JP2021020902A5 - - Google Patents

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JP2021020902A5
JP2021020902A5 JP2020159855A JP2020159855A JP2021020902A5 JP 2021020902 A5 JP2021020902 A5 JP 2021020902A5 JP 2020159855 A JP2020159855 A JP 2020159855A JP 2020159855 A JP2020159855 A JP 2020159855A JP 2021020902 A5 JP2021020902 A5 JP 2021020902A5
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Japan
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pyrrolidine
pyrazine
carboxamide
imidazole
ethyl
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JP2020159855A
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English (en)
Japanese (ja)
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JP7358317B2 (ja
JP2021020902A (ja
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Publication of JP2021020902A publication Critical patent/JP2021020902A/ja
Publication of JP2021020902A5 publication Critical patent/JP2021020902A5/ja
Priority to JP2022079226A priority Critical patent/JP2022107001A/ja
Priority to JP2023096042A priority patent/JP2023113917A/ja
Publication of JP7358317B2 publication Critical patent/JP7358317B2/ja
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Priority to JP2024041977A priority patent/JP2024073591A/ja
Priority to JP2025133176A priority patent/JP2025166112A/ja
Priority to JP2025133177A priority patent/JP2025166113A/ja
Priority to JP2025165233A priority patent/JP2026004431A/ja
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JP2020159855A 2015-10-16 2020-09-24 （３Ｓ，４Ｒ）－３－エチル－４－（３Ｈ－イミダゾ［１，２－ａ］ピロロ［２，３－ｅ］－ピラジン－８－イル）－Ｎ－（２，２，２－トリフルオロエチル）ピロリジン－１－カルボキサミドおよびそれの固体型の製造方法 Active JP7358317B2 (ja)

Priority Applications (6)

Application Number Priority Date Filing Date Title
JP2022079226A JP2022107001A (ja) 2015-10-16 2022-05-13 （３Ｓ，４Ｒ）－３－エチル－４－（３Ｈ－イミダゾ［１，２－ａ］ピロロ［２，３－ｅ］－ピラジン－８－イル）－Ｎ－（２，２，２－トリフルオロエチル）ピロリジン－１－カルボキサミドおよびそれの固体型の製造方法
JP2023096042A JP2023113917A (ja) 2015-10-16 2023-06-12 （３Ｓ，４Ｒ）－３－エチル－４－（３Ｈ－イミダゾ［１，２－ａ］ピロロ［２，３－ｅ］－ピラジン－８－イル）－Ｎ－（２，２，２－トリフルオロエチル）ピロリジン－１－カルボキサミドおよびそれの固体型の製造方法
JP2024041977A JP2024073591A (ja) 2015-10-16 2024-03-18 （３Ｓ，４Ｒ）－３－エチル－４－（３Ｈ－イミダゾ［１，２－ａ］ピロロ［２，３－ｅ］－ピラジン－８－イル）－Ｎ－（２，２，２－トリフルオロエチル）ピロリジン－１－カルボキサミドおよびそれの固体型の製造方法
JP2025133177A JP2025166113A (ja) 2015-10-16 2025-08-08 （３Ｓ，４Ｒ）－３－エチル－４－（３Ｈ－イミダゾ［１，２－ａ］ピロロ［２，３－ｅ］－ピラジン－８－イル）－Ｎ－（２，２，２－トリフルオロエチル）ピロリジン－１－カルボキサミドおよびそれの固体型の製造方法
JP2025133176A JP2025166112A (ja) 2015-10-16 2025-08-08 （３Ｓ，４Ｒ）－３－エチル－４－（３Ｈ－イミダゾ［１，２－ａ］ピロロ［２，３－ｅ］－ピラジン－８－イル）－Ｎ－（２，２，２－トリフルオロエチル）ピロリジン－１－カルボキサミドおよびそれの固体型の製造方法
JP2025165233A JP2026004431A (ja) 2015-10-16 2025-10-01 （３Ｓ，４Ｒ）－３－エチル－４－（３Ｈ－イミダゾ［１，２－ａ］ピロロ［２，３－ｅ］－ピラジン－８－イル）－Ｎ－（２，２，２－トリフルオロエチル）ピロリジン－１－カルボキサミドおよびそれの固体型の製造方法

Applications Claiming Priority (9)

