DE69127615T2 - Transformierte Erythrozyten, Verfahren zu deren Herstellung, und ihre Verwendung in pharmazeutischen Zusammensetzungen - Google Patents
Transformierte Erythrozyten, Verfahren zu deren Herstellung, und ihre Verwendung in pharmazeutischen ZusammensetzungenInfo
- Publication number
- DE69127615T2 DE69127615T2 DE69127615T DE69127615T DE69127615T2 DE 69127615 T2 DE69127615 T2 DE 69127615T2 DE 69127615 T DE69127615 T DE 69127615T DE 69127615 T DE69127615 T DE 69127615T DE 69127615 T2 DE69127615 T2 DE 69127615T2
- Authority
- DE
- Germany
- Prior art keywords
- processes
- preparation
- pharmaceutical compositions
- erythrocytes
- transformed
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Fee Related
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
- A61K9/50—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals
- A61K9/5005—Wall or coating material
- A61K9/5063—Compounds of unknown constitution, e.g. material from plants or animals
- A61K9/5068—Cell membranes or bacterial membranes enclosing drugs
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
- A61K35/12—Materials from mammals; Compositions comprising non-specified tissues or cells; Compositions comprising non-embryonic stem cells; Genetically modified cells
- A61K35/14—Blood; Artificial blood
- A61K35/18—Erythrocytes
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
- A61P31/14—Antivirals for RNA viruses
- A61P31/18—Antivirals for RNA viruses for HIV
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Veterinary Medicine (AREA)
- Chemical & Material Sciences (AREA)
- Engineering & Computer Science (AREA)
- Animal Behavior & Ethology (AREA)
- Medicinal Chemistry (AREA)
- Virology (AREA)
- Public Health (AREA)
- Pharmacology & Pharmacy (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Epidemiology (AREA)
- Zoology (AREA)
- Cell Biology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Molecular Biology (AREA)
- Communicable Diseases (AREA)
- Immunology (AREA)
- Oncology (AREA)
- Botany (AREA)
- Biophysics (AREA)
- Developmental Biology & Embryology (AREA)
- Hematology (AREA)
- Biomedical Technology (AREA)
- Biotechnology (AREA)
- Tropical Medicine & Parasitology (AREA)
- AIDS & HIV (AREA)
- Medicines Containing Material From Animals Or Micro-Organisms (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
EP91401602A EP0517986B1 (de) | 1991-06-14 | 1991-06-14 | Transformierte Erythrozyten, Verfahren zu deren Herstellung, und ihre Verwendung in pharmazeutischen Zusammensetzungen |
Publications (2)
Publication Number | Publication Date |
---|---|
DE69127615D1 DE69127615D1 (de) | 1997-10-16 |
DE69127615T2 true DE69127615T2 (de) | 1998-03-19 |
Family
ID=8208584
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
DE69127615T Expired - Fee Related DE69127615T2 (de) | 1991-06-14 | 1991-06-14 | Transformierte Erythrozyten, Verfahren zu deren Herstellung, und ihre Verwendung in pharmazeutischen Zusammensetzungen |
Country Status (10)
Country | Link |
---|---|
US (1) | US5753221A (de) |
EP (1) | EP0517986B1 (de) |
JP (1) | JPH06510742A (de) |
AT (1) | ATE157879T1 (de) |
CA (1) | CA2102619A1 (de) |
DE (1) | DE69127615T2 (de) |
DK (1) | DK0517986T3 (de) |
ES (1) | ES2109260T3 (de) |
GR (1) | GR3025488T3 (de) |
WO (1) | WO1992022306A1 (de) |
Families Citing this family (21)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US5409710A (en) * | 1993-04-20 | 1995-04-25 | Endocon, Inc. | Foam cell drug delivery |
ES2129893T3 (es) * | 1994-07-15 | 1999-06-16 | Biosearch Italia Spa | Dinucleosido-5',5'-pirofosfatos. |
EP0882448B1 (de) * | 1997-05-05 | 2005-01-12 | DIDECO S.r.l. | Verfahren zur Verkapselung von biologisch aktiven Stoffen in Erythrocyten und Gerät dafür |
