JP2021175416A5 - - Google Patents

Download PDF

Info

Publication number
JP2021175416A5
JP2021175416A5 JP2021131884A JP2021131884A JP2021175416A5 JP 2021175416 A5 JP2021175416 A5 JP 2021175416A5 JP 2021131884 A JP2021131884 A JP 2021131884A JP 2021131884 A JP2021131884 A JP 2021131884A JP 2021175416 A5 JP2021175416 A5 JP 2021175416A5
Authority
JP
Japan
Prior art keywords
manifold
pressure
perfusion
reservoirs
pressure manifold
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
JP2021131884A
Other languages
English (en)
Japanese (ja)
Other versions
JP2021175416A (ja
JP7387681B2 (ja
Filing date
Publication date
Priority claimed from JP2021069509A external-priority patent/JP6931434B2/ja
Application filed filed Critical
Publication of JP2021175416A publication Critical patent/JP2021175416A/ja
Publication of JP2021175416A5 publication Critical patent/JP2021175416A5/ja
Priority to JP2023194142A priority Critical patent/JP2024003181A/ja
Application granted granted Critical
Publication of JP7387681B2 publication Critical patent/JP7387681B2/ja
Active legal-status Critical Current
Anticipated expiration legal-status Critical

Links

JP2021131884A 2015-08-26 2021-08-13 灌流マニホールドアセンブリ Active JP7387681B2 (ja)

Priority Applications (1)

Application Number Priority Date Filing Date Title
JP2023194142A JP2024003181A (ja) 2015-08-26 2023-11-15 灌流マニホールドアセンブリ

Applications Claiming Priority (9)

Application Number Priority Date Filing Date Title
US201562210122P 2015-08-26 2015-08-26
US62/210,122 2015-08-26
US201562250861P 2015-11-04 2015-11-04
US62/250,861 2015-11-04
US201662361244P 2016-07-12 2016-07-12
US62/361,244 2016-07-12
US201662366482P 2016-07-25 2016-07-25
US62/366,482 2016-07-25
JP2021069509A JP6931434B2 (ja) 2015-08-26 2021-04-16 灌流マニホールドアセンブリ

Related Parent Applications (1)

Application Number Title Priority Date Filing Date
JP2021069509A Division JP6931434B2 (ja) 2015-08-26 2021-04-16 灌流マニホールドアセンブリ

Related Child Applications (1)

Application Number Title Priority Date Filing Date
JP2023194142A Division JP2024003181A (ja) 2015-08-26 2023-11-15 灌流マニホールドアセンブリ

Publications (3)

Publication Number Publication Date
JP2021175416A JP2021175416A (ja) 2021-11-04
JP2021175416A5 true JP2021175416A5 (enExample) 2022-01-25
JP7387681B2 JP7387681B2 (ja) 2023-11-28

Family

ID=57119971

Family Applications (6)

Application Number Title Priority Date Filing Date
JP2018511088A Active JP6608043B2 (ja) 2015-08-26 2016-08-26 灌流マニホールドアセンブリ
JP2019100979A Active JP6741826B2 (ja) 2015-08-26 2019-05-30 灌流マニホールドアセンブリ
JP2019100980A Active JP6871972B2 (ja) 2015-08-26 2019-05-30 灌流マニホールドアセンブリ
JP2021069509A Active JP6931434B2 (ja) 2015-08-26 2021-04-16 灌流マニホールドアセンブリ
JP2021131884A Active JP7387681B2 (ja) 2015-08-26 2021-08-13 灌流マニホールドアセンブリ
JP2023194142A Pending JP2024003181A (ja) 2015-08-26 2023-11-15 灌流マニホールドアセンブリ

Family Applications Before (4)

Application Number Title Priority Date Filing Date
JP2018511088A Active JP6608043B2 (ja) 2015-08-26 2016-08-26 灌流マニホールドアセンブリ
JP2019100979A Active JP6741826B2 (ja) 2015-08-26 2019-05-30 灌流マニホールドアセンブリ
JP2019100980A Active JP6871972B2 (ja) 2015-08-26 2019-05-30 灌流マニホールドアセンブリ
JP2021069509A Active JP6931434B2 (ja) 2015-08-26 2021-04-16 灌流マニホールドアセンブリ

Family Applications After (1)

Application Number Title Priority Date Filing Date
JP2023194142A Pending JP2024003181A (ja) 2015-08-26 2023-11-15 灌流マニホールドアセンブリ

Country Status (12)

Country Link
US (14) US10125342B2 (enExample)
EP (3) EP4026616B1 (enExample)
JP (6) JP6608043B2 (enExample)
KR (6) KR102605693B1 (enExample)
CN (2) CN114540192A (enExample)
AU (3) AU2016312678B2 (enExample)
BR (1) BR112018003614A2 (enExample)
CA (3) CA3053745C (enExample)
DK (1) DK3341465T3 (enExample)
GB (4) GB2601649B (enExample)
SG (1) SG10201811548PA (enExample)
WO (1) WO2017035484A1 (enExample)

