|
US1082231A
(en)
*
|
1913-03-26 |
1913-12-23 |
E J Hudnall |
Method of setting tiles, bricks, and mosaics.
|
|
IT1211135B
(it)
*
|
1981-11-24 |
1989-09-29 |
Ausonia Farma Srl |
Composti ad attivita'analgesica e antiinfiammatoria, processo per la loro preparazione e relative composizioni farmaceutiche.
|
|
FR2665159B1
(fr)
*
|
1990-07-24 |
1992-11-13 |
Rhone Poulenc Sante |
Nouveaux derives de la pyridine et de la quinoleine, leur preparation et les compositions pharmaceutiques qui les contiennent.
|
|
NZ257955A
(en)
|
1992-12-02 |
1996-05-28 |
Pfizer |
Catechol diethers pharmaceutical compositions
|
|
US5665777A
(en)
*
|
1995-11-14 |
1997-09-09 |
Abbott Laboratories |
Biphenyl hydroxamate inhibitors of matrix metalloproteinases
|
|
DE19633746A1
(de)
*
|
1996-08-22 |
1998-02-26 |
Basf Ag |
Substituierte 2-Phenylpyridine
|
|
US6576664B1
(en)
|
1997-08-18 |
2003-06-10 |
Bristol-Myers Squibb Pharma Company |
Inhibitors of aggrecanase and matrix metalloproteinases for the treatment of arthritis
|
|
AU751950B2
(en)
|
1997-11-24 |
2002-09-05 |
Merck & Co., Inc. |
Substituted beta-alanine derivatives as cell adhesion inhibitors
|
|
JP2000159751A
(ja)
*
|
1998-11-20 |
2000-06-13 |
Torii Yakuhin Kk |
ベンゼン誘導体
|
|
FR2791982B1
(fr)
*
|
1999-04-06 |
2002-12-27 |
Inst Nat Sante Rech Med |
Inhibiteurs de lta4 hydrolase et leurs applications therapeutiques.
|
|
PL365238A1
(en)
|
2000-02-16 |
2004-12-27 |
Neurogen Corporation |
Substituted arylpyrazines
|
|
FR2812876B1
(fr)
|
2000-08-08 |
2002-09-27 |
Galderma Res & Dev |
Nouveaux composes bi-aromatiques activateurs des recepteurs de type ppar-gamma et leur utilisation dans des compositions cosmetiques ou pharmaceutiques
|
|
ATE409181T1
(de)
|
2001-05-08 |
2008-10-15 |
Univ Yale |
Proteomimetische verbindungen und verfahren
|
|
US6734197B2
(en)
*
|
2001-06-07 |
2004-05-11 |
Wyeth |
Combination therapy for type II diabetes or Syndrome X
|
|
US6908939B2
(en)
|
2001-12-21 |
2005-06-21 |
Galderma Research & Development S.N.C. |
Biaromatic ligand activators of PPARγ receptors
|
|
WO2003066629A2
(en)
|
2002-02-06 |
2003-08-14 |
Vertex Pharmaceuticals Incorporated |
Heteroaryl compounds useful as inhibitors of gsk-3
|
|
DE60325830D1
(de)
|
2002-02-21 |
2009-03-05 |
Asahi Kasei Pharma Corp |
Substituiertes phenylalkansäurederivat und dessen verwendung
|
|
US7638630B2
(en)
|
2002-04-30 |
2009-12-29 |
Ucb Pharma S.A. |
2,6-quinolinyl and 2,6-naphthyl derivatives, processes for preparing them and their uses as VLA-4 inhibitors
|
|
WO2004011442A1
(ja)
*
|
2002-07-29 |
2004-02-05 |
Shizuoka Coffein Co., Ltd. |
ピリミジン誘導体
|
|
DE10250743A1
(de)
*
|
2002-10-31 |
2004-05-19 |
Boehringer Ingelheim Pharma Gmbh & Co. Kg |
Neue Amid-Verbindungen mit MCH-antagonistischer Wirkung und diese Verbindungen enthaltende Arzneimittel
|
|
CA2514363A1
(en)
|
2003-02-12 |
2004-08-26 |
Transtech Pharma, Inc. |
Substituted azole derivatives as therapeutic agents
|
|
SE0301010D0
(sv)
|
2003-04-07 |
2003-04-07 |
Astrazeneca Ab |
Novel compounds
