JP2020534788A5 - - Google Patents
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- JP2020534788A5 JP2020534788A5 JP2019562303A JP2019562303A JP2020534788A5 JP 2020534788 A5 JP2020534788 A5 JP 2020534788A5 JP 2019562303 A JP2019562303 A JP 2019562303A JP 2019562303 A JP2019562303 A JP 2019562303A JP 2020534788 A5 JP2020534788 A5 JP 2020534788A5
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Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201762551133P | 2017-08-28 | 2017-08-28 | |
| US62/551,133 | 2017-08-28 | ||
| PCT/US2018/047561 WO2019046069A1 (en) | 2017-08-28 | 2018-08-22 | ADENO-ASSOCIATED VIRUS CAPSID VARIANTS AND METHODS OF USE |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JP2020534788A JP2020534788A (ja) | 2020-12-03 |
| JP2020534788A5 true JP2020534788A5 (enExample) | 2021-09-30 |
Family
ID=65525930
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2019562303A Withdrawn JP2020534788A (ja) | 2017-08-28 | 2018-08-22 | アデノ随伴ウイルスカプシド変異体及びその使用方法 |
Country Status (10)
| Country | Link |
|---|---|
| US (1) | US11680249B2 (enExample) |
| EP (1) | EP3676373A4 (enExample) |
| JP (1) | JP2020534788A (enExample) |
| KR (1) | KR20200039617A (enExample) |
| CN (1) | CN110709511A (enExample) |
| AU (1) | AU2018324477A1 (enExample) |
| BR (1) | BR112020003571A2 (enExample) |
| CA (1) | CA3059995A1 (enExample) |
| MX (1) | MX2020001997A (enExample) |
| WO (1) | WO2019046069A1 (enExample) |
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| Publication number | Priority date | Publication date | Assignee | Title |
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| CN105755044A (zh) | 2011-04-22 | 2016-07-13 | 加利福尼亚大学董事会 | 具有变异衣壳的腺相关病毒病毒体及其使用方法 |
| EP3003391B1 (en) | 2013-05-31 | 2021-09-22 | The Regents of The University of California | Adeno-associated virus variants and methods of use thereof |
| EP3800191B1 (en) | 2014-03-17 | 2025-08-20 | Adverum Biotechnologies, Inc. | Compositions and methods for enhanced gene expression in cone cells |
| EP3151866B1 (en) | 2014-06-09 | 2023-03-08 | Voyager Therapeutics, Inc. | Chimeric capsids |
| AU2017302013B2 (en) | 2016-07-29 | 2022-05-26 | The Regents Of The University Of California | Adeno-associated virus virions with variant capsid and methods of use thereof |
| CA3040179A1 (en) | 2016-10-19 | 2018-04-26 | Adverum Biotechnologies, Inc. | Modified aav capsids and uses thereof |
| CA3053154A1 (en) * | 2017-06-30 | 2019-01-03 | The Regents Of The University Of California | Adeno-associated virus virions with variant capsids and methods of use thereof |
| EP3808849A1 (en) | 2017-08-03 | 2021-04-21 | Voyager Therapeutics, Inc. | Compositions and methods for delivery of aav |
| JP2020534788A (ja) | 2017-08-28 | 2020-12-03 | ザ リージェンツ オブ ザ ユニバーシティ オブ カリフォルニア | アデノ随伴ウイルスカプシド変異体及びその使用方法 |
| AU2018338728B2 (en) | 2017-09-29 | 2025-01-02 | Centre National De La Recherche Scientifique (Cnrs) | Rescue of central and peripheral neurological phenotype of Friedreich's Ataxia by intravenous delivery |
| WO2019200016A1 (en) | 2018-04-10 | 2019-10-17 | President And Fellows Of Harvard College | Aav vectors encoding clarin-1 or gjb2 and uses thereof |
| CN113966399A (zh) | 2018-09-26 | 2022-01-21 | 加州理工学院 | 用于靶向基因疗法的腺相关病毒组合物 |
