ATE157879T1 - Transformierte erythrozyten, verfahren zu deren herstellung, und ihre verwendung in pharmazeutischen zusammensetzungen - Google Patents
Transformierte erythrozyten, verfahren zu deren herstellung, und ihre verwendung in pharmazeutischen zusammensetzungenInfo
- Publication number
- ATE157879T1 ATE157879T1 AT91401602T AT91401602T ATE157879T1 AT E157879 T1 ATE157879 T1 AT E157879T1 AT 91401602 T AT91401602 T AT 91401602T AT 91401602 T AT91401602 T AT 91401602T AT E157879 T1 ATE157879 T1 AT E157879T1
- Authority
- AT
- Austria
- Prior art keywords
- production
- erythrocytes
- pharmaceutical compositions
- transformed
- compositions
- Prior art date
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
- A61K9/50—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals
- A61K9/5005—Wall or coating material
- A61K9/5063—Compounds of unknown constitution, e.g. material from plants or animals
- A61K9/5068—Cell membranes or bacterial membranes enclosing drugs
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
- A61K35/12—Materials from mammals; Compositions comprising non-specified tissues or cells; Compositions comprising non-embryonic stem cells; Genetically modified cells
- A61K35/14—Blood; Artificial blood
- A61K35/18—Erythrocytes
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
- A61P31/14—Antivirals for RNA viruses
- A61P31/18—Antivirals for RNA viruses for HIV
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
EP91401602A EP0517986B1 (de) | 1991-06-14 | 1991-06-14 | Transformierte Erythrozyten, Verfahren zu deren Herstellung, und ihre Verwendung in pharmazeutischen Zusammensetzungen |
Publications (1)
Publication Number | Publication Date |
---|---|
ATE157879T1 true ATE157879T1 (de) | 1997-09-15 |
Family
ID=8208584
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
AT91401602T ATE157879T1 (de) | 1991-06-14 | 1991-06-14 | Transformierte erythrozyten, verfahren zu deren herstellung, und ihre verwendung in pharmazeutischen zusammensetzungen |
Country Status (10)
Country | Link |
---|---|
US (1) | US5753221A (de) |
EP (1) | EP0517986B1 (de) |
JP (1) | JPH06510742A (de) |
AT (1) | ATE157879T1 (de) |
CA (1) | CA2102619A1 (de) |
DE (1) | DE69127615T2 (de) |
DK (1) | DK0517986T3 (de) |
ES (1) | ES2109260T3 (de) |
GR (1) | GR3025488T3 (de) |
WO (1) | WO1992022306A1 (de) |
Families Citing this family (21)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US5409710A (en) * | 1993-04-20 | 1995-04-25 | Endocon, Inc. | Foam cell drug delivery |
NZ290127A (en) * | 1994-07-15 | 1998-05-27 | Lepetit Spa | Dinucleoside-5',5'-p1,p2-pyrophosphates; medicaments for treating tumours and viral infections |
EP0882448B1 (de) * | 1997-05-05 | 2005-01-12 | DIDECO S.r.l. | Verfahren zur Verkapselung von biologisch aktiven Stoffen in Erythrocyten und Gerät dafür |
ATE316757T1 (de) | 1998-05-26 | 2006-02-15 | Lifecell Corp | Cryokonservierung menschlicher roter blutzellen |
US20120034157A1 (en) * | 2010-08-03 | 2012-02-09 | Searete Llc, A Limited Liability Corporation Of The State Of Delaware | Artificial cells |
US8211656B2 (en) | 2008-08-13 | 2012-07-03 | The Invention Science Fund I, Llc | Biological targeting compositions and methods of using the same |
US20100042072A1 (en) * | 2008-08-13 | 2010-02-18 | Searete Llc, A Limited Liability Corporation Of The State Of Delaware | Biological targeting compositions and methods of using the same |
US20100040546A1 (en) * | 2008-08-13 | 2010-02-18 | Searete Llc, A Limited Liability Corporation Of The State Of Delaware | Biological targeting compositions and methods of using the same |