Families Citing this family (60)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP4026616B1 (en) * 2015-08-26 2024-12-11 Emulate, Inc. Perfusion manifold assembly
CA3001954A1 (en) 2015-10-16 2017-04-20 Oxford University Innovation Limited Microfluidic arrangements
GB201614150D0 (en) 2016-08-18 2016-10-05 Univ Oxford Innovation Ltd Microfluidic arrangements
USD812766S1 (en) * 2016-07-12 2018-03-13 EMULATE, Inc. Microfluidic chip for use with a fluid perfusion module
USD860471S1 (en) * 2016-07-12 2019-09-17 EMULATE, Inc. Perfusion module lid
US10335788B2 (en) 2016-07-12 2019-07-02 EMULATE, Inc. Removing bubbles in a microfluidic device
WO2018013654A1 (en) 2016-07-12 2018-01-18 EMULATE, Inc. Additive channels
USD842493S1 (en) * 2016-09-07 2019-03-05 EMULATE, Inc. Microfluidic chip without pressure features for use with a fluid perfusion module
USD838864S1 (en) * 2016-09-07 2019-01-22 EMULATE, Inc. Opaque microfluidic chip without pressure features for use with a fluid perfusion module
USD816861S1 (en) * 2016-09-07 2018-05-01 EMULATE, Inc. Transparent microfluidic chip without pressure features for use with a fluid perfusion module
USD803173S1 (en) * 2016-09-07 2017-11-21 EMULATE, Inc. Perfusion module lid without pressure features
US11001796B2 (en) 2016-11-23 2021-05-11 The Charles Stark Draper Laboratory, Inc. Bi-layer multi-well cell culture platform
US11213824B2 (en) 2017-03-29 2022-01-04 The Research Foundation For The State University Of New York Microfluidic device and methods
US10508976B1 (en) * 2017-03-31 2019-12-17 Advanced Micro Instruments, Inc. Gas sampling device and method
AU2018262829A1 (en) 2017-05-04 2019-12-05 Ntnu - Norges Teknisk-Naturvitenskapelige Universitet Cell culture device
SG11201912152PA (en) * 2017-06-14 2020-01-30 Emulate Inc Effects of space travel on human brain cells
CA3076500C (en) * 2017-09-21 2025-07-08 Emulate Inc REOLOGICALLY BIOMIMITED FLUID SUBSTITUTE
WO2019063840A1 (de) * 2017-09-29 2019-04-04 MEDUCOMP GmbH Vorrichtung und verfahren zur mikrobiologischen prüfung von waschmaschinen
WO2019157136A2 (en) * 2018-02-07 2019-08-15 EMULATE, Inc. Gas mixer and pressurizer apparatus
GB201802819D0 (en) 2018-02-21 2018-04-04 Univ Oxford Innovation Ltd Methods and apparatus for manufacturing a microfluidic arrangement, and a microfluidic arrangement
WO2019195338A1 (en) * 2018-04-03 2019-10-10 EMULATE, Inc. Microfluidic control
US20200123484A1 (en) * 2018-10-22 2020-04-23 National Tsing Hua University Integrated chip and method for sperm sorting, oocyte incubation, and in vitro fertilization
JP7246041B2 (ja) * 2018-11-07 2023-03-27 ウシオ電機株式会社 細胞培養チップ及びその製造方法
US11725190B2 (en) 2019-02-22 2023-08-15 EMULATE, Inc. Microfluidic proximal tubule kidney-on-chip
US11841361B2 (en) 2019-02-22 2023-12-12 EMULATE, Inc. Microfluidic proximal tubule kidney-on-chip
WO2020216791A1 (en) * 2019-04-26 2020-10-29 Stilla Technologies Assembly for pressure controlled fluid release and its method therefore
WO2020236850A1 (en) * 2019-05-20 2020-11-26 Immunovalent Therapeutics Inc. Solid phase devices and methods of use for purifying and quantifying tissue-specific leukocytes
CN110205242B (zh) * 2019-06-18 2024-04-26 苏州锐讯生物科技有限公司 一种快速实现数字pcr反应的微流控芯片组件及其应用
FR3100033B1 (fr) * 2019-08-23 2021-11-05 Commissariat Energie Atomique Appareil pour mise en œuvre d'un procédé de traitement de fluide dans des conditions stériles
CN110523448B (zh) * 2019-09-03 2022-03-18 广东顺德工业设计研究院(广东顺德创新设计研究院) 微滴制备系统及制备方法
USD959017S1 (en) * 2019-09-30 2022-07-26 Tokyo Ohka Kogyo Co., Ltd. Container for cell observation
CA3158045A1 (en) * 2019-11-21 2021-05-27 Emulate Inc. Antibody producing microfluidic devices
JP7469795B2 (ja) * 2020-03-27 2024-04-17 学校法人東海大学 細胞培養装置
KR102808053B1 (ko) * 2020-04-20 2025-05-16 엠쥐아이 테크 컴퍼니 엘티디. 액체 스프레딩 장치, 액체 스프레딩 방법, 액체 스프레딩 시스템 및 조합 장치와 액체 통과 장치
TWI762948B (zh) * 2020-06-11 2022-05-01 豐康微流體晶片股份有限公司 應用於微流控晶片之快速拆接之密封匹配接頭模組
WO2022006505A1 (en) * 2020-07-02 2022-01-06 University Of Florida Research Foundation Perfusion-enabled bioreactor
CN111826273B (zh) * 2020-07-22 2023-03-21 上海逢伙泰企业管理有限公司 一种用于核酸检测的自动化全封闭微流控芯片
KR102451521B1 (ko) * 2020-08-25 2022-10-05 인제대학교 산학협력단 내장 장기칩 및 이의 제조방법
EP3964291A1 (en) * 2020-09-08 2022-03-09 Nederlandse Organisatie voor toegepast- natuurwetenschappelijk Onderzoek TNO Conditioning chamber for dual-interface fluidic system
WO2022122489A1 (de) * 2020-12-09 2022-06-16 Robert Bosch Gmbh INJEKTIONSSTÖßELPAKET FÜR EIN MIKROFLUIDIK-ANALYSESYSTEM SOWIE VERFAHREN UND MEHRKAVITÄTEN-SPRITZGIEßWERKZEUG ZU SEINER HERSTELLUNG
WO2022140342A1 (en) * 2020-12-23 2022-06-30 Parallel Fluidics Inc. Modular microfluidics platform
CN112280678B (zh) * 2020-12-25 2021-04-06 苏州大学 一种可拆卸、可重复使用的疏水或超疏水微流控器官芯片
CN112522081B (zh) * 2020-12-28 2022-09-27 上海揽微赛尔生物科技有限公司 一种细胞培养皿灌流装置
KR102293717B1 (ko) * 2021-06-29 2021-08-26 에스디바이오센서 주식회사 플로우 커버를 포함하는 유전체 추출 장치
WO2023047282A1 (en) * 2021-09-24 2023-03-30 3D Systems, Inc. Manifolds, systems and methods for conducting biological studies under flow
EP4194542A1 (en) * 2021-12-07 2023-06-14 Fluigent Apparatus for feeding a liquid medium to a fluidic system
CN116331644B (zh) * 2021-12-23 2025-07-29 财团法人工业技术研究院 细胞与组织层片成型包装与细胞灌注设备
KR20230143372A (ko) * 2022-04-05 2023-10-12 한림대학교 산학협력단 장기 모사 칩
KR20230143375A (ko) * 2022-04-05 2023-10-12 한림대학교 산학협력단 장기 모사 칩 구조체 제조방법
CA3154534A1 (en) * 2022-04-07 2023-10-07 Wasim Kapadia Microfluidic viscometer for measuring the viscosity of microliter-volume liquid samples
GB202205709D0 (en) * 2022-04-19 2022-06-01 Keratify Ltd Biological culture unit
KR20250024979A (ko) * 2022-06-15 2025-02-20 글로벌 라이프 사이언시즈 솔루션즈 유에스에이 엘엘씨 바이오 처리 시스템용 일회용 키트 및 배양 용기
CN115921222B (zh) * 2022-09-07 2023-11-28 常州铭赛机器人科技股份有限公司 螺杆阀的出胶控制方法
CN115541817B (zh) * 2022-09-19 2025-03-25 中铁十九局集团矿业投资有限公司 一种基岩面预爆裂检测装置及使用方法
US20240308229A1 (en) * 2023-03-15 2024-09-19 Funai Electric Co., Ltd. Hydrophilic foam having improved fluid retention
WO2024261063A1 (en) * 2023-06-23 2024-12-26 Eth Zurich Ex vivo tissue sampling system
TWI889052B (zh) * 2023-08-16 2025-07-01 新加坡商克雷多生醫股份有限公司 卡匣及其定量方法
EP4541459A1 (en) * 2023-10-18 2025-04-23 Livedrop A device for a microfluidic chip
EP4556119A1 (en) 2023-11-20 2025-05-21 Fluigent Liquid distribution system for a fluidic chip
CN118086053B (zh) * 2024-04-29 2024-07-09 四川迪亚生物科技集团有限公司 一种自灌流培养板及使用方法