| EP3856762A1 (en) | 2018-09-28 | 2021-08-04 | Voyager Therapeutics, Inc. | Frataxin expression constructs having engineered promoters and methods of use thereof |
| KR102934700B1 (ko) * | 2019-03-28 | 2026-03-09 | 더 제너럴 하스피탈 코포레이션 | 트랜스진 발현을 위한 조작된 아데노-연관 (aav) 벡터 |
| TW202102526A (zh) * | 2019-04-04 | 2021-01-16 | 美商銳進科斯生物股份有限公司 | 重組腺相關病毒及其用途 |
| JP2022526018A (ja) * | 2019-04-11 | 2022-05-20 | カリフォルニア インスティテュート オブ テクノロジー | 脳内への特異性が増強されたウイルス組成物 |
| CA3140049A1 (en) * | 2019-05-14 | 2020-11-19 | Duke University | Compositions and methods for the treatment of atpase-mediated diseases |
| US12552838B2 (en) | 2020-04-20 | 2026-02-17 | Tenaya Therapeutics, Inc. | Adeno-associated virus with engineered capsid |
| CN116390934A (zh) * | 2020-05-26 | 2023-07-04 | 塑造治疗公司 | 功能性aav衣壳的高通量工程化 |
| US12031147B2 (en) | 2020-05-29 | 2024-07-09 | The Regents Of The University Of California | Adeno-associated virus virions with variant capsids and methods of use thereof |
| US12129287B2 (en) | 2020-09-14 | 2024-10-29 | President And Fellows Of Harvard College | Recombinant adeno associated virus encoding clarin-1 and uses thereof |
| CN113754727B (zh) * | 2020-09-30 | 2022-07-12 | 广州派真生物技术有限公司 | 腺相关病毒突变体及其应用 |
| EP4229204A1 (en) | 2020-10-15 | 2023-08-23 | F. Hoffmann-La Roche AG | Nucleic acid constructs for simultaneous gene activation |
| CN113025658B (zh) * | 2021-03-10 | 2022-04-22 | 华侨大学 | 一种神经干细胞特异性基因的递送载体及其应用 |
| CN113121651B (zh) * | 2021-04-19 | 2023-11-17 | 信念医药科技(上海)有限公司 | 低中和抗体腺相关病毒衣壳蛋白 |
| WO2023010120A2 (en) * | 2021-07-30 | 2023-02-02 | University Of Florida Research Foundation, Incorporated | Engineering aav vectors with improved cns targeting |
| CN114057840B (zh) * | 2021-10-14 | 2022-09-20 | 和元生物技术（上海）股份有限公司 | 包含变异的aav9衣壳蛋白的重组腺相关病毒颗粒 |
| CN119095866A (zh) * | 2022-02-22 | 2024-12-06 | 北卡罗来纳大学查佩尔希尔分校 | 嵌合神经向性aav衣壳 |
| WO2024017387A1 (en) | 2022-07-22 | 2024-01-25 | Shanghai Vitalgen Biopharma Co., Ltd. | Novel aav capsids for targeting nervous system and uses thereof |
| CN116789739B (zh) * | 2022-12-08 | 2024-01-26 | 广州派真生物技术有限公司 | 腺相关病毒突变体及其应用 |
| CN117012275A (zh) * | 2023-08-11 | 2023-11-07 | 瑞诺元(苏州)生物科技有限公司 | 一种腺相关病毒测序数据的分析方法及系统 |
| WO2025147741A1 (en) * | 2024-01-11 | 2025-07-17 | Children's Medical Research Institute | Aav capsids and vectors for transduction of cells |
| KR20260014488A (ko) * | 2024-07-22 | 2026-01-30 | 한국생명공학연구원 | 변이체 캡시드를 포함하는 아데노-연관 바이러스 및 이의 용도 |
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2018
- 2018-08-22 JP JP2019562303A patent/JP2020534788A/ja not_active Withdrawn
- 2018-08-22 US US16/500,706 patent/US11680249B2/en active Active
- 2018-08-22 KR KR1020197035110A patent/KR20200039617A/ko not_active Withdrawn
- 2018-08-22 BR BR112020003571-8A patent/BR112020003571A2/pt not_active IP Right Cessation
- 2018-08-22 WO PCT/US2018/047561 patent/WO2019046069A1/en not_active Ceased
- 2018-08-22 CN CN201880035665.2A patent/CN110709511A/zh active Pending
- 2018-08-22 AU AU2018324477A patent/AU2018324477A1/en not_active Abandoned
- 2018-08-22 CA CA3059995A patent/CA3059995A1/en active Pending
- 2018-08-22 MX MX2020001997A patent/MX2020001997A/es unknown
- 2018-08-22 EP EP18850221.5A patent/EP3676373A4/en not_active Withdrawn
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