JP2020500508A - ユビキチンc末端ヒドロラーゼl1(uch−l1)およびグリア線維酸性タンパク質(gfap)に対する抗体および関連する方法 - Google Patents

ユビキチンc末端ヒドロラーゼl1(uch−l1)およびグリア線維酸性タンパク質(gfap)に対する抗体および関連する方法 Download PDF

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JP2020500508A
JP2020500508A JP2019523743A JP2019523743A JP2020500508A JP 2020500508 A JP2020500508 A JP 2020500508A JP 2019523743 A JP2019523743 A JP 2019523743A JP 2019523743 A JP2019523743 A JP 2019523743A JP 2020500508 A JP2020500508 A JP 2020500508A
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cdr
amino acid
acid sequence
chain variable
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マイケル カタニア
マイケル カタニア
ロナルド エル. ヘイズ
ロナルド エル. ヘイズ
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バンヤン・バイオマーカーズ・インコーポレーテッド
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JP2019523743A 2016-10-28 2017-10-27 ユビキチンc末端ヒドロラーゼl1(uch−l1)およびグリア線維酸性タンパク質(gfap)に対する抗体および関連する方法 Pending JP2020500508A (ja)

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JP2022127035A JP7431289B2 (ja) 2016-10-28 2022-08-09 ユビキチンc末端ヒドロラーゼl1(uch-l1)およびグリア線維酸性タンパク質(gfap)に対する抗体および関連する方法
JP2024011555A JP7832969B2 (ja) 2016-10-28 2024-01-30 ユビキチンc末端ヒドロラーゼl1(uch-l1)およびグリア線維酸性タンパク質(gfap)に対する抗体および関連する方法

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US201662414569P 2016-10-28 2016-10-28
US62/414,569 2016-10-28
PCT/US2017/058881 WO2018081649A1 (en) 2016-10-28 2017-10-27 Antibodies to ubiquitin c-terminal hydrolase l1 (uch-l1) and glial fibrillary acidic protein (gfap) and related methods

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JP2022127035A Active JP7431289B2 (ja) 2016-10-28 2022-08-09 ユビキチンc末端ヒドロラーゼl1(uch-l1)およびグリア線維酸性タンパク質(gfap)に対する抗体および関連する方法
JP2024011555A Active JP7832969B2 (ja) 2016-10-28 2024-01-30 ユビキチンc末端ヒドロラーゼl1(uch-l1)およびグリア線維酸性タンパク質(gfap)に対する抗体および関連する方法

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JP2024011555A Active JP7832969B2 (ja) 2016-10-28 2024-01-30 ユビキチンc末端ヒドロラーゼl1(uch-l1)およびグリア線維酸性タンパク質(gfap)に対する抗体および関連する方法

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US (3) US11078298B2 (enExample)
EP (1) EP3532496A1 (enExample)
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JP2020521951A (ja) * 2017-05-25 2020-07-27 アボット・ラボラトリーズAbbott Laboratories 早期バイオマーカーを使用する、頭部への損傷を負ったヒト対象又は負った可能性があるヒト対象に対して、イメージングを実施するかどうかの決定の一助となるための方法
CN120137027A (zh) * 2023-12-13 2025-06-13 东莞市朋志生物科技有限公司 抗胃泌素释放肽前体抗体及其用途

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EP3336551B1 (en) 2008-08-11 2023-05-31 Banyan Biomarkers, Inc. Biomarker detection process and assay of neurological condition
US12601749B2 (en) 2008-08-11 2026-04-14 Banyan Biomarkers, Inc. Biomarker detection process and assay of neurological condition
JP2020500508A (ja) 2016-10-28 2020-01-16 バンヤン・バイオマーカーズ・インコーポレーテッド ユビキチンc末端ヒドロラーゼl1(uch−l1)およびグリア線維酸性タンパク質(gfap)に対する抗体および関連する方法
JP7346300B2 (ja) 2017-03-23 2023-09-19 アボット・ラボラトリーズ 早期バイオマーカーであるユビキチンカルボキシ末端ヒドロラーゼl1を使用する、ヒト対象における外傷性脳損傷の程度の診断及び決定の一助となるための方法
EP3610268B1 (en) 2017-04-15 2025-09-24 Abbott Laboratories Methods for aiding in the hyperacute diagnosis and determination of traumatic brain injury in a human subject using early biomarkers
JP7080899B2 (ja) 2017-04-28 2022-06-06 アボット・ラボラトリーズ 同じヒト対象に由来する少なくとも2つの試料に対して早期バイオマーカーを使用する、外傷性脳損傷の超急性の診断及び決定の一助となるための方法
WO2018222783A1 (en) 2017-05-30 2018-12-06 Abbott Laboratories Methods for aiding in diagnosing and evaluating a mild traumatic brain injury in a human subject using cardiac troponin i and early biomarkers
EP3649474A1 (en) 2017-07-03 2020-05-13 Abbott Laboratories Improved methods for measuring ubiquitin carboxy-terminal hydrolase l1 levels in blood
WO2019113525A2 (en) 2017-12-09 2019-06-13 Abbott Laboratories Methods for aiding in the diagnosis and evaluation of a subject who has sustained an orthopedic injury and that has or may have sustained an injury to the head, such as mild traumatic brain injury (tbi), using glial fibrillary acidic protein (gfap) and/or ubiquitin carboxy-terminal hydrolase l1 (uch-l1)
WO2019112860A1 (en) 2017-12-09 2019-06-13 Abbott Laboratories Methods for aiding in diagnosing and evaluating a traumatic brain injury in a human subject using a combination of gfap and uch-l1
WO2019133717A1 (en) 2017-12-29 2019-07-04 Abbott Laboratories Novel biomarkers and methods for diagnosing and evaluating traumatic brain injury
CN109306007B (zh) * 2018-09-26 2021-10-08 华中农业大学 抗猪繁殖与呼吸综合征病毒nsp4蛋白基因工程抗体及应用
JP7617040B2 (ja) * 2019-06-13 2025-01-17 プレステージ バイオファーマ リミテッド Cthrc1に特異的な新規抗体及びその使用
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WO2021055816A1 (en) 2019-09-18 2021-03-25 Molecular Templates, Inc. Pd-l1 binding molecules comprising shiga toxin a subunit scaffolds
CN115052663B (zh) 2020-01-08 2026-06-09 辛瑟斯治疗股份有限公司 Alk5抑制剂缀合物及其用途
CN112457406B (zh) * 2020-11-27 2022-05-31 中国科学院上海药物研究所 一种抗mmae的单克隆抗体、其编码序列及应用
EP4262858A1 (en) * 2020-12-16 2023-10-25 Molecular Templates, Inc. Clinical methods for use of a pd-l1-binding molecule comprising a shiga toxin effector
WO2022221314A1 (en) * 2021-04-16 2022-10-20 BioLegend, Inc. Compositions and methods involving severe acute respiratory syndrome coronavirus 2 receptor binding domain
AU2022279156A1 (en) 2021-05-18 2023-11-02 Abbott Laboratories Methods of evaluating brain injury in a pediatric subject
CN113970643B (zh) * 2021-11-23 2023-06-30 北京大学人民医院 检测抗uch-l1表位的自身抗体的试剂在制备sle血清诊断相关产品中的应用
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