsmaade til deres fremstilling og mellemprodukter derfor
DE69402004D1 (de) Beta-mercapto-propanamidderivate verwendbar zur Behandlung kardiovaskularer Krankheiten oder Erkrankungen
DK0538690T3 (da) Arylquinolyl-substituerede 1,4-dihydropyridin-dicarboxylsyrederivater, fremgangsmåde til deres fremstilling af deres anvendelse i lægemidler
DK0470989T3 (da) Anvendelse af monoklonale anti-beta2 mikroglobulin antistoffer
TH9666EX (th) นิวคลีโอไซด์ที่ใช้ในการรักษาโรค