|
|
GB0312654D0
(en)
*
|
2003-06-03 |
2003-07-09 |
Glaxo Group Ltd |
Therapeutically useful compounds
|
|
ATE350369T1
(de)
|
2003-08-20 |
2007-01-15 |
Lilly Co Eli |
Verbindungen, verfahren und formulierungen zur oralen verabreichung einer glucagon like peptide (glp)-1-verbindung oder eines am melanocortin-4- rezeptor (mc4) als agonist wirkenden peptids
|
|
FR2869611B1
(fr)
|
2004-05-03 |
2006-07-28 |
Merck Sante Soc Par Actions Si |
Derives de l'acide hexenoique, procedes pour leur preparation, compositions pharmaceutiques les contenant et applications en therapeutique
|
|
EP1798224A1
(en)
|
2004-10-05 |
2007-06-20 |
Shionogi Co., Ltd. |
Biaryl derivative
|
|
GB0422057D0
(en)
|
2004-10-05 |
2004-11-03 |
Astrazeneca Ab |
Novel compounds
|
|
AP2413A
(en)
|
2005-02-22 |
2012-06-01 |
Ranbaxy Lab Ltd |
5-phenyl-pentanoic acid derivatives as matrix metalloproteinase inhibitors for the treatment of asthma and other disease.
|
|
EP1883652A2
(en)
*
|
2005-05-26 |
2008-02-06 |
Bristol-Myers Squibb Company |
N-terminally modified glp-1 receptor modulators
|
|
CA2618888A1
(en)
*
|
2005-08-10 |
2007-02-15 |
Bayer Schering Pharma Aktiengesellschaft |
Acyltryptophanols for fertility control
|
|
GB0525323D0
(en)
|
2005-12-13 |
2006-01-18 |
Sterix Ltd |
Compound
|
|
JP5564251B2
(ja)
*
|
2006-06-29 |
2014-07-30 |
キネックス ファーマシューティカルズ， エルエルシー |
キナーゼカスケードを調節するためのビアリール組成物および方法
|
|
CA2659956C
(en)
|
2006-08-04 |
2016-01-05 |
Lewis C. Cantley |
Inhibitors of pyruvate kinase and methods of treating disease
|
|
PL2074093T3
(pl)
*
|
2006-08-22 |
2013-03-29 |
Sun Pharmaceutical Ind Ltd |
Sposób przygotowywania inhibitorów metaloproteinazy macierzy i chiralnego środka wspomagającego
|
|
CA2662359A1
(en)
*
|
2006-09-21 |
2008-03-27 |
Novartis Ag |
Pyrrole derivatives useful for the treatment of cytokine-mediated diseases
|
|
KR101107896B1
(ko)
*
|
2006-10-04 |
2012-01-25 |
에프. 호프만-라 로슈 아게 |
고 밀도 지단백질(ｈｄｌ)-콜레스테롤 상승제로서 3-피리딘카복스아마이드 및 2-피라진카복스아마이드 유도체
|
|
EP2079725B1
(en)
*
|
2006-10-27 |
2011-12-14 |
Boehringer Ingelheim International GmbH |
Piperidyl-propane-thiol ccr3 modulators
|
|
AU2007326395B2
(en)
*
|
2006-12-01 |
2012-10-11 |
Msd K.K. |
Novel phenyl-isoxazol-3-ol derivative
|
|
JP2010517935A
(ja)
|
2007-02-09 |
2010-05-27 |
武田薬品工業株式会社 |
Ｐｐａｒ−ガンマのパーシャルアゴニストとしての縮合環化合物
|
|
AU2008218950A1
(en)
*
|
2007-02-22 |
2008-08-28 |
Irm Llc |
Thiazole derivatives as modulators of G protein-coupled receptors
|
|
JP5175866B2
(ja)
*
|
2007-02-22 |
2013-04-03 |
アイアールエム・リミテッド・ライアビリティ・カンパニー |
Ｇタンパク質共役受容体を調節するための化合物および方法
|
|
EP2151236A4
(en)
*
|
2007-04-26 |
2013-01-16 |
Japan Science & Tech Agency |
G-PROTEIN-CONJUGATED RECEPTOR AGONIST
|
|
CL2008001205A1
(es)
*
|
2007-04-27 |
2008-11-14 |
Actelion Pharmaceuticals Ltd |
Compuestos derivados de biciclo[2.2.2]octeno; composicion farmaceutica que los contiene; y uso en el tratamiento o prevencion de angina cronica estable, hipertension, isquemia renal y cardiaca, arritmias cardiacas, hipertrofia cardiaca y falla congestiva del corazon.
