|
AU509682B2
(en)
|
1975-10-28 |
1980-05-22 |
Eli Lilly And Company |
2-Aroyl-3-Phenylbenzothiophene Derivatives
|
|
US4133814A
(en)
|
1975-10-28 |
1979-01-09 |
Eli Lilly And Company |
2-Phenyl-3-aroylbenzothiophenes useful as antifertility agents
|
|
US4418068A
(en)
|
1981-04-03 |
1983-11-29 |
Eli Lilly And Company |
Antiestrogenic and antiandrugenic benzothiophenes
|
|
EP0146243A1
(en)
|
1983-10-31 |
1985-06-26 |
Merck Frosst Canada Inc. |
Lipoxygenase inhibitors
|
|
TW366342B
(en)
|
1992-07-28 |
1999-08-11 |
Lilly Co Eli |
The use of 2-phenyl-3-aroylbenzothiophenes in inhibiting bone loss
|
|
US5478847A
(en)
|
1994-03-02 |
1995-12-26 |
Eli Lilly And Company |
Methods of use for inhibiting bone loss and lowering serum cholesterol
|
|
US5834468A
(en)
|
1995-07-07 |
1998-11-10 |
Zeneca Limited |
Substituted aryl and heteroaryl compounds as E-type prostaglandin antagonists
|
|
US6458811B1
(en)
|
1996-03-26 |
2002-10-01 |
Eli Lilly And Company |
Benzothiophenes formulations containing same and methods
|
|
US5998402A
(en)
|
1996-04-19 |
1999-12-07 |
American Home Products Corporation |
2-phenyl-1-[4-(2-aminoethoxy)-benzyl]-indoles as estrogenic agents
|
|
TW397821B
(en)
|
1996-04-19 |
2000-07-11 |
American Home Produits Corp |
3-[4-(2-phenyl-indole-1-ylmethyl)-phenyl]-acrylamides and 2-phenyl-1-[4-(amino-1-yl-alk-1-ynyl)-benzyl]-1H-indol-5-ol as well as pharmaceutical compositions of estrogenic agents thereof
|
|
CA2306489A1
(en)
|
1997-10-03 |
1999-04-15 |
Mark Gregory Stocksdale |
Benzothiophenes
|
|
US6326392B1
(en)
|
1997-11-06 |
2001-12-04 |
American Home Products Corporation |
Anti-estrogen plus progestin containing oral contraceptives
|
|
ID24568A
(id)
|
1997-11-06 |
2000-07-27 |
American Home Prod |
Kontrasepsi oral yang mengandung anti-estrogen plus progestin
|
|
US6060488A
(en)
*
|
1998-09-22 |
2000-05-09 |
Eli Lilly And Company |
Benzothiophenes for treating estrogen deficiency
|
|
CO5271696A1
(es)
|
2000-01-12 |
2003-04-30 |
Pfizer Prod Inc |
Procedimiento para reducir la morbilidad y el riesgo de mortalidad
|
|
US7091240B2
(en)
|
2000-03-10 |
2006-08-15 |
Oxigene, Inc. |
Tubulin binding ligands and corresponding prodrug constructs
|
|
CN1450913A
(zh)
|
2000-07-06 |
2003-10-22 |
惠氏公司 |
二膦酸酯、雌激素药物以及任选雌激素的联合应用
|
|
WO2002003992A2
(en)
|
2000-07-06 |
2002-01-17 |
Wyeth |
Use of substituted indole compounds for treating prosthesis-related bone degeneration
|
|
AU2001271785A1
(en)
|
2000-07-06 |
2002-01-21 |
American Home Products Corporation |
Combinations of statins, estrogenic agents and optionally estrogens
|
|
US6358991B2
(en)
|
2000-07-06 |
2002-03-19 |
American Home Products Corporation |
Methods of treating neuropeptide Y-related conditions
|
|
EP1990051A1
(en)
|
2000-07-06 |
2008-11-12 |
Wyeth |
Combinations of SSRI and estrogenic agents
|
|
AR030064A1
(es)
|
2000-07-06 |
2003-08-13 |
Wyeth Corp |
Metodos para inhibir los efectos uterotroficos de los agentes estrogenicos
|
|
WO2002003986A2
(en)
|
2000-07-06 |
2002-01-17 |
Wyeth |
Use of substituted indole compounds for treating breast disorders
|
|
AU2001271781A1
(en)
|
2000-07-06 |
2002-01-21 |
Wyeth |
Use of substituted indole compounds for treating sphincter incontinence
|
|
AU2001271782A1
(en)
|
2000-07-06 |
2002-01-21 |
Wyeth |