AU758703C (en) | 1998-05-26 | 2004-06-03 | Lifecell Corporation | Cryopreservation of human red blood cells |
US20100042072A1 (en) * | 2008-08-13 | 2010-02-18 | Searete Llc, A Limited Liability Corporation Of The State Of Delaware | Biological targeting compositions and methods of using the same |
US20100040546A1 (en) * | 2008-08-13 | 2010-02-18 | Searete Llc, A Limited Liability Corporation Of The State Of Delaware | Biological targeting compositions and methods of using the same |
US8211656B2 (en) | 2008-08-13 | 2012-07-03 | The Invention Science Fund I, Llc | Biological targeting compositions and methods of using the same |
US20120034156A1 (en) * | 2010-08-03 | 2012-02-09 | Searete Llc, A Limited Liability Corporation Of The State Of Delaware | Artificial cells |
WO2010025322A2 (en) * | 2008-08-28 | 2010-03-04 | The Florida International University Board Of Trustees | Magnetic nanodelivery of therapeutic agents across the blood brain barrier |
EP3071515A2 (de) | 2013-11-18 | 2016-09-28 | Rubius Therapeutics, Inc. | Synthetische membran-empfänger-komplexe |
HUE054471T2 (hu) | 2014-04-01 | 2021-09-28 | Rubius Therapeutics Inc | Immunmodulációs módszerek és készítmények |
RU2763798C1 (ru) | 2017-12-23 | 2022-01-11 | Рубиус Терапьютикс, Инк. | Искусственные антигенпрезентирующие клетки и способы их применения |
SG11202008261WA (en) | 2018-03-08 | 2020-09-29 | Rubius Therapeutics Inc | Therapeutic cell systems and methods for treating cancer and infectious diseases |
AU2020263513A1 (en) | 2019-04-26 | 2021-11-18 | Rubius Therapeutics, Inc. | Buffered compositions including enucleated erythroid cells |
CA3141315A1 (en) | 2019-05-24 | 2020-12-03 | Rubius Therapeutics, Inc. | Methods of generating enucleated erythroid cells |
CA3160464A1 (en) | 2019-11-04 | 2021-05-14 | Rubius Therapeutics, Inc. | Methods of generating enucleated erythroid cells using taurine or hypotaurine |
JP2023500327A (ja) | 2019-11-04 | 2023-01-05 | ルビウス セラピューティクス, インコーポレイテッド | ミオイノシトールを使用して除核赤芽球細胞を生成する方法 |
TW202241471A (zh) | 2021-01-08 | 2022-11-01 | 美商盧比亞斯治療公司 | 提高個體中NKp30陽性淋巴球的方法及其用途 |
WO2022150578A1 (en) | 2021-01-08 | 2022-07-14 | Rubius Therapeutics, Inc. | Methods of treating a tumor in a human subject |
TW202304482A (zh) | 2021-03-14 | 2023-02-01 | 美商盧比亞斯治療公司 | 於個體中增加nkg2d陽性淋巴球之方法及其用途 |
TW202317179A (zh) | 2021-06-03 | 2023-05-01 | 美商盧比亞斯治療公司 | 在個體中治療hpv16-陽性或hpv16-相關的癌症之方法 |
Family Cites Families (3)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
FR2529463B1 (fr) * | 1982-07-05 | 1986-01-10 | Centre Nat Rech Scient | Procede et dispositif pour l'encapsulation dans les erythrocytes d'au moins une substance a activite biologique, notamment des effecteurs allosteriques de l'hemoglobine et erythrocytes ainsi obtenus |
IL86650A0 (en) * | 1987-06-30 | 1988-11-30 | Biophor Corp | Animal derived cells and liposomes,having an antigenic protein incorporated into their membrane |
FR2653561A1 (fr) * | 1989-10-19 | 1991-04-26 | Fondation Nale Transfusion San | Hetero-anticorps anti-rhd et composition pharmaceutique les contenant. |
-
1991
- 1991-06-14 EP EP91401602A patent/EP0517986B1/de not_active Expired - Lifetime
- 1991-06-14 DK DK91401602.7T patent/DK0517986T3/da active
- 1991-06-14 AT AT91401602T patent/ATE157879T1/de not_active IP Right Cessation
- 1991-06-14 DE DE69127615T patent/DE69127615T2/de not_active Expired - Fee Related
- 1991-06-14 ES ES91401602T patent/ES2109260T3/es not_active Expired - Lifetime
-
1992
- 1992-06-09 JP JP4510441A patent/JPH06510742A/ja active Pending
- 1992-06-09 WO PCT/EP1992/001291 patent/WO1992022306A1/en active Application Filing
