JP2020125349A5 - - Google Patents
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- JP2020125349A5 JP2020125349A5 JP2020081156A JP2020081156A JP2020125349A5 JP 2020125349 A5 JP2020125349 A5 JP 2020125349A5 JP 2020081156 A JP2020081156 A JP 2020081156A JP 2020081156 A JP2020081156 A JP 2020081156A JP 2020125349 A5 JP2020125349 A5 JP 2020125349A5
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- Prior art keywords
- lymphoma
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- cancer
- leukemia
- agents
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- 206010028980 Neoplasm Diseases 0.000 claims 26
- 201000011510 cancer Diseases 0.000 claims 13
- 239000003795 chemical substances by application Substances 0.000 claims 11
- 150000001875 compounds Chemical class 0.000 claims 11
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- 208000037265 diseases, disorders, signs and symptoms Diseases 0.000 claims 10
- 150000003839 salts Chemical class 0.000 claims 10
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- 229960005486 vaccine Drugs 0.000 claims 5
- 125000004169 (C1-C6) alkyl group Chemical group 0.000 claims 4
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Applications Claiming Priority (4)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| GBGB1419570.5A GB201419570D0 (en) | 2014-11-03 | 2014-11-03 | Pharmaceutical compound |
| GB1419570.5 | 2014-11-03 | ||
| GBGB1507883.5A GB201507883D0 (en) | 2015-05-08 | 2015-05-08 | Pharmaceutical compound |
| GB1507883.5 | 2015-05-08 |
Related Parent Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2017542315A Division JP6701214B2 (ja) | 2014-11-03 | 2015-11-02 | 医薬化合物 |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2020125349A JP2020125349A (ja) | 2020-08-20 |
| JP2020125349A5 true JP2020125349A5 (enExample) | 2020-10-15 |
| JP6994538B2 JP6994538B2 (ja) | 2022-01-14 |
Family
ID=54476948
Family Applications (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2017542315A Active JP6701214B2 (ja) | 2014-11-03 | 2015-11-02 | 医薬化合物 |
| JP2020081156A Active JP6994538B2 (ja) | 2014-11-03 | 2020-05-01 | 医薬化合物 |
Family Applications Before (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2017542315A Active JP6701214B2 (ja) | 2014-11-03 | 2015-11-02 | 医薬化合物 |
Country Status (10)
| Country | Link |
|---|---|
| US (2) | US10590086B2 (enExample) |
| EP (1) | EP3215156B1 (enExample) |
| JP (2) | JP6701214B2 (enExample) |
| KR (1) | KR102602947B1 (enExample) |
| CN (2) | CN111943890B (enExample) |
| AU (1) | AU2015341913B2 (enExample) |
| CA (1) | CA2965741C (enExample) |
| MX (1) | MX390081B (enExample) |
| RU (1) | RU2719446C2 (enExample) |
| WO (1) | WO2016071293A2 (enExample) |
Families Citing this family (81)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| NZ582150A (en) | 2007-06-18 | 2012-08-31 | Msd Oss Bv | Antibodies to human programmed death receptor pd-1 |
| US10590086B2 (en) | 2014-11-03 | 2020-03-17 | Iomet Pharma Ltd. | Pharmaceutical compound |
| JO3637B1 (ar) | 2015-04-28 | 2020-08-27 | Janssen Sciences Ireland Uc | مركبات بيرازولو- وترايازولو- بيريميدين مضادة للفيروسات rsv |
| KR101997241B1 (ko) | 2015-05-21 | 2019-07-09 | 하푼 테라퓨틱스, 인크. | 삼중특이성 결합 단백질 및 사용 방법 |
| MX2021006804A (es) | 2015-12-17 | 2023-01-13 | Merck Patent Gmbh | Antagonistas policiclicos del receptor 7/8 tipo toll (tlr7/8) y uso de los mismos en el tratamiento de trastornos inmunitarios. |
| CN107033087B (zh) * | 2016-02-04 | 2020-09-04 | 西华大学 | 1h-吲唑-4-胺类化合物及其作为ido抑制剂的用途 |
| CN107619392B (zh) * | 2016-07-15 | 2021-01-01 | 西华大学 | 1h-吲唑-4-醚类化合物及其作为ido抑制剂的用途 |
| WO2017133258A1 (zh) * | 2016-02-04 | 2017-08-10 | 西华大学 | 1h-吲唑类衍生物及其作为ido抑制剂的用途 |