Application Number Priority Date Filing Date Title
US201562242797P 2015-10-16 2015-10-16
US62/242,797 2015-10-16
US201562267672P 2015-12-15 2015-12-15
US62/267,672 2015-12-15
US201662301537P 2016-02-29 2016-02-29
US62/301,537 2016-02-29
US201662352380P 2016-06-20 2016-06-20
US62/352,380 2016-06-20
JP2018517576A JP6770775B2 (ja) 2015-10-16 2016-10-17 （３Ｓ，４Ｒ）−３−エチル−４−（３Ｈ−イミダゾ［１，２−ａ］ピロロ［２，３−ｅ］−ピラジン−８−イル）−Ｎ−（２，２，２−トリフルオロエチル）ピロリジン−１−カルボキサミドおよびそれの固体型の製造方法

Related Parent Applications (1)

Application Number Title Priority Date Filing Date
JP2018517576A Division JP6770775B2 (ja) 2015-10-16 2016-10-17 （３Ｓ，４Ｒ）−３−エチル−４−（３Ｈ−イミダゾ［１，２−ａ］ピロロ［２，３−ｅ］−ピラジン−８−イル）−Ｎ−（２，２，２−トリフルオロエチル）ピロリジン−１−カルボキサミドおよびそれの固体型の製造方法

Related Child Applications (2)

Application Number Title Priority Date Filing Date
JP2022079226A Division JP2022107001A (ja) 2015-10-16 2022-05-13 （３Ｓ，４Ｒ）－３－エチル－４－（３Ｈ－イミダゾ［１，２－ａ］ピロロ［２，３－ｅ］－ピラジン－８－イル）－Ｎ－（２，２，２－トリフルオロエチル）ピロリジン－１－カルボキサミドおよびそれの固体型の製造方法
JP2023096042A Division JP2023113917A (ja) 2015-10-16 2023-06-12 （３Ｓ，４Ｒ）－３－エチル－４－（３Ｈ－イミダゾ［１，２－ａ］ピロロ［２，３－ｅ］－ピラジン－８－イル）－Ｎ－（２，２，２－トリフルオロエチル）ピロリジン－１－カルボキサミドおよびそれの固体型の製造方法

Publications (3)

Publication Number Publication Date
JP2021020902A JP2021020902A (ja) 2021-02-18
JP2021020902A5 true JP2021020902A5 (enExample) 2021-11-25
JP7358317B2 JP7358317B2 (ja) 2023-10-10

Family

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Family Applications (8)

Application Number Title Priority Date Filing Date
JP2018517576A Active JP6770775B2 (ja) 2015-10-16 2016-10-17 （３Ｓ，４Ｒ）−３−エチル−４−（３Ｈ−イミダゾ［１，２−ａ］ピロロ［２，３−ｅ］−ピラジン−８−イル）−Ｎ−（２，２，２−トリフルオロエチル）ピロリジン−１−カルボキサミドおよびそれの固体型の製造方法
JP2020159855A Active JP7358317B2 (ja) 2015-10-16 2020-09-24 （３Ｓ，４Ｒ）－３－エチル－４－（３Ｈ－イミダゾ［１，２－ａ］ピロロ［２，３－ｅ］－ピラジン－８－イル）－Ｎ－（２，２，２－トリフルオロエチル）ピロリジン－１－カルボキサミドおよびそれの固体型の製造方法
JP2022079226A Pending JP2022107001A (ja) 2015-10-16 2022-05-13 （３Ｓ，４Ｒ）－３－エチル－４－（３Ｈ－イミダゾ［１，２－ａ］ピロロ［２，３－ｅ］－ピラジン－８－イル）－Ｎ－（２，２，２－トリフルオロエチル）ピロリジン－１－カルボキサミドおよびそれの固体型の製造方法
JP2023096042A Pending JP2023113917A (ja) 2015-10-16 2023-06-12 （３Ｓ，４Ｒ）－３－エチル－４－（３Ｈ－イミダゾ［１，２－ａ］ピロロ［２，３－ｅ］－ピラジン－８－イル）－Ｎ－（２，２，２－トリフルオロエチル）ピロリジン－１－カルボキサミドおよびそれの固体型の製造方法
JP2024041977A Pending JP2024073591A (ja) 2015-10-16 2024-03-18 （３Ｓ，４Ｒ）－３－エチル－４－（３Ｈ－イミダゾ［１，２－ａ］ピロロ［２，３－ｅ］－ピラジン－８－イル）－Ｎ－（２，２，２－トリフルオロエチル）ピロリジン－１－カルボキサミドおよびそれの固体型の製造方法
JP2025133177A Pending JP2025166113A (ja) 2015-10-16 2025-08-08 （３Ｓ，４Ｒ）－３－エチル－４－（３Ｈ－イミダゾ［１，２－ａ］ピロロ［２，３－ｅ］－ピラジン－８－イル）－Ｎ－（２，２，２－トリフルオロエチル）ピロリジン－１－カルボキサミドおよびそれの固体型の製造方法
JP2025133176A Pending JP2025166112A (ja) 2015-10-16 2025-08-08 （３Ｓ，４Ｒ）－３－エチル－４－（３Ｈ－イミダゾ［１，２－ａ］ピロロ［２，３－ｅ］－ピラジン－８－イル）－Ｎ－（２，２，２－トリフルオロエチル）ピロリジン－１－カルボキサミドおよびそれの固体型の製造方法
JP2025165233A Pending JP2026004431A (ja) 2015-10-16 2025-10-01 （３Ｓ，４Ｒ）－３－エチル－４－（３Ｈ－イミダゾ［１，２－ａ］ピロロ［２，３－ｅ］－ピラジン－８－イル）－Ｎ－（２，２，２－トリフルオロエチル）ピロリジン－１－カルボキサミドおよびそれの固体型の製造方法

