JP2020521440A5 - - Google Patents
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- Publication number
- JP2020521440A5 JP2020521440A5 JP2019559727A JP2019559727A JP2020521440A5 JP 2020521440 A5 JP2020521440 A5 JP 2020521440A5 JP 2019559727 A JP2019559727 A JP 2019559727A JP 2019559727 A JP2019559727 A JP 2019559727A JP 2020521440 A5 JP2020521440 A5 JP 2020521440A5
- Authority
- JP
- Japan
- Prior art keywords
- exon
- ros1
- alk
- composition according
- fusion gene
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP2023206878A JP2024019433A (ja) | 2017-05-31 | 2023-12-07 | Ａｌｋ、ｒｅｔ、およびｒｏｓ融合の多重ｐｃｒ検出 |
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201762513226P | 2017-05-31 | 2017-05-31 | |
| US62/513,226 | 2017-05-31 | ||
| PCT/EP2018/064172 WO2018220004A1 (en) | 2017-05-31 | 2018-05-30 | Multiplex pcr detection of alk, ret, and ros fusions |
Related Child Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2023206878A Division JP2024019433A (ja) | 2017-05-31 | 2023-12-07 | Ａｌｋ、ｒｅｔ、およびｒｏｓ融合の多重ｐｃｒ検出 |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JP2020521440A JP2020521440A (ja) | 2020-07-27 |
| JP2020521440A5 true JP2020521440A5 (enExample) | 2021-07-26 |
Family
ID=62567625
Family Applications (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2019559727A Pending JP2020521440A (ja) | 2017-05-31 | 2018-05-30 | Ａｌｋ、ｒｅｔ、およびｒｏｓ融合の多重ｐｃｒ検出 |
| JP2023206878A Pending JP2024019433A (ja) | 2017-05-31 | 2023-12-07 | Ａｌｋ、ｒｅｔ、およびｒｏｓ融合の多重ｐｃｒ検出 |
Family Applications After (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2023206878A Pending JP2024019433A (ja) | 2017-05-31 | 2023-12-07 | Ａｌｋ、ｒｅｔ、およびｒｏｓ融合の多重ｐｃｒ検出 |
Country Status (8)
| Country | Link |
|---|---|
| US (2) | US11505830B2 (enExample) |
| EP (1) | EP3631011B1 (enExample) |
| JP (2) | JP2020521440A (enExample) |
| CN (1) | CN110691852A (enExample) |
| AU (1) | AU2018277210B2 (enExample) |
| CA (1) | CA3059119C (enExample) |
| ES (1) | ES2883934T3 (enExample) |
| WO (1) | WO2018220004A1 (enExample) |
Families Citing this family (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP3631011B1 (en) | 2017-05-31 | 2021-06-23 | Roche Diagnostics GmbH | Multiplex pcr detection of alk, ret, and ros fusions |
| CN109837275B (zh) * | 2019-01-08 | 2022-09-06 | 大连医科大学附属第二医院 | 一种融合基因阳性对照标准品的制备方法 |
| CN111718994A (zh) * | 2019-03-22 | 2020-09-29 | 广州金域医学检验中心有限公司 | 肿瘤融合基因靶向检测探针、试剂盒及应用 |
| CN110964830A (zh) * | 2019-12-31 | 2020-04-07 | 中山大学达安基因股份有限公司 | 多重检测ros1基因突变的试剂盒及方法 |
| CN112029857B (zh) * | 2020-08-14 | 2026-03-24 | 上海真固生物科技有限公司 | 一种引物组合物及用于融合基因检测的试剂 |
| CN115466788B (zh) * | 2022-06-28 | 2026-02-10 | 湖南圣洲生物科技有限公司 | 引物探针组合、试剂盒及其检测人alk、ros1基因融合的方法 |
| CN117144016A (zh) * | 2023-10-27 | 2023-12-01 | 神州医疗科技股份有限公司 | 一种用于外周血循环肿瘤rna中检测ret融合基因的引物探针、试剂盒及检测系统 |
Family Cites Families (20)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5455170A (en) | 1986-08-22 | 1995-10-03 | Hoffmann-La Roche Inc. | Mutated thermostable nucleic acid polymerase enzyme from Thermus species Z05 |
| AU762754B2 (en) * | 1999-02-18 | 2003-07-03 | Regents Of The University Of California, The | Salicylamide-lanthanide complexes for use as luminescent markers |
