|
AU509682B2
(en)
|
1975-10-28 |
1980-05-22 |
Eli Lilly And Company |
2-Aroyl-3-Phenylbenzothiophene Derivatives
|
|
US4133814A
(en)
|
1975-10-28 |
1979-01-09 |
Eli Lilly And Company |
2-Phenyl-3-aroylbenzothiophenes useful as antifertility agents
|
|
US4418068A
(en)
|
1981-04-03 |
1983-11-29 |
Eli Lilly And Company |
Antiestrogenic and antiandrugenic benzothiophenes
|
|
EP0146243A1
(en)
|
1983-10-31 |
1985-06-26 |
Merck Frosst Canada Inc. |
Lipoxygenase inhibitors
|
|
TW366342B
(en)
|
1992-07-28 |
1999-08-11 |
Lilly Co Eli |
The use of 2-phenyl-3-aroylbenzothiophenes in inhibiting bone loss
|
|
US5478847A
(en)
|
1994-03-02 |
1995-12-26 |
Eli Lilly And Company |
Methods of use for inhibiting bone loss and lowering serum cholesterol
|
|
EP0752421B1
(en)
|
1995-07-07 |
2005-10-12 |
AstraZeneca AB |
Ortho-substituted aromatic compounds, containing three (het)aryl moieties, their preparation and their use as prostaglandin E2-(PGE2)-antagonists
|
|
US6458811B1
(en)
|
1996-03-26 |
2002-10-01 |
Eli Lilly And Company |
Benzothiophenes formulations containing same and methods
|
|
US5998402A
(en)
|
1996-04-19 |
1999-12-07 |
American Home Products Corporation |
2-phenyl-1-[4-(2-aminoethoxy)-benzyl]-indoles as estrogenic agents
|
|
TW397821B
(en)
|
1996-04-19 |
2000-07-11 |
American Home Produits Corp |
3-[4-(2-phenyl-indole-1-ylmethyl)-phenyl]-acrylamides and 2-phenyl-1-[4-(amino-1-yl-alk-1-ynyl)-benzyl]-1H-indol-5-ol as well as pharmaceutical compositions of estrogenic agents thereof
|
|
JP2001519349A
(ja)
|
1997-10-03 |
2001-10-23 |
イーライ・リリー・アンド・カンパニー |
ベンゾチオフェン
|
|
US6326392B1
(en)
|
1997-11-06 |
2001-12-04 |
American Home Products Corporation |
Anti-estrogen plus progestin containing oral contraceptives
|
|
ID24568A
(id)
|
1997-11-06 |
2000-07-27 |
American Home Prod |
Kontrasepsi oral yang mengandung anti-estrogen plus progestin
|
|
US6060488A
(en)
*
|
1998-09-22 |
2000-05-09 |
Eli Lilly And Company |
Benzothiophenes for treating estrogen deficiency
|
|
CO5271696A1
(es)
|
2000-01-12 |
2003-04-30 |
Pfizer Prod Inc |
Procedimiento para reducir la morbilidad y el riesgo de mortalidad
|
|
US7091240B2
(en)
|
2000-03-10 |
2006-08-15 |
Oxigene, Inc. |
Tubulin binding ligands and corresponding prodrug constructs
|
|
CA2414111A1
(en)
|
2000-07-06 |
2002-01-17 |
Wyeth |
Use of substituted indole compounds for increasing nitric oxide synthase activity
|
|
US6509332B2
(en)
|
2000-07-06 |
2003-01-21 |
Wyeth |
Methods of treating excessive intraocular pressure
|
|
AR030064A1
(es)
|
2000-07-06 |
2003-08-13 |
Wyeth Corp |
Metodos para inhibir los efectos uterotroficos de los agentes estrogenicos
|
|
US6358991B2
(en)
|
2000-07-06 |
2002-03-19 |
American Home Products Corporation |
Methods of treating neuropeptide Y-related conditions
|
|
JP2004502729A
(ja)
|
2000-07-06 |
2004-01-29 |
ワイス |
Ssriおよびエストロゲン剤の組み合わせ
|
|
AU2001271781A1
(en)
|
2000-07-06 |
2002-01-21 |
Wyeth |
Use of substituted indole compounds for treating sphincter incontinence
|
|
CA2414060A1
(en)
|
2000-07-06 |
2002-01-17 |
Wyeth |
Combinations of statins, estrogenic agents and optionally estrogens
|
|
AU2001271706A1
(en)
|
2000-07-06 |
2002-01-21 |
American Home Products Corporation |
Use of substituted indole compounds for treating breast disorders
|
|
WO2002003976A2