Family Applications Before (1)

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JP2018517576A Active JP6770775B2 (ja) 2015-10-16 2016-10-17 （３Ｓ，４Ｒ）−３−エチル−４−（３Ｈ−イミダゾ［１，２−ａ］ピロロ［２，３−ｅ］−ピラジン−８−イル）−Ｎ−（２，２，２−トリフルオロエチル）ピロリジン−１−カルボキサミドおよびそれの固体型の製造方法

Family Applications After (6)

Application Number Title Priority Date Filing Date
JP2022079226A Pending JP2022107001A (ja) 2015-10-16 2022-05-13 （３Ｓ，４Ｒ）－３－エチル－４－（３Ｈ－イミダゾ［１，２－ａ］ピロロ［２，３－ｅ］－ピラジン－８－イル）－Ｎ－（２，２，２－トリフルオロエチル）ピロリジン－１－カルボキサミドおよびそれの固体型の製造方法
JP2023096042A Pending JP2023113917A (ja) 2015-10-16 2023-06-12 （３Ｓ，４Ｒ）－３－エチル－４－（３Ｈ－イミダゾ［１，２－ａ］ピロロ［２，３－ｅ］－ピラジン－８－イル）－Ｎ－（２，２，２－トリフルオロエチル）ピロリジン－１－カルボキサミドおよびそれの固体型の製造方法
JP2024041977A Pending JP2024073591A (ja) 2015-10-16 2024-03-18 （３Ｓ，４Ｒ）－３－エチル－４－（３Ｈ－イミダゾ［１，２－ａ］ピロロ［２，３－ｅ］－ピラジン－８－イル）－Ｎ－（２，２，２－トリフルオロエチル）ピロリジン－１－カルボキサミドおよびそれの固体型の製造方法
JP2025133177A Pending JP2025166113A (ja) 2015-10-16 2025-08-08 （３Ｓ，４Ｒ）－３－エチル－４－（３Ｈ－イミダゾ［１，２－ａ］ピロロ［２，３－ｅ］－ピラジン－８－イル）－Ｎ－（２，２，２－トリフルオロエチル）ピロリジン－１－カルボキサミドおよびそれの固体型の製造方法
JP2025133176A Pending JP2025166112A (ja) 2015-10-16 2025-08-08 （３Ｓ，４Ｒ）－３－エチル－４－（３Ｈ－イミダゾ［１，２－ａ］ピロロ［２，３－ｅ］－ピラジン－８－イル）－Ｎ－（２，２，２－トリフルオロエチル）ピロリジン－１－カルボキサミドおよびそれの固体型の製造方法
JP2025165233A Pending JP2026004431A (ja) 2015-10-16 2025-10-01 （３Ｓ，４Ｒ）－３－エチル－４－（３Ｈ－イミダゾ［１，２－ａ］ピロロ［２，３－ｅ］－ピラジン－８－イル）－Ｎ－（２，２，２－トリフルオロエチル）ピロリジン－１－カルボキサミドおよびそれの固体型の製造方法

Country Status (13)

Country Link
US (39) US20170129902A1 (enExample)
EP (5) EP4706768A2 (enExample)
JP (8) JP6770775B2 (enExample)
KR (2) KR102753815B1 (enExample)
CN (8) CN120289468A (enExample)
AU (5) AU2016340167B2 (enExample)
BR (1) BR122022024925B1 (enExample)
CA (9) CA3251507C (enExample)
IL (3) IL314468A (enExample)
MX (2) MX387822B (enExample)
RU (1) RU2018117889A (enExample)
SG (8) SG10201913990RA (enExample)
WO (1) WO2017066775A1 (enExample)

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