|
|
WO2009011285A1
(ja)
*
|
2007-07-13 |
2009-01-22 |
Taisho Pharmaceutical Co., Ltd. |
ヘテロアリールベンゼン化合物
|
|
JP4834699B2
(ja)
|
2007-07-30 |
2011-12-14 |
田辺三菱製薬株式会社 |
医薬組成物
|
|
US7902181B2
(en)
*
|
2007-12-12 |
2011-03-08 |
Astrazeneca Ab |
Compounds 010
|
|
US20110039860A1
(en)
*
|
2008-05-07 |
2011-02-17 |
Cangming Yang |
Soluble epoxide hydrolase inhibitors, compositions containing such compounds and methods of treatment
|
|
CN102076670B
(zh)
|
2008-06-24 |
2013-05-22 |
Irm责任有限公司 |
调节g蛋白偶联受体的化合物和方法
|
|
EA022417B1
(ru)
*
|
2008-10-21 |
2015-12-30 |
Саймабэй Терапевтикс, Инк. |
Арильные агонисты рецептора gpr120 и их применение
|
|
EP2352374B1
(en)
|
2008-10-29 |
2014-09-24 |
Merck Sharp & Dohme Corp. |
Novel cyclic benzimidazole derivatives useful anti-diabetic agents
|
|
TW201031649A
(en)
|
2008-12-02 |
2010-09-01 |
Organon Nv |
1-(4-(pyridin-2-yl)benzyl)imidazolidine-2,4-dione derivatives
|
|
WO2010070076A1
(en)
*
|
2008-12-19 |
2010-06-24 |
Crystax Pharmaceuticals, S.L. |
Alkanoic acid derivatives and their therapeutic use as hdac inhibitors
|
|
CN102421739A
(zh)
|
2009-04-22 |
2012-04-18 |
安斯泰来制药株式会社 |
羧酸化合物
|
|
JP5466759B2
(ja)
*
|
2009-05-28 |
2014-04-09 |
ノバルティス アーゲー |
ネプリライシン阻害剤としての置換アミノ酪酸誘導体
|
|
MX2012005281A
(es)
*
|
2009-11-05 |
2012-06-19 |
Fibrostatin S L |
Inhibicion de gpbp utilizando peptidomimeticos q2.