Use of substituted insole compounds for treating excessive intraocular pressure
|
|
JP2004502734A
(ja)
|
2000-07-06 |
2004-01-29 |
ワイス |
一酸化窒素シンターゼ活性の増強方法
|
|
PT1318837E
(pt)
|
2000-08-11 |
2004-12-31 |
Wyeth Corp |
Metodo de tratamenton de carcinoma positivo a receptor de estrogenio
|
|
JP2007502307A
(ja)
|
2003-08-15 |
2007-02-08 |
アストラゼネカ アクチボラグ |
グルタミン酸ラセマーゼ（ｍｕｒｉ）の阻害剤としての縮合複素環
|
|
FR2862646B1
(fr)
|
2003-11-20 |
2006-02-24 |
Merck Sante Sas |
Nouveaux composes antidiabetiques contenant des derives benzofuranes, benzothiophenes
|
|
EP1846397A1
(en)
|
2005-01-21 |
2007-10-24 |
Janssen Pharmaceutica N.V. |
Novel heterocyclic benzoy[c]chromene derivatives useful as modulators of the estrogen receptors
|
|
CA2597447C
(en)
|
2005-02-14 |
2014-03-25 |
Bionomics Limited |
Novel tubulin polymerisation inhibitors
|
|
CA2640678C
(en)
|
2006-02-03 |
2015-03-31 |
Bionomics Limited |
Substituted benzofurans, benzothiophenes, benzoselenophenes and indoles and their use as tubulin polymerisation inhibitors
|
|
ES2436028T3
(es)
|
2006-06-23 |
2013-12-26 |
Radius Health, Inc. |
Tratamiento de síntomas vasomotores con moduladores selectivos de receptores de estrógeno
|
|
EP1947085A1
(en)
|
2007-01-19 |
2008-07-23 |
Laboratorios del Dr. Esteve S.A. |
Substituted indole sulfonamide compounds, their preparation and use as medicaments
|
|
CA2693207A1
(en)
|
2007-07-25 |
2009-01-29 |
F. Hoffmann-La Roche Ag |
Benzofuran- and benzo[b]thiophene-2-carboxylic acid amide derivatives and use thereof as histamine 3 receptor modulators
|
|
WO2010093578A1
(en)
|
2009-02-10 |
2010-08-19 |
Glaxo Group Limited |
Indolinyl-, benzofuranyl-, and benzothienyl- amides as modulators of chemokine receptors
|
|
US8809382B2
(en)
|
2009-05-04 |
2014-08-19 |
The Royal Institution For The Advancement Of Learning/Mcgill University |
5-oxo-ETE receptor antagonist compounds
|
|
CA2800673A1
(en)
|
2010-06-10 |
2011-12-15 |
Aragon Pharmaceuticals, Inc. |
Estrogen receptor modulators and uses thereof
|
|
GB2483736B
(en)
|
2010-09-16 |
2012-08-29 |
Aragon Pharmaceuticals Inc |
Estrogen receptor modulators and uses thereof
|
|
CA2819299A1
(en)
|
2010-12-24 |
2012-06-28 |
Merck Sharp & Dohme B.V. |
N-substituted azetidine derivatives
|
|
DE102011087987A1
(de)
|
2011-12-08 |
2013-06-13 |
Bayer Intellectual Property Gmbh |
6,7-Dihydro-5H-benzo[7]annulen-Derivate, Verfahren zu ihrer Herstellung, pharmazeutische Präparate die diese enthalten, sowie deren Verwendung zur Herstellung von Arzneimitteln
|
|
EA029559B1
(ru)
|
2011-12-14 |
2018-04-30 |
Серагон Фармасьютикалс, Инк. |
Фторированные модуляторы рецепторов эстрогенов и их применение
|
|
CN104169266A
(zh)
|
2011-12-16 |
2014-11-26 |
奥乐玛药物股份有限公司 |
新的苯并吡喃化合物、其组合物和用途
|
|
JP2015505562A
(ja)
|
2012-01-31 |
2015-02-23 |
ノバルティス アーゲー |
Ｒｔｋ阻害剤と抗エストロゲン剤との組合せ、およびがん治療のためのその使用
|
|
JP6154887B2
(ja)
|
2012-03-20 |
2017-06-28 |
セラゴン ファーマシューティカルズ，インク． |
エストロゲン受容体モジュレーターおよびその使用
|
|
ES2774935T3
(es)
|
2012-10-24 |
2020-07-23 |
Univ Illinois |
Composiciones y métodos para tratar trastornos médicos relacionados con estrógeno
|
|
WO2014066695A1
(en)
|
2012-10-24 |
2014-05-01 |
The Board Of Trustees Of The University Of Illinois |
Compositions and methods for treating estrogen-related medical disorders
|
|
CN105008343B
(zh)
|