US20110213193A1 (en) * | 2008-08-28 | 2011-09-01 | The Florida International University Board Of Trustees | Magnetic Nanodelivery of Therapeutic Agents Across the Blood Brain Barrier |
WO2015073587A2 (en) | 2013-11-18 | 2015-05-21 | Rubius Therapeutics, Inc. | Synthetic membrane-receiver complexes |
EP3125927B1 (de) | 2014-04-01 | 2021-01-27 | Rubius Therapeutics, Inc. | Verfahren und zusammensetzungen zur immunmodulation |
SG11202005203UA (en) | 2017-12-23 | 2020-07-29 | Rubius Therapeutics Inc | Artificial antigen presenting cells and methods of use |
RU2020132924A (ru) | 2018-03-08 | 2022-04-11 | Рубиус Терапьютикс, Инк. | Терапевтические клеточные системы и способы лечения рака и инфекционных заболеваний |
JP2022530130A (ja) | 2019-04-26 | 2022-06-27 | ルビウス セラピューティクス, インコーポレイテッド | 除核赤血球細胞を含む緩衝組成物 |
CA3141315A1 (en) | 2019-05-24 | 2020-12-03 | Rubius Therapeutics, Inc. | Methods of generating enucleated erythroid cells |
WO2021092047A1 (en) | 2019-11-04 | 2021-05-14 | Rubius Therapeutics, Inc. | Methods of generating enucleated erythroid cells using taurine or hypotaurine |
CN115038784A (zh) | 2019-11-04 | 2022-09-09 | 鲁比厄斯治疗法股份有限公司 | 使用肌-肌醇产生去核红系细胞的方法 |
TW202241471A (zh) | 2021-01-08 | 2022-11-01 | 美商盧比亞斯治療公司 | 提高個體中NKp30陽性淋巴球的方法及其用途 |
TW202241470A (zh) | 2021-01-08 | 2022-11-01 | 美商盧比亞斯治療公司 | 治療人類個體腫瘤之方法 |
TW202304482A (zh) | 2021-03-14 | 2023-02-01 | 美商盧比亞斯治療公司 | 於個體中增加nkg2d陽性淋巴球之方法及其用途 |
TW202317179A (zh) | 2021-06-03 | 2023-05-01 | 美商盧比亞斯治療公司 | 在個體中治療hpv16-陽性或hpv16-相關的癌症之方法 |
Family Cites Families (3)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
FR2529463B1 (fr) * | 1982-07-05 | 1986-01-10 | Centre Nat Rech Scient | Procede et dispositif pour l'encapsulation dans les erythrocytes d'au moins une substance a activite biologique, notamment des effecteurs allosteriques de l'hemoglobine et erythrocytes ainsi obtenus |
IL86650A0 (en) * | 1987-06-30 | 1988-11-30 | Biophor Corp | Animal derived cells and liposomes,having an antigenic protein incorporated into their membrane |
FR2653561A1 (fr) * | 1989-10-19 | 1991-04-26 | Fondation Nale Transfusion San | Hetero-anticorps anti-rhd et composition pharmaceutique les contenant. |
-
1991
- 1991-06-14 EP EP91401602A patent/EP0517986B1/de not_active Expired - Lifetime
- 1991-06-14 ES ES91401602T patent/ES2109260T3/es not_active Expired - Lifetime
- 1991-06-14 DK DK91401602.7T patent/DK0517986T3/da active
- 1991-06-14 AT AT91401602T patent/ATE157879T1/de not_active IP Right Cessation
- 1991-06-14 DE DE69127615T patent/DE69127615T2/de not_active Expired - Fee Related
-
1992
- 1992-06-09 WO PCT/EP1992/001291 patent/WO1992022306A1/en active Application Filing
- 1992-06-09 US US08/146,060 patent/US5753221A/en not_active Expired - Fee Related
- 1992-06-09 CA CA002102619A patent/CA2102619A1/en not_active Abandoned
- 1992-06-09 JP JP4510441A patent/JPH06510742A/ja active Pending
-
1997
- 1997-11-26 GR GR970403137T patent/GR3025488T3/el unknown
Also Published As
Publication number | Publication date |
---|---|
JPH06510742A (ja) | 1994-12-01 |
US5753221A (en) | 1998-05-19 |
EP0517986A1 (de) | 1992-12-16 |
DE69127615T2 (de) | 1998-03-19 |
GR3025488T3 (en) | 1998-02-27 |
WO1992022306A1 (en) | 1992-12-23 |
CA2102619A1 (en) | 1992-12-15 |
DE69127615D1 (de) | 1997-10-16 |
ES2109260T3 (es) | 1998-01-16 |
EP0517986B1 (de) | 1997-09-10 |
DK0517986T3 (da) | 1998-03-30 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
UEP | Publication of translation of european patent specification | ||
REN | Ceased due to non-payment of the annual fee |