|
|
ES2526124T3
(es)
*
|
2010-06-16 |
2015-01-07 |
Cymabay Therapeutics, Inc. |
Agonistas del receptor GPR120 y sus usos
|
|
AR081930A1
(es)
*
|
2010-06-16 |
2012-10-31 |
Ardea Biosciences Inc |
Compuestos de tioacetato
|
|
US9394290B2
(en)
|
2010-10-21 |
2016-07-19 |
Universitaet Des Saarlandes Campus Saarbruecken |
Selective CYP11B1 inhibitors for the treatment of cortisol dependent diseases
|
|
US8673974B2
(en)
|
2010-11-16 |
2014-03-18 |
Novartis Ag |
Substituted amino bisphenyl pentanoic acid derivatives as NEP inhibitors
|
|
HUE028051T2
(hu)
|
2010-12-15 |
2016-11-28 |
Theravance Biopharma R&D Ip Llc |
Neprilizin inhibitorok
|
|
JP6097998B2
(ja)
*
|
2010-12-16 |
2017-03-22 |
ベーリンガー インゲルハイム インターナショナル ゲゼルシャフト ミット ベシュレンクテル ハフツング |
ロイコトリエン生成のビアリールアミドインヒビター
|
|
HUE029002T2
(en)
*
|
2010-12-17 |
2017-01-30 |
Mitsubishi Tanabe Pharma Corp |
Continuous aricyclic compounds
|
|
JP5842630B2
(ja)
*
|
2011-03-16 |
2016-01-13 |
株式会社リコー |
カルバゾール誘導体、及び半導体ナノ結晶
|
|
CN103608014A
(zh)
|
2011-03-24 |
2014-02-26 |
罗楹 |
激酶抑制剂在治疗和预防炎症疾病中的用途
|
|
US9145391B2
(en)
*
|
2011-05-10 |
2015-09-29 |
Merck Sharp & Dohme Corp. |
Bipyridylaminopyridines as Syk inhibitors
|
|
WO2013056679A1
(en)
*
|
2011-10-21 |
2013-04-25 |
Beijing Hanmi Pharmaceutical Co., Ltd |
Novel heteroaryl-amino derivatives
|
|
WO2013139341A1
(en)
*
|
2012-03-20 |
2013-09-26 |
Syddansk Universitet |
Gpr120 receptor modulators
|
|
EA201400990A1
(ru)
*
|
2012-04-06 |
2015-01-30 |
Пфайзер Инк. |
Ингибиторы диацилглицеринацилтрансферазы 2
|
|
BR112014030649A2
(pt)
*
|
2012-06-08 |
2017-06-27 |
Gilead Sciences Inc |
inibidores macrocíclicos da flaviviridae vírus
|
|
WO2013185766A1
(en)
*
|
2012-06-15 |
2013-12-19 |
Syddansk Universitet |
Gpr120 receptor modulators
|
|
RU2015116540A
(ru)
|
2012-10-11 |
2016-12-10 |
Мерк Шарп И Доум Корп. |
Замещенные соединения спиропиперидинила, применяемые в качестве агонистов gpr120
|
|
ES2749467T3
(es)
*
|
2012-11-20 |
2020-03-20 |
Biogen Ma Inc |
Agentes moduladores de S1p y/o ATX
|
|
EP2970312B1
(en)
|
2013-03-11 |
2017-11-15 |
The Regents of The University of Michigan |
Bet bromodomain inhibitors and therapeutic methods using the same
|
|
KR20150127208A
(ko)
*
|
2013-03-14 |
2015-11-16 |
브리스톨-마이어스 스큅 컴퍼니 |
비시클로 [2.2.1] 산 gpr120 조절제
|
|
EP3013796B9
(en)
|
2013-06-27 |
2020-07-01 |
LG Chem, Ltd. |
Biaryl derivatives as gpr120 agonists
|
|
US9938222B2
(en)
*
|
2014-09-09 |
2018-04-10 |
Bristol-Myers Squibb Company |
Cyclopropanecarboxylic acid GPR120 modulators
|
|
EP3191463B1
(en)
*
|
2014-09-11 |
2019-10-30 |
Piramal Enterprises Limited |
Fused heterocyclic compounds as gpr120 agonists
|
|
CN106795098B
(zh)
*
|
2014-10-02 |
2020-07-14 |
默加拜奥伍德有限公司 |
α-氨基酰胺衍生化合物及包含其的药物组合物
|