JP2020513790A5 - - Google Patents

Download PDF

Info

Publication number
JP2020513790A5
JP2020513790A5 JP2019542552A JP2019542552A JP2020513790A5 JP 2020513790 A5 JP2020513790 A5 JP 2020513790A5 JP 2019542552 A JP2019542552 A JP 2019542552A JP 2019542552 A JP2019542552 A JP 2019542552A JP 2020513790 A5 JP2020513790 A5 JP 2020513790A5
Authority
JP
Japan
Prior art keywords
genetically engineered
engineered microbial
microbial cell
tydc
synthase
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
JP2019542552A
Other languages
English (en)
Japanese (ja)
Other versions
JP2020513790A (ja
Filing date
Publication date
Application filed filed Critical
Priority claimed from PCT/US2018/017127 external-priority patent/WO2018203947A2/en
Publication of JP2020513790A publication Critical patent/JP2020513790A/ja
Publication of JP2020513790A5 publication Critical patent/JP2020513790A5/ja
Pending legal-status Critical Current

Links

JP2019542552A 2017-02-06 2018-02-06 発酵によりチラミンを生成させるための遺伝子操作型生合成経路 Pending JP2020513790A (ja)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US201762455428P 2017-02-06 2017-02-06
US62/455,428 2017-02-06
PCT/US2018/017127 WO2018203947A2 (en) 2017-02-06 2018-02-06 Engineered biosynthetic pathways for production of tyramine by fermentation

Publications (2)

Publication Number Publication Date
JP2020513790A JP2020513790A (ja) 2020-05-21
JP2020513790A5 true JP2020513790A5 (https=) 2021-03-18

Family

ID=63294411

Family Applications (1)

Application Number Title Priority Date Filing Date
JP2019542552A Pending JP2020513790A (ja) 2017-02-06 2018-02-06 発酵によりチラミンを生成させるための遺伝子操作型生合成経路

Country Status (7)

Country Link
US (1) US11028416B2 (https=)
EP (1) EP3577220A2 (https=)
JP (1) JP2020513790A (https=)
KR (1) KR20190120238A (https=)
CN (1) CN110494560A (https=)
CA (1) CA3052635A1 (https=)
WO (1) WO2018203947A2 (https=)

Families Citing this family (17)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN112410379B (zh) 2013-11-04 2024-12-31 小利兰·斯坦福大学托管委员会 产生苄基异喹啉生物碱(bia)前体的微生物以及制备和使用所述前体的方法
WO2016183023A1 (en) 2015-05-08 2016-11-17 The Board Of Trustees Of The Leland Stanford Junior University Methods of producing epimerases and benzylisoquinoline alkaloids
WO2018203947A2 (en) 2017-02-06 2018-11-08 Zymergen Inc. Engineered biosynthetic pathways for production of tyramine by fermentation
CA3087269A1 (en) 2018-01-10 2019-07-18 Brightseed, Inc. Method for modulating metabolism
EP3656857A1 (en) * 2018-11-21 2020-05-27 Danmarks Tekniske Universitet Utilization of phosphoketolase for production of aromatic amino acid derived products
CN113784758B (zh) 2019-03-08 2025-03-07 小利兰·斯坦福大学托管委员会 产生莨菪烷生物碱(ta)的非植物宿主细胞及其制备和使用方法
WO2020232027A1 (en) * 2019-05-13 2020-11-19 Zymergen Inc. Stabilization of amines with sulfur compounds
CA3158769A1 (en) * 2019-10-25 2021-04-29 Brightseed, Inc. Recombinant cell, extract, consumable product and method for production of bioactive plant metabolite
CN116368233A (zh) * 2020-08-20 2023-06-30 齐默尔根公司 通过发酵生产4-氨基苯乙胺的工程化生物合成途径
CN113174375B (zh) * 2021-04-23 2022-11-04 天津大学 Aro3蛋白突变体及其应用
WO2022245340A1 (en) * 2021-05-18 2022-11-24 Zymergen Inc. Engineered biosynthetic pathways for production of deoxyhydrochorismic acid by fermentation
CN113684165B (zh) * 2021-08-12 2023-07-25 江南大学 一种重组谷氨酸棒杆菌及其在生产l-谷氨酰胺中的应用
EP4198123A1 (de) * 2021-12-17 2023-06-21 Covestro Deutschland AG Besonders geeignete 3-desoxyarabinoheptulosanat-7-phosphat-synthase zur fermentativen herstellung von ortho-aminobenzoesäure
CN116083387B (zh) * 2022-12-29 2025-09-02 华熙生物科技股份有限公司 酶、生产红景天苷的菌株及生产方法
CN116042553B (zh) * 2022-12-29 2025-08-26 浙江工业大学 甘油醛-3-磷酸脱氢酶突变体及在提高o-琥珀酰-l-高丝氨酸产量中的应用
CN117736960B (zh) * 2024-02-21 2024-05-07 滨州医学院 一种小白链霉菌基因工程菌及其应用
CN119144595B (zh) * 2024-11-13 2025-02-14 中国科学院微生物研究所 一种酪氨酸脱羧酶突变体及其在发酵合成3-氨基-1-丙醇中的应用