(en)
|
2000-07-06 |
2002-01-17 |
Wyeth |
Combinations of bisphosphonates, estrogenic agents and optionally estrogens
|
|
WO2002003992A2
(en)
|
2000-07-06 |
2002-01-17 |
Wyeth |
Use of substituted indole compounds for treating prosthesis-related bone degeneration
|
|
DK1318837T3
(da)
|
2000-08-11 |
2005-01-10 |
Wyeth Corp |
Fremgangsmåde til behandling af östrogenreceptorpositivt carcinom
|
|
JP2007502307A
(ja)
|
2003-08-15 |
2007-02-08 |
アストラゼネカ アクチボラグ |
グルタミン酸ラセマーゼ(muri)の阻害剤としての縮合複素環
|
|
FR2862646B1
(fr)
|
2003-11-20 |
2006-02-24 |
Merck Sante Sas |
Nouveaux composes antidiabetiques contenant des derives benzofuranes, benzothiophenes
|
|
WO2006078834A1
(en)
|
2005-01-21 |
2006-07-27 |
Janssen Pharmaceutica N.V. |
Novel heterocyclic benzo[c]chromene derivatives useful as modulators of the estrogen receptors
|
|
US8278290B2
(en)
|
2005-02-14 |
2012-10-02 |
Biononics Limited |
Tubulin polymerisation inhibitors
|
|
NZ570014A
(en)
|
2006-02-03 |
2011-04-29 |
Bionomics Ltd |
Substituted benzofurans, benzothiophenes, benzoselenophenes and indoles and their use as tubulin polymerisation inhibitors
|
|
WO2008002490A2
(en)
|
2006-06-23 |
2008-01-03 |
Radius Health, Inc. |
Treatment of vasomotor symptoms with selective estrogen receptor modulators
|
|
EP1947085A1
(en)
|
2007-01-19 |
2008-07-23 |
Laboratorios del Dr. Esteve S.A. |
Substituted indole sulfonamide compounds, their preparation and use as medicaments
|
|
US7534788B2
(en)
|
2007-07-25 |
2009-05-19 |
Hoffmann-La Roche Inc. |
Benzofuran and benzothiophene-2-carboxylic acid amide derivatives
|
|
WO2010093578A1
(en)
|
2009-02-10 |
2010-08-19 |
Glaxo Group Limited |
Indolinyl-, benzofuranyl-, and benzothienyl- amides as modulators of chemokine receptors
|
|
WO2010127452A1
(en)
|
2009-05-04 |
2010-11-11 |
The Royal Institution For The Advancement Of Learning/Mcgill University |
5-oxo-ete receptor antagonist compounds
|
|
BR112012031464A2
(pt)
|
2010-06-10 |
2020-08-04 |
Aragon Pharmaceuticals, Inc. |
moduladores do receptor de estrogênio e os seus usos
|
|
GB2483736B
(en)
|
2010-09-16 |
2012-08-29 |
Aragon Pharmaceuticals Inc |
Estrogen receptor modulators and uses thereof
|
|
AU2011347718B2
(en)
|
2010-12-24 |
2016-06-23 |
Msd Oss B.V. |
N-substituted azetidine derivatives
|
|
DE102011087987A1
(de)
|
2011-12-08 |
2013-06-13 |
Bayer Intellectual Property Gmbh |
6,7-Dihydro-5H-benzo[7]annulen-Derivate, Verfahren zu ihrer Herstellung, pharmazeutische Präparate die diese enthalten, sowie deren Verwendung zur Herstellung von Arzneimitteln
|
|
SG11201403002RA
(en)
|
2011-12-14 |
2014-07-30 |
Seragon Pharmaceuticals Inc |
Fluorinated estrogen receptor modulators and uses thereof
|
|
EA201490897A1
(ru)
|
2011-12-16 |
2015-03-31 |
Олема Фармасьютикалс, Инк. |
Новые бензопирановые соединения, композиции и их применение
|
|
KR20140117457A
(ko)
|
2012-01-31 |
2014-10-07 |
노파르티스 아게 |
Rtk 억제제와 항에스트로겐의 조합물 및 암의 치료를 위한 그의 용도
|
|
EA201491530A1
(ru)
|
2012-03-20 |
2015-07-30 |
Серагон Фармасьютикалс, Инк. |
Модуляторы рецепторов эстрогенов и их применение
|
|
ES2774935T3
(es)
|
2012-10-24 |
2020-07-23 |
Univ Illinois |
Composiciones y métodos para tratar trastornos médicos relacionados con estrógeno
|
|
WO2014066695A1
(en)
|
2012-10-24 |
2014-05-01 |
The Board Of Trustees Of The University Of Illinois |