| CA2405687A1 (en) * | 2000-04-05 | 2001-10-18 | Molecular Staging, Inc. | Process for allele discrimation utilizing primer extension |
| US7385043B1 (en) | 2003-04-30 | 2008-06-10 | The Public Health Research Institute Of The City Of New York, Inc. | Homogeneous multiplex screening assays and kits |
| PL2450437T3 (pl) * | 2006-04-14 | 2017-12-29 | Cell Signaling Technology Inc | Defekty genu i zmutowana kinaza ALK w ludzkich guzach litych |
| WO2008127248A1 (en) * | 2007-04-13 | 2008-10-23 | Cell Signaling Technology, Inc. | Gene defects and mutant alk kinase in human solid tumors |
| EP2775300A3 (en) * | 2009-08-28 | 2015-04-01 | Asuragen, INC. | miRNA Biomarkers of Lung Disease |
| JP5861244B2 (ja) | 2010-06-22 | 2016-02-16 | 公益財団法人がん研究会 | 新規ｒｏｓ１融合体の検出法 |
| JPWO2012014795A1 (ja) * | 2010-07-26 | 2013-09-12 | アステラス製薬株式会社 | 新規ｒｅｔ融合体の検出法 |
| US20130059762A1 (en) * | 2011-04-28 | 2013-03-07 | Life Technologies Corporation | Methods and compositions for multiplex pcr |
| US20130237442A1 (en) * | 2012-03-07 | 2013-09-12 | University Of Miami | Methods and Compositions for Diagnosis of Non-Viable Early Pregnancy |
| CN105102635B (zh) * | 2013-03-15 | 2020-09-25 | 生命技术公司 | 肺癌的分类和可行性指数 |
| CA2902167A1 (en) | 2013-03-15 | 2014-09-25 | Abbott Molecular Inc. | Method for amplification and assay of rna fusion gene variants, method of distinguishing same and related primers, probes, and kits |
| US10072298B2 (en) | 2013-04-17 | 2018-09-11 | Life Technologies Corporation | Gene fusions and gene variants associated with cancer |
| WO2015148494A1 (en) | 2014-03-25 | 2015-10-01 | Quest Diagnostics Investments Incorporated | Detection of gene fusions by intragenic differential expression (ide) using average cycle thresholds |
| CN106414768B (zh) | 2014-03-27 | 2020-05-29 | 生命技术公司 | 与癌症相关的基因融合体和基因变异体 |
| JP6696908B2 (ja) * | 2014-04-25 | 2020-05-20 | エグゼリクシス， インコーポレイテッド | 肺腺癌の治療方法 |
| CN104818320B (zh) * | 2014-12-03 | 2018-02-06 | 厦门艾德生物医药科技有限公司 | 一次性检测肺癌多重基因的引物、探针、检测体系和试剂盒 |
| JP6856544B2 (ja) * | 2015-04-17 | 2021-04-07 | エフ．ホフマン−ラ ロシュ アーゲーＦ． Ｈｏｆｆｍａｎｎ−Ｌａ Ｒｏｃｈｅ Ａｋｔｉｅｎｇｅｓｅｌｌｓｃｈａｆｔ | 遺伝子融合体を検出するための多重ｐｃｒ |
| EP3631011B1 (en) | 2017-05-31 | 2021-06-23 | Roche Diagnostics GmbH | Multiplex pcr detection of alk, ret, and ros fusions |
-
2018
- 2018-05-30 EP EP18730279.9A patent/EP3631011B1/en not_active Revoked
- 2018-05-30 ES ES18730279T patent/ES2883934T3/es active Active
- 2018-05-30 JP JP2019559727A patent/JP2020521440A/ja active Pending
- 2018-05-30 CA CA3059119A patent/CA3059119C/en active Active
- 2018-05-30 WO PCT/EP2018/064172 patent/WO2018220004A1/en not_active Ceased
- 2018-05-30 AU AU2018277210A patent/AU2018277210B2/en active Active
- 2018-05-30 CN CN201880035309.0A patent/CN110691852A/zh active Pending
- 2018-05-30 US US15/993,375 patent/US11505830B2/en active Active
-
2022
- 2022-10-06 US US17/961,200 patent/US20230121541A1/en active Pending
-
2023
- 2023-12-07 JP JP2023206878A patent/JP2024019433A/ja active Pending
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