Family Cites Families (39)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE3128411A1 (de) 1980-07-18 1983-09-15 Unisearch Ltd., 2033 Kensington, New South Wales Kulturstamm-mutante von esccherichia coli sowie verfahren zur herstellung von phenylalanin
EP0077196A3 (en) 1981-10-09 1984-06-06 Genex Corporation Aromatic amino acid-producing microorganisms
JPH07108228B2 (ja) 1990-10-15 1995-11-22 味の素株式会社 温度感受性プラスミド
DK0782621T3 (da) 1994-09-16 2006-07-03 Texas A & M Univ Sys Mikroorganismer samt fremgangsmåde til overproduktion af DAHP ved hjælp af klonet PPS-gen
US6210937B1 (en) 1997-04-22 2001-04-03 Bechtel Bwxt Idaho, Llc Development of genetically engineered bacteria for production of selected aromatic compounds
US6297055B1 (en) 1998-09-08 2001-10-02 E. I. Du Pont De Nemours And Company Amino acid decarboxylases
US6600077B1 (en) 1999-01-29 2003-07-29 Board Of Trustees Operating Michigan State University Biocatalytic synthesis of quinic acid and conversion to hydroquinone
WO2000073484A1 (en) 1999-05-28 2000-12-07 University Of North Texas Health Science Center At Fort Worth A global regulator used to enhance the synthesis of aromatic substances
US20050089974A1 (en) 2000-10-27 2005-04-28 Townsend Craig A. Fermentative production of d-hydroxyphenylglycine and d-phenylglycine
RU2229514C2 (ru) 2000-11-13 2004-05-27 Закрытое акционерное общество "Научно-исследовательский институт "Аджиномото-Генетика" 3-дезокси-d-арабиногептулозонат-7-фосфатсинтаза и фрагмент днк, кодирующий 3-дезокси-d-арабиногептулозонат-7-фосфатсинтазу из methylophilus methylotrophus
KR101148255B1 (ko) 2002-10-04 2012-08-08 다니스코 유에스 인크. 고수율을 갖는 1,3-프로판디올의 생물학적 제조 방법
US8206955B2 (en) 2003-10-21 2012-06-26 Cargill, Incorporated Production of monatin and monatin precursors
CN1280417C (zh) * 2004-11-01 2006-10-18 清华大学 一种人酪氨酸酶表达载体及其应用
WO2007118682A1 (en) * 2006-04-13 2007-10-25 Dsm Ip Assets B.V. Process for the preparation of enantiomeri cally enriched beta-amino alcohols starting from glycine and an aldehyde in the presence of a threonine aldolase and a decarboxylase
WO2007140339A2 (en) 2006-05-26 2007-12-06 Amyris Biotechnologies, Inc. Production of isoprenoids
US7700328B2 (en) 2006-06-07 2010-04-20 E.I. Du Pont De Nemours And Company Method for producing an L-tyrosine over-producing bacterial strain
US8975063B2 (en) 2006-10-19 2015-03-10 California Institute Of Technology Compositions and methods for producing benzylisoquinoline alkaloids
US20080102499A1 (en) 2006-10-27 2008-05-01 Lori Jean Templeton Method of enhancing L-tyrosine production in recombinant bacteria
US20100047887A1 (en) 2006-11-27 2010-02-25 Jihane Achkar Method for preparing hydroxytyrosol
WO2009046370A2 (en) 2007-10-04 2009-04-09 Bio Architecture Lab, Inc. Biofuel production
CN105368764B (zh) 2007-12-13 2019-03-12 丹尼斯科美国公司 用于生产异戊二烯的组合物和方法
US20110045563A1 (en) 2008-02-06 2011-02-24 The Regents Of The University Of California Short chain volatile isoprene hydrocarbon production using the mevalonic acid pathway in genetically engineered yeast and fungi
WO2009132220A2 (en) 2008-04-23 2009-10-29 Danisco Us Inc. Isoprene synthase variants for improved microbial production of isoprene
US7632995B2 (en) 2008-05-09 2009-12-15 Monsanto Technology Llc Plants and seeds of hybrid corn variety CH852179
MX318543B (es) 2008-07-02 2014-03-18 Danisco Us Inc Composiciones y metodos para producir isopreno libre de hidrocarburos de c5 bajo condicion de desacoplamiento y/o intervalos de operacion seguros.
DE102008040352A1 (de) 2008-07-11 2010-01-14 Evonik Degussa Gmbh Verfahren zur Herstellung von L-Tryptophan unter Verwendung von verbesserten Stämmen der Familie Enterobacteriaceae
US20100297749A1 (en) 2009-04-21 2010-11-25 Sapphire Energy, Inc. Methods and systems for biofuel production
US20120252054A1 (en) 2009-09-15 2012-10-04 Sapphire Energy Inc System for transformation of the chloroplast genome of scenedesmus sp. and dunaliella sp.
KR20180014240A (ko) 2009-10-23 2018-02-07 게노마티카 인코포레이티드 아닐린의 제조를 위한 미생물
WO2012135389A2 (en) 2011-03-28 2012-10-04 The Regents Of The University Of California Host cells and methods for oxidizing aromatic amino acids
ES2663445T3 (es) 2012-01-30 2018-04-12 Myriant Corporation Producción de ácido mucónico a partir de microorganismos modificados genéticamente
US9234203B2 (en) 2012-05-21 2016-01-12 Cathay Industrial Biotech Ltd. Stabilized recombinant expression plasmid vector in hafnia alvei and applications thereof
EP3241902B1 (en) 2012-05-25 2018-02-28 The Regents of The University of California Methods and compositions for rna-directed target dna modification and for rna-directed modulation of transcription
MX374090B (es) 2013-03-14 2025-03-05 Caribou Biosciences Inc Composiciones y métodos de ácidos nucleicos dirigidos al ácido nucleico.
CN112410379B (zh) 2013-11-04 2024-12-31 小利兰·斯坦福大学托管委员会 产生苄基异喹啉生物碱(bia)前体的微生物以及制备和使用所述前体的方法
WO2015192233A1 (en) 2014-06-19 2015-12-23 Epimeron Inc. Compositions and methods for making (s)-norcoclaurine and (s)-norlaudanosoline, and synthesis intermediates thereof
CN106795486B (zh) 2014-08-21 2021-06-08 公益财团法人地球环境产业技术研究机构 棒状细菌转化体及使用该转化体的有机化合物的制造方法
WO2016183023A1 (en) * 2015-05-08 2016-11-17 The Board Of Trustees Of The Leland Stanford Junior University Methods of producing epimerases and benzylisoquinoline alkaloids
WO2018203947A2 (en) 2017-02-06 2018-11-08 Zymergen Inc. Engineered biosynthetic pathways for production of tyramine by fermentation