- 1992-06-09 US US08/146,060 patent/US5753221A/en not_active Expired - Fee Related
- 1992-06-09 CA CA002102619A patent/CA2102619A1/en not_active Abandoned
-
1997
- 1997-11-26 GR GR970403137T patent/GR3025488T3/el unknown
Also Published As
Publication number | Publication date |
---|---|
ATE157879T1 (de) | 1997-09-15 |
ES2109260T3 (es) | 1998-01-16 |
DE69127615D1 (de) | 1997-10-16 |
WO1992022306A1 (en) | 1992-12-23 |
CA2102619A1 (en) | 1992-12-15 |
JPH06510742A (ja) | 1994-12-01 |
EP0517986B1 (de) | 1997-09-10 |
US5753221A (en) | 1998-05-19 |
GR3025488T3 (en) | 1998-02-27 |
DK0517986T3 (da) | 1998-03-30 |
EP0517986A1 (de) | 1992-12-16 |
Similar Documents
Publication | Publication Date | Title |
---|---|---|
DE69127615D1 (de) | Transformierte Erythrozyten, Verfahren zu deren Herstellung, und ihre Verwendung in pharmazeutischen Zusammensetzungen | |
ATE56021T1 (de) | Desulfatohirudine, verfahren zu ihrer herstellung und pharmazeutische mittel. | |
ATE83659T1 (de) | Verwendung von indolon-derivaten zur herstellung von arzneimitteln zur behandlung des parkinsonismus. | |
NO902800L (no) | Fremgangsmaate for fremstilling av 11beta-aryl-4-oestrener. | |
DE59209965D1 (de) | Chinoxaline, Verfahren zu ihrer Herstellung und ihre Verwendung | |
DE68906609D1 (de) | Dopamin-vorlaeufer. | |
NL960024I2 (nl) | Farmaceutisch preparaat omvattend 3'-deoxythymidine-2'-een (3'-deoxy-2',3'-didehydrothymidine) voor de behandeling van met retrovirus besmette patiënten. | |
FI945975A (fi) | Haarautuneella aminoryhmällä substituoituja tiatsoleja, menetelmiä niiden valmistamiseksi ja niitä sisältäviä farmaseuttisia koostumuksia | |
DE59200277D1 (de) | Substituierte Diaminophthalimide und Analoga. | |
ES2160643T3 (es) | Composiciones que contienen g-csf y proteina de union al tnf. | |
ATE127020T1 (de) | Pharmazeutische zusammensetzungen mit eierschalenbestandteilen und ihre herstellung und verwendung. | |
ATE80039T1 (de) | Pharmazeutische zusammensetzung, enthaltend 2',3'-dideoxycytidin-2'-en(2',3'-dideoxy-2',3'didehydrocytidin) zur behandlung von mit retrovirus infizierten patienten. | |
DE3887068D1 (de) | 2,2-Dimethylchromenderivate, Verfahren zur Herstellung und diese enthaltende pharmazeutische Zusammenstellungen. | |
ATE66230T1 (de) | Neue pyrrolo-benzimidazole, verfahren zu ihrer herstellung und diese verbindungen enthaltende arzneimittel. | |
FR2707638B1 (fr) | Nouveaux dérivés d'amino-acides, leurs procédés de préparation et leur application thérapeutique. | |
ATE141796T1 (de) | 2',5'-oligoadenylat-derivate zur verwendung als heilmittel | |
DE59008921D1 (de) | Dibenzo(1,5)dioxocin-5-one-Derivate, ihre Verwendung in Arzneimitteln und Verfahren zu ihrer Herstellung. | |
FR2635527B1 (fr) | Il2 humaine recombinante non glycosylee sous forme reduite, son procede d'obtention et son application comme medicament | |
EP0129891A3 (de) | Chinazolinon-Derivate, Verfahren zu deren Herstellung und diese enthaltende pharmazeutische Zusammensetzungen | |
ATE112276T1 (de) | Aryl-chinolyl-substituierte 1,4-dihydropyridin- dicarbonsäurederivate, verfahren zu ihrer herstellung und ihre verwendung in arzneimitteln. | |
KR890001555A (ko) | 요산 배설용 조성물 | |
ATE101119T1 (de) | Butensaeure-amide, deren salze, diese enthaltende pharmazeutische zusammensetzungen und verfahren zu deren herstellung. | |
ATE105192T1 (de) | Methode fuer die kontrolle von chronischer atmungskrankheit und nekrotischer enteritis bei voegeln. |
Legal Events
Date | Code | Title | Description |
---|---|---|---|
8364 | No opposition during term of opposition | ||
8339 | Ceased/non-payment of the annual fee |