Family Cites Families (206)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4207394A (en) * 1976-01-28 1980-06-10 Mcdonnell Douglas Corporation Process and apparatus for analyzing specimens for the presence of microorganisms therein
US4301414A (en) * 1979-10-29 1981-11-17 United States Surgical Corporation Disposable sample card and method of making same
US4397725A (en) * 1980-12-15 1983-08-09 Transidyne General Corp. Apparatus for measuring electrochemical activity
US4507707A (en) * 1981-12-30 1985-03-26 Willis John G Electro-pneumatic assembly device
US4682891A (en) * 1985-05-31 1987-07-28 Health Research, Incorporated Microcircle system
US4682890A (en) * 1985-05-31 1987-07-28 Health Research, Incorporated Microsample holder and carrier therefor
US4871439A (en) * 1987-02-05 1989-10-03 Steven Enzer Disposable self-calibratable electrode package
US4940527A (en) * 1987-06-01 1990-07-10 Abbott Laboratories Two-part test cartridge for centrifuge
US5236668A (en) * 1991-12-23 1993-08-17 Higdon William R Detachable column cartridge gas chromatograph
US5279797A (en) * 1992-10-05 1994-01-18 Avl Scientific Corporation Disposable liquid reagent cartridge and receptacle therefor
JP2948069B2 (ja) * 1993-09-20 1999-09-13 株式会社日立製作所 化学分析装置
FR2723735B1 (fr) * 1994-08-18 1996-10-31 Abx Sa Boitier a branchement automatique pour distribution de reactifs dans un appareil notamment un analyseur hematologique.
DE19546952C2 (de) * 1994-12-17 1999-06-17 Horiba Ltd Gasanalysator-Einschubanordnung
US5731212A (en) * 1994-12-20 1998-03-24 International Technidyne Corporation Test apparatus and method for testing cuvette accommodated samples
EP0807036B1 (en) * 1995-02-03 2002-05-29 Nvb International A/S Valve connector
US5609828A (en) * 1995-05-31 1997-03-11 bio M erieux Vitek, Inc. Sample card
US5856174A (en) * 1995-06-29 1999-01-05 Affymetrix, Inc. Integrated nucleic acid diagnostic device
US6399023B1 (en) * 1996-04-16 2002-06-04 Caliper Technologies Corp. Analytical system and method
US5885533A (en) * 1996-05-20 1999-03-23 Sendx Medical, Inc. Integral fluid and waste container for blood analyzer
US6016712A (en) * 1997-09-18 2000-01-25 Accumetrics Device for receiving and processing a sample
US6893877B2 (en) * 1998-01-12 2005-05-17 Massachusetts Institute Of Technology Methods for screening substances in a microwell array
US6095697A (en) * 1998-03-31 2000-08-01 Honeywell International Inc. Chip-to-interface alignment
GB9808836D0 (en) 1998-04-27 1998-06-24 Amersham Pharm Biotech Uk Ltd Microfabricated apparatus for cell based assays
CA2320296A1 (en) * 1998-05-18 1999-11-25 University Of Washington Liquid analysis cartridge
DE19854096A1 (de) * 1998-11-24 2000-05-25 Merck Patent Gmbh Anschlußträger für plattenförmige Mikrokomponenten
US6319476B1 (en) * 1999-03-02 2001-11-20 Perseptive Biosystems, Inc. Microfluidic connector
US6428053B1 (en) * 1999-03-12 2002-08-06 California Institute Of Technology Micromachined fluidic coupler and method of making the same
US6673620B1 (en) * 1999-04-20 2004-01-06 Cytologix Corporation Fluid exchange in a chamber on a microscope slide
US7759113B2 (en) 1999-04-30 2010-07-20 The General Hospital Corporation Fabrication of tissue lamina using microfabricated two-dimensional molds
JP2002542883A (ja) 1999-04-30 2002-12-17 マサチューセッツ ジェネラル ホスピタル 微細加工した2次元鋳型を用いる血管新生組織の加工
US7371400B2 (en) 2001-01-02 2008-05-13 The General Hospital Corporation Multilayer device for tissue engineering
US20020182749A1 (en) * 1999-05-11 2002-12-05 Aclara Biosciences, Inc. Sample evaporative control
US6555389B1 (en) * 1999-05-11 2003-04-29 Aclara Biosciences, Inc. Sample evaporative control
US7396444B2 (en) * 1999-06-22 2008-07-08 Agilent Technologies Inc. Device to operate a laboratory microchip
DE19928412C2 (de) * 1999-06-22 2002-03-21 Agilent Technologies Inc Versorgungselement für einen Labor-Mikrochip
US6692697B1 (en) * 1999-07-30 2004-02-17 Texas Instruments Incorporated Versatile flow cell front-end for optically-based integrated sensors
US20060128006A1 (en) 1999-11-10 2006-06-15 Gerhardt Antimony L Hydrodynamic capture and release mechanisms for particle manipulation
US20030091477A1 (en) * 1999-12-22 2003-05-15 Paul Eric A. Flow-thru chip cartridge, chip holder, system & method thereof
AU2001249071B2 (en) * 2000-02-23 2005-09-08 Caliper Life Sciences, Inc. Multi-reservoir pressure control system
US20050118073A1 (en) * 2003-11-26 2005-06-02 Fluidigm Corporation Devices and methods for holding microfluidic devices
WO2002040901A1 (en) * 2000-04-13 2002-05-23 California Institute Of Technology Micromachined rubber o-ring microfluidic couplers
US7776021B2 (en) 2000-04-28 2010-08-17 The Charles Stark Draper Laboratory Micromachined bilayer unit for filtration of small molecules