Similar Documents

Publication Publication Date Title
JP2020513790A5 (https=)
CN100529094C (zh) L-氨基酸的生产方法
JP4595506B2 (ja) L−アミノ酸生産菌及びl−アミノ酸の製造方法
US10781461B2 (en) Useful microorganism and method for producing substance of interest
CA2860974C (en) A microorganism of the genus escherichia having enhanced l-tryptophan productivity and a method for producing l-tryptophan using the same
CN111100834B (zh) 一种提高基因工程菌泛酸产量的构建方法及菌株
ES2273356T3 (es) Procedimiento para producir l-lisina.
CN102140431B (zh) L-色氨酸基因工程菌,其构建方法以及使用其发酵生产l-色氨酸的方法
JP6564929B2 (ja) コリネ型細菌形質転換体及びそれを用いる4−アミノ安息香酸又はその塩の製造方法
KR101714943B1 (ko) 이산화탄소 고정 회로를 도입한 미생물
RU2014123540A (ru) Микроорганизм для продуцирования одновременно L-аминокислоты и рибофлавина и способ производства L-аминокислоты и рибофлавина с его применением
CN1289675C (zh) 微生物制备芳族氨基酸的方法
Lynch et al. Method for producing 3-hydroxypropionic acid and other products
US9920343B2 (en) Method for producing aniline derivative by fermentation from carbon source
DK2806022T3 (en) Recombinant microorganism with improved putrescine productivity and method of producing putrescine using the same
CN113260706A (zh) 棒状细菌转化体以及使用其的2-苯基乙醇的制造方法
JP2022547466A (ja) 新規なプロモーター及びそれを用いた標的物質生産方法
WO2015117916A1 (en) Improved microorganisms for succinic acid production
CN112105716A (zh) 转化体以及使用其的有机化合物的制造方法
KR20200008997A (ko) 피루브산 카르복실라제 및 피루브산 카르복실라제 암호화 dna, 상기 dna를 함유한 플라스미드 및 그 생산을 위한 미생물, 그리고 자체의 생합성에서 전구체로서 옥살로아세테이트가 포함되는 것인 생성물의 제조 방법, 그리고 염색체
JP7034496B2 (ja) 芳香族化合物を産生する微生物
Ulfah Effect of feedback-resistant aroG overexpression on L-phenylalanine production in Escherichia coli
ZENG et al. Effects of Brevibacterium flavum with directed mutagenesis of ilvN and co-expression of ilvBNC cluster on L-valine production
TH55339A3 (th) อินทรีย์ที่มีชีวิตที่ผลิตได้ทางวิศวกรรมเผาผลาญสำหรับการเพิ่มการผลิตสารชีวเคมีที่อนุพันธ์มาจากออกซาโลอะซีเตต
TH47214C3 (th) อินทรีย์ที่มีชีวิตที่ผลิตได้ทางวิศวกรรมเผาผลาญสำหรับการเพิ่มการผลิตสารชีวเคมีที่อนุพันธ์มาจากออกซาโลอะซีเตต