Compositions and methods for treating estrogen-related medical disorders
|
|
EP2958907B1
(en)
*
|
2013-02-19 |
2018-02-28 |
Novartis AG |
Benzothiophene derivatives and compositions thereof as selective estrogen receptor degraders
|
|
JP2016517420A
(ja)
|
2013-03-14 |
2016-06-16 |
セラゴン ファーマシューティカルズ, インク. |
多環式エストロゲン受容体モジュレーター及びその使用
|
|
DK3004090T3
(en)
|
2013-05-28 |
2018-01-08 |
Astrazeneca Ab |
CHEMICAL COMPOUNDS
|
|
WO2014203132A1
(en)
|
2013-06-19 |
2014-12-24 |
Olema Pharmaceuticals, Inc. |
Substituted benzopyran compounds, compositions and uses thereof
|
|
WO2014203129A1
(en)
|
2013-06-19 |
2014-12-24 |
Olema Pharmaceuticals, Inc. |
Combinations of benzopyran compounds, compositions and uses thereof
|
|
BR112015031903A8
(pt)
|
2013-06-19 |
2019-12-31 |
Seragon Pharmaceuticals Inc |
composto, sal farmaceuticamente aceitável, composição farmacêutica e uso de um composto
|
|
WO2014205136A1
(en)
|
2013-06-19 |
2014-12-24 |
Seragon Pharmaceuticals, Inc. |
Azetidine estrogen receptor modulators and uses thereof
|
|
GB201311888D0
(en)
|
2013-07-03 |
2013-08-14 |
Glaxosmithkline Ip Dev Ltd |
Novel compounds
|
|
WO2015028409A1
(de)
|
2013-08-27 |
2015-03-05 |
Bayer Pharma Aktiengesellschaft |
6,7-dihydro-5h-benzo[7]annulen-derivate, verfahren zu ihrer herstellung, pharmazeutische präparate die diese enthalten, sowie deren verwendung zur herstellung von arzneimitteln
|
|
WO2015092634A1
(en)
|
2013-12-16 |
2015-06-25 |
Novartis Ag |
1,2,3,4-tetrahydroisoquinoline compounds and compositions as selective estrogen receptor antagonists and degraders
|
|
JP2017507964A
(ja)
|
2014-03-13 |
2017-03-23 |
エフ・ホフマン−ラ・ロシュ・アクチェンゲゼルシャフト |
エストロゲン受容体モジュレーターを用いた治療的組合せ
|
|
AU2015228860A1
(en)
|
2014-03-13 |
2016-09-08 |
F. Hoffmann-La Roche Ag |
Methods and compositions for modulating estrogen receptor mutants
|
|
EP4035664A3
(en)
|
2014-03-28 |
2022-11-30 |
Duke University |
Treating cancer using selective estrogen receptor modulators
|
|
CN112375078B
(zh)
|
2014-12-18 |
2023-12-19 |
豪夫迈·罗氏有限公司 |
四氢-吡啶并[3,4-b]吲哚雌激素受体调节剂及其用途
|
|
WO2016097073A1
(en)
|
2014-12-18 |
2016-06-23 |
F. Hoffmann-La Roche Ag |
Derivatives of 2,3-diphenylchromene useful for the treatment of cancer
|
|
US9845291B2
(en)
|
2014-12-18 |
2017-12-19 |
Genentech, Inc. |
Estrogen receptor modulators and uses thereof
|
|
CN107531722B
(zh)
|
2015-05-26 |
2020-07-17 |
豪夫迈·罗氏有限公司 |
杂环雌激素受体调节剂及其用途
|
|
KR102710603B1
(ko)
|
2015-10-01 |
2024-09-27 |
올레마 파마슈티컬스 인코포레이티드 |
테트라히드로-1H-피리도[3,4-b]인돌 항에스트로겐 약물
|
|
WO2017056115A1
(en)
|
2015-10-03 |
2017-04-06 |
Sun Pharma Advanced Research Company Limited |
Novel n-aryl containing fused heterocyclic compounds
|
|
EP3359527A1
(en)
|
2015-10-07 |
2018-08-15 |
H. Hoffnabb-La Roche Ag |
Process for the preparation of (e)-3-(4-((e)-2-(2-chloro-4-fluorophenyl)-1-(1h-indazol-5-yl)but-1-en-1-yl)phenyl)acrylic acid
|
|
SG11201803119XA
(en)
|
2015-10-27 |
2018-05-30 |
Sun Pharma Advanced Res Co Ltd |
Novel heterocyclic antiestrogens
|
|
NZ743651A
(en)
|
2015-12-09 |
2023-07-28 |
Univ Illinois |
Benzothiophene-based selective estrogen receptor downregulators
|
|
MA46479A
(fr)
|
2016-02-15 |
2019-08-14 |
Sanofi Sa |
Procédés et intermédiaires pour la préparation de nouveaux composés substitués de 6,7-dihydro-5h-benzo[7]annulène
|