| CN107840826B (zh) * | 2016-09-19 | 2021-07-09 | 西华大学 | 1h-吲唑类衍生物及其作为ido抑制剂的用途 |
| BR112018071602B1 (pt) | 2016-04-29 | 2024-02-27 | Iomet Pharma Ltd. | Compostos de imidazopiridina substituídos, sua composição e seus usos como inibidores da indolamina 2,3-dioxigenase e/ou triptofano-2,3- dioxigenase |
| US11623958B2 (en) | 2016-05-20 | 2023-04-11 | Harpoon Therapeutics, Inc. | Single chain variable fragment CD3 binding proteins |
| CN107556244B (zh) * | 2016-07-01 | 2021-09-03 | 上海迪诺医药科技有限公司 | 并环化合物、其药物组合物及应用 |
| EP3269714A1 (en) | 2016-07-13 | 2018-01-17 | Netherlands Translational Research Center B.V. | Inhibitors of tryptophan 2,3-dioxygenase |
| CN107674029A (zh) * | 2016-08-02 | 2018-02-09 | 上海迪诺医药科技有限公司 | 多环化合物、其药物组合物及应用 |
| RU2758686C2 (ru) | 2016-08-08 | 2021-11-01 | Мерк Патент Гмбх | Антагонисты tlr7/8 и их применение |
| AU2017315572B2 (en) * | 2016-08-23 | 2021-07-15 | Beijing Innocare Pharma Tech Co., Ltd. | Fused heterocyclic derivative, preparation method therefor and medical use thereof |
| TW201815766A (zh) * | 2016-09-22 | 2018-05-01 | 美商普雷辛肯公司 | 用於ido及tdo調節之化合物及方法以及其適應症 |
| CN109952300B (zh) * | 2016-09-24 | 2022-01-18 | 百济神州有限公司 | 5或8-取代的咪唑并[1,5-a]吡啶 |
| US10961238B2 (en) | 2016-10-26 | 2021-03-30 | E-Therapeutics Plc | Modulators of hedgehog (Hh) signaling pathway |
| JP2020506895A (ja) | 2017-01-17 | 2020-03-05 | ボード オブ レジェンツ, ザ ユニバーシティ オブ テキサス システムBoard Of Regents, The University Of Texas System | インドールアミン2,3−ジオキシゲナーゼおよび/またはトリプトファンジオキシゲナーゼの阻害剤として有用な化合物 |
| KR102294129B1 (ko) * | 2017-03-16 | 2021-08-27 | 국제약품 주식회사 | N-벤질-n-페녹시카르보닐-페닐설폰아마이드 유도체 및 그를 포함하는 약제학적 조성물 |
| CN108689937B (zh) * | 2017-04-10 | 2021-09-17 | 西华大学 | 吲唑类化合物及其在制备ido抑制剂类药物上的用途 |
| CN108689938B (zh) * | 2017-04-10 | 2021-07-30 | 西华大学 | 多取代的吲唑类化合物及其作为ido抑制剂的用途 |
| CN108689936B (zh) * | 2017-04-10 | 2021-09-10 | 西华大学 | 含氮取代基的吲唑类化合物及其作为ido抑制剂的用途 |
| AU2018265856B2 (en) | 2017-05-12 | 2023-04-27 | Harpoon Therapeutics, Inc. | Mesothelin binding proteins |
| CA3060989A1 (en) | 2017-05-30 | 2018-12-06 | Bristol-Myers Squibb Company | Compositions comprising a combination of an anti-lag-3 antibody, a pd-1 pathway inhibitor, and an immunotherapeutic agent |
| EP3645538A1 (en) * | 2017-06-28 | 2020-05-06 | GlaxoSmithKline Intellectual Property Development Limited | Modulators of indoleamine 2,3-dioxygenase |
| BR112020002265A2 (pt) | 2017-08-01 | 2020-07-28 | Theravance Biopharma R&D Ip, Llc | compostos pirazólicos e triazólicos bicíclicos como inibidores de jak quiinase |
| IL315737A (en) | 2017-10-13 | 2024-11-01 | Harpoon Therapeutics Inc | B-cell maturation antigen-binding proteins |
| WO2019075359A1 (en) | 2017-10-13 | 2019-04-18 | Harpoon Therapeutics, Inc. | TRISPECIFIC PROTEINS AND METHODS OF USE |
| EP3697791A4 (en) * | 2017-10-19 | 2021-06-16 | JS Innopharm (Shanghai) Ltd. | HETEROCYCLIC COMPOUNDS, COMPOSITIONS INCLUDING THE HETEROCYCLIC COMPOUND, AND METHODS OF USE THEREOF |
| JP7306634B2 (ja) | 2017-10-19 | 2023-07-11 | 一般社団法人ファルマバレープロジェクト支援機構 | Ido/tdo阻害剤 |
| US11759461B2 (en) | 2017-10-30 | 2023-09-19 | The Scripps Research Institute | Small molecule inhibitors of cancer stem cells and mesenchymal cancer types |
| CN111386114A (zh) | 2017-11-25 | 2020-07-07 | 百济神州有限公司 | 作为吲哚胺2,3-双加氧酶的选择性抑制剂的新颖苯并咪唑 |
| TW201932470A (zh) | 2017-11-29 | 2019-08-16 | 愛爾蘭商健生科學愛爾蘭無限公司 | 具有抗rsv活性之吡唑并嘧啶 |
| CN108586378B (zh) | 2018-01-22 | 2020-06-19 | 南京华威医药科技集团有限公司 | 吲哚胺2,3-双加氧化酶抑制剂及其制备方法和用途 |
| KR20200116481A (ko) | 2018-01-29 | 2020-10-12 | 메르크 파텐트 게엠베하 | Gcn2 억제제 및 이의 용도 |
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- 2015-11-02 RU RU2017118160A patent/RU2719446C2/ru active
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