2013-02-19 |
2017-12-08 |
诺华股份有限公司 |
作为选择性雌激素受体降解剂的苯并噻吩衍生物及其组合物
|
|
EP2970130A4
(en)
|
2013-03-14 |
2016-08-03 |
Seragon Pharmaceuticals Inc |
MODULATORS OF POLYCYCLIC STROGEN RECEPTORS AND USES THEREOF
|
|
UY35590A
(es)
|
2013-05-28 |
2014-11-28 |
Astrazeneca Ab |
Nuevos compuestos para el tratamiento del cáncer
|
|
KR20160021277A
(ko)
|
2013-06-19 |
2016-02-24 |
세라곤 파마슈티컬스, 인크. |
에스트로겐 수용체 조절제 및 이의 용도
|
|
WO2014203129A1
(en)
|
2013-06-19 |
2014-12-24 |
Olema Pharmaceuticals, Inc. |
Combinations of benzopyran compounds, compositions and uses thereof
|
|
CA2915534A1
(en)
|
2013-06-19 |
2014-12-24 |
Seragon Pharmaceuticals, Inc. |
Azetidine estrogen receptor modulators and uses thereof
|
|
WO2014203132A1
(en)
|
2013-06-19 |
2014-12-24 |
Olema Pharmaceuticals, Inc. |
Substituted benzopyran compounds, compositions and uses thereof
|
|
GB201311888D0
(en)
*
|
2013-07-03 |
2013-08-14 |
Glaxosmithkline Ip Dev Ltd |
Novel compounds
|
|
WO2015028409A1
(de)
|
2013-08-27 |
2015-03-05 |
Bayer Pharma Aktiengesellschaft |
6,7-dihydro-5h-benzo[7]annulen-derivate, verfahren zu ihrer herstellung, pharmazeutische präparate die diese enthalten, sowie deren verwendung zur herstellung von arzneimitteln
|
|
WO2015092634A1
(en)
|
2013-12-16 |
2015-06-25 |
Novartis Ag |
1,2,3,4-tetrahydroisoquinoline compounds and compositions as selective estrogen receptor antagonists and degraders
|
|
CA2940576A1
(en)
|
2014-03-13 |
2015-09-17 |
F. Hoffmann-La Roche Ag |
Therapeutic combinations with estrogen receptor modulators
|
|
AU2015228860A1
(en)
|
2014-03-13 |
2016-09-08 |
F. Hoffmann-La Roche Ag |
Methods and compositions for modulating estrogen receptor mutants
|
|
FI3834824T3
(fi)
|
2014-03-28 |
2025-12-05 |
Univ Duke |
Estrogeenireseptoripositiivisen rintasyövän hoito selektiivisellä estrogeenireseptorin modulaattorilla
|
|
ES2819448T3
(es)
|
2014-12-18 |
2021-04-16 |
Hoffmann La Roche |
Tetrahidro-pirido[3,4-b]indoles como moduladores del receptor de estrógenos y usos de los mismos
|
|
WO2016097073A1
(en)
|
2014-12-18 |
2016-06-23 |
F. Hoffmann-La Roche Ag |
Derivatives of 2,3-diphenylchromene useful for the treatment of cancer
|
|
WO2016097071A1
(en)
|
2014-12-18 |
2016-06-23 |
F. Hoffmann-La Roche Ag |
Estrogen receptor modulators and uses thereof
|
|
WO2016189011A1
(en)
|
2015-05-26 |
2016-12-01 |
F. Hoffmann-La Roche Ag |
Heterocyclic estrogen receptor modulators and uses thereof
|
|
RU2745742C1
(ru)
|
2015-10-01 |
2021-03-31 |
Олема Фармасьютикалз, Инк. |
ТЕТРАГИДРО-1Н-ПИРИДО[3,4-b]ИНДОЛЬНЫЕ АНТИЭСТРОГЕННЫЕ ЛЕКАРСТВЕННЫЕ СРЕДСТВА
|
|
WO2017056115A1
(en)
|
2015-10-03 |
2017-04-06 |
Sun Pharma Advanced Research Company Limited |
Novel n-aryl containing fused heterocyclic compounds
|
|
EP3359527A1
(en)
|
2015-10-07 |
2018-08-15 |
H. Hoffnabb-La Roche Ag |
Process for the preparation of (e)-3-(4-((e)-2-(2-chloro-4-fluorophenyl)-1-(1h-indazol-5-yl)but-1-en-1-yl)phenyl)acrylic acid
|
|
EA034131B1
(ru)
|
2015-10-27 |
2020-01-09 |
Сан Фарма Адвансед Ресёрч Компани Лимитед |
Гетероциклические антиэстрогены
|
|
CN108495628B
(zh)
|
2015-12-09 |
2022-01-11 |
伊利诺伊大学评议会 |
苯并噻吩基选择性雌激素受体下调剂
|
|
MX386677B
(es)
|
2016-02-15 |
2025-03-19 |
Sanofi Sa |
Derivados de 6,7-dihidro-5h-benzo[7]anuleno como moduladores de receptores de estrogenos
|