US7630063B2 (en) * 2000-08-02 2009-12-08 Honeywell International Inc. Miniaturized cytometer for detecting multiple species in a sample
US7641856B2 (en) * 2004-05-14 2010-01-05 Honeywell International Inc. Portable sample analyzer with removable cartridge
US7125540B1 (en) 2000-06-06 2006-10-24 Battelle Memorial Institute Microsystem process networks
US6864097B1 (en) * 2000-09-27 2005-03-08 Agilent Technologies, Inc. Arrays and their reading
US7208120B2 (en) 2000-09-27 2007-04-24 The Trustees Of Boston University Cellular diagnostic arrays, methods of using and processing for producing same
US20020146817A1 (en) * 2000-10-02 2002-10-10 Cannon Thomas F. Automated bioculture and bioculture experiments system
US6934836B2 (en) * 2000-10-06 2005-08-23 Protasis Corporation Fluid separation conduit cartridge with encryption capability
EP1330306A2 (en) * 2000-10-10 2003-07-30 BioTrove, Inc. Apparatus for assay, synthesis and storage, and methods of manufacture, use, and manipulation thereof
SE0004352D0 (sv) * 2000-11-27 2000-11-27 Helen Andersson System och metod för anslutning av vätskor i ett mikrofluidiskt flödescellsystem
WO2002064253A2 (en) * 2001-02-09 2002-08-22 Microchem Solutions Method and apparatus for sample injection in microfabricated devices
DE10106558C1 (de) * 2001-02-13 2002-11-07 Siemens Ag System zur automatisierten Behandlung von Fluiden, mit aneinanderreihbaren, austauschbaren Prozessmodulen
US7223363B2 (en) * 2001-03-09 2007-05-29 Biomicro Systems, Inc. Method and system for microfluidic interfacing to arrays
DE10111457B4 (de) * 2001-03-09 2006-12-14 Siemens Ag Diagnoseeinrichtung
KR100425536B1 (ko) * 2001-07-16 2004-03-30 학교법인 포항공과대학교 유체 마이크로칩용 브레드보드
US6749292B2 (en) * 2001-10-18 2004-06-15 Hewlett-Packard Development Company, L.P. Replaceable ink container for an inkjet printing system
US7189580B2 (en) 2001-10-19 2007-03-13 Wisconsin Alumni Research Foundation Method of pumping fluid through a microfluidic device
JP4439916B2 (ja) * 2001-12-19 2010-03-24 サウ ラン タン スターツ, マイクロ流体アレイ・デバイス用インターフェース部材およびホルダ
US7048893B2 (en) * 2002-02-06 2006-05-23 Sebia Mask for depositing and distributing reagents on an analytical support
US7189370B2 (en) * 2002-02-11 2007-03-13 Microchem Solutions Apparatus and methods for high throughput and high-resolution assays
US7189581B2 (en) * 2002-04-30 2007-03-13 Wisconsin Alumni Research Foundation Method of obtaining a sample concentration of a solution in a microfluidic device
AU2003232169B8 (en) * 2002-06-11 2008-05-08 Koninklijke Philips Electronics N.V. A disposable cartridge for characterizing particles suspended in a liquid
US7244961B2 (en) * 2002-08-02 2007-07-17 Silicon Valley Scientific Integrated system with modular microfluidic components
US7790443B2 (en) * 2002-08-27 2010-09-07 Vanderbilt University Bioreactors with substance injection capacity
DE60312186T2 (de) * 2002-09-06 2007-11-08 Epigem Ltd. Modulares mikrofluidsystem
EP2359689B1 (en) 2002-09-27 2015-08-26 The General Hospital Corporation Microfluidic device for cell separation and use thereof
EP1560642A4 (en) * 2002-10-09 2006-05-03 Univ Illinois MICROFLUID SYSTEMS AND COMPONENTS
US7932098B2 (en) * 2002-10-31 2011-04-26 Hewlett-Packard Development Company, L.P. Microfluidic system utilizing thin-film layers to route fluid
US7118708B2 (en) * 2002-11-12 2006-10-10 Automated Biotechnology, Inc. System of sample medium carriers with built-in memory elements and information input/output station for the carriers
CN100380034C (zh) * 2002-12-04 2008-04-09 斯宾克斯公司 流体的可程控微量控制用装置和方法
US20050266582A1 (en) * 2002-12-16 2005-12-01 Modlin Douglas N Microfluidic system with integrated permeable membrane
DE602004022508D1 (de) 2003-01-16 2009-09-24 Gen Hospital Corp Verwendung von dreidimensionalen, mikrogefertigten, mittels gewebetechnologie hergestellten systemen für pharmakologische anwendungen
US7435601B2 (en) * 2003-02-19 2008-10-14 Fitzco Incorporated Biological specimen handling method
US20040223874A1 (en) * 2003-03-31 2004-11-11 Canon Kabushiki Kaisha Biochemical reaction cartridge
WO2004094275A1 (en) 2003-04-17 2004-11-04 Cambridge International, Inc. Plastic woven spiral conveyor belt
US7960166B2 (en) 2003-05-21 2011-06-14 The General Hospital Corporation Microfabricated compositions and processes for engineering tissues containing multiple cell types
US7220244B2 (en) * 2003-08-04 2007-05-22 Bioquiddity, Inc. Infusion apparatus with constant force spring energy source
GB0320337D0 (en) * 2003-08-29 2003-10-01 Syrris Ltd A microfluidic system
US6972955B2 (en) * 2003-09-25 2005-12-06 Harris Corporation Electro-fluidic device and interconnect and related methods
JP4407271B2 (ja) * 2003-12-19 2010-02-03 株式会社日立製作所 チップ、反応分析装置、反応分析方法
US7666285B1 (en) * 2004-02-06 2010-02-23 University Of Central Florida Research Foundation, Inc. Portable water quality monitoring system
US7569127B1 (en) * 2004-02-06 2009-08-04 University Of Central Florida Research Foundation, Inc. Interconnecting microfluidic package and fabrication method
JP4464158B2 (ja) * 2004-02-13 2010-05-19 キヤノン株式会社 生化学反応カートリッジ
WO2005096751A2 (en) * 2004-04-02 2005-10-20 Eksigent Technologies Llc Microfluidic connections
US7465558B2 (en) * 2004-05-12 2008-12-16 Wyeth Perfusion system and apparatus for automated multi-channel patch-clamp recordings utilizing inside-out whole-cell configuration
US20060024702A1 (en) * 2004-05-12 2006-02-02 Connolly Dennis M Device, system, and method for detecting a target molecule in a sample
US8323564B2 (en) * 2004-05-14 2012-12-04 Honeywell International Inc. Portable sample analyzer system
JP2007537759A (ja) * 2004-05-19 2007-12-27 マサチューセッツ・インスティテュート・オブ・テクノロジー 灌流三次元細胞/組織疾患モデル
US7648792B2 (en) * 2004-06-25 2010-01-19 Ultracell Corporation Disposable component on a fuel cartridge and for use with a portable fuel cell system
US8329437B1 (en) * 2004-07-29 2012-12-11 E.I. Spectra, Llc Disposable particle counter cartridge
JP2008512128A (ja) * 2004-09-09 2008-04-24 マイクロフルイディク システムズ インコーポレイテッド 抽出装置及び試料準備方法
US7159848B2 (en) * 2004-09-10 2007-01-09 Agilent Technologies, Inc. Clamping systems
JP4455306B2 (ja) * 2004-12-13 2010-04-21 キヤノン株式会社 生化学処理方法
GB2421202B (en) * 2004-12-15 2009-12-09 Syrris Ltd Modular microfluidic system
US7582263B2 (en) * 2005-01-27 2009-09-01 Octrolix Bv Universal interface for a micro-fluidic chip
US7918980B2 (en) 2005-04-05 2011-04-05 George Mason Intellectual Properties, Inc. Electrocapturing flow cell
US8206650B2 (en) * 2005-04-12 2012-06-26 Chromedx Inc. Joint-diagnostic spectroscopic and biosensor meter
WO2006113527A2 (en) * 2005-04-14 2006-10-26 California Institute Of Technology Integrated chromatography devices and systems for monitoring analytes in real time and methods for manufacturing the same
EP1882189A2 (en) * 2005-04-20 2008-01-30 Fluidigm Corporation Analysis engine and database for manipulating parameters for fluidic systems on a chip
US9388374B2 (en) * 2005-07-07 2016-07-12 Emd Millipore Corporation Microfluidic cell culture systems
EP3029135B1 (en) 2005-07-07 2021-03-17 The Regents of the University of California Apparatus for cell culture array
US9637715B2 (en) * 2005-07-07 2017-05-02 Emd Millipore Corporation Cell culture and invasion assay method and system
US8257964B2 (en) 2006-01-04 2012-09-04 Cell ASIC Microwell cell-culture device and fabrication method
EP1929273B1 (en) * 2005-09-22 2017-07-05 Koninklijke Philips N.V. Detection and subsequent removal of an aperture blockage
US7790028B1 (en) 2005-09-28 2010-09-07 The Charles Stark Draper Laboratory, Inc. Systems, methods, and devices relating to a cellularized nephron unit
US7727371B2 (en) * 2005-10-07 2010-06-01 Caliper Life Sciences, Inc. Electrode apparatus for use with a microfluidic device
US9248421B2 (en) 2005-10-07 2016-02-02 Massachusetts Institute Of Technology Parallel integrated bioreactor device and method
US20070084706A1 (en) * 2005-10-18 2007-04-19 Shuichi Takayama Microfluidic cell culture device and method for using same
JP2007147456A (ja) * 2005-11-28 2007-06-14 Seiko Epson Corp マイクロ流体システム、試料分析装置、及び標的物質の検出または測定方法
US8173077B2 (en) * 2005-12-16 2012-05-08 The Curators Of The University Of Missouri Reusable PCR amplification system and method
US7976795B2 (en) 2006-01-19 2011-07-12 Rheonix, Inc. Microfluidic systems
US8501497B2 (en) * 2006-02-07 2013-08-06 Stokes Bio Limited Forming sample combinations using liquid bridge systems
JP2007292714A (ja) * 2006-03-29 2007-11-08 Seiko Epson Corp マイクロ流体システムおよび試料分析装置
US8795593B2 (en) * 2006-03-29 2014-08-05 Michael J. Nichols Instrument docking station for an automated testing system
US7560071B2 (en) * 2006-03-29 2009-07-14 Nichols Michael J Instrument docking station for an automated testing system
US8293524B2 (en) * 2006-03-31 2012-10-23 Fluxion Biosciences Inc. Methods and apparatus for the manipulation of particle suspensions and testing thereof
US7678338B2 (en) * 2006-04-07 2010-03-16 General Dynamics Armament And Technical Products Fluid retaining assembly and method of using the same
US7641860B2 (en) * 2006-06-01 2010-01-05 Nanotek, Llc Modular and reconfigurable multi-stage microreactor cartridge apparatus
DE102006030068A1 (de) 2006-06-28 2008-01-03 M2P-Labs Gmbh Vorrichtung und Verfahren zur Zu- und Abfuhr von Fluiden in geschüttelten Mikroreaktoren Arrays
EP1895308A1 (en) 2006-09-01 2008-03-05 Agilent Technologies, Inc. Droplet-based fluidic coupling
NL1032425C2 (nl) * 2006-09-04 2008-03-05 Micronit Microfluidics Bv Samenstel van ten minste één microfluïdische inrichting en een opzetstuk, opzetstuk en werkwijzen voor het vervaardigen en gebruik van zo een samenstel.
JP5553602B2 (ja) * 2006-09-06 2014-07-16 キヤノン ユー.エス. ライフ サイエンシズ, インコーポレイテッド マイクロ流体アッセイを実施するためのチップ及びカートリッジ設計構成
US8691164B2 (en) * 2007-04-20 2014-04-08 Celula, Inc. Cell sorting system and methods
CN103495439B (zh) * 2007-05-04 2015-09-16 欧普科诊断有限责任公司 流体连接器和微流体系统
US8465706B2 (en) 2007-06-20 2013-06-18 Trustees Of Columbia University In The City Of New York On-demand microfluidic droplet or bubble generation
WO2008156837A1 (en) 2007-06-20 2008-12-24 The Trustees Of Columbia University In The City Of New York On-demand microfluidic droplet or bubble generation
WO2009002152A1 (en) * 2007-06-26 2008-12-31 Micronit Microfluidics B.V. Device and method for fluidic coupling of fluidic conduits to a microfluidic chip, and uncoupling thereof
US8105783B2 (en) * 2007-07-13 2012-01-31 Handylab, Inc. Microfluidic cartridge
US8408892B2 (en) * 2007-10-05 2013-04-02 Snu R&Db Foundation Fluidic channel system and method for fabricating fine structure
US20090121476A1 (en) * 2007-11-08 2009-05-14 The Government Of The Us, As Represented By The Secretary Of The Navy Microfluidic Bus for Interconnecting Multiple Fluid Conduits
US7919062B2 (en) * 2008-03-20 2011-04-05 Corning Incorporated Modular microfluidic system and method for building a modular microfludic system
US8961902B2 (en) * 2008-04-23 2015-02-24 Bioscale, Inc. Method and apparatus for analyte processing
US20090301592A1 (en) * 2008-06-06 2009-12-10 Jochen Mueller Fluidic module connection
US8389294B2 (en) * 2008-06-09 2013-03-05 Wisconsin Alumni Research Foundation Microfluidic device and method for coupling discrete microchannels and for co-culture
KR102140055B1 (ko) * 2008-07-16 2020-07-31 칠드런'즈 메디컬 센터 코포레이션 마이크로채널을 갖는 기관 모방 장치 및 그 사용 및 제조 방법
CN102203605B (zh) * 2008-08-27 2014-07-23 生命技术公司 处理生物样品的设备和方法
US8133451B2 (en) * 2008-08-28 2012-03-13 Microfluidic Systems, Inc. Sample preparation apparatus
US9089844B2 (en) * 2010-11-01 2015-07-28 Bio-Rad Laboratories, Inc. System for forming emulsions
US20110229961A1 (en) * 2008-11-05 2011-09-22 Nanopoint, Inc. Active microfluidic system for in vitro culture
WO2010070521A1 (en) * 2008-12-18 2010-06-24 Koninklijke Philips Electronics N.V. Sensing device for sensing a fluid
JP5715068B2 (ja) * 2009-01-30 2015-05-07 マイクロニクス, インコーポレイテッド 携帯型高利得蛍光検出システム
JP5793427B2 (ja) * 2009-03-06 2015-10-14 ウオーターズ・テクノロジーズ・コーポレイシヨン マイクロ流体基板への電気機械および流体インターフェイス
WO2010111265A1 (en) * 2009-03-24 2010-09-30 University Of Chicago Slip chip device and methods
US8573259B2 (en) * 2009-03-25 2013-11-05 The Regents Of The University Of Michigan Modular microfluidic assembly block and system including the same
WO2010118427A1 (en) * 2009-04-10 2010-10-14 Canon U.S. Life Sciences, Inc. Fluid interface cartridge for a microfluidic chip
EP2251079A1 (en) * 2009-05-11 2010-11-17 Chemtrix B.V. A micro-fluidic system and the use thereof
GB2473868A (en) * 2009-09-28 2011-03-30 Invitrogen Dynal As Apparatus and method of automated processing of biological samples
BRPI1010169A2 (pt) * 2009-06-05 2016-03-29 Integenx Inc sistema que se ajusta dentro de um invólucro de não mais que 10 pés3, cartucho, artigo em forma legível por computador, método, sistema configurado para realizar um método, sistema óptico, instrumento e dispositivo.
KR20120125220A (ko) * 2009-07-20 2012-11-14 실로암 바이오사이언스, 아이엔씨. 마이크로유체 검정 플랫폼
WO2011028578A2 (en) * 2009-09-01 2011-03-10 Corsolutions, Llc Microfluidic interface
US8372657B2 (en) 2009-10-20 2013-02-12 Agency For Science, Technology, And Research Microfluidic system for detecting a biological entity in a sample
KR101141248B1 (ko) * 2009-10-22 2012-05-04 전남대학교산학협력단 공기방울 제거 및 유체 주입/제거를 위한 미세 유체칩용 소자
EP3514519B1 (en) * 2009-12-07 2022-02-09 Meso Scale Technologies, LLC. Assay cartridges
US9353342B2 (en) * 2010-01-21 2016-05-31 Emd Millipore Corporation Cell culture and gradient migration assay methods and devices
WO2011094605A1 (en) 2010-01-29 2011-08-04 Columbia University Microfluidic flow devices, methods and systems
CN102740976B (zh) * 2010-01-29 2016-04-20 精密公司 取样-应答微流体盒
US8994946B2 (en) * 2010-02-19 2015-03-31 Pacific Biosciences Of California, Inc. Integrated analytical system and method
EP2537053B1 (en) * 2010-02-19 2016-11-02 Pacific Biosciences of California, Inc. An analytical device comprising an optode array chip
BR112012026406B1 (pt) * 2010-04-16 2020-06-09 Opko Diagnostics Llc método de conduzir controle de qualidade para determinar anormalidades na operação de um sistema microfluídico
WO2011147421A1 (en) * 2010-05-27 2011-12-01 Danmarks Tekniske Universitet Chip connector
WO2011149829A1 (en) * 2010-05-27 2011-12-01 3M Innovative Properties Company Integrated systems and assemblies for sample processing
WO2011149853A1 (en) * 2010-05-27 2011-12-01 3M Innovative Properties Company Methods and articles for sample processing
US9132422B2 (en) * 2010-06-03 2015-09-15 Spinomix, S.A. Fluidic interfacing system and assembly
US8651642B2 (en) * 2010-10-22 2014-02-18 Hewlett-Packard Development Company, L.P. Fluid cartridge
US8657420B2 (en) * 2010-12-28 2014-02-25 Fujifilm Corporation Fluid recirculation in droplet ejection devices
CA2828110C (en) * 2011-02-28 2020-03-31 President And Fellows Of Harvard College Cell culture system
CN102114275B (zh) 2011-03-17 2012-10-17 浙江大学 类肝小叶生物反应器
US10526572B2 (en) * 2011-04-01 2020-01-07 EMD Millipore Corporaticn Cell culture and invasion assay method and system
FR2973720B1 (fr) * 2011-04-08 2016-02-26 Commissariat Energie Atomique Dispositif de connexion d'une carte microfluidique
JP2014514926A (ja) * 2011-04-12 2014-06-26 ミクロドイツ・ゲーエムベーハー 細胞培養装置
WO2012170562A2 (en) * 2011-06-06 2012-12-13 Corsolutions, Llc Fluidic interface
US10024826B2 (en) * 2011-08-22 2018-07-17 Waters Technologies Corporation Analysis of dried blood spot samples in a microfluidic system with dilution of extracted samples
WO2013130910A1 (en) * 2012-02-29 2013-09-06 Integenx Inc. Sample preparation, processing and analysis systems
US8894946B2 (en) 2011-10-21 2014-11-25 Integenx Inc. Sample preparation, processing and analysis systems
CN104284723B (zh) * 2011-11-14 2016-06-01 梅特勒-托利多索顿公司 用于微流控芯片的流体和电气接口
EP2785825B1 (en) * 2011-12-03 2021-04-21 EMD Millipore Corporation Microfluidic cell culture system
WO2013086486A1 (en) * 2011-12-09 2013-06-13 President And Fellows Of Harvard College Integrated human organ-on-chip microphysiological systems
HK1202270A1 (en) 2012-03-06 2015-09-25 Uab研究基金会 Three-dimesional, prevascularized, engineered tissue constructs, methods of making and methods of using the tissue constructs
US9533302B2 (en) * 2012-03-09 2017-01-03 Lexmark International, Inc. Fluid cartridge and system for dispensing fluid
US20130299003A1 (en) * 2012-05-09 2013-11-14 David J. Beebe Method And Device For Actuating Fluid Flow In A Microchannel
US9180449B2 (en) * 2012-06-12 2015-11-10 Hach Company Mobile water analysis
US9255245B2 (en) 2012-07-03 2016-02-09 Agilent Technologies, Inc. Sample probes and methods for sampling intracellular material
JP6302187B2 (ja) * 2012-08-13 2018-03-28 キヤノン株式会社 マイクロ流路チップおよびその製造方法
US20140161686A1 (en) * 2012-12-10 2014-06-12 Advanced Liquid Logic, Inc. System and method of dispensing liquids in a microfluidic device
EP2777499B1 (en) * 2013-03-15 2015-09-16 Ortho-Clinical Diagnostics Inc Rotatable fluid sample collection device
CN105026932B (zh) 2013-03-15 2017-06-13 西门子医疗保健诊断公司 微流控分配设备
CA2942908C (en) 2013-03-15 2023-08-15 Lariat Biosciences, Inc. Microfluidic methods for manipulating dna
US9416776B2 (en) 2013-03-15 2016-08-16 Siemens Healthcare Diagnostics Inc. Microfluidic distributing device
EP2969213B1 (en) * 2013-03-16 2022-11-02 Leslie Don ROBERTS Self-contained modular analytical cartridge and programmable reagent delivery system
DE102013006542B4 (de) * 2013-04-16 2017-03-23 Dräger Safety AG & Co. KGaA Messvorrichtung, Reaktionsträger und Messverfahren
WO2014210364A2 (en) 2013-06-26 2014-12-31 President And Fellows Of Harvard College Interconnect adaptor
PT3030645T (pt) 2013-08-08 2023-02-16 Illumina Inc Sistema de fluidos para entrega de reagente a uma célula de fluxo
JP6230103B2 (ja) * 2013-10-08 2017-11-15 国立研究開発法人産業技術総合研究所 細胞培養装置および細胞培養方法
US20160244713A1 (en) * 2013-10-24 2016-08-25 Hitachi, Ltd. Automated culture device
EP4113097A1 (en) * 2013-12-13 2023-01-04 Ventana Medical Systems, Inc. Automated processing systems and methods of thermally processing microscope slides
US20170080426A1 (en) * 2014-05-14 2017-03-23 University Of Limerick Device and method for testing compounds on living cells
GB2546424A (en) 2014-07-14 2017-07-19 Harvard College Systems and methods for improved performance of fluidic and microfluidic systems
US9593997B2 (en) * 2014-08-08 2017-03-14 Fluke Corporation Self-locking modular pressure controller/calibrator
EP3212757A4 (en) * 2014-10-27 2018-07-04 The Governing Council of the University of Toronto Microfluidic device for cell-based assays
US9861982B2 (en) * 2015-03-09 2018-01-09 Emd Millipore Corporation Connectors for pneumatic devices in microfluidic systems
WO2016171902A1 (en) * 2015-04-20 2016-10-27 Rush University Medical Center Chamber for imaging cells and method of use thereof
EP4026616B1 (en) * 2015-08-26 2024-12-11 Emulate, Inc. Perfusion manifold assembly
US10335788B2 (en) * 2016-07-12 2019-07-02 EMULATE, Inc. Removing bubbles in a microfluidic device
CN206868242U (zh) * 2017-04-01 2018-01-12 南京岚煜生物科技有限公司 基于主动控制液体流动的微流控芯片
CN111289762B (zh) * 2020-04-02 2024-11-15 厦门大学附属翔安医院 一种微流控芯片加样装置及测试方法

Similar Documents

Publication Publication Date Title
JP2021175416A5 (enExample)
CN203098881U (zh) 一种无外泄漏阀门
CA2582121A1 (en) Connector
RU2008137254A (ru) Устройство и способ освобождения набора емкостей от текучей среды и заполнения такого набора емкостей
SE7708337L (sv) Roterande ventil
SA522432416B1 (ar) تحسينات في صمامات تخزين مؤقت منزلقة أو مرتبطة بها وطرق لها
CN102748506B (zh) 电液先导控制开关阀组
CN111183318B (zh) 用于控制流体流动的阀、流体分配系统和用于测量差压的方法
CN102817877A (zh) 一种水压开关控制阀
MX367175B (es) Controlador de presion proporcional con montaje de valvula de aislamiento.
RU2675646C1 (ru) Клапан с низким коэффициентом трения
KR20170054890A (ko) 고온용 유체 제어 공압 밸브
CN204805595U (zh) 超低温双排压硬密封闸阀
CN216768385U (zh) 一种带双向密封双碟版蝶阀
CN205937280U (zh) 一种插装阀总成
CN108758020B (zh) 一种双通旋塞式阀门
KR200383974Y1 (ko) Y형 다이어프램 밸브
CA2476813A1 (en) High-pressure plug valve with replaceable inserts and method of refurbishing same
EA202191474A1 (ru) Клапанный узел
US3958598A (en) High pressure, 4-position, 5-way, pilot operated valve for corrosive media
CN221957914U (zh) 一种六联插装阀
CN216590001U (zh) 一种具有防卡顿结构的旋塞阀
JPH047408Y2 (enExample)
CN211231766U (zh) 高性能铜锌合金气动电磁阀座
CN103423241A (zh) 一体式逻辑流量阻